7PCK
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1ZPS
| Crystal structure of Methanobacterium thermoautotrophicum phosphoribosyl-AMP cyclohydrolase HisI | Descriptor: | ACETIC ACID, CADMIUM ION, Phosphoribosyl-AMP cyclohydrolase | Authors: | Sivaraman, J, Myers, R.S, Boju, L, Sulea, T, Cygler, M, Davisson, V.J, Schrag, J.D, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) | Deposit date: | 2005-05-17 | Release date: | 2005-08-30 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal Structure of Methanobacterium thermoautotrophicum Phosphoribosyl-AMP Cyclohydrolase HisI. Biochemistry, 44, 2005
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5JYO
| Allosteric inhibition of Kidney Isoform of Glutaminase | Descriptor: | 2-(pyridin-2-yl)-N-(5-{4-[6-({[3-(trifluoromethoxy)phenyl]acetyl}amino)pyridazin-3-yl]butyl}-1,3,4-thiadiazol-2-yl)acetamide, Glutaminase kidney isoform, mitochondrial | Authors: | Sivaraman, J, Jayaraman, S. | Deposit date: | 2016-05-15 | Release date: | 2016-08-03 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.098 Å) | Cite: | Structural basis for exploring the allosteric inhibition of human kidney type glutaminase. Oncotarget, 7, 2016
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5DIN
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3LCV
| Crystal Structure of Antibiotic related Methyltransferase | Descriptor: | S-ADENOSYLMETHIONINE, Sisomicin-gentamicin resistance methylase Sgm | Authors: | Sivaraman, J, Husain, N. | Deposit date: | 2010-01-11 | Release date: | 2010-06-02 | Last modified: | 2024-10-30 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis for the methylation of G1405 in 16S rRNA by aminoglycoside resistance methyltransferase Sgm from an antibiotic producer: a diversity of active sites in m7G methyltransferases. Nucleic Acids Res., 2010
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3LCU
| Crystal Structure of Antibiotic related Methyltransferase | Descriptor: | S-ADENOSYL-L-HOMOCYSTEINE, Sisomicin-gentamicin resistance methylase Sgm | Authors: | Sivaraman, J, Husain, N. | Deposit date: | 2010-01-11 | Release date: | 2010-06-02 | Last modified: | 2024-10-30 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural basis for the methylation of G1405 in 16S rRNA by aminoglycoside resistance methyltransferase Sgm from an antibiotic producer: a diversity of active sites in m7G methyltransferases. Nucleic Acids Res., 2010
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2R66
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2R68
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2R60
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5IAO
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6K2C
| Extended Hect domain of UBE3C E3 Ligase | Descriptor: | Ubiquitin-protein ligase E3C | Authors: | Sivaraman, J, Singh, S. | Deposit date: | 2019-05-14 | Release date: | 2020-03-04 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.703 Å) | Cite: | Crystal structure of HECT domain of UBE3C E3 ligase and its ubiquitination activity. Biochem.J., 477, 2020
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6JX5
| Hect domain of AREL1 | Descriptor: | Apoptosis-resistant E3 ubiquitin protein ligase 1 | Authors: | Sivaraman, J, Singh, S, Ng, J, Nayak, D. | Deposit date: | 2019-04-22 | Release date: | 2019-12-04 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.402 Å) | Cite: | Structural insights into a HECT-type E3 ligase AREL1 and its ubiquitination activitiesin vitro. J.Biol.Chem., 294, 2019
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6JX6
| Tetrameric form of Smac | Descriptor: | Diablo homolog, mitochondrial | Authors: | Sivaraman, J, Singh, S, Ng, J, Nayak, D. | Deposit date: | 2019-04-22 | Release date: | 2019-12-04 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.805 Å) | Cite: | Structural insights into a HECT-type E3 ligase AREL1 and its ubiquitination activitiesin vitro. J.Biol.Chem., 294, 2019
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1KSK
| STRUCTURE OF RSUA | Descriptor: | RIBOSOMAL SMALL SUBUNIT PSEUDOURIDINE SYNTHASE A, URACIL | Authors: | Sivaraman, J, Sauve, V, Larocque, R, Stura, E.A, Schrag, J.D, Cygler, M, Matte, A. | Deposit date: | 2002-01-13 | Release date: | 2002-04-24 | Last modified: | 2018-01-31 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of the 16S rRNA pseudouridine synthase RsuA bound to uracil and UMP. Nat.Struct.Biol., 9, 2002
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1IJI
| Crystal Structure of L-Histidinol Phosphate Aminotransferase with PLP | Descriptor: | Histidinol Phosphate Aminotransferase, PYRIDOXAL-5'-PHOSPHATE | Authors: | Sivaraman, J, Li, Y, Larocque, R, Schrag, J.D, Cygler, M, Matte, A. | Deposit date: | 2001-04-26 | Release date: | 2001-08-29 | Last modified: | 2017-10-04 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of histidinol phosphate aminotransferase (HisC) from Escherichia coli, and its covalent complex with pyridoxal-5'-phosphate and l-histidinol phosphate. J.Mol.Biol., 311, 2001
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1KSL
| STRUCTURE OF RSUA | Descriptor: | RIBOSOMAL SMALL SUBUNIT PSEUDOURIDINE SYNTHASE A, URACIL | Authors: | Sivaraman, J, Sauve, V, Larocque, R, Stura, E.A, Schrag, J.D, Cygler, M, Matte, A, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) | Deposit date: | 2002-01-13 | Release date: | 2002-04-24 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure of the 16S rRNA pseudouridine synthase RsuA bound to uracil and UMP. Nat.Struct.Biol., 9, 2002
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1KSV
| STRUCTURE OF RSUA | Descriptor: | RIBOSOMAL SMALL SUBUNIT PSEUDOURIDINE SYNTHASE A, URIDINE-5'-MONOPHOSPHATE | Authors: | Sivaraman, J, Sauve, V, Larocque, R, Stura, E.A, Schrag, J.D, Cygler, M, Matte, A. | Deposit date: | 2002-01-14 | Release date: | 2002-04-24 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Structure of the 16S rRNA pseudouridine synthase RsuA bound to uracil and UMP. Nat.Struct.Biol., 9, 2002
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1FG7
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1FG3
| CRYSTAL STRUCTURE OF L-HISTIDINOL PHOSPHATE AMINOTRANSFERASE COMPLEXED WITH L-HISTIDINOL | Descriptor: | HISTIDINOL PHOSPHATE AMINOTRANSFERASE, PHOSPHORIC ACID MONO-[2-AMINO-3-(3H-IMIDAZOL-4-YL)-PROPYL]ESTER, PYRIDOXAL-5'-PHOSPHATE | Authors: | Sivaraman, J, Cygler, M. | Deposit date: | 2000-07-27 | Release date: | 2001-08-22 | Last modified: | 2017-10-04 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of histidinol phosphate aminotransferase (HisC) from Escherichia coli, and its covalent complex with pyridoxal-5'-phosphate and l-histidinol phosphate. J.Mol.Biol., 311, 2001
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1PS7
| Crystal structure of E.coli PdxA | Descriptor: | 4-hydroxythreonine-4-phosphate dehydrogenase, ZINC ION | Authors: | Sivaraman, J, Li, Y, Banks, J, Cane, D.E, Matte, A, Cygler, M. | Deposit date: | 2003-06-20 | Release date: | 2003-11-04 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.47 Å) | Cite: | Crystal Structure of Escherichia coli PdxA, an Enzyme Involved in the Pyridoxal Phosphate Biosynthesis Pathway J.Biol.Chem., 278, 2003
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1DEU
| CRYSTAL STRUCTURE OF HUMAN PROCATHEPSIN X: A CYSTEINE PROTEASE WITH THE PROREGION COVALENTLY LINKED TO THE ACTIVE SITE CYSTEINE | Descriptor: | PROCATHEPSIN X | Authors: | Sivaraman, J, Nagler, D.K, Zhang, R, Menard, R, Cygler, M. | Deposit date: | 1999-11-15 | Release date: | 2000-02-18 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structure of human procathepsin X: a cysteine protease with the proregion covalently linked to the active site cysteine. J.Mol.Biol., 295, 2000
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1PS6
| Crystal structure of E.coli PdxA | Descriptor: | 4-HYDROXY-L-THREONINE-5-MONOPHOSPHATE, 4-hydroxythreonine-4-phosphate dehydrogenase, ZINC ION | Authors: | Sivaraman, J, Li, Y, Banks, J, Cane, D.E, Matte, A, Cygler, M. | Deposit date: | 2003-06-20 | Release date: | 2003-11-04 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Crystal Structure of Escherichia coli PdxA, an Enzyme Involved in the Pyridoxal Phosphate Biosynthesis Pathway J.Biol.Chem., 278, 2003
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1PRZ
| Crystal structure of pseudouridine synthase RluD catalytic module | Descriptor: | Ribosomal large subunit pseudouridine synthase D | Authors: | Sivaraman, J, Iannuzzi, P, Cygler, M, Matte, A, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) | Deposit date: | 2003-06-20 | Release date: | 2003-11-04 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of the RluD pseudouridine Synthase catalytic module, an
enzyme that modifies 23S rRNA and is essential for normal cell growth of Escherichia coli J.Mol.Biol., 335, 2003
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1PTM
| Crystal structure of E.coli PdxA | Descriptor: | 4-hydroxythreonine-4-phosphate dehydrogenase, PHOSPHATE ION, ZINC ION | Authors: | Sivaraman, J, Li, Y, Banks, J, Cane, D.E, Matte, A, Cygler, M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) | Deposit date: | 2003-06-23 | Release date: | 2003-11-04 | Last modified: | 2024-10-30 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Crystal Structure of Escherichia coli PdxA, an Enzyme Involved in the Pyridoxal Phosphate Biosynthesis Pathway J.Biol.Chem., 278, 2003
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1MC3
| CRYSTAL STRUCTURE OF RFFH | Descriptor: | GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE, MAGNESIUM ION, THYMIDINE-5'-TRIPHOSPHATE | Authors: | Sivaraman, J, Sauve, V, Matte, A, Cygler, M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) | Deposit date: | 2002-08-05 | Release date: | 2002-11-20 | Last modified: | 2024-10-30 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal Structure of Escherichia coli Glucose-1-Phosphate Thymidylyltransferase (RffH) Complexed with dTTP and Mg2+ J.BIOL.CHEM., 277, 2002
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