3W9H
 
 | | Structural basis for the inhibition of bacterial multidrug exporters | | 分子名称: | Acriflavine resistance protein B, [{2-[({[(3R)-1-{8-[(4-tert-butyl-1,3-thiazol-2-yl)carbamoyl]-4-oxo-3-[(E)-2-(1H-tetrazol-5-yl)ethenyl]-4H-pyrido[1,2-a]pyrimidin-2-yl}piperidin-3-yl]oxy}carbonyl)amino]ethyl}(dimethyl)ammonio]acetate | | 著者 | Sakurai, K, Nagata, C, Nakashima, R, Yamaguchi, A. | | 登録日 | 2013-04-04 | | 公開日 | 2013-07-03 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | | 主引用文献 | Structural basis for the inhibition of bacterial multidrug exporters
Nature, 500, 2013
|
|
2ZUH
 | | Crystal Structure of Camphor-soaked Ferric Cytochrome P450cam Mutant (D297A) | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CAMPHOR, Camphor 5-monooxygenase, ... | | 著者 | Sakurai, K, Harada, K, Shimada, H, Shimokata, K, Hayashi, T, Tsukihara, T. | | 登録日 | 2008-10-18 | | 公開日 | 2009-10-20 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Crystal Structure of Camphor-soaked Ferric Cytochrome P450cam Mutant
to be published
|
|
2ZUI
 | | Crystal Structure of Camphor-soaked Ferric Cytochrome P450cam Mutant (D297N) | | 分子名称: | CAMPHOR, Camphor 5-monooxygenase, POTASSIUM ION, ... | | 著者 | Sakurai, K, Harada, K, Shimada, H, Shimokata, K, Hayashi, T, Tsukihara, T. | | 登録日 | 2008-10-18 | | 公開日 | 2009-10-20 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Crystal Structure of Camphor-soaked Ferric Cytochrome P450cam Mutant
TO BE PUBLISHED
|
|
2ZUJ
 | | Crystal Structure of Camphor-soaked Ferric Cytochrome P450cam Mutant(D297L) | | 分子名称: | CAMPHOR, Camphor 5-monooxygenase, POTASSIUM ION, ... | | 著者 | Sakurai, K, Harada, K, Shimada, H, Shimokata, K, Hayashi, T, Tsukihara, T. | | 登録日 | 2008-10-18 | | 公開日 | 2009-10-20 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Crystal Structure of Camphor-soaked Ferric Cytochrome P450cam Mutant
to be published
|
|
3W9I
 | | Structural basis for the inhibition of bacterial multidrug exporters | | 分子名称: | DODECYL-BETA-D-MALTOSIDE, Multidrug resistance protein MexB | | 著者 | Sakurai, K, Nakashima, R, Hayashi, K, Yamaguchi, A. | | 登録日 | 2013-04-04 | | 公開日 | 2013-07-03 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | | 主引用文献 | Structural basis for the inhibition of bacterial multidrug exporters
Nature, 500, 2013
|
|
3W9J
 | | Structural basis for the inhibition of bacterial multidrug exporters | | 分子名称: | DODECYL-BETA-D-MALTOSIDE, Multidrug resistance protein MexB, [{2-[({[(3R)-1-{8-[(4-tert-butyl-1,3-thiazol-2-yl)carbamoyl]-4-oxo-3-[(E)-2-(1H-tetrazol-5-yl)ethenyl]-4H-pyrido[1,2-a]pyrimidin-2-yl}piperidin-3-yl]oxy}carbonyl)amino]ethyl}(dimethyl)ammonio]acetate | | 著者 | Sakurai, K, Nakashima, R, Hayashi, K, Yamaguchi, A. | | 登録日 | 2013-04-04 | | 公開日 | 2013-07-03 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | | 主引用文献 | Structural basis for the inhibition of bacterial multidrug exporters
Nature, 500, 2013
|
|
2ZAX
 | | Crystal Structure of Ferric Cytochrome P450cam | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CAMPHOR, Cytochrome P450-cam, ... | | 著者 | Sakurai, K, Shimada, H, Harada, K, Hayashi, T, Tsukihara, T. | | 登録日 | 2007-10-11 | | 公開日 | 2008-01-01 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Evaluation of the functional role of the heme-6-propionate side chain in cytochrome P450cam
J.Am.Chem.Soc., 130, 2008
|
|
3VVZ
 | | Crystal Strucuture of The Rhodamine 6G-Bound Form of RamR (Transcriptional Regurator of TetR Family) from Salmonella Typhimurium | | 分子名称: | Putative regulatory protein, RHODAMINE 6G, SULFATE ION | | 著者 | Sakurai, K, Nikaido, E, Nakashima, R, Yamasaki, S, Yamaguchi, A, Nishino, K. | | 登録日 | 2012-07-30 | | 公開日 | 2013-07-03 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | | 主引用文献 | The crystal structure of multidrug-resistance regulator RamR with multiple drugs
Nat Commun, 4, 2013
|
|
3VVY
 | | Crystal Strucuture of The Ethidium-Bound Form of RamR (Transcriptional Regurator of TetR Family) from Salmonella Typhimurium | | 分子名称: | ETHIDIUM, Putative regulatory protein | | 著者 | Sakurai, K, Nikaido, E, Nakashima, R, Yamasaki, S, Yamaguchi, A, Nishino, K. | | 登録日 | 2012-07-30 | | 公開日 | 2013-07-03 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | | 主引用文献 | The crystal structure of multidrug-resistance regulator RamR with multiple drugs
Nat Commun, 4, 2013
|
|
3VVX
 | | Crystal Strucuture of RamR (Transcriptional Regurator of TetR Family) from Salmonella Typhimurium | | 分子名称: | Putative regulatory protein, SULFATE ION | | 著者 | Sakurai, K, Nikaido, E, Nakashima, R, Yamasaki, S, Yamaguchi, A, Nishino, K. | | 登録日 | 2012-07-30 | | 公開日 | 2013-07-03 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | The crystal structure of multidrug-resistance regulator RamR with multiple drugs
Nat Commun, 4, 2013
|
|
3VW1
 | | Crystal Strucuture of the Crystal Violet-Bound Form of RamR (Transcriptional Regurator of TetR Family) from Salmonella Typhimurium | | 分子名称: | CHLORIDE ION, CRYSTAL VIOLET, Putative regulatory protein, ... | | 著者 | Sakurai, K, Yamasaki, S, Nakashima, R, Nikaido, E, Yamaguchi, A, Nishino, K. | | 登録日 | 2012-07-30 | | 公開日 | 2013-07-03 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | | 主引用文献 | The crystal structure of multidrug-resistance regulator RamR with multiple drugs
Nat Commun, 4, 2013
|
|
3VW0
 | | Crystal Structure of The Dequalinum-bound Form of RamR (Transcriptional Regulator of TetR Family) From Salmonella Typhimurium | | 分子名称: | DEQUALINIUM, Putative regulatory protein, SULFATE ION | | 著者 | Sakurai, K, Yamasaki, S, Nakashima, R, Nikaido, E, Yamaguchi, A, Nishino, K. | | 登録日 | 2012-07-30 | | 公開日 | 2013-07-03 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | The crystal structure of multidrug-resistance regulator RamR with multiple drugs
Nat Commun, 4, 2013
|
|
3VW2
 | | Crystal Strucuture of The Berberine-bound Form of RamR (Transcriptional Regurator of TetR Family) from Salmonella Typhimurium | | 分子名称: | BERBERINE, Putative regulatory protein, SULFATE ION | | 著者 | Sakurai, K, Nikaido, E, Nakashima, R, Yamasaki, S, Yamaguchi, A, Nishino, K. | | 登録日 | 2012-07-30 | | 公開日 | 2013-07-03 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | | 主引用文献 | The crystal structure of multidrug-resistance regulator RamR with multiple drugs
Nat Commun, 4, 2013
|
|
2ZWU
 | | Crystal Structure of Camphor Soaked Ferric Cytochrome P450cam | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CAMPHOR, Camphor 5-monooxygenase, ... | | 著者 | Sakurai, K, Shimada, H, Hayashi, T, Tsukihara, T. | | 登録日 | 2008-12-18 | | 公開日 | 2009-02-17 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Substrate binding induces structural changes in cytochrome P450cam
Acta Crystallogr.,Sect.F, 65, 2009
|
|
2ZWT
 | | Crystal Structure of Ferric Cytochrome P450cam | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CAMPHOR, Camphor 5-monooxygenase, ... | | 著者 | Sakurai, K, Shimada, H, Hayashi, T, Tsukihara, T. | | 登録日 | 2008-12-18 | | 公開日 | 2009-02-17 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | Substrate binding induces structural changes in cytochrome P450cam
Acta Crystallogr.,Sect.F, 65, 2009
|
|
5YIL
 | | Hoisting-loop in bacterial multidrug exporter AcrB is a highly flexible hinge that enables the large motion of the subdomains | | 分子名称: | Multidrug efflux pump subunit AcrB | | 著者 | Zwama, M, Sakurai, K, Hayashi, K, Nakashima, R, Kitagawa, K, Nishino, K, Yamaguchi, A. | | 登録日 | 2017-10-05 | | 公開日 | 2017-11-15 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Hoisting-Loop in Bacterial Multidrug Exporter AcrB Is a Highly Flexible Hinge That Enables the Large Motion of the Subdomains.
Front Microbiol, 8, 2017
|
|
6IIA
 | | MexB in complex with LMNG | | 分子名称: | Lauryl Maltose Neopentyl Glycol, Multidrug resistance protein MexB | | 著者 | Nakashima, R, Sakurai, K, Nakao, K. | | 登録日 | 2018-10-04 | | 公開日 | 2019-03-27 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.91 Å) | | 主引用文献 | Crystal structures of multidrug efflux pump MexB bound with high-molecular-mass compounds.
Sci Rep, 9, 2019
|
|
3WRL
 | | Crystal structure of P450cam | | 分子名称: | CAMPHOR, Camphor 5-monooxygenase, POTASSIUM ION, ... | | 著者 | Kishimoto, A, Takagi, K, Amano, A, Sakurai, K, Mizushima, T, Shimada, H. | | 登録日 | 2014-02-25 | | 公開日 | 2015-03-18 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Structure of P450cam intermedite
To be published
|
|
3WRK
 | | Crystal structure of P450cam | | 分子名称: | CAMPHOR, Camphor 5-monooxygenase, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Kishimoto, A, Takagi, K, Amano, A, Sakurai, K, Mizushima, T, Shimada, H. | | 登録日 | 2014-02-25 | | 公開日 | 2015-03-18 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.609 Å) | | 主引用文献 | Structure of P450cam intermedite
To be Published
|
|
3WRH
 | | Crystal structure of P450cam | | 分子名称: | CAMPHOR, Camphor 5-monooxygenase, POTASSIUM ION, ... | | 著者 | Kishimoto, A, Takagi, K, Amano, A, Sakurai, K, Mizushima, T, Shimada, H. | | 登録日 | 2014-02-25 | | 公開日 | 2015-03-18 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | | 主引用文献 | Structure of P450cam intermedite
To be Published
|
|
6IE9
 | | RamR in complex with chenodeoxycholic acid | | 分子名称: | CHENODEOXYCHOLIC ACID, Regulatory protein, SULFATE ION | | 著者 | Nakashima, R, Sakurai, K, Yamasaki, S, Nishino, K. | | 登録日 | 2018-09-13 | | 公開日 | 2019-02-13 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | Crystal structure of the multidrug resistance regulator RamR complexed with bile acids.
Sci Rep, 9, 2019
|
|
6IE8
 | | RamR in complex with cholic acid | | 分子名称: | CHOLIC ACID, Regulatory protein, SULFATE ION | | 著者 | Nakashima, R, Sakurai, K, Yamasaki, S, Nishino, K. | | 登録日 | 2018-09-13 | | 公開日 | 2019-02-13 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of the multidrug resistance regulator RamR complexed with bile acids.
Sci Rep, 9, 2019
|
|
3AOD
 | | Structures of the multidrug exporter AcrB reveal a proximal multisite drug-binding pocket | | 分子名称: | (4S,4AS,5AR,12AS)-4,7-BIS(DIMETHYLAMINO)-3,10,12,12A-TETRAHYDROXY-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2- CARBOXAMIDE, Acriflavine resistance protein B, RIFAMPICIN | | 著者 | Nakashima, R, Sakurai, K, Yamaguchi, A. | | 登録日 | 2010-09-23 | | 公開日 | 2011-11-30 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Structures of the multidrug exporter AcrB reveal a proximal multisite drug-binding pocket
Nature, 480, 2011
|
|
3AOC
 | |
3AOA
 | |
