8F5B
| Human ABCA4 structure in complex with AMP-PNP | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | Authors: | Scortecci, J.F, Van Petegem, F, Molday, R.S. | Deposit date: | 2022-11-13 | Release date: | 2023-11-22 | Last modified: | 2024-09-18 | Method: | ELECTRON MICROSCOPY (3.95 Å) | Cite: | Structural and functional characterization of the nucleotide-binding domains of ABCA4 and their role in Stargardt disease. J.Biol.Chem., 300, 2024
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6NDN
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7M1P
| Human ABCA4 structure in the unbound state | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Retinal-specific phospholipid-transporting ATPase ABCA4, ... | Authors: | Scortecci, J.F, Van Petegem, F, Molday, R.S. | Deposit date: | 2021-03-14 | Release date: | 2021-09-08 | Last modified: | 2024-10-23 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Cryo-EM structures of the ABCA4 importer reveal mechanisms underlying substrate binding and Stargardt disease. Nat Commun, 12, 2021
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7M1Q
| Human ABCA4 structure in complex with N-ret-PE | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, MAGNESIUM ION, Retinal-specific phospholipid-transporting ATPase ABCA4, ... | Authors: | Scortecci, J.F, Van Petegem, F, Molday, R.S. | Deposit date: | 2021-03-14 | Release date: | 2021-09-08 | Last modified: | 2021-10-20 | Method: | ELECTRON MICROSCOPY (2.92 Å) | Cite: | Cryo-EM structures of the ABCA4 importer reveal mechanisms underlying substrate binding and Stargardt disease. Nat Commun, 12, 2021
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