7PCK
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5JYO
| Allosteric inhibition of Kidney Isoform of Glutaminase | 分子名称: | 2-(pyridin-2-yl)-N-(5-{4-[6-({[3-(trifluoromethoxy)phenyl]acetyl}amino)pyridazin-3-yl]butyl}-1,3,4-thiadiazol-2-yl)acetamide, Glutaminase kidney isoform, mitochondrial | 著者 | Sivaraman, J, Jayaraman, S. | 登録日 | 2016-05-15 | 公開日 | 2016-08-03 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.098 Å) | 主引用文献 | Structural basis for exploring the allosteric inhibition of human kidney type glutaminase. Oncotarget, 7, 2016
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5DIN
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1ZPS
| Crystal structure of Methanobacterium thermoautotrophicum phosphoribosyl-AMP cyclohydrolase HisI | 分子名称: | ACETIC ACID, CADMIUM ION, Phosphoribosyl-AMP cyclohydrolase | 著者 | Sivaraman, J, Myers, R.S, Boju, L, Sulea, T, Cygler, M, Davisson, V.J, Schrag, J.D, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) | 登録日 | 2005-05-17 | 公開日 | 2005-08-30 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystal Structure of Methanobacterium thermoautotrophicum Phosphoribosyl-AMP Cyclohydrolase HisI. Biochemistry, 44, 2005
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6JX6
| Tetrameric form of Smac | 分子名称: | Diablo homolog, mitochondrial | 著者 | Sivaraman, J, Singh, S, Ng, J, Nayak, D. | 登録日 | 2019-04-22 | 公開日 | 2019-12-04 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.805 Å) | 主引用文献 | Structural insights into a HECT-type E3 ligase AREL1 and its ubiquitination activitiesin vitro. J.Biol.Chem., 294, 2019
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6JX5
| Hect domain of AREL1 | 分子名称: | Apoptosis-resistant E3 ubiquitin protein ligase 1 | 著者 | Sivaraman, J, Singh, S, Ng, J, Nayak, D. | 登録日 | 2019-04-22 | 公開日 | 2019-12-04 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.402 Å) | 主引用文献 | Structural insights into a HECT-type E3 ligase AREL1 and its ubiquitination activitiesin vitro. J.Biol.Chem., 294, 2019
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5IAO
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3LCV
| Crystal Structure of Antibiotic related Methyltransferase | 分子名称: | S-ADENOSYLMETHIONINE, Sisomicin-gentamicin resistance methylase Sgm | 著者 | Sivaraman, J, Husain, N. | 登録日 | 2010-01-11 | 公開日 | 2010-06-02 | 最終更新日 | 2017-11-01 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural basis for the methylation of G1405 in 16S rRNA by aminoglycoside resistance methyltransferase Sgm from an antibiotic producer: a diversity of active sites in m7G methyltransferases. Nucleic Acids Res., 2010
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3LCU
| Crystal Structure of Antibiotic related Methyltransferase | 分子名称: | S-ADENOSYL-L-HOMOCYSTEINE, Sisomicin-gentamicin resistance methylase Sgm | 著者 | Sivaraman, J, Husain, N. | 登録日 | 2010-01-11 | 公開日 | 2010-06-02 | 最終更新日 | 2017-11-01 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural basis for the methylation of G1405 in 16S rRNA by aminoglycoside resistance methyltransferase Sgm from an antibiotic producer: a diversity of active sites in m7G methyltransferases. Nucleic Acids Res., 2010
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6K2C
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2R60
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2R66
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2R68
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1PS6
| Crystal structure of E.coli PdxA | 分子名称: | 4-HYDROXY-L-THREONINE-5-MONOPHOSPHATE, 4-hydroxythreonine-4-phosphate dehydrogenase, ZINC ION | 著者 | Sivaraman, J, Li, Y, Banks, J, Cane, D.E, Matte, A, Cygler, M. | 登録日 | 2003-06-20 | 公開日 | 2003-11-04 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Crystal Structure of Escherichia coli PdxA, an Enzyme Involved in the Pyridoxal Phosphate Biosynthesis Pathway J.Biol.Chem., 278, 2003
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1PS7
| Crystal structure of E.coli PdxA | 分子名称: | 4-hydroxythreonine-4-phosphate dehydrogenase, ZINC ION | 著者 | Sivaraman, J, Li, Y, Banks, J, Cane, D.E, Matte, A, Cygler, M. | 登録日 | 2003-06-20 | 公開日 | 2003-11-04 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.47 Å) | 主引用文献 | Crystal Structure of Escherichia coli PdxA, an Enzyme Involved in the Pyridoxal Phosphate Biosynthesis Pathway J.Biol.Chem., 278, 2003
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1PTM
| Crystal structure of E.coli PdxA | 分子名称: | 4-hydroxythreonine-4-phosphate dehydrogenase, PHOSPHATE ION, ZINC ION | 著者 | Sivaraman, J, Li, Y, Banks, J, Cane, D.E, Matte, A, Cygler, M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) | 登録日 | 2003-06-23 | 公開日 | 2003-11-04 | 最終更新日 | 2017-10-11 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | Crystal Structure of Escherichia coli PdxA, an Enzyme Involved in the Pyridoxal Phosphate Biosynthesis Pathway J.Biol.Chem., 278, 2003
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3VK6
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1IJI
| Crystal Structure of L-Histidinol Phosphate Aminotransferase with PLP | 分子名称: | Histidinol Phosphate Aminotransferase, PYRIDOXAL-5'-PHOSPHATE | 著者 | Sivaraman, J, Li, Y, Larocque, R, Schrag, J.D, Cygler, M, Matte, A. | 登録日 | 2001-04-26 | 公開日 | 2001-08-29 | 最終更新日 | 2017-10-04 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structure of histidinol phosphate aminotransferase (HisC) from Escherichia coli, and its covalent complex with pyridoxal-5'-phosphate and l-histidinol phosphate. J.Mol.Biol., 311, 2001
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1KSL
| STRUCTURE OF RSUA | 分子名称: | RIBOSOMAL SMALL SUBUNIT PSEUDOURIDINE SYNTHASE A, URACIL | 著者 | Sivaraman, J, Sauve, V, Larocque, R, Stura, E.A, Schrag, J.D, Cygler, M, Matte, A, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) | 登録日 | 2002-01-13 | 公開日 | 2002-04-24 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure of the 16S rRNA pseudouridine synthase RsuA bound to uracil and UMP. Nat.Struct.Biol., 9, 2002
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1KSV
| STRUCTURE OF RSUA | 分子名称: | RIBOSOMAL SMALL SUBUNIT PSEUDOURIDINE SYNTHASE A, URIDINE-5'-MONOPHOSPHATE | 著者 | Sivaraman, J, Sauve, V, Larocque, R, Stura, E.A, Schrag, J.D, Cygler, M, Matte, A. | 登録日 | 2002-01-14 | 公開日 | 2002-04-24 | 最終更新日 | 2018-01-31 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Structure of the 16S rRNA pseudouridine synthase RsuA bound to uracil and UMP. Nat.Struct.Biol., 9, 2002
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1KSK
| STRUCTURE OF RSUA | 分子名称: | RIBOSOMAL SMALL SUBUNIT PSEUDOURIDINE SYNTHASE A, URACIL | 著者 | Sivaraman, J, Sauve, V, Larocque, R, Stura, E.A, Schrag, J.D, Cygler, M, Matte, A. | 登録日 | 2002-01-13 | 公開日 | 2002-04-24 | 最終更新日 | 2018-01-31 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure of the 16S rRNA pseudouridine synthase RsuA bound to uracil and UMP. Nat.Struct.Biol., 9, 2002
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1PRZ
| Crystal structure of pseudouridine synthase RluD catalytic module | 分子名称: | Ribosomal large subunit pseudouridine synthase D | 著者 | Sivaraman, J, Iannuzzi, P, Cygler, M, Matte, A, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) | 登録日 | 2003-06-20 | 公開日 | 2003-11-04 | 最終更新日 | 2017-10-11 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal structure of the RluD pseudouridine Synthase catalytic module, an
enzyme that modifies 23S rRNA and is essential for normal cell growth of Escherichia coli J.Mol.Biol., 335, 2003
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1DEU
| CRYSTAL STRUCTURE OF HUMAN PROCATHEPSIN X: A CYSTEINE PROTEASE WITH THE PROREGION COVALENTLY LINKED TO THE ACTIVE SITE CYSTEINE | 分子名称: | PROCATHEPSIN X | 著者 | Sivaraman, J, Nagler, D.K, Zhang, R, Menard, R, Cygler, M. | 登録日 | 1999-11-15 | 公開日 | 2000-02-18 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystal structure of human procathepsin X: a cysteine protease with the proregion covalently linked to the active site cysteine. J.Mol.Biol., 295, 2000
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1FG7
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1FG3
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