1OK1
| Decay accelerating factor (cd55) : the structure of an intact human complement regulator. | Descriptor: | ACETATE ION, COMPLEMENT DECAY-ACCELERATING FACTOR, GLYCEROL, ... | Authors: | Lukacik, P, Roversi, P, White, J, Esser, D, Smith, G.P, Billington, J, Williams, P.A, Rudd, P.M, Wormald, M.R, Crispin, M.D.M, Radcliffe, C.M, Dwek, R.A, Evans, D.J, Morgan, B.P, Smith, R.A.G, Lea, S.M. | Deposit date: | 2003-07-16 | Release date: | 2004-01-07 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Complement Regulation at the Molecular Level: The Structure of Decay-Accelerating Factor Proc.Natl.Acad.Sci.USA, 101, 2004
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1OK9
| Decay accelerating factor (CD55): The structure of an intact human complement regulator. | Descriptor: | ACETATE ION, CHLORIDE ION, COMPLEMENT DECAY-ACCELERATING FACTOR, ... | Authors: | Lukacik, P, Roversi, P, White, J, Esser, D, Smith, G.P, Billington, J, Williams, P.A, Rudd, P.M, Wormald, M.R, Crispin, M.D.M, Radcliffe, C.M, Dwek, R.A, Evans, D.J, Morgan, B.P, Smith, R.A.G, Lea, S.M. | Deposit date: | 2003-07-21 | Release date: | 2004-01-07 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Complement Regulation at the Molecular Level: The Structure of Decay-Accelerating Factor Proc.Natl.Acad.Sci.USA, 101, 2004
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1OJW
| Decay accelerating factor (CD55): the structure of an intact human complement regulator. | Descriptor: | COMPLEMENT DECAY-ACCELERATING FACTOR, GLYCEROL, SULFATE ION | Authors: | Lukacik, P, Roversi, P, White, J, Esser, D, Smith, G.P, Billington, J, Williams, P.A, Rudd, P.M, Wormald, M.R, Crispin, M.D.M, Radcliffe, C.M, Dwek, C.M, Evans, D.J, Morgan, B.P, Smith, R.A.G, Lea, S.M. | Deposit date: | 2003-07-16 | Release date: | 2004-01-07 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Complement Regulation at the Molecular Level: The Structure of Decay-Accelerating Factor Proc.Natl.Acad.Sci.USA, 101, 2004
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1OJV
| Decay accelerating factor (CD55): the structure of an intact human complement regulator. | Descriptor: | ACETATE ION, COMPLEMENT DECAY-ACCELERATING FACTOR, GLYCEROL, ... | Authors: | Lukacik, P, Roversi, P, White, J, Esser, D, Smith, G.P, Billington, J, Williams, P.A, Rudd, P.M, Wormald, M.R, Crispin, M.D.M, Radcliffe, C.M, Dwek, C.M, Evans, D.J, Morgan, B.P, Smith, R.A.G, Lea, S.M. | Deposit date: | 2003-07-16 | Release date: | 2004-01-07 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Complement Regulation at the Molecular Level: The Structure of Decay-Accelerating Factor Proc.Natl.Acad.Sci.USA, 101, 2004
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1ITM
| ANALYSIS OF THE SOLUTION STRUCTURE OF HUMAN INTERLEUKIN 4 DETERMINED BY HETERONUCLEAR THREE-DIMENSIONAL NUCLEAR MAGNETIC RESONANCE TECHNIQUES | Descriptor: | INTERLEUKIN-4 | Authors: | Redfield, C, Smith, L.J, Boyd, J, Lawrence, G.M.P, Edwards, R.G, Gershater, C.J, Smith, R.A.G, Dobson, C.M. | Deposit date: | 1994-02-28 | Release date: | 1994-05-31 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | Analysis of the solution structure of human interleukin-4 determined by heteronuclear three-dimensional nuclear magnetic resonance techniques. J.Mol.Biol., 238, 1994
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1ITL
| HUMAN INTERLEUKIN 4: THE SOLUTION STRUCTURE OF A FOUR-HELIX-BUNDLE PROTEIN | Descriptor: | INTERLEUKIN-4 | Authors: | Smith, L.J, Redfield, C, Boyd, J, Lawrence, G.M.P, Edwards, R.G, Smith, R.A.G, Dobson, C.M. | Deposit date: | 1992-02-08 | Release date: | 1993-04-15 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | Human interleukin 4. The solution structure of a four-helix bundle protein. J.Mol.Biol., 224, 1992
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1F5Y
| NMR STRUCTURE OF A CONCATEMER OF THE FIRST AND SECOND LIGAND-BINDING MODULES OF THE HUMAN LDL RECEPTOR | Descriptor: | CALCIUM ION, LOW-DENSITY LIPOPROTEIN RECEPTOR | Authors: | Kurniawan, N.D, Atkins, A.R, Brereton, I.M, Kroon, P.A, Smith, R. | Deposit date: | 2000-06-18 | Release date: | 2000-08-30 | Last modified: | 2022-02-16 | Method: | SOLUTION NMR | Cite: | NMR structure of a concatemer of the first and second ligand-binding modules of the human low-density lipoprotein receptor. Protein Sci., 9, 2000
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6XRK
| GH5-4 broad specificity endoglucanase from an uncultured bovine rumen ciliate | Descriptor: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Bingman, C.A, Smith, R.W, Glasgow, E.M, Fox, B.G. | Deposit date: | 2020-07-13 | Release date: | 2020-10-28 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.419 Å) | Cite: | A structural and kinetic survey of GH5_4 endoglucanases reveals determinants of broad substrate specificity and opportunities for biomass hydrolysis. J.Biol.Chem., 295, 2020
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6XSO
| GH5-4 broad specificity endoglucanase from an uncultured bacterium | Descriptor: | (2S)-2-hydroxybutanedioic acid, Cellulase, DI(HYDROXYETHYL)ETHER, ... | Authors: | Bingman, C.A, Smith, R.W, Glasgow, E.M, Fox, B.G. | Deposit date: | 2020-07-15 | Release date: | 2020-11-18 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | A structural and kinetic survey of GH5_4 endoglucanases reveals determinants of broad substrate specificity and opportunities for biomass hydrolysis. J.Biol.Chem., 295, 2020
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6XSU
| GH5-4 broad specificity endoglucanase from Ruminococcus flavefaciens | Descriptor: | ETHANOL, GH5-4 broad specificity endoglucanase | Authors: | Bingman, C.A, Smith, R.W, Glasgow, E.M, Fox, B.G. | Deposit date: | 2020-07-16 | Release date: | 2020-11-18 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.41 Å) | Cite: | A structural and kinetic survey of GH5_4 endoglucanases reveals determinants of broad substrate specificity and opportunities for biomass hydrolysis. J.Biol.Chem., 295, 2020
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7OBM
| Crystal structure of the human Prolyl Endopeptidase-Like protein short form (residues 90-727) | Descriptor: | Prolyl endopeptidase-like | Authors: | Rosier, K, McDevitt, M.T, Brendan, J.F, Marcaida, M.J, Bingman, C.A, Pagliarini, D.J, Creemers, J.W.M, Smith, R.W, Mitochondrial Protein Partnership (MPP) | Deposit date: | 2021-04-22 | Release date: | 2021-11-10 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Prolyl endopeptidase-like is a (thio)esterase involved in mitochondrial respiratory chain function. Iscience, 24, 2021
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6DPS
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3WNR
| Multiple binding modes of benzyl isothiocyanate inhibitor complexed with Macrophage Migration Inhibitory Factor | Descriptor: | CHLORIDE ION, GLYCEROL, Macrophage migration inhibitory factor, ... | Authors: | Spencer, E.S, Dale, E.J, Gommans, A.L, Rutledge, M.T, Gamble, A.B, Smith, R.A.J, Wilbanks, S.M, Hampton, M.B, Tyndall, J.D.A. | Deposit date: | 2013-12-16 | Release date: | 2014-03-05 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.008 Å) | Cite: | Multiple binding modes of isothiocyanates that inhibit macrophage migration inhibitory factor Eur.J.Med.Chem., 93, 2015
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3WNS
| Allyl isothiocyanate inhibitor complexed with Macrophage Migration Inhibitory Factor | Descriptor: | CHLORIDE ION, GLYCEROL, ISOPROPYL ALCOHOL, ... | Authors: | Spencer, E.S, Dale, E.J, Gommans, A.L, Rutledge, M.T, Gamble, A.B, Smith, R.A.J, Wilbanks, S.M, Hampton, M.B, Tyndall, J.D.A. | Deposit date: | 2013-12-16 | Release date: | 2014-03-05 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.658 Å) | Cite: | Multiple binding modes of isothiocyanates that inhibit macrophage migration inhibitory factor Eur.J.Med.Chem., 93, 2015
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1KDU
| SEQUENTIAL 1H NMR ASSIGNMENTS AND SECONDARY STRUCTURE OF THE KRINGLE DOMAIN FROM UROKINASE | Descriptor: | PLASMINOGEN ACTIVATOR | Authors: | Li, X, Bokman, A.M, Llinas, M, Smith, R.A.G, Dobson, C.M. | Deposit date: | 1993-07-15 | Release date: | 1993-10-31 | Last modified: | 2024-06-05 | Method: | SOLUTION NMR | Cite: | Solution structure of the kringle domain from urokinase-type plasminogen activator. J.Mol.Biol., 235, 1994
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1HZ8
| SOLUTION STRUCTURE AND BACKBONE DYNAMICS OF A CONCATEMER OF EGF-HOMOLOGY MODULES OF THE HUMAN LOW DENSITY LIPOPROTEIN RECEPTOR | Descriptor: | CALCIUM ION, LOW DENSITY LIPOPROTEIN RECEPTOR | Authors: | Kurniawan, N.D, Aliabadizadeh, K, Brereton, I.M, Kroon, P.A, Smith, R. | Deposit date: | 2001-01-23 | Release date: | 2001-08-15 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | NMR structure and backbone dynamics of a concatemer of epidermal growth factor homology modules of the human low-density lipoprotein receptor. J.Mol.Biol., 311, 2001
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1I0U
| SOLUTION STRUCTURE AND BACKBONE DYNAMICS OF A CONCATEMER OF EGF-HOMOLOGY MODULES OF THE HUMAN LOW DENSITY LIPOPROTEIN RECEPTOR | Descriptor: | CALCIUM ION, LOW DENSITY LIPOPROTEIN RECEPTOR | Authors: | Kurniawan, N.D, Aliabadizadeh, K, Brereton, I.M, Kroon, P.A, Smith, R. | Deposit date: | 2001-01-29 | Release date: | 2001-08-15 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | NMR structure and backbone dynamics of a concatemer of epidermal growth factor homology modules of the human low-density lipoprotein receptor. J.Mol.Biol., 311, 2001
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8DK0
| Crystal structure of RPA3624, a beta-propeller lactonase from Rhodopseudomonas palustris, with active-site bound (S)gamma-valerolactone | Descriptor: | CALCIUM ION, Gluconolactonase, SODIUM ION, ... | Authors: | Bingman, C.A, Hall, B.W, Smith, R.W, Fox, B.G, Donohue, T.J. | Deposit date: | 2022-07-01 | Release date: | 2023-01-11 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | A broad specificity beta-propeller enzyme from Rhodopseudomonas palustris that hydrolyzes many lactones including gamma-valerolactone. J.Biol.Chem., 299, 2022
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8DJF
| Crystal structure of RPA3624, a beta-propeller lactonase from Rhodopseudomonas palustris, with active-site bound tetrahedral intermediate | Descriptor: | (5S)-5-methyloxolane-2,2-diol, CALCIUM ION, Gluconolactonase, ... | Authors: | Bingman, C.A, Hall, B.W, Smith, R.W, Fox, B.G, Donohue, T.J. | Deposit date: | 2022-06-30 | Release date: | 2023-01-11 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | A broad specificity beta-propeller enzyme from Rhodopseudomonas palustris that hydrolyzes many lactones including gamma-valerolactone. J.Biol.Chem., 299, 2022
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8DJZ
| Crystal structure of RPA3624, a beta-propeller lactonase from Rhodopseudomonas palustris, with active-site bound product | Descriptor: | (4R)-4-hydroxypentanoic acid, CALCIUM ION, Gluconolactonase, ... | Authors: | Bingman, C.A, Hall, B.W, Smith, R.W, Fox, B.G, Donohue, T.J. | Deposit date: | 2022-07-01 | Release date: | 2023-01-11 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | A broad specificity beta-propeller enzyme from Rhodopseudomonas palustris that hydrolyzes many lactones including gamma-valerolactone. J.Biol.Chem., 299, 2022
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3WNT
| Multiple binding modes of benzyl isothiocyanate inhibitor complexed with Macrophage Migration Inhibitory Factor | Descriptor: | ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, N-benzylthioformamide, ... | Authors: | Spencer, E.S, Dale, E.J, Gommans, A.L, Rutledge, M.T, Gamble, A.B, Smith, R.A.J, Wilbanks, S.M, Hampton, M.B, Tyndall, J.D.A. | Deposit date: | 2013-12-16 | Release date: | 2014-03-05 | Last modified: | 2015-04-01 | Method: | X-RAY DIFFRACTION (2.074 Å) | Cite: | Multiple binding modes of isothiocyanates that inhibit macrophage migration inhibitory factor Eur.J.Med.Chem., 93, 2015
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8EW8
| Crystal structure of Saccharomyces cerevisiae Altered Inheritance rate of Mitochondria protein 18 (AIM18p) R123A mutant | Descriptor: | Altered inheritance of mitochondria protein 18, mitochondrial, SULFATE ION | Authors: | Bingman, C.A, Schmitz, J.M, Smith, R.W, Pagliarini, D.J. | Deposit date: | 2022-10-21 | Release date: | 2023-03-22 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Aim18p and Aim46p are chalcone isomerase domain-containing mitochondrial hemoproteins in Saccharomyces cerevisiae. J.Biol.Chem., 299, 2023
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8EW9
| Crystal structure of Saccharomyces cerevisiae Altered Inheritance rate of Mitochondria protein 46 (AIM46p) | Descriptor: | 2-OXOGLUTARIC ACID, Altered inheritance of mitochondria protein 46, mitochondrial | Authors: | Bingman, C.A, Schmitz, J.M, Smith, R.W, Pagliarini, D.J, Mitochondrial Protein Partnership (MPP) | Deposit date: | 2022-10-21 | Release date: | 2023-03-22 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Aim18p and Aim46p are chalcone isomerase domain-containing mitochondrial hemoproteins in Saccharomyces cerevisiae. J.Biol.Chem., 299, 2023
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1H1B
| Crystal structure of human neutrophil elastase complexed with an inhibitor (GW475151) | Descriptor: | (2S)-3-METHYL-2-((2R,3S)-3-[(METHYLSULFONYL)AMINO]-1-{[2-(PYRROLIDIN-1-YLMETHYL)-1,3-OXAZOL-4-YL]CARBONYL}PYRROLIDIN-2-YL)BUTANOIC ACID, LEUKOCYTE ELASTASE, alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Macdonald, S.J.F, Dowle, M.D, Harrison, L.A, Clarke, G.D.E, Inglis, G.G.A, Johnson, M.R, Smith, R.A, Amour, A, Fleetwood, G, Humphreys, D.C, Molloy, C.R, Dixon, M, Godward, R.E, Wonacott, A.J, Singh, O.M.P, Hodgson, S.T, Hardy, G.W. | Deposit date: | 2002-07-05 | Release date: | 2002-08-29 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Discovery of Further Pyrrolidine Trans-Lactams as Inhibitors of Human Neutrophil Elastase (Hne) with Potential as Development Candidates and the Crystal Structure of Hne Complexed with an Inhibitor (Gw475151) J.Med.Chem., 45, 2002
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4OSF
| 4-(2-isothiocyanatoethyl)phenol inhibitor complexed with Macrophage Migration Inhibitory Factor | Descriptor: | CHLORIDE ION, ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, ... | Authors: | Spencer, E.S, Dale, E.J, Gommans, A.L, Vo, C.T, Rutledge, M.T, Nakatani, Y, Gamble, A.B, Smith, R.A.J, Wilbanks, S.M, Hampton, M.B, Tyndall, J.D.A. | Deposit date: | 2014-02-12 | Release date: | 2014-03-12 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.62 Å) | Cite: | Multiple binding modes of isothiocyanates that inhibit macrophage migration inhibitory factor Eur.J.Med.Chem., 93, 2015
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