2P4N
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5KG8
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1MKJ
| Human Kinesin Motor Domain With Docked Neck Linker | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, KINESIN HEAVY CHAIN, MAGNESIUM ION, ... | Authors: | Sindelar, C.V, Budny, M.J, Rice, S, Naber, N, Fletterick, R, Cooke, R. | Deposit date: | 2002-08-29 | Release date: | 2002-10-30 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Two conformations in the human kinesin power stroke defined by X-ray crystallography and EPR spectroscopy. Nat.Struct.Biol., 9, 2002
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3DCO
| Drosophila NOD (3DC4) and Bovine Tubulin (1JFF) Docked into the 11-Angstrom Cryo-EM Map of Nucleotide-Free NOD Complexed to the Microtubule | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Bovine Alpha Tubulin, Bovine Beta Tubulin, ... | Authors: | Sindelar, C.V, Cochran, J.C, Kull, F.J. | Deposit date: | 2008-06-04 | Release date: | 2009-02-10 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (11 Å) | Cite: | ATPase cycle of the nonmotile kinesin NOD allows microtubule end tracking and drives chromosome movement. Cell(Cambridge,Mass.), 136, 2009
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6PWB
| Rigid body fitting of flagellin FlaB, and flagellar coiling proteins, FcpA and FcpB, into a 10 Angstrom structure of the asymmetric flagellar filament purified from Leptospira biflexa Patoc WT cells resolved via subtomogram averaging | Descriptor: | Flagellar coiling protein A (FcpA), Flagellar coiling protein B (FcpB), Flagellin B1 (FlaB1) | Authors: | Gibson, K.H, Sindelar, C.V, Trajtenberg, F, Buschiazzo, A, San Martin, F, Mechaly, A. | Deposit date: | 2019-07-22 | Release date: | 2020-03-25 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (9.83 Å) | Cite: | An asymmetric sheath controls flagellar supercoiling and motility in the leptospira spirochete. Elife, 9, 2020
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7T7X
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7T7V
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8UZ1
| Straight actin filament from Arp2/3 branch junction sample (ADP-BeFx) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Chavali, S.S, Chou, S.Z, Sindelar, C.V. | Deposit date: | 2023-11-14 | Release date: | 2024-01-31 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Cryo-EM structures reveal how phosphate release from Arp3 weakens actin filament branches formed by Arp2/3 complex. Nat Commun, 15, 2024
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8UXW
| Arp2/3 branch junction complex, ADP state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... | Authors: | Chavali, S.S, Chou, S.Z, Sindelar, C.V. | Deposit date: | 2023-11-11 | Release date: | 2024-01-31 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Cryo-EM structures reveal how phosphate release from Arp3 weakens actin filament branches formed by Arp2/3 complex. Nat Commun, 15, 2024
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8UXX
| Arp2/3 branch junction complex, BeFx state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... | Authors: | Chavali, S.S, Chou, S.Z, Sindelar, C.V. | Deposit date: | 2023-11-11 | Release date: | 2024-01-31 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Cryo-EM structures reveal how phosphate release from Arp3 weakens actin filament branches formed by Arp2/3 complex. Nat Commun, 15, 2024
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8UZ0
| Straight actin filament from Arp2/3 branch junction sample (ADP) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Chavali, S.S, Chou, S.Z, Sindelar, C.V. | Deposit date: | 2023-11-14 | Release date: | 2024-01-31 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Cryo-EM structures reveal how phosphate release from Arp3 weakens actin filament branches formed by Arp2/3 complex. Nat Commun, 15, 2024
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7T7R
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7T7C
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7T81
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6MTI
| Synaptotagmin-1 C2A, C2B domains and SNARE-pin proteins (5CCI) individually docked into Cryo-EM map of C2AB-SNARE complexes helically organized on lipid nanotube surface in presence of Mg2+ | Descriptor: | MAGNESIUM ION, Synaptosomal-associated protein 25, Synaptotagmin-1, ... | Authors: | Grushin, K, Wang, J, Coleman, J, Rothman, J, Sindelar, C, Krishnakumar, S. | Deposit date: | 2018-10-19 | Release date: | 2019-04-24 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (10.4 Å) | Cite: | Structural basis for the clamping and Ca2+activation of SNARE-mediated fusion by synaptotagmin. Nat Commun, 10, 2019
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2XRP
| Human Doublecortin N-DC Repeat (1MJD) and Mammalian Tubulin (1JFF and 3HKE) Docked into the 8-Angstrom Cryo-EM Map of Doublecortin- Stabilised Microtubules | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, NEURONAL MIGRATION PROTEIN DOUBLECORTIN, ... | Authors: | Fourniol, F.J, Sindelar, C.V, Amigues, B, Clare, D.K, Thomas, G, Perderiset, M, Francis, F, Houdusse, A, Moores, C.A. | Deposit date: | 2010-09-18 | Release date: | 2010-11-24 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (8.2 Å) | Cite: | Template-Free 13-Protofilament Microtubule-Map Assembly Visualized at 8 A Resolution. J.Cell Biol., 191, 2010
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6WVL
| Low curvature lateral interaction within a 13-protofilament, Taxol stabilized microtubule | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Debs, G.E, Cha, M, Huehn, A.R, Sindelar, C.V. | Deposit date: | 2020-05-06 | Release date: | 2020-05-20 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Dynamic and asymmetric fluctuations in the microtubule wall captured by high-resolution cryoelectron microscopy. Proc.Natl.Acad.Sci.USA, 117, 2020
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6WVM
| High curvature lateral interaction within a 13-protofilament, Taxol stabilized microtubule | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Debs, G.E, Cha, M, Huehn, A.R, Sindelar, C.V. | Deposit date: | 2020-05-06 | Release date: | 2020-05-20 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Dynamic and asymmetric fluctuations in the microtubule wall captured by high-resolution cryoelectron microscopy. Proc.Natl.Acad.Sci.USA, 117, 2020
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3J8Y
| High-resolution structure of ATP analog-bound kinesin on microtubules | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Shang, Z, Zhou, K, Xu, C, Csencsits, R, Cochran, J.C, Sindelar, C.V. | Deposit date: | 2014-11-20 | Release date: | 2014-12-10 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (5 Å) | Cite: | High-resolution structures of kinesin on microtubules provide a basis for nucleotide-gated force-generation. Elife, 3, 2014
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3J8X
| High-resolution structure of no-nucleotide kinesin on microtubules | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-1 heavy chain, ... | Authors: | Shang, Z, Zhou, K, Xu, C, Csencsits, R, Cochran, J.C, Sindelar, C.V. | Deposit date: | 2014-11-20 | Release date: | 2014-12-10 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (5 Å) | Cite: | High-resolution structures of kinesin on microtubules provide a basis for nucleotide-gated force-generation. Elife, 3, 2014
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6C1D
| High-Resolution Cryo-EM Structures of Actin-bound Myosin States Reveal the Mechanism of Myosin Force Sensing | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Mentes, A, Huehn, A, Liu, X, Zwolak, A, Dominguez, R, Shuman, H, Ostap, E.M, Sindelar, C.V. | Deposit date: | 2018-01-04 | Release date: | 2018-01-31 | Last modified: | 2020-01-08 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | High-resolution cryo-EM structures of actin-bound myosin states reveal the mechanism of myosin force sensing. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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4AQV
| Model of human kinesin-5 motor domain (3HQD) and mammalian tubulin heterodimer (1JFF) docked into the 9.7-angstrom cryo-EM map of microtubule-bound kinesin-5 motor domain in the AMPPPNP state. | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, KINESIN-LIKE PROTEIN KIF11, ... | Authors: | Goulet, A, Behnke-Parks, W.M, Sindelar, C.V, Rosenfeld, S.S, Moores, C.A. | Deposit date: | 2012-04-19 | Release date: | 2012-11-21 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (9.7 Å) | Cite: | The Structural Basis of Force Generation by the Mitotic Motor Kinesin-5. J.Biol.Chem., 287, 2012
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6C1G
| High-Resolution Cryo-EM Structures of Actin-bound Myosin States Reveal the Mechanism of Myosin Force Sensing | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Mentes, A, Huehn, A, Liu, X, Zwolak, A, Dominguez, R, Shuman, H, Ostap, E.M, Sindelar, C.V. | Deposit date: | 2018-01-04 | Release date: | 2018-01-31 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | High-resolution cryo-EM structures of actin-bound myosin states reveal the mechanism of myosin force sensing. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6C1H
| High-Resolution Cryo-EM Structures of Actin-bound Myosin States Reveal the Mechanism of Myosin Force Sensing | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Mentes, A, Huehn, A, Liu, X, Zwolak, A, Dominguez, R, Shuman, H, Ostap, E.M, Sindelar, C.V. | Deposit date: | 2018-01-04 | Release date: | 2018-01-31 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | High-resolution cryo-EM structures of actin-bound myosin states reveal the mechanism of myosin force sensing. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6D8C
| Cryo-EM structure of FLNaABD E254K bound to phalloidin-stabilized F-actin | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Iwamoto, D.V, Huehn, A.R, Simon, B, Huet-Calderwood, C, Baldassarre, M, Sindelar, C.V, Calderwood, D.A. | Deposit date: | 2018-04-26 | Release date: | 2018-09-19 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (3.54 Å) | Cite: | Structural basis of the filamin A actin-binding domain interaction with F-actin. Nat. Struct. Mol. Biol., 25, 2018
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