1N75
| Crystal structure of Thermus thermophilus glutamyl-tRNA synthetase complexed with ATP. | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Glutamyl-tRNA synthetase, MAGNESIUM ION | 著者 | Sekine, S, Nureki, O, Dubois, D.Y, Bernier, S, Chenevert, R, Lapointe, J, Vassylyev, D.G, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2002-11-12 | 公開日 | 2003-02-25 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | ATP binding by glutamyl-tRNA synthetase is switched to the productive mode by tRNA binding EMBO J., 22, 2003
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1N77
| Crystal structure of Thermus thermophilus glutamyl-tRNA synthetase complexed with tRNA(Glu) and ATP. | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Glutamyl-tRNA synthetase, MAGNESIUM ION, ... | 著者 | Sekine, S, Nureki, O, Dubois, D.Y, Bernier, S, Chenevert, R, Lapointe, J, Vassylyev, D.G, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2002-11-13 | 公開日 | 2003-02-25 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | ATP binding by glutamyl-tRNA synthetase is switched to the productive mode by tRNA binding EMBO J., 22, 2003
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1N78
| Crystal structure of Thermus thermophilus glutamyl-tRNA synthetase complexed with tRNA(Glu) and glutamol-AMP. | 分子名称: | GLUTAMOL-AMP, Glutamyl-tRNA synthetase, MAGNESIUM ION, ... | 著者 | Sekine, S, Nureki, O, Dubois, D.Y, Bernier, S, Chenevert, R, Lapointe, J, Vassylyev, D.G, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2002-11-13 | 公開日 | 2003-02-25 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | ATP binding by glutamyl-tRNA synthetase is switched to the productive mode by tRNA binding EMBO J., 22, 2003
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2DXI
| 2.2 A crystal structure of glutamyl-tRNA synthetase from Thermus thermophilus complexed with tRNA(Glu), ATP, and L-glutamol | 分子名称: | (4S)-4-AMINO-5-HYDROXYPENTANOIC ACID, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Sekine, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2006-08-28 | 公開日 | 2006-10-31 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural bases of transfer RNA-dependent amino acid recognition and activation by glutamyl-tRNA synthetase Structure, 14, 2006
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2EPG
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1J09
| Crystal structure of Thermus thermophilus glutamyl-tRNA synthetase complexed with ATP and Glu | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, GLUTAMIC ACID, Glutamyl-tRNA synthetase, ... | 著者 | Sekine, S, Nureki, O, Dubois, D.Y, Bernier, S, Chenevert, R, Lapointe, J, Vassylyev, D.G, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2002-11-12 | 公開日 | 2003-02-25 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | ATP binding by glutamyl-tRNA synthetase is switched to the productive mode by tRNA binding EMBO J., 22, 2003
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1G59
| GLUTAMYL-TRNA SYNTHETASE COMPLEXED WITH TRNA(GLU). | 分子名称: | GLUTAMYL-TRNA SYNTHETASE, TRNA(GLU) | 著者 | Sekine, S, Nureki, O, Shimada, A, Vassylyev, D.G, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2000-10-31 | 公開日 | 2001-09-01 | 最終更新日 | 2023-08-02 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural basis for anticodon recognition by discriminating glutamyl-tRNA synthetase. Nat.Struct.Biol., 8, 2001
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2CV0
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2CUZ
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2CV2
| Glutamyl-tRNA synthetase from Thermus thermophilus in complex with tRNA(Glu) and an enzyme inhibitor, Glu-AMS | 分子名称: | CHLORIDE ION, MAGNESIUM ION, O5'-(L-GLUTAMYL-SULFAMOYL)-ADENOSINE, ... | 著者 | Sekine, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2005-05-31 | 公開日 | 2006-09-05 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.69 Å) | 主引用文献 | Structural bases of transfer RNA-dependent amino acid recognition and activation by glutamyl-tRNA synthetase Structure, 14, 2006
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2CV1
| Glutamyl-tRNA synthetase from Thermus thermophilus in complex with tRNA(Glu), ATP, and an analog of L-glutamate: a quaternary complex | 分子名称: | (4S)-4-AMINO-5-HYDROXYPENTANOIC ACID, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Sekine, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2005-05-31 | 公開日 | 2006-09-05 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | 主引用文献 | Glutamyl-tRNA synthetase from Thermus thermophilus in complex with tRNA(Glu), ATP, and an analog of L-glutamate: a quaternary complex To be Published
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2ZAU
| Crystal structure of an N-terminally truncated selenophosphate synthetase from Aquifex aeolicus | 分子名称: | PHOSPHATE ION, Selenide, water dikinase | 著者 | Sekine, S, Matsumoto, E, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2007-10-10 | 公開日 | 2008-06-17 | 最終更新日 | 2024-10-30 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure of an N-terminally truncated selenophosphate synthetase from Aquifex aeolicus Acta Crystallogr.,Sect.F, 64, 2008
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7YQ8
| Cryo-EM structure of human topoisomerase II beta in complex with DNA and etoposide | 分子名称: | (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol -5-yl 4,6-O-[(1R)-ethylidene]-beta-D-glucopyranoside, 50-mer DNA, DNA topoisomerase 2-beta, ... | 著者 | Naganuma, M, Ehara, H, Kim, D, Nakagawa, R, Cong, A, Bu, H, Jeong, J, Jang, J, Schellenberg, M.J, Bunch, H, Sekine, S. | 登録日 | 2022-08-05 | 公開日 | 2024-01-03 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | ERK2-topoisomerase II regulatory axis is important for gene activation in immediate early genes. Nat Commun, 14, 2023
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5X4Z
| RNA Polymerase II from Komagataella Pastoris (Type-1 crystal) | 分子名称: | DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, RNA polymerase II subunit, ... | 著者 | Ehara, H, Umehara, T, Sekine, S, Yokoyama, S. | 登録日 | 2017-02-14 | 公開日 | 2017-05-17 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (7.8 Å) | 主引用文献 | Crystal structure of RNA polymerase II from Komagataella pastoris Biochem. Biophys. Res. Commun., 487, 2017
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1UEB
| Crystal structure of translation elongation factor P from Thermus thermophilus HB8 | 分子名称: | elongation factor P | 著者 | Hanawa-Suetsugu, K, Sekine, S, Sakai, H, Hori-Takemoto, C, Terada, T, Kuramitsu, S, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2003-05-09 | 公開日 | 2004-05-25 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Crystal structure of elongation factor P from Thermus thermophilus HB8 Proc.Natl.Acad.Sci.USA, 101, 2004
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1UC9
| Crystal structure of a lysine biosynthesis enzyme, Lysx, from thermus thermophilus HB8 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, lysine biosynthesis enzyme | 著者 | Sakai, H, Vassylyeva, M.N, Matsuura, T, Sekine, S, Nishiyama, M, Terada, T, Shirouzu, M, Kuramitsu, S, Vassylyev, D.G, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2003-04-09 | 公開日 | 2003-09-23 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | 主引用文献 | Crystal Structure of a Lysine Biosynthesis Enzyme, LysX, from Thermus thermophilus HB8 J.Mol.Biol., 332, 2003
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1UC8
| Crystal structure of a lysine biosynthesis enzyme, Lysx, from thermus thermophilus HB8 | 分子名称: | lysine biosynthesis enzyme | 著者 | Sakai, H, Vassylyeva, M.N, Matsuura, T, Sekine, S, Nishiyama, M, Terada, T, Shirouzu, M, Kuramitsu, S, Vassylyev, D.G, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2003-04-09 | 公開日 | 2003-09-23 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structure of a Lysine Biosynthesis Enzyme, LysX, from Thermus thermophilus HB8 J.Mol.Biol., 332, 2003
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5XON
| RNA Polymerase II elongation complex bound with Spt4/5 and TFIIS | 分子名称: | DNA (48-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ... | 著者 | Ehara, H, Yokoyama, T, Shigematsu, H, Shirouzu, M, Sekine, S. | 登録日 | 2017-05-29 | 公開日 | 2017-08-16 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.83 Å) | 主引用文献 | Structure of the complete elongation complex of RNA polymerase II with basal factors Science, 357, 2017
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3AOI
| RNA polymerase-Gfh1 complex (Crystal type 2) | 分子名称: | Anti-cleavage anti-GreA transcription factor Gfh1, DNA (5'-D(*GP*GP*TP*CP*TP*GP*TP*AP*TP*CP*AP*CP*GP*AP*GP*CP*CP*A*CP*CP*GP*CP*CP*GP*CP*AP*T)-3'), DNA-directed RNA polymerase subunit alpha, ... | 著者 | Tagami, S, Sekine, S, Kumarevel, T, Yamamoto, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2010-09-30 | 公開日 | 2010-12-08 | 最終更新日 | 2024-10-30 | 実験手法 | X-RAY DIFFRACTION (4.3 Å) | 主引用文献 | Crystal structure of bacterial RNA polymerase bound with a transcription inhibitor protein Nature, 468, 2010
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3AOH
| RNA polymerase-Gfh1 complex (Crystal type 1) | 分子名称: | Anti-cleavage anti-GreA transcription factor Gfh1, DNA (5'-D(*GP*GP*TP*CP*TP*GP*TP*AP*TP*CP*AP*CP*GP*AP*GP*CP*CP*AP*CP*CP*GP*CP*CP*GP*CP*AP*T)-3'), DNA-directed RNA polymerase subunit alpha, ... | 著者 | Tagami, S, Sekine, S, Kumarevel, T, Yamamoto, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2010-09-28 | 公開日 | 2010-12-08 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (4.1 Å) | 主引用文献 | Crystal structure of bacterial RNA polymerase bound with a transcription inhibitor protein Nature, 468, 2010
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4WQS
| Thermus thermophilus RNA polymerase backtracked complex | 分子名称: | DNA (28-MER), DNA (5'-D(P*GP*TP*AP*GP*CP*TP*TP*GP*TP*GP*GP*TP*AP*GP*TP*GP*AP*CP*GP*AP*G)-3'), DNA-directed RNA polymerase subunit alpha, ... | 著者 | Murayama, Y, Sekine, S, Yokoyama, S. | 登録日 | 2014-10-22 | 公開日 | 2015-02-18 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (4.306 Å) | 主引用文献 | The Ratcheted and Ratchetable Structural States of RNA Polymerase Underlie Multiple Transcriptional Functions. Mol.Cell, 57, 2015
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4WQT
| Thermus thermophilus RNA polymerase complexed with an RNA cleavage stimulating factor (a GreA/Gfh1 chimeric protein) | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Murayama, Y, Sekine, S, Yokoyama, S. | 登録日 | 2014-10-22 | 公開日 | 2015-02-18 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (4.4 Å) | 主引用文献 | The Ratcheted and Ratchetable Structural States of RNA Polymerase Underlie Multiple Transcriptional Functions. Mol.Cell, 57, 2015
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3AYH
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2DQ0
| Crystal structure of seryl-tRNA synthetase from Pyrococcus horikoshii complexed with a seryl-adenylate analog | 分子名称: | 5'-O-(N-(L-SERYL)-SULFAMOYL)ADENOSINE, SULFATE ION, Seryl-tRNA synthetase | 著者 | Itoh, Y, Sekine, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2006-05-18 | 公開日 | 2007-06-05 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystallographic and mutational studies of seryl-tRNA synthetase from the archaeon Pyrococcus horikoshii. Rna Biol., 5, 2008
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4WRI
| Crystal structure of okadaic acid binding protein 2.1 | 分子名称: | OKADAIC ACID, Okadaic acid binding protein 2-alpha | 著者 | Ehara, H, Makino, M, Kodama, K, Ito, T, Sekine, S, Fukuzawa, S, Yokoyama, S, Tachibana, K. | 登録日 | 2014-10-24 | 公開日 | 2015-05-27 | 最終更新日 | 2020-02-05 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Crystal Structure of Okadaic Acid Binding Protein 2.1: A Sponge Protein Implicated in Cytotoxin Accumulation Chembiochem, 16, 2015
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