4TT0
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4TT1
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2XWH
| HCV-J6 NS5B polymerase structure at 1.8 Angstrom | Descriptor: | DI(HYDROXYETHYL)ETHER, POLYETHYLENE GLYCOL (N=34), RNA DEPENDENT RNA POLYMERASE | Authors: | Scrima, N, Bressanelli, S. | Deposit date: | 2010-11-03 | Release date: | 2011-01-12 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | A Comprehensive Structure-Function Comparison of Hepatitis C Virus Strains Jfh1 and J6 Polymerases Reveals a Key Residue Stimulating Replication in Cell Culture Across Genotypes. J.Virol., 85, 2011
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4ADP
| HCV-J6 NS5B POLYMERASE V405I MUTANT | Descriptor: | RNA-DIRECTED RNA POLYMERASE | Authors: | Scrima, N, Bressanelli, S. | Deposit date: | 2012-01-02 | Release date: | 2012-05-02 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.902 Å) | Cite: | Two Crucial Early Steps in RNA Synthesis by the Hepatitis C Virus Polymerase Involve a Dual Role of Residue 405. J.Virol., 86, 2012
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3Q87
| Structure of E. cuniculi Mtq2-Trm112 complex responible for the methylation of eRF1 translation termination factor | Descriptor: | N6 adenine specific DNA methylase, Putative uncharacterized protein ECU08_1170, S-ADENOSYLMETHIONINE, ... | Authors: | Liger, D, Mora, L, Lazar, N, Figaro, S, Henri, J, Scrima, N, Buckingham, R.H, van Tilbeurgh, H, Heurgue-Hamard, V, Graille, M. | Deposit date: | 2011-01-06 | Release date: | 2011-05-18 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.997 Å) | Cite: | Mechanism of activation of methyltransferases involved in translation by the Trm112 'hub' protein Nucleic Acids Res., 2011
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2B3T
| Structure of complex between E. coli translation termination factor RF1 and the PrmC methyltransferase | Descriptor: | Peptide chain release factor 1, Protein methyltransferase hemK, S-ADENOSYL-L-HOMOCYSTEINE | Authors: | Graille, M, Heurgue-Hamard, V, Champ, S, Mora, L, Scrima, N, Ulryck, N, van Tilbeurgh, H, Buckingham, R.H. | Deposit date: | 2005-09-21 | Release date: | 2006-01-24 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Molecular basis for bacterial class I release factor methylation by PrmC Mol.Cell, 20, 2005
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2J6A
| Structure of S. cerevisiae Trm112 protein, a methyltransferase activator | Descriptor: | 1,2-ETHANEDIOL, PROTEIN TRM112, ZINC ION | Authors: | Heurgue-Hamard, V, Graille, M, Scrima, N, Ulryck, N, Champ, S, Van Tilbeurgh, H, Buckingham, R.H. | Deposit date: | 2006-09-27 | Release date: | 2006-09-28 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The Zinc Finger Protein Ynr046W is Plurifunctional and a Component of the Erf1 Methyltransferase in Yeast. J.Biol.Chem., 281, 2006
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