1N75
 
 | | Crystal structure of Thermus thermophilus glutamyl-tRNA synthetase complexed with ATP. | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Glutamyl-tRNA synthetase, MAGNESIUM ION | | Authors: | Sekine, S, Nureki, O, Dubois, D.Y, Bernier, S, Chenevert, R, Lapointe, J, Vassylyev, D.G, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2002-11-12 | | Release date: | 2003-02-25 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | ATP binding by glutamyl-tRNA synthetase is switched to the productive mode by tRNA binding
EMBO J., 22, 2003
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1N78
 | | Crystal structure of Thermus thermophilus glutamyl-tRNA synthetase complexed with tRNA(Glu) and glutamol-AMP. | | Descriptor: | GLUTAMOL-AMP, Glutamyl-tRNA synthetase, MAGNESIUM ION, ... | | Authors: | Sekine, S, Nureki, O, Dubois, D.Y, Bernier, S, Chenevert, R, Lapointe, J, Vassylyev, D.G, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2002-11-13 | | Release date: | 2003-02-25 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | ATP binding by glutamyl-tRNA synthetase is switched to the productive mode by tRNA binding
EMBO J., 22, 2003
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1N77
 | | Crystal structure of Thermus thermophilus glutamyl-tRNA synthetase complexed with tRNA(Glu) and ATP. | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Glutamyl-tRNA synthetase, MAGNESIUM ION, ... | | Authors: | Sekine, S, Nureki, O, Dubois, D.Y, Bernier, S, Chenevert, R, Lapointe, J, Vassylyev, D.G, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2002-11-13 | | Release date: | 2003-02-25 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | ATP binding by glutamyl-tRNA synthetase is switched to the productive mode by tRNA binding
EMBO J., 22, 2003
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1G59
 | | GLUTAMYL-TRNA SYNTHETASE COMPLEXED WITH TRNA(GLU). | | Descriptor: | GLUTAMYL-TRNA SYNTHETASE, TRNA(GLU) | | Authors: | Sekine, S, Nureki, O, Shimada, A, Vassylyev, D.G, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2000-10-31 | | Release date: | 2001-09-01 | | Last modified: | 2023-08-02 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural basis for anticodon recognition by discriminating glutamyl-tRNA synthetase.
Nat.Struct.Biol., 8, 2001
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1J09
 | | Crystal structure of Thermus thermophilus glutamyl-tRNA synthetase complexed with ATP and Glu | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, GLUTAMIC ACID, Glutamyl-tRNA synthetase, ... | | Authors: | Sekine, S, Nureki, O, Dubois, D.Y, Bernier, S, Chenevert, R, Lapointe, J, Vassylyev, D.G, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2002-11-12 | | Release date: | 2003-02-25 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | ATP binding by glutamyl-tRNA synthetase is switched to the productive mode by tRNA binding
EMBO J., 22, 2003
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2ZOD
 | | Crystal structure of selenophosphate synthetase from Aquifex aeolicus | | Descriptor: | SULFATE ION, Selenide, water dikinase | | Authors: | Sekine, S.I, Matsumoto, E, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2008-05-09 | | Release date: | 2008-05-27 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.98 Å) | | Cite: | Structure of selenophosphate synthetase essential for selenium incorporation into proteins and RNAs.
J.Mol.Biol., 385, 2009
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2EPG
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2CV1
 | | Glutamyl-tRNA synthetase from Thermus thermophilus in complex with tRNA(Glu), ATP, and an analog of L-glutamate: a quaternary complex | | Descriptor: | (4S)-4-AMINO-5-HYDROXYPENTANOIC ACID, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Sekine, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2005-05-31 | | Release date: | 2006-09-05 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.41 Å) | | Cite: | Glutamyl-tRNA synthetase from Thermus thermophilus in complex with tRNA(Glu), ATP, and an analog of L-glutamate: a quaternary complex
To be Published
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2CV0
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2CUZ
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2DXI
 | | 2.2 A crystal structure of glutamyl-tRNA synthetase from Thermus thermophilus complexed with tRNA(Glu), ATP, and L-glutamol | | Descriptor: | (4S)-4-AMINO-5-HYDROXYPENTANOIC ACID, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Sekine, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2006-08-28 | | Release date: | 2006-10-31 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural bases of transfer RNA-dependent amino acid recognition and activation by glutamyl-tRNA synthetase
Structure, 14, 2006
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2CV2
 | | Glutamyl-tRNA synthetase from Thermus thermophilus in complex with tRNA(Glu) and an enzyme inhibitor, Glu-AMS | | Descriptor: | CHLORIDE ION, MAGNESIUM ION, O5'-(L-GLUTAMYL-SULFAMOYL)-ADENOSINE, ... | | Authors: | Sekine, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2005-05-31 | | Release date: | 2006-09-05 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.69 Å) | | Cite: | Structural bases of transfer RNA-dependent amino acid recognition and activation by glutamyl-tRNA synthetase
Structure, 14, 2006
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2ZAU
 | | Crystal structure of an N-terminally truncated selenophosphate synthetase from Aquifex aeolicus | | Descriptor: | PHOSPHATE ION, Selenide, water dikinase | | Authors: | Sekine, S, Matsumoto, E, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2007-10-10 | | Release date: | 2008-06-17 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structure of an N-terminally truncated selenophosphate synthetase from Aquifex aeolicus
Acta Crystallogr.,Sect.F, 64, 2008
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7YQ8
 | | Cryo-EM structure of human topoisomerase II beta in complex with DNA and etoposide | | Descriptor: | (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol -5-yl 4,6-O-[(1R)-ethylidene]-beta-D-glucopyranoside, 50-mer DNA, DNA topoisomerase 2-beta, ... | | Authors: | Naganuma, M, Ehara, H, Kim, D, Nakagawa, R, Cong, A, Bu, H, Jeong, J, Jang, J, Schellenberg, M.J, Bunch, H, Sekine, S. | | Deposit date: | 2022-08-05 | | Release date: | 2024-01-03 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | ERK2-topoisomerase II regulatory axis is important for gene activation in immediate early genes.
Nat Commun, 14, 2023
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8YFQ
 | | Cryo EM structure of Komagataella phaffii RNAPII-Rat1-Rai1 pre-termination complex | | Descriptor: | 5'-3' exoribonuclease, DNA (90-mer), DNA-directed RNA polymerase subunit, ... | | Authors: | Murayama, Y, Yanagisawa, T, Ehara, H, Sekine, S. | | Deposit date: | 2024-02-25 | | Release date: | 2024-09-25 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Structural basis of eukaryotic transcription termination by the Rat1 exonuclease complex.
Nat Commun, 15, 2024
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8YFR
 | | Cryo EM structure of Komagataella phaffii Rat1-Rai1 complex bound within the RNAPII cleft | | Descriptor: | 5'-3' exoribonuclease, DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ... | | Authors: | Murayama, Y, Yanagisawa, T, Ehara, H, Sekine, S. | | Deposit date: | 2024-02-25 | | Release date: | 2024-09-25 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structural basis of eukaryotic transcription termination by the Rat1 exonuclease complex.
Nat Commun, 15, 2024
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7XSE
 | | RNA polymerase II elongation complex transcribing a nucleosome (EC42) | | Descriptor: | Component of the Paf1p complex, Constituent of Paf1 complex with RNA polymerase II, Paf1p, ... | | Authors: | Ehara, H, Kujirai, T, Shirouzu, M, Kurumizaka, H, Sekine, S. | | Deposit date: | 2022-05-13 | | Release date: | 2022-09-07 | | Last modified: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT.
Science, 377, 2022
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7XSX
 | | RNA polymerase II elongation complex transcribing a nucleosome (EC49) | | Descriptor: | Component of the Paf1p complex, Constituent of Paf1 complex with RNA polymerase II, Paf1p, ... | | Authors: | Ehara, H, Kujirai, T, Shirouzu, M, Kurumizaka, H, Sekine, S. | | Deposit date: | 2022-05-15 | | Release date: | 2022-09-07 | | Last modified: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT.
Science, 377, 2022
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7XTD
 | | RNA polymerase II elongation complex transcribing a nucleosome (EC58oct) | | Descriptor: | Component of the Paf1p complex, Constituent of Paf1 complex with RNA polymerase II, Paf1p, ... | | Authors: | Ehara, H, Kujirai, T, Shirouzu, M, Kurumizaka, H, Sekine, S. | | Deposit date: | 2022-05-16 | | Release date: | 2022-09-07 | | Last modified: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT.
Science, 377, 2022
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7XSZ
 | | RNA polymerase II elongation complex transcribing a nucleosome (EC115) | | Descriptor: | Component of the Paf1p complex, Constituent of Paf1 complex with RNA polymerase II, Paf1p, ... | | Authors: | Ehara, H, Kujirai, T, Shirouzu, M, Kurumizaka, H, Sekine, S. | | Deposit date: | 2022-05-15 | | Release date: | 2022-09-07 | | Last modified: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT.
Science, 377, 2022
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7XTI
 | | RNA polymerase II elongation complex transcribing a nucleosome (EC58hex) | | Descriptor: | Component of the Paf1p complex, Constituent of Paf1 complex with RNA polymerase II, Paf1p, ... | | Authors: | Ehara, H, Kujirai, T, Shirouzu, M, Kurumizaka, H, Sekine, S. | | Deposit date: | 2022-05-17 | | Release date: | 2022-10-12 | | Last modified: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT.
Science, 377, 2022
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7XT7
 | | RNA polymerase II elongation complex transcribing a nucleosome (EC49B) | | Descriptor: | Component of the Paf1p complex, Constituent of Paf1 complex with RNA polymerase II, Paf1p, ... | | Authors: | Ehara, H, Kujirai, T, Shirouzu, M, Kurumizaka, H, Sekine, S. | | Deposit date: | 2022-05-16 | | Release date: | 2022-10-12 | | Last modified: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (4.2 Å) | | Cite: | Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT.
Science, 377, 2022
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8YFE
 | | Cryo EM structure of Komagataella phaffii Rat1-Rai1 complex | | Descriptor: | 5'-3' exoribonuclease, Decapping nuclease | | Authors: | Yanagisawa, T, Murayama, Y, Ehara, H, Sekine, S.I. | | Deposit date: | 2024-02-24 | | Release date: | 2024-09-25 | | Method: | ELECTRON MICROSCOPY (3.47 Å) | | Cite: | Structural basis of eukaryotic transcription termination by the Rat1 exonuclease complex.
Nat Commun, 15, 2024
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8YF5
 | | Cryo EM structure of Komagataella phaffii Rat1-Rai1-Rtt103 complex | | Descriptor: | 5'-3' exoribonuclease, Decapping nuclease, Exonuclease Rat1p and Rai1p interacting protein | | Authors: | Yanagisawa, T, Murayama, Y, Ehara, H, Sekine, S.I. | | Deposit date: | 2024-02-24 | | Release date: | 2024-09-25 | | Method: | ELECTRON MICROSCOPY (3.78 Å) | | Cite: | Structural basis of eukaryotic transcription termination by the Rat1 exonuclease complex.
Nat Commun, 15, 2024
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4WQS
 | | Thermus thermophilus RNA polymerase backtracked complex | | Descriptor: | DNA (28-MER), DNA (5'-D(P*GP*TP*AP*GP*CP*TP*TP*GP*TP*GP*GP*TP*AP*GP*TP*GP*AP*CP*GP*AP*G)-3'), DNA-directed RNA polymerase subunit alpha, ... | | Authors: | Murayama, Y, Sekine, S, Yokoyama, S. | | Deposit date: | 2014-10-22 | | Release date: | 2015-02-18 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (4.306 Å) | | Cite: | The Ratcheted and Ratchetable Structural States of RNA Polymerase Underlie Multiple Transcriptional Functions.
Mol.Cell, 57, 2015
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