6BTP
 
 | | BMP1 complexed with a hydroxamate | | 分子名称: | (1R,3S,4S)-2-{(2R)-2-[2-(hydroxyamino)-2-oxoethyl]heptanoyl}-N-(3-methoxypyrazin-2-yl)-2-azabicyclo[2.2.1]heptane-3-carboxamide, Bone morphogenetic protein 1, THIOCYANATE ION, ... | | 著者 | Gampe, R, Shewchuk, L. | | 登録日 | 2017-12-07 | | 公開日 | 2018-08-08 | | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | | 主引用文献 | Reverse Hydroxamate Inhibitors of Bone Morphogenetic Protein 1.
ACS Med Chem Lett, 9, 2018
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6BTN
 | | BMP1 complexed with a reverse hydroxymate - compound 1 | | 分子名称: | (3S)-6-cyclohexyl-3-{3-[(dimethylamino)methyl]-1,2,4-oxadiazol-5-yl}-N-hydroxyhexanamide, 1,2-ETHANEDIOL, Bone morphogenetic protein 1, ... | | 著者 | Gampe, R, Shewchuk, L. | | 登録日 | 2017-12-07 | | 公開日 | 2018-08-08 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Reverse Hydroxamate Inhibitors of Bone Morphogenetic Protein 1.
ACS Med Chem Lett, 9, 2018
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6BSL
 | | BMP1 complexed with a reverse hydroxymate - compound 22 | | 分子名称: | 1,2-ETHANEDIOL, Bone morphogenetic protein 1, N-(2-ethoxy-4-{5-[({[(2R)-2-{(1R)-1-[formyl(hydroxy)amino]propyl}heptanoyl]amino}methyl)carbamoyl]furan-2-yl}benzene-1-carbonyl)-L-aspartic acid, ... | | 著者 | Gampe, R, Shewchuk, L. | | 登録日 | 2017-12-04 | | 公開日 | 2018-08-08 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Reverse Hydroxamate Inhibitors of Bone Morphogenetic Protein 1.
ACS Med Chem Lett, 9, 2018
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6BTQ
 | | BMP1 complexed with a hydroxamate - compound 2 | | 分子名称: | 1,2-ETHANEDIOL, Bone morphogenetic protein 1, N~2~-[(2H-1,3-benzodioxol-5-yl)methyl]-N-hydroxy-N~2~-[(4-methoxyphenyl)sulfonyl]-3-thiophen-2-yl-D-alaninamide, ... | | 著者 | Gampe, R, Shewchuk, L. | | 登録日 | 2017-12-07 | | 公開日 | 2018-08-08 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Reverse Hydroxamate Inhibitors of Bone Morphogenetic Protein 1.
ACS Med Chem Lett, 9, 2018
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3ETA
 | | Kinase domain of insulin receptor complexed with a pyrrolo pyridine inhibitor | | 分子名称: | 1-(3-{5-[4-(aminomethyl)phenyl]-1H-pyrrolo[2,3-b]pyridin-3-yl}phenyl)-3-(2-phenoxyphenyl)urea, insulin receptor, kinase domain | | 著者 | Patnaik, S, Stevens, K, Gerding, R, Deanda, F, Shotwell, B, Tang, J, Hamajima, T, Nakamura, H, Leesnitzer, A, Hassell, A, Shewchuk, L, Kumar, R, Lei, H, Chamberlain, S. | | 登録日 | 2008-10-07 | | 公開日 | 2009-05-26 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Discovery of 3,5-disubstituted-1H-pyrrolo[2,3-b]pyridines as potent inhibitors of the insulin-like growth factor-1 receptor (IGF-1R) tyrosine kinase.
Bioorg.Med.Chem.Lett., 19, 2009
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