3MK5
 
 | | Crystal structure of 3,4-dihydroxy-2-butanone 4-phosphate synthase domain from Mycobacterium tuberculosis with sulfate and zinc at pH 4.00 | | Descriptor: | 3,4-dihydroxy-2-butanone 4-phosphate synthase, SULFATE ION, ZINC ION | | Authors: | Singh, M, Karthikeyan, S. | | Deposit date: | 2010-04-14 | | Release date: | 2011-02-23 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.06 Å) | | Cite: | Structural basis for pH dependent monomer-dimer transition of 3,4-dihydroxy 2-butanone-4-phosphate synthase domain from Mycobacterium tuberculosis
J.Struct.Biol., 174, 2011
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3MGZ
 | | Crystal structure of DHBPS domain of bi-functional DHBPS/GTP cyclohydrolase II from Mycobacterium tuberculosis at pH 4.0 | | Descriptor: | 3,4-dihydroxy-2-butanone 4-phosphate synthase, SULFATE ION | | Authors: | Singh, M, Kumar, P, Karthikeyan, S. | | Deposit date: | 2010-04-07 | | Release date: | 2011-02-23 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.07 Å) | | Cite: | Structural basis for pH dependent monomer-dimer transition of 3,4-dihydroxy 2-butanone-4-phosphate synthase domain from Mycobacterium tuberculosis
J.Struct.Biol., 174, 2011
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3MIO
 | | Crystal structure of 3,4-dihydroxy-2-butanone 4-phosphate synthase domain from Mycobacterium tuberculosis at pH 6.00 | | Descriptor: | 3,4-dihydroxy-2-butanone 4-phosphate synthase, GLYCEROL, PHOSPHATE ION, ... | | Authors: | Singh, M, Karthikeyan, S. | | Deposit date: | 2010-04-11 | | Release date: | 2011-02-23 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural basis for pH dependent monomer-dimer transition of 3,4-dihydroxy 2-butanone-4-phosphate synthase domain from Mycobacterium tuberculosis
J.Struct.Biol., 174, 2011
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2GRC
 | | 1.5 A structure of bromodomain from human BRG1 protein, a central ATPase of SWI/SNF remodeling complex | | Descriptor: | Probable global transcription activator SNF2L4 | | Authors: | Singh, M, Popowicz, G.M, Krajewski, M, Holak, T.A. | | Deposit date: | 2006-04-24 | | Release date: | 2007-05-08 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Structural ramification for acetyl-lysine recognition by the bromodomain of human BRG1 protein, a central ATPase of the SWI/SNF remodeling complex.
Chembiochem, 8, 2007
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4KM6
 | | Human folate receptor alpha (FOLR1) at acidic pH, orthorhombic form | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Folate receptor alpha | | Authors: | Singh, M, Dann III, C.E. | | Deposit date: | 2013-05-08 | | Release date: | 2013-08-07 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Structures of human folate receptors reveal biological trafficking states and diversity in folate and antifolate recognition.
Proc.Natl.Acad.Sci.USA, 110, 2013
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2LSL
 | | Solution structure of the C-terminal domain of Tetrahymena telomerase protein p65 | | Descriptor: | Telomerase associated protein p65 | | Authors: | Singh, M, Wang, Z, Koo, B, Patel, A, Cascio, D, Collins, K, Feigon, J. | | Deposit date: | 2012-05-01 | | Release date: | 2012-06-20 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Structural Basis for Telomerase RNA Recognition and RNP Assembly by the Holoenzyme La Family Protein p65.
Mol.Cell, 47, 2012
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3EUD
 | | Structure of the CS domain of the essential H/ACA RNP assembly protein Shq1p | | Descriptor: | Protein SHQ1 | | Authors: | Singh, M, Cascio, D, Gonzales, F.A, Heckmann, N, Chanfreau, G, Feigon, J. | | Deposit date: | 2008-10-09 | | Release date: | 2008-11-18 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structure and Functional Studies of the CS Domain of the Essential H/ACA Ribonucleoparticle Assembly Protein SHQ1.
J.Biol.Chem., 284, 2009
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2MNW
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4EYT
 | | Crystal structure of the C-terminal domain of Tetrahymena telomerase protein p65 | | Descriptor: | SULFATE ION, Telomerase associated protein p65 | | Authors: | Singh, M, Wang, Z, Koo, B.-K, Patel, A, Cascio, D, Collins, K, Feigon, J. | | Deposit date: | 2012-05-01 | | Release date: | 2012-06-20 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural Basis for Telomerase RNA Recognition and RNP Assembly by the Holoenzyme La Family Protein p65.
Mol.Cell, 47, 2012
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4ERD
 | | Crystal structure of the C-terminal domain of Tetrahymena telomerase protein p65 in complex with stem IV of telomerase RNA | | Descriptor: | 5'-R(P*GP*GP*UP*CP*GP*AP*CP*AP*UP*CP*UP*UP*CP*GP*GP*AP*UP*GP*GP*AP*CP*C)-3', POTASSIUM ION, Telomerase associated protein p65 | | Authors: | Singh, M, Wang, Z, Koo, B.-K, Patel, A, Cascio, D, Collins, K, Feigon, J. | | Deposit date: | 2012-04-19 | | Release date: | 2012-06-20 | | Last modified: | 2017-11-15 | | Method: | X-RAY DIFFRACTION (2.589 Å) | | Cite: | Structural Basis for Telomerase RNA Recognition and RNP Assembly by the Holoenzyme La Family Protein p65.
Mol.Cell, 47, 2012
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4I14
 | | Crystal Structure of Mtb-ribA2 (Rv1415) | | Descriptor: | Riboflavin biosynthesis protein RibBA, SULFATE ION, ZINC ION | | Authors: | Singh, M, Kumar, P, Yadav, S, Gautam, R, Sharma, N, Karthikeyan, S. | | Deposit date: | 2012-11-20 | | Release date: | 2013-08-28 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | The crystal structure reveals the molecular mechanism of bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II (Rv1415) from Mycobacterium tuberculosis
Acta Crystallogr.,Sect.D, 69, 2013
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4PBD
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4PCK
 | | Crystal structure of the P22S mutant of N-terminal CS domain of human Shq1 | | Descriptor: | GLYCEROL, Protein SHQ1 homolog | | Authors: | Singh, M, Wang, Z, Cascio, D, Feigon, J. | | Deposit date: | 2014-04-15 | | Release date: | 2015-01-14 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.401 Å) | | Cite: | Structure and Interactions of the CS Domain of Human H/ACA RNP Assembly Protein Shq1.
J.Mol.Biol., 427, 2015
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7WU8
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4G1P
 | | Structural and Mechanistic Basis of Substrate Recognition by Novel Di-peptidase Dug1p From Saccharomyces cerevisiae | | Descriptor: | CYSTEINE, Cys-Gly metallodipeptidase DUG1, GLYCINE, ... | | Authors: | Singh, A.K, Singh, M, Pandya, V.K, Singh, V, Mittal, M, Kumaran, S. | | Deposit date: | 2012-07-11 | | Release date: | 2013-07-17 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.547 Å) | | Cite: | Structural and Mechanistic Basis of Substrate Recognition by Novel Di-peptidase Dug1p From Saccromyces cerevesiae
To be published
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8GAP
 | | Structure of LARP7 protein p65-telomerase RNA complex in telomerase | | Descriptor: | Telomerase La-related protein p65, Telomerase RNA, Telomerase associated protein p50, ... | | Authors: | Wang, Y, He, Y, Wang, Y, Yang, Y, Singh, M, Eichhorn, C.D, Zhou, Z.H, Feigon, J. | | Deposit date: | 2023-02-23 | | Release date: | 2023-06-28 | | Last modified: | 2024-06-19 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Structure of LARP7 Protein p65-telomerase RNA Complex in Telomerase Revealed by Cryo-EM and NMR.
J.Mol.Biol., 435, 2023
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2WBC
 | | REFINED CRYSTAL STRUCTURE (2.3 ANGSTROM) OF A WINGED BEAN CHYMOTRYPSIN INHIBITOR AND LOCATION OF ITS SECOND REACTIVE SITE | | Descriptor: | CHYMOTRYPSIN INHIBITOR | | Authors: | Dattagupta, J.K, Podder, A, Chakrabarti, C, Sen, U, Mukhopadhyay, D, Dutta, S.K, Singh, M. | | Deposit date: | 1997-11-26 | | Release date: | 1998-02-25 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Refined crystal structure (2.3 A) of a double-headed winged bean alpha-chymotrypsin inhibitor and location of its second reactive site.
Proteins, 35, 1999
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7YL9
 | | Cryo-EM structure of complete transmembrane channel E289A mutant Vibrio cholerae Cytolysin | | Descriptor: | Hemolysin | | Authors: | Mondal, A.K, Sengupta, N, Singh, M, Biswas, R, Lata, K, Lahiri, I, Dutta, S, Chattopadhyay, K. | | Deposit date: | 2022-07-25 | | Release date: | 2022-08-31 | | Last modified: | 2024-10-16 | | Method: | ELECTRON MICROSCOPY (4.7 Å) | | Cite: | Cryo-EM structure of complete transmembrane channel E289A mutant Vibrio cholerae Cytolysin
J.Biol.Chem.
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1JEK
 | | Visna TM CORE STRUCTURE | | Descriptor: | ENV POLYPROTEIN | | Authors: | Malashkevich, V.N, Singh, M, Kim, P.S. | | Deposit date: | 2001-06-18 | | Release date: | 2001-07-25 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | The trimer-of-hairpins motif in membrane fusion: Visna virus.
Proc.Natl.Acad.Sci.USA, 98, 2001
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1G2C
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6KML
 | | 2.09 Angstrom resolution crystal structure of tetrameric HigBA toxin-antitoxin complex from E.coli | | Descriptor: | Antitoxin HigA, mRNA interferase toxin HigB | | Authors: | Jadhav, P, Sinha, V.K, Rothweiler, U, Singh, M. | | Deposit date: | 2019-07-31 | | Release date: | 2020-11-18 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.095 Å) | | Cite: | 2.09 angstrom Resolution structure of E. coli HigBA toxin-antitoxin complex reveals an ordered DNA-binding domain and intrinsic dynamics in antitoxin.
Biochem.J., 477, 2020
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6KMQ
 | | 2.3 Angstrom resolution structure of dimeric HigBA toxin-antitoxin complex from E. coli | | Descriptor: | Antitoxin HigA, mRNA interferase toxin HigB | | Authors: | Jadhav, P, Sinha, V.K, Rothweiler, U, Singh, M. | | Deposit date: | 2019-07-31 | | Release date: | 2020-11-18 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | 2.09 angstrom Resolution structure of E. coli HigBA toxin-antitoxin complex reveals an ordered DNA-binding domain and intrinsic dynamics in antitoxin.
Biochem.J., 477, 2020
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1Y25
 | | structure of mycobacterial thiol peroxidase Tpx | | Descriptor: | ACETATE ION, Probable thiol peroxidase | | Authors: | Stehr, M, Hoffmann, B, Jger, T, Singh, M, Hecht, H.J. | | Deposit date: | 2004-11-20 | | Release date: | 2005-11-20 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structure of the inactive variant C60S of Mycobacterium tuberculosis thiol peroxidase
Acta Crystallogr.,Sect.D, 62, 2006
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3MK3
 | | Crystal structure of Lumazine synthase from Salmonella typhimurium LT2 | | Descriptor: | 6,7-dimethyl-8-ribityllumazine synthase, SULFATE ION | | Authors: | Kumar, P, Singh, M, Karthikeyan, S. | | Deposit date: | 2010-04-14 | | Release date: | 2011-02-02 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (3.569 Å) | | Cite: | Crystal structure analysis of icosahedral lumazine synthase from Salmonella typhimurium, an antibacterial drug target.
Acta Crystallogr.,Sect.D, 67, 2011
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3NQ4
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