2AR9
| Crystal structure of a dimeric caspase-9 | 分子名称: | Caspase-9, D-MALATE | 著者 | Chao, Y, Shiozaki, E.N, Srinivassula, S.M, Rigotti, D.J, Fairman, R, Shi, Y. | 登録日 | 2005-08-19 | 公開日 | 2005-10-11 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Engineering a Dimeric Caspase-9: A Re-Evaluation of the Induced Proximity Model for Caspase Activation PLOS BIOL., 3, 2005
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4Y6K
| Complex structure of presenilin homologue PSH bound to an inhibitor | 分子名称: | N-{(2R,4S,5S)-2-benzyl-5-[(tert-butoxycarbonyl)amino]-4-hydroxy-6-phenylhexanoyl}-L-leucyl-L-phenylalaninamide, Uncharacterized protein PSH | 著者 | Dang, S, Wu, S, Wang, J, Shi, Y. | 登録日 | 2015-02-13 | 公開日 | 2015-03-18 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.855 Å) | 主引用文献 | Cleavage of amyloid precursor protein by an archaeal presenilin homologue PSH Proc.Natl.Acad.Sci.USA, 112, 2015
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2HV6
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2HV7
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2OSG
| Solution Structure and Binding Property of the Domain-swapped Dimer of ZO2PDZ2 | 分子名称: | Tight junction protein ZO-2 | 著者 | Wu, J.W, Yang, Y.S, Zhang, J.H, Ji, P, Wu, J.H, Shi, Y.Y. | 登録日 | 2007-02-05 | 公開日 | 2007-09-25 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Domain-swapped Dimerization of the Second PDZ Domain of ZO2 May Provide a Structural Basis for the Polymerization of Claudins J.Biol.Chem., 282, 2007
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2IE3
| Structure of the Protein Phosphatase 2A Core Enzyme Bound to Tumor-inducing Toxins | 分子名称: | MANGANESE (II) ION, Protein Phosphatase 2, regulatory subunit A (PR 65), ... | 著者 | Xing, Y, Xu, Y, Chen, Y, Jeffrey, P.D, Chao, Y, Shi, Y. | 登録日 | 2006-09-17 | 公開日 | 2006-11-07 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structure of Protein Phosphatase 2A Core Enzyme Bound to Tumor-Inducing Toxins Cell(Cambridge,Mass.), 127, 2006
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2IE4
| Structure of the Protein Phosphatase 2A Core Enzyme Bound to okadaic acid | 分子名称: | MANGANESE (II) ION, OKADAIC ACID, Protein Phosphatase 2, ... | 著者 | Xing, Y, Xu, Y, Chen, Y, Jeffrey, P.D, Chao, Y, Shi, Y. | 登録日 | 2006-09-17 | 公開日 | 2006-11-07 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structure of Protein Phosphatase 2A Core Enzyme Bound to Tumor-Inducing Toxins Cell(Cambridge,Mass.), 127, 2006
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6XYO
| Multiple system atrophy Type I alpha-synuclein filament | 分子名称: | Alpha-synuclein | 著者 | Schweighauser, M, Shi, Y, Tarutani, A, Kametani, F, Murzin, A.G, Ghetti, B, Matsubara, T, Tomita, T, Ando, T, Hasegawa, K, Murayama, S, Yoshida, M, Hasegawa, M, Scheres, S.H.W, Goedert, M. | 登録日 | 2020-01-30 | 公開日 | 2020-02-12 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Structures of alpha-synuclein filaments from multiple system atrophy. Nature, 585, 2020
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6XYP
| Multiple system atrophy Type II-1 alpha-synuclein filament | 分子名称: | Alpha-synuclein | 著者 | Schweighauser, M, Shi, Y, Tarutani, A, Kametani, F, Murzin, A.G, Ghetti, B, Matsubara, T, Tomita, T, Ando, T, Hasegawa, K, Murayama, S, Yoshida, M, Hasegawa, M, Scheres, S.H.W, Goedert, M. | 登録日 | 2020-01-30 | 公開日 | 2020-02-12 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.29 Å) | 主引用文献 | Structures of alpha-synuclein filaments from multiple system atrophy. Nature, 585, 2020
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2F7X
| Protein Kinase A bound to (S)-2-(1H-Indol-3-yl)-1-[5-((E)-2-pyridin-4-yl-vinyl)-pyridin-3-yloxymethyl]-ethylamine | 分子名称: | (1S)-2-(1H-INDOL-3-YL)-1-[({5-[(E)-2-PYRIDIN-4-YLVINYL]PYRIDIN-3-YL}OXY)METHYL]ETHYLAMINE, PKI, inhibitory peptide, ... | 著者 | Li, Q, Li, T, Zhu, G.D, Gong, J, Claibone, A, Dalton, C, Luo, Y, Johnson, E.F, Shi, Y, Liu, X, Klinghofer, V, Bauch, J.L, Marsh, K.C, Bouska, J.J, Arries, S, De Jong, R, Oltersdorf, T, Stoll, V.S, Jakob, C.G, Rosenberg, S.H, Giranda, V.L. | 登録日 | 2005-12-01 | 公開日 | 2006-06-27 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Discovery of trans-3,4'-bispyridinylethylenes as potent and novel inhibitors of protein kinase B (PKB/Akt) for the treatment of cancer: Synthesis and biological evaluation. Bioorg.Med.Chem.Lett., 16, 2006
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2F1S
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2F7Z
| Protein Kinase A bound to (R)-1-(1H-Indol-3-ylmethyl)-2-(2-pyridin-4-yl-[1,7]naphtyridin-5-yloxy)-ehylamine | 分子名称: | (1S)-1-(1H-INDOL-3-YLMETHYL)-2-(2-PYRIDIN-4-YL-[1,7]NAPHTYRIDIN-5-YLOXY)-EHYLAMINE, PKI, inhibitory peptide, ... | 著者 | Li, Q, Woods, K.W, Thomas, S, Zhu, G.D, Packard, G, Fisher, J, Li, T, Gong, J, Dinges, J, Song, X, Abrams, J, Luo, Y, Johnson, E.F, Shi, Y, Liu, X, Klinghofer, V, Des Jong, R, Oltersdorf, T, Stoll, V.S, Jakob, C.G, Rosenberg, S.H, Giranda, V.L. | 登録日 | 2005-12-01 | 公開日 | 2006-06-27 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Synthesis and structure-activity relationship of 3,4'-bispyridinylethylenes: discovery of a potent 3-isoquinolinylpyridine inhibitor of protein kinase B (PKB/Akt) for the treatment of cancer. Bioorg.Med.Chem.Lett., 16, 2006
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4M9S
| crystal structure of CED-4 bound CED-3 fragment | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CED-3 fragment, Cell death protein 4, ... | 著者 | Huang, W.J, Jinag, T.Y, Choi, W.Y, Wang, J.W, Shi, Y.G. | 登録日 | 2013-08-15 | 公開日 | 2013-10-23 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (3.207 Å) | 主引用文献 | Mechanistic insights into CED-4-mediated activation of CED-3. Genes Dev., 27, 2013
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2AIN
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2AX5
| Solution Structure of Urm1 from Saccharomyces Cerevisiae | 分子名称: | Hypothetical 11.0 kDa protein in FAA3-MAS3 intergenic region | 著者 | Xu, J, Huang, H, Zhang, J, Wu, J, Shi, Y. | 登録日 | 2005-09-03 | 公開日 | 2006-06-27 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of Urm1 and its implications for the origin of protein modifiers. Proc.Natl.Acad.Sci.Usa, 103, 2006
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1JD6
| Crystal Structure of DIAP1-BIR2/Hid Complex | 分子名称: | APOPTOSIS 1 INHIBITOR, ZINC ION, head involution defective protein | 著者 | Wu, J.W, Cocina, A.E, Chai, J, Hay, B.A, Shi, Y. | 登録日 | 2001-06-12 | 公開日 | 2001-12-05 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural analysis of a functional DIAP1 fragment bound to grim and hid peptides. Mol.Cell, 8, 2001
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1JD4
| Crystal Structure of DIAP1-BIR2 | 分子名称: | APOPTOSIS 1 INHIBITOR, ZINC ION | 著者 | Wu, J.W, Cocina, A.E, Chai, J, Hay, B.A, Shi, Y. | 登録日 | 2001-06-12 | 公開日 | 2001-12-05 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural analysis of a functional DIAP1 fragment bound to grim and hid peptides. Mol.Cell, 8, 2001
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1JD5
| Crystal Structure of DIAP1-BIR2/GRIM | 分子名称: | APOPTOSIS 1 INHIBITOR, ZINC ION, cell death protein GRIM | 著者 | Wu, J.W, Cocina, A.E, Chai, J, Hay, B.A, Shi, Y. | 登録日 | 2001-06-12 | 公開日 | 2001-12-05 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural analysis of a functional DIAP1 fragment bound to grim and hid peptides. Mol.Cell, 8, 2001
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4YY0
| The structure of hemagglutinin from a H6N1 influenza virus (A/chicken/Taiwan/A2837/2013) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, HA1, HA2 | 著者 | Wang, F, Qi, J, Bi, Y, Zhang, W, Wang, M, Wang, M, Liu, J, Yan, J, Shi, Y, Gao, G.F. | 登録日 | 2015-03-23 | 公開日 | 2016-03-23 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | 主引用文献 | Structure of hemagglutinin from a H6N1 influenza virus (A/chicken/Taiwan/A2837/2013) To Be Published
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1K86
| Crystal structure of caspase-7 | 分子名称: | caspase-7 | 著者 | Chai, J, Wu, Q, Shiozaki, E, Srinivasa, S.M, Alnemri, E.S, Shi, Y. | 登録日 | 2001-10-23 | 公開日 | 2001-11-21 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal structure of a procaspase-7 zymogen: mechanisms of activation and substrate binding Cell(Cambridge,Mass.), 107, 2001
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1K88
| Crystal structure of procaspase-7 | 分子名称: | procaspase-7 | 著者 | Chai, J, Wu, Q, Shiozaki, E, Srinivasa, S.M, Alnemri, E.S, Shi, Y. | 登録日 | 2001-10-23 | 公開日 | 2001-11-21 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystal structure of a procaspase-7 zymogen: mechanisms of activation and substrate binding Cell(Cambridge,Mass.), 107, 2001
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5GJR
| An atomic structure of the human 26S proteasome | 分子名称: | 26S protease regulatory subunit 10B, 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, ... | 著者 | Huang, X.L, Luan, B, Wu, J.P, Shi, Y.G. | 登録日 | 2016-07-01 | 公開日 | 2016-09-07 | 最終更新日 | 2019-10-09 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | An atomic structure of the human 26S proteasome. Nat. Struct. Mol. Biol., 23, 2016
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7XKC
| Crystal structure of Daucus Carrot hypoglycemic peptide (DCHP) | 分子名称: | DCHP, SULFATE ION | 著者 | Guo, T, Ren, J.Q, Wang, L, Shi, Y.W, Feng, W. | 登録日 | 2022-04-19 | 公開日 | 2022-05-18 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.56 Å) | 主引用文献 | Characterization of a thermostable, protease-tolerant inhibitor of alpha-glycosidase from carrot: A potential oral additive for treatment of diabetes. Int.J.Biol.Macromol., 209, 2022
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3RES
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1MR1
| Crystal Structure of a Smad4-Ski Complex | 分子名称: | Mothers against decapentaplegic homolog 4, Ski oncogene, ZINC ION | 著者 | Wu, J.-W, Krawitz, A.R, Chai, J, Li, W, Zhang, F, Luo, K, Shi, Y. | 登録日 | 2002-09-17 | 公開日 | 2003-01-21 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Structural Mechanism of Smad4 Recognition by the Nuclear Oncoprotein Ski: Insights on Ski-mediated Repression of TGF-beta Signaling Cell(Cambridge,Mass.), 111, 2002
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