1EYV
 
 | | THE CRYSTAL STRUCTURE OF NUSB FROM MYCOBACTERIUM TUBERCULOSIS | | 分子名称: | N-UTILIZING SUBSTANCE PROTEIN B HOMOLOG, PHOSPHATE ION | | 著者 | Gopal, B, Haire, L.F, Cox, R.A, Colston, M.J, Major, S, Brannigan, J.A, Smerdon, S.J, Dodson, G.G, TB Structural Genomics Consortium (TBSGC) | | 登録日 | 2000-05-09 | | 公開日 | 2000-05-18 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | The crystal structure of NusB from Mycobacterium tuberculosis.
Nat.Struct.Biol., 7, 2000
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3UN0
 | | Crystal Structure of MDC1 FHA Domain | | 分子名称: | Mediator of DNA damage checkpoint protein 1, SULFATE ION | | 著者 | Clapperton, J.A, Lloyd, J, Haire, L.F, Li, J, Smerdon, S.J. | | 登録日 | 2011-11-15 | | 公開日 | 2011-12-28 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | The molecular basis of ATM-dependent dimerization of the Mdc1 DNA damage checkpoint mediator.
Nucleic Acids Res., 40, 2012
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3UOT
 | | Crystal Structure of MDC1 FHA Domain in Complex with a Phosphorylated Peptide from the MDC1 N-terminus | | 分子名称: | Mediator of DNA damage checkpoint protein 1 | | 著者 | Clapperton, J.A, Lloyd, J, Haire, L.F, Li, J, Smerdon, S.J. | | 登録日 | 2011-11-17 | | 公開日 | 2011-12-28 | | 最終更新日 | 2012-07-18 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | The molecular basis of ATM-dependent dimerization of the Mdc1 DNA damage checkpoint mediator.
Nucleic Acids Res., 40, 2012
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3I0N
 | | Structure of the S. pombe Nbs1 FHA/BRCT-repeat domain | | 分子名称: | DNA repair and telomere maintenance protein nbs1, GLYCEROL | | 著者 | Clapperton, J.A, Lloyd, J, Chapman, J.R, Jackson, S.P, Smerdon, S.J. | | 登録日 | 2009-06-25 | | 公開日 | 2009-10-13 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | A supramodular FHA/BRCT-repeat architecture mediates Nbs1 adaptor function in response to DNA damage
Cell(Cambridge,Mass.), 139, 2009
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3I0M
 | | Structure of the S. pombe Nbs1 FHA/BRCT-repeat domain | | 分子名称: | DNA repair and telomere maintenance protein nbs1, GLYCEROL | | 著者 | Clapperton, J.A, Lloyd, J, Chapman, J.R, Jackson, S.P, Smerdon, S.J. | | 登録日 | 2009-06-25 | | 公開日 | 2009-10-13 | | 最終更新日 | 2012-05-02 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | A supramodular FHA/BRCT-repeat architecture mediates Nbs1 adaptor function in response to DNA damage
Cell(Cambridge,Mass.), 139, 2009
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3KT9
 | | Aprataxin FHA Domain | | 分子名称: | Aprataxin | | 著者 | Cherry, A.L, Smerdon, S.J. | | 登録日 | 2009-11-24 | | 公開日 | 2010-01-26 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | CK2 phosphorylation-dependent interaction between aprataxin and MDC1 in the DNA damage response.
Nucleic Acids Res., 38, 2010
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2AZM
 | | Crystal structure of the MDC1 brct repeat in complex with the histone tail of gamma-H2AX | | 分子名称: | GAMMA-H2AX HISTONE, Mediator of DNA damage checkpoint protein 1 | | 著者 | Clapperton, J.A, Stucki, M, Mohammad, D, Yaffe, M.B, Jackson, S.P, Smerdon, S.J. | | 登録日 | 2005-09-12 | | 公開日 | 2006-01-31 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | | 主引用文献 | MDC1 Directly Binds Phosphorylated Histone H2AX to Regulate Cellular Responses to DNA Double-Strand Breaks
Cell(Cambridge,Mass.), 123, 2005
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1TX4
 | | RHO/RHOGAP/GDP(DOT)ALF4 COMPLEX | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, P50-RHOGAP, ... | | 著者 | Rittinger, K, Walker, P.A, Smerdon, S.J, Gamblin, S.J. | | 登録日 | 1997-07-29 | | 公開日 | 1998-09-16 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Structure at 1.65 A of RhoA and its GTPase-activating protein in complex with a transition-state analogue.
Nature, 389, 1997
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1RGP
 | | GTPASE-ACTIVATION DOMAIN FROM RHOGAP | | 分子名称: | RHOGAP | | 著者 | Barrett, T, Xiao, B, Dodson, E.J, Dodson, G, Ludbrook, S.B, Nurmahomed, K, Gamblin, S.J, Musacchio, A, Smerdon, S.J, Eccleston, J.F. | | 登録日 | 1996-12-05 | | 公開日 | 1997-10-15 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The structure of the GTPase-activating domain from p50rhoGAP.
Nature, 385, 1997
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1OW3
 | | Crystal Structure of RhoA.GDP.MgF3-in Complex with RhoGAP | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Rho-GTPase-activating protein 1, ... | | 著者 | Graham, D.L, Lowe, P.N, Grime, G.W, Marsh, M, Rittinger, K, Smerdon, S.J, Gamblin, S.J, Eccleston, J.F. | | 登録日 | 2003-03-28 | | 公開日 | 2003-05-06 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | MgF(3)(-) as a Transition State Analog of Phosphoryl Transfer
Chem.Biol., 9, 2002
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1QJA
 | | 14-3-3 ZETA/PHOSPHOPEPTIDE COMPLEX (MODE 2) | | 分子名称: | 14-3-3 PROTEIN ZETA, PHOSPHOPEPTIDE | | 著者 | Rittinger, K, Budman, J, Xu, J, Volinia, S, Cantley, L.C, Smerdon, S.J, Gamblin, S.J, Yaffe, M.B. | | 登録日 | 1999-06-23 | | 公開日 | 1999-09-15 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural Analysis of 14-3-3 Phosphopeptide Complexes Identifies a Dual Role for the Nuclear Export Signal of 14-3-3 in Ligand Binding
Mol.Cell, 4, 1999
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1QJB
 | | 14-3-3 ZETA/PHOSPHOPEPTIDE COMPLEX (MODE 1) | | 分子名称: | 14-3-3 PROTEIN ZETA/DELTA, PHOSPHOPEPTIDE | | 著者 | Rittinger, K, Budman, J, Xu, J, Volinia, S, Cantley, L.C, Smerdon, S.J, Gamblin, S.J, Yaffe, M.B. | | 登録日 | 1999-06-23 | | 公開日 | 1999-09-15 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural Analysis of 14-3-3 Phosphopeptide Complexes Identifies a Dual Role for the Nuclear Export Signal of 14-3-3 in Ligand Binding
Mol.Cell, 4, 1999
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3PO8
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3POA
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1GXC
 | | FHA domain from human Chk2 kinase in complex with a synthetic phosphopeptide | | 分子名称: | SERINE/THREONINE-PROTEIN KINASE CHK2, SYNTHETIC PHOSPHOPEPTIDE | | 著者 | Li, J, Williams, B.L, Haire, L.F, Goldberg, M, Wilker, E, Durocher, D, Yaffe, M.B, Jackson, S.P, Smerdon, S.J. | | 登録日 | 2002-04-02 | | 公開日 | 2002-06-13 | | 最終更新日 | 2016-12-21 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural and Functional Versatility of the Fha Domain in DNA-Damage Signaling by the Tumor Suppressor Kinase Chk2
Mol.Cell, 9, 2002
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1I4T
 | | CRYSTAL STRUCTURE ANALYSIS OF RAC1-GMPPNP IN COMPLEX WITH ARFAPTIN | | 分子名称: | ARFAPTIN 2, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | | 著者 | Tarricone, C, Xiao, B, Justin, N, Gamblin, S.J, Smerdon, S.J. | | 登録日 | 2001-02-23 | | 公開日 | 2001-05-16 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | The structural basis of Arfaptin-mediated cross-talk between Rac and Arf signalling pathways.
Nature, 411, 2001
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1I4L
 | | CRYSTAL STRUCTURE ANALYSIS OF RAC1-GDP IN COMPLEX WITH ARFAPTIN (P41) | | 分子名称: | ARFAPTIN 2, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Tarricone, C, Xiao, B, Justin, N, Gamblin, S.J, Smerdon, S.J. | | 登録日 | 2001-02-22 | | 公開日 | 2001-05-16 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | The structural basis of Arfaptin-mediated cross-talk between Rac and Arf signalling pathways.
Nature, 411, 2001
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1I4D
 | | CRYSTAL STRUCTURE ANALYSIS OF RAC1-GDP COMPLEXED WITH ARFAPTIN (P21) | | 分子名称: | ARFAPTIN 2, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Tarricone, C, Xiao, B, Justin, N, Gamblin, S.J, Smerdon, S.J. | | 登録日 | 2001-02-20 | | 公開日 | 2001-05-16 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | The structural basis of Arfaptin-mediated cross-talk between Rac and Arf signalling pathways.
Nature, 411, 2001
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1I49
 | | CRYSTAL STRUCTURE ANALYSIS OF ARFAPTIN | | 分子名称: | ARFAPTIN 2 | | 著者 | Tarricone, C, Xiao, B, Justin, N, Gamblin, S.J, Smerdon, S.J. | | 登録日 | 2001-02-20 | | 公開日 | 2001-05-16 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | The structural basis of Arfaptin-mediated cross-talk between Rac and Arf signalling pathways.
Nature, 411, 2001
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1NG2
 | | Structure of autoinhibited p47phox | | 分子名称: | Neutrophil cytosolic factor 1 | | 著者 | Groemping, Y, Lapouge, K, Smerdon, S.J, Rittinger, K. | | 登録日 | 2002-12-16 | | 公開日 | 2003-05-20 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Molecular basis of phosphorylation-induced activation of the NADPH oxidase
Cell(Cambridge,Mass.), 113, 2003
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1OV3
 | | Structure of the p22phox-p47phox complex | | 分子名称: | Flavocytochrome b558 alpha polypeptide, Neutrophil cytosol factor 1 | | 著者 | Groemping, Y, Lapouge, K, Smerdon, S.J, Rittinger, K. | | 登録日 | 2003-03-25 | | 公開日 | 2003-05-20 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Molecular basis of phosphorylation-induced activation of the NADPH oxidase
Cell(Cambridge,Mass.), 113, 2003
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1U7K
 | | Structure of a hexameric N-terminal domain from murine leukemia virus capsid | | 分子名称: | Gag polyprotein | | 著者 | Mortuza, G.B, Haire, L.F, Stevens, A, Smerdon, S.J, Stoye, J.P, Taylor, I.A. | | 登録日 | 2004-08-04 | | 公開日 | 2004-10-05 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | High-resolution structure of a retroviral capsid hexameric amino-terminal domain.
Nature, 431, 2004
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1UMW
 | | Structure of a human Plk1 Polo-box domain/phosphopeptide complex | | 分子名称: | PEPTIDE, SERINE/THREONINE-PROTEIN KINASE PLK | | 著者 | Rellos, P, Elia, A, Yaffe, M.B, Smerdon, S.J. | | 登録日 | 2003-08-29 | | 公開日 | 2003-10-16 | | 最終更新日 | 2017-02-08 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The Molecular Basis for Phosphodependent Substrate Targeting and Regulation of Plks by the Polo-Box Domain
Cell(Cambridge,Mass.), 115, 2003
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1T15
 | | Crystal Structure of the Brca1 BRCT Domains in Complex with the Phosphorylated Interacting Region from Bach1 Helicase | | 分子名称: | BRCA1 interacting protein C-terminal helicase 1, Breast cancer type 1 susceptibility protein | | 著者 | Clapperton, J.A, Manke, I.A, Lowery, D.M, Ho, T, Haire, L.F, Yaffe, M.B, Smerdon, S.J. | | 登録日 | 2004-04-15 | | 公開日 | 2004-05-11 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Structure and mechanism of BRCA1 BRCT domain recognition of phosphorylated BACH1 with implications for cancer
Nat.Struct.Mol.Biol., 11, 2004
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1SW6
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