2HMG
 
 | | REFINEMENT OF THE INFLUENZA VIRUS HEMAGGLUTININ BY SIMULATED ANNEALING | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, HEMAGGLUTININ (HA1 CHAIN), HEMAGGLUTININ (HA2 CHAIN), ... | | 著者 | Weis, W.I, Bruenger, A.T, Skehel, J.J, Wiley, D.C. | | 登録日 | 1989-09-11 | | 公開日 | 1991-01-15 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Refinement of the influenza virus hemagglutinin by simulated annealing.
J.Mol.Biol., 212, 1990
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6TWS
 | | Crystal structure of the haemagglutinin mutant (Gln226Leu, Gly228Ser) from an H10N7 seal influenza virus isolated in Germany with 2mM EDTA | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Zhang, J, Xiong, X, Purkiss, A, Walker, P, Gamblin, S, Skehel, J.J. | | 登録日 | 2020-01-13 | | 公開日 | 2020-10-21 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Hemagglutinin Traits Determine Transmission of Avian A/H10N7 Influenza Virus between Mammals.
Cell Host Microbe, 28, 2020
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1QU1
 | | CRYSTAL STRUCTURE OF EHA2 (23-185) | | 分子名称: | PROTEIN (INFLUENZA RECOMBINANT HA2 CHAIN) | | 著者 | Chen, J, Skehel, J.J, Wiley, D.C. | | 登録日 | 1999-07-05 | | 公開日 | 2000-01-05 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | N- and C-terminal residues combine in the fusion-pH influenza hemagglutinin HA(2) subunit to form an N cap that terminates the triple-stranded coiled coil.
Proc.Natl.Acad.Sci.USA, 96, 1999
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2VIS
 | | INFLUENZA VIRUS HEMAGGLUTININ, (ESCAPE) MUTANT WITH THR 131 REPLACED BY ILE, COMPLEXED WITH A NEUTRALIZING ANTIBODY | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, HEMAGGLUTININ, IMMUNOGLOBULIN (IGG1, ... | | 著者 | Bizebard, T, Fleury, D, Gigant, B, Wharton, S.A, Skehel, J.J, Knossow, M. | | 登録日 | 1997-12-22 | | 公開日 | 1998-04-29 | | 最終更新日 | 2021-11-03 | | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | | 主引用文献 | Antigen distortion allows influenza virus to escape neutralization.
Nat.Struct.Biol., 5, 1998
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2VIR
 | | INFLUENZA VIRUS HEMAGGLUTININ COMPLEXED WITH A NEUTRALIZING ANTIBODY | | 分子名称: | HEMAGGLUTININ, IMMUNOGLOBULIN (IGG1, LAMBDA), ... | | 著者 | Bizebard, T, Fleury, D, Gigant, B, Wharton, S.A, Skehel, J.J, Knossow, M. | | 登録日 | 1997-12-22 | | 公開日 | 1998-04-29 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | | 主引用文献 | Antigen distortion allows influenza virus to escape neutralization.
Nat.Struct.Biol., 5, 1998
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2VIU
 | | INFLUENZA VIRUS HEMAGGLUTININ | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, HEMAGGLUTININ, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | 著者 | Bizebard, T, Fleury, D, Gigant, B, Wharton, S.A, Skehel, J.J, Knossow, M. | | 登録日 | 1997-12-22 | | 公開日 | 1998-04-29 | | 最終更新日 | 2021-11-03 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Antigen distortion allows influenza virus to escape neutralization.
Nat.Struct.Biol., 5, 1998
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2VIT
 | | INFLUENZA VIRUS HEMAGGLUTININ, MUTANT WITH THR 155 REPLACED BY ILE, COMPLEXED WITH A NEUTRALIZING ANTIBODY | | 分子名称: | HEMAGGLUTININ, IMMUNOGLOBULIN (IGG1, LAMBDA), ... | | 著者 | Bizebard, T, Fleury, D, Gigant, B, Wharton, S.A, Skehel, J.J, Knossow, M. | | 登録日 | 1997-12-22 | | 公開日 | 1998-04-29 | | 最終更新日 | 2021-11-03 | | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | | 主引用文献 | Antigen distortion allows influenza virus to escape neutralization.
Nat.Struct.Biol., 5, 1998
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1KEN
 | | INFLUENZA VIRUS HEMAGGLUTININ COMPLEXED WITH AN ANTIBODY THAT PREVENTS THE HEMAGGLUTININ LOW PH FUSOGENIC TRANSITION | | 分子名称: | alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, hemagglutinin HA1, hemagglutinin HA2, ... | | 著者 | Barbey-Martin, C, Gigant, B, Bizebard, T, Calder, L.J, Wharto, S.A, Skehel, J.J, Knossow, M. | | 登録日 | 2001-11-16 | | 公開日 | 2002-04-24 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | An Antibody that Prevents the Hemagglutinin Low pH Fusogenic Transition
VIROLOGY, 294, 2002
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5JW5
 | | Structure of MEDI8852 Fab Fragment | | 分子名称: | MEDI8852 Heavy chain, MEDI8852 Light chain, PHOSPHATE ION | | 著者 | Neu, U, Collins, P.J, Walker, P.A, Vorlaender, M.K, Ogrodowicz, R.W, Martin, S.R, Gamblin, S.J, Skehel, J.J. | | 登録日 | 2016-05-11 | | 公開日 | 2016-08-03 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure and Function Analysis of an Antibody Recognizing All Influenza A Subtypes.
Cell, 166, 2016
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5JW3
 | | Structure of MEDI8852 Fab Fragment in Complex with H7 HA | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... | | 著者 | Collins, P.J, Neu, U, Walker, P.A, Vorlaender, M.K, Ogrodowicz, R.W, Martin, S.R, Gamblin, S.J, Skehel, J.J. | | 登録日 | 2016-05-11 | | 公開日 | 2016-08-03 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3.75 Å) | | 主引用文献 | Structure and Function Analysis of an Antibody Recognizing All Influenza A Subtypes.
Cell, 166, 2016
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5JW4
 | | Structure of MEDI8852 Fab Fragment in Complex with H5 HA | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... | | 著者 | Neu, U, Collins, P.J, Walker, P.A, Vorlaender, M.K, Ogrodowicz, R.W, Martin, S.R, Gamblin, S.J, Skehel, J.J. | | 登録日 | 2016-05-11 | | 公開日 | 2016-08-03 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | | 主引用文献 | Structure and Function Analysis of an Antibody Recognizing All Influenza A Subtypes.
Cell, 166, 2016
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1EBO
 | | CRYSTAL STRUCTURE OF THE EBOLA VIRUS MEMBRANE-FUSION SUBUNIT, GP2, FROM THE ENVELOPE GLYCOPROTEIN ECTODOMAIN | | 分子名称: | CHLORIDE ION, EBOLA VIRUS ENVELOPE PROTEIN CHIMERA CONSISTING OF A FRAGMENT OF GCN4 ZIPPER CLONED N-TERMINAL TO A FRAGMENT OF GP2, ZINC ION | | 著者 | Weissenhorn, W, Carfi, A, Lee, K.H, Skehel, J.J, Wiley, D.C. | | 登録日 | 1998-11-03 | | 公開日 | 1999-07-02 | | 最終更新日 | 2022-12-21 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Crystal structure of the Ebola virus membrane fusion subunit, GP2, from the envelope glycoprotein ectodomain.
Mol.Cell, 2, 1998
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1ENV
 | | ATOMIC STRUCTURE OF THE ECTODOMAIN FROM HIV-1 GP41 | | 分子名称: | HIV-1 ENVELOPE PROTEIN CHIMERA CONSISTING OF A FRAGMENT OF GCN4 ZIPPER CLONED N-TERMINAL TO TWO FRAGMENTS OF GP41 | | 著者 | Weissenhorn, W, Dessen, A, Harrison, S.C, Skehel, J.J, Wiley, D.C. | | 登録日 | 1997-06-27 | | 公開日 | 1997-11-19 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Atomic structure of the ectodomain from HIV-1 gp41.
Nature, 387, 1997
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3EYM
 | | Structure of Influenza Haemagglutinin in complex with an inhibitor of membrane fusion | | 分子名称: | 2-tert-butylbenzene-1,4-diol, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain | | 著者 | Russell, R.J, Kerry, P.S, Stevens, D.A, Steinhauer, D.A, Martin, S.R, Gamblin, S.J, Skehel, J.J. | | 登録日 | 2008-10-21 | | 公開日 | 2009-01-13 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structure of influenza hemagglutinin in complex with an inhibitor of membrane fusion
Proc.Natl.Acad.Sci.USA, 105, 2008
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1JSI
 | | CRYSTAL STRUCTURE OF H9 HAEMAGGLUTININ BOUND TO LSTC RECEPTOR ANALOG | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Ha, Y, Stevens, D.J, Skehel, J.J, Wiley, D.C. | | 登録日 | 2001-08-17 | | 公開日 | 2001-09-26 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | X-ray structures of H5 avian and H9 swine influenza virus hemagglutinins bound to avian and human receptor analogs.
Proc.Natl.Acad.Sci.USA, 98, 2001
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3EYJ
 | | Structure of Influenza Haemagglutinin in complex with an inhibitor of membrane fusion | | 分子名称: | Hemagglutinin HA1 chain, Hemagglutinin HA2 chain | | 著者 | Russell, R.J, Kerry, P.S, Stevens, D.J, Steinahuer, D.A, Martin, S.R, Gamblin, S.J, Skehel, J.J. | | 登録日 | 2008-10-21 | | 公開日 | 2009-01-13 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structure of influenza hemagglutinin in complex with an inhibitor of membrane fusion
Proc.Natl.Acad.Sci.USA, 105, 2008
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1JSN
 | | STRUCTURE OF AVIAN H5 HAEMAGGLUTININ COMPLEXED WITH LSTA RECEPTRO ANALOG | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HAEMAGGLUTININ (HA1 CHAIN), ... | | 著者 | Ha, Y, Stevens, D.J, Skehel, J.J, Wiley, D.C. | | 登録日 | 2001-08-17 | | 公開日 | 2001-09-26 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | X-ray structures of H5 avian and H9 swine influenza virus hemagglutinins bound to avian and human receptor analogs.
Proc.Natl.Acad.Sci.USA, 98, 2001
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3EYK
 | | Structure of Influenza Haemagglutinin in complex with an inhibitor of membrane fusion | | 分子名称: | 2-tert-butylbenzene-1,4-diol, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain | | 著者 | Russell, R.J, Kerry, P.S, Stevens, D.J, Steinhauer, D.A, Martin, S.R, Gamblin, S.J, Skehel, J.J. | | 登録日 | 2008-10-21 | | 公開日 | 2009-01-13 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structure of influenza hemagglutinin in complex with an inhibitor of membrane fusion
Proc.Natl.Acad.Sci.USA, 105, 2008
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3CL0
 | | N1 Neuraminidase H274Y + oseltamivir | | 分子名称: | (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, CALCIUM ION, Neuraminidase | | 著者 | Collins, P, Haire, L.F, Lin, Y.P, Liu, J, Russell, R.J, Walker, P.A, Skehel, J.J, Martin, S.R, Hay, A.J, Gamblin, S.J. | | 登録日 | 2008-03-18 | | 公開日 | 2008-05-20 | | 最終更新日 | 2018-08-22 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structures of oseltamivir-resistant influenza virus neuraminidase mutants.
Nature, 453, 2008
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3CKZ
 | | N1 Neuraminidase H274Y + Zanamivir | | 分子名称: | CALCIUM ION, Neuraminidase, ZANAMIVIR | | 著者 | Colllins, P, Haire, L.F, Lin, Y.P, Liu, J, Russell, R.J, Walker, P.A, Skehel, J.J, Martin, S.R, Hay, A.J, Gamblin, S.J. | | 登録日 | 2008-03-18 | | 公開日 | 2008-05-20 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structures of oseltamivir-resistant influenza virus neuraminidase mutants.
Nature, 453, 2008
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1HA0
 | | HEMAGGLUTININ PRECURSOR HA0 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, PROTEIN (HEMAGGLUTININ PRECURSOR), alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Chen, J, Ho Lee, K, Steinhauer, D.A, Stevens, D.J, Skehel, J.J, Wiley, D.C. | | 登録日 | 1998-10-08 | | 公開日 | 1998-10-12 | | 最終更新日 | 2021-11-03 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structure of the hemagglutinin precursor cleavage site, a determinant of influenza pathogenicity and the origin of the labile conformation.
Cell(Cambridge,Mass.), 95, 1998
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3CL2
 | | N1 Neuraminidase N294S + Oseltamivir | | 分子名称: | (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, Neuraminidase | | 著者 | Collins, P, Haire, L.F, Lin, Y.P, Liu, J, Russell, R.J, Walker, P.A, Skehel, J.J, Martin, S.R, Hay, A.J, Gamblin, S.J. | | 登録日 | 2008-03-18 | | 公開日 | 2008-05-20 | | 最終更新日 | 2018-08-22 | | 実験手法 | X-RAY DIFFRACTION (2.538 Å) | | 主引用文献 | Crystal structures of oseltamivir-resistant influenza virus neuraminidase mutants.
Nature, 453, 2008
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1JSD
 | | CRYSTAL STRUCTURE OF SWINE H9 HAEMAGGLUTININ | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HAEMAGGLUTININ (HA1 CHAIN), ... | | 著者 | Ha, Y, Steven, D.J, Skehel, J.J, Wiley, D.C. | | 登録日 | 2001-08-17 | | 公開日 | 2001-09-26 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | H5 avian and H9 swine influenza virus haemagglutinin structures: possible origin of influenza subtypes.
EMBO J., 21, 2002
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1JSH
 | | CRYSTAL STRUCTURE OF H9 HAEMAGGLUTININ COMPLEXED WITH LSTA RECEPTOR ANALOG | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Ha, Y, Stevens, D.J, Skehel, J.J, Wiley, D.C. | | 登録日 | 2001-08-17 | | 公開日 | 2001-09-26 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | X-ray structures of H5 avian and H9 swine influenza virus hemagglutinins bound to avian and human receptor analogs.
Proc.Natl.Acad.Sci.USA, 98, 2001
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1JSM
 | | STRUCTURE OF H5 AVIAN HAEMAGGLUTININ | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HAEMAGGLUTININ (HA1 CHAIN), ... | | 著者 | Ha, Y, Stevens, D.J, Skehel, J.J, Wiley, D.C. | | 登録日 | 2001-08-17 | | 公開日 | 2001-09-26 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | H5 avian and H9 swine influenza virus haemagglutinin structures: possible origin of influenza subtypes.
EMBO J., 21, 2002
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