5DCA
| Crystal structure of yeast full length Brr2 in complex with Prp8 Jab1 domain | Descriptor: | Pre-mRNA-splicing factor 8, Pre-mRNA-splicing helicase BRR2 | Authors: | Absmeier, E, Wollenhaupt, J, Santos, K.F, Wahl, M.C. | Deposit date: | 2015-08-23 | Release date: | 2015-12-16 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | The large N-terminal region of the Brr2 RNA helicase guides productive spliceosome activation. Genes Dev., 29, 2015
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6QV3
| Crystal structure of the Ski2 RNA-helicase Brr2 from Chaetomium thermophilum bound to ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, DI(HYDROXYETHYL)ETHER, MANGANESE (II) ION, ... | Authors: | Absmeier, E, Santos, K.F, Wahl, M.C. | Deposit date: | 2019-03-01 | Release date: | 2020-01-15 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Molecular Mechanism Underlying Inhibition of Intrinsic ATPase Activity in a Ski2-like RNA Helicase. Structure, 28, 2020
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6QWS
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6QV4
| Crystal structure of the Ski2 RNA-helicase Brr2 from Chaetomium thermophilum bound to ATP-gamma-S | Descriptor: | ACETATE ION, MANGANESE (II) ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | Authors: | Absmeier, E, Santos, K.F, Wahl, M.C. | Deposit date: | 2019-03-01 | Release date: | 2020-01-15 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Molecular Mechanism Underlying Inhibition of Intrinsic ATPase Activity in a Ski2-like RNA Helicase. Structure, 28, 2020
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4KIT
| Crystal structure of human Brr2 in complex with the Prp8 Jab1/MPN domain | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Pre-mRNA-processing-splicing factor 8, ... | Authors: | Wahl, M.C, Wandersleben, T, Santos, K.F. | Deposit date: | 2013-05-02 | Release date: | 2013-06-05 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.598 Å) | Cite: | Inhibition of RNA helicase Brr2 by the C-terminal tail of the spliceosomal protein Prp8. Science, 341, 2013
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3SBS
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3SBT
| Crystal structure of a Aar2-Prp8 complex | Descriptor: | A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8, S-1,2-PROPANEDIOL, ... | Authors: | Weber, G, Santos, K.F, Holton, N, Wahl, M.C. | Deposit date: | 2011-06-06 | Release date: | 2011-07-27 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.799 Å) | Cite: | Mechanism for Aar2p function as a U5 snRNP assembly factor. Genes Dev., 25, 2011
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7WRK
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