2TCT
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2BNZ
| Structural basis for cooperative binding of Ribbon-Helix-Helix Omega repressor to inverted DNA heptad repeats | Descriptor: | 5'-D(*CP*TP*AP*AP*TP*CP*AP*CP*TP*TP *GP*TP*GP*AP*TP*TP*CP*G)-3', 5'-D(*GP*AP*AP*TP*CP*AP*CP*AP*AP*GP *TP*GP*AP*TP*TP*AP*GP*C)-3', ORF OMEGA | Authors: | Weihofen, W.A, Cicek, A, Pratto, F, Alonso, J.C, Saenger, W. | Deposit date: | 2005-04-06 | Release date: | 2006-03-15 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structures of Omega Repressors Bound to Direct and Inverted DNA Repeats Explain Modulation of Transcription. Nucleic Acids Res., 34, 2006
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2BNW
| Structural basis for cooperative binding of Ribbon-Helix-Helix Omega repressor to direct DNA heptad repeats | Descriptor: | 5'-D(*CP*TP*TP*GP*TP*GP*AP*TP*TP*TP *GP*TP*GP*AP*TP*TP*CP*G)-3', 5'-D(*GP*AP*AP*TP*CP*AP*CP*AP*AP*AP *TP*CP*AP*CP*AP*AP*GP*C)-3', ORF OMEGA | Authors: | Weihofen, W.A, Cicek, A, Pratto, F, Alonso, J.C, Saenger, W. | Deposit date: | 2005-04-05 | Release date: | 2006-03-15 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Structures of Omega Repressors Bound to Direct and Inverted DNA Repeats Explain Modulation of Transcription. Nucleic Acids Res., 34, 2006
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1W72
| Crystal structure of HLA-A1:MAGE-A1 in complex with Fab-Hyb3 | Descriptor: | BETA-2-MICROGLOBULIN, GLYCEROL, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ... | Authors: | Hulsmeyer, M, Chames, P, Hillig, R.C, Stanfield, R.L, Held, G, Coulie, P.G, Alings, C, Wille, G, Saenger, W, Uchanska-Ziegler, B, Hoogenboom, H.R, Ziegler, A. | Deposit date: | 2004-08-27 | Release date: | 2004-11-09 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | A Major Histocompatibility Complex.Peptide- Restricted Antibody and T Cell Receptor Molecules Recognize Their Target by Distinct Binding Modes: Crystal Structure of Human Leukocyte Antigen (Hla)-A1.Mage-A1 in Complex with Fab-Hyb3 J.Biol.Chem., 280, 2005
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2CAX
| STRUCTURAL BASIS FOR COOPERATIVE BINDING OF RIBBON-HELIX-HELIX REPRESSOR OMEGA TO MUTATED DIRECT DNA HEPTAD REPEATS | Descriptor: | 5'-D(*CP*TP*TP*GP*TP*GP*AP*CP*TP*TP *GP*TP*GP*AP*TP*TP*CP*G)-3', 5'-D(*GP*AP*AP*TP*CP*AP*CP*AP*AP*AP *TP*CP*AP*CP*AP*AP*G)-3', 5'-D(*GP*AP*AP*TP*CP*AP*CP*AP*AP*GP *TP*CP*AP*CP*AP*AP*GP*C)-3', ... | Authors: | Weihofen, W.A, Cicek, A, Pratto, F, Alonso, J.C, Saenger, W. | Deposit date: | 2005-12-23 | Release date: | 2006-03-15 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structures of Omega Repressors Bound to Direct and Inverted DNA Repeats Explain Modulation of Transcription. Nucleic Acids Res., 34, 2006
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2CTX
| THE REFINED CRYSTAL STRUCTURE OF ALPHA-COBRATOXIN FROM NAJA NAJA SIAMENSIS AT 2.4-ANGSTROMS RESOLUTION | Descriptor: | ALPHA-COBRATOXIN | Authors: | Betzel, C, Lange, G, Pal, G.P, Wilson, K.S, Maelicke, A, Saenger, W. | Deposit date: | 1991-09-24 | Release date: | 1993-10-31 | Last modified: | 2017-11-29 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | The refined crystal structure of alpha-cobratoxin from Naja naja siamensis at 2.4-A resolution. J.Biol.Chem., 266, 1991
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1NLF
| Crystal Structure of DNA Helicase RepA in complex with sulfate at 1.95 A resolution | Descriptor: | Regulatory protein repA, SULFATE ION | Authors: | Xu, H, Strater, N, Schroeder, W, Bottcher, C, Ludwig, K, Saenger, W. | Deposit date: | 2003-01-07 | Release date: | 2003-04-29 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structure of DNA helicase RepA in complex with sulfate at 1.95 A resolution implicates structural changes to an "open" form. Acta Crystallogr.,Sect.D, 59, 2003
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2AXT
| Crystal Structure of Photosystem II from Thermosynechococcus elongatus | Descriptor: | (1S)-2-(ALPHA-L-ALLOPYRANOSYLOXY)-1-[(TRIDECANOYLOXY)METHYL]ETHYL PALMITATE, 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, ... | Authors: | Loll, B, Kern, J, Saenger, W, Zouni, A, Biesiadka, J. | Deposit date: | 2005-09-06 | Release date: | 2005-12-27 | Last modified: | 2017-12-20 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Towards complete cofactor arrangement in the 3.0 A resolution structure of photosystem II NATURE, 438, 2005
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1FXU
| PURINE NUCLEOSIDE PHOSPHORYLASE FROM CALF SPLEEN IN COMPLEX WITH N(7)-ACYCLOGUANOSINE INHIBITOR AND A PHOSPHATE ION | Descriptor: | 2-AMINO-7-[2-(2-HYDROXY-1-HYDROXYMETHYL-ETHYLAMINO)-ETHYL]-1,7-DIHYDRO-PURIN-6-ONE, MAGNESIUM ION, PHOSPHATE ION, ... | Authors: | Luic, M, Bzowska, A, Shugar, D, Saenger, W, Koellner, G. | Deposit date: | 2000-09-27 | Release date: | 2000-10-18 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Calf spleen purine nucleoside phosphorylase: structure of its ternary complex with an N(7)-acycloguanosine inhibitor and a phosphate anion. Acta Crystallogr.,Sect.D, 57, 2001
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1JGE
| HLA-B*2705 bound to nona-peptide m9 | Descriptor: | BETA-2-MICROGLOBULIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, B-27 B*2705 ALPHA CHAIN, ... | Authors: | Hulsmeyer, M, Hillig, R.C, Volz, A, Ruhl, M, Schroder, W, Saenger, W, Ziegler, A, Uchanska-Ziegler, B. | Deposit date: | 2001-06-25 | Release date: | 2002-10-30 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | HLA-B27 subtypes differentially associated with disease exhibit subtle structural
alterations J.Biol.Chem., 277, 2002
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1K5N
| HLA-B*2709 BOUND TO NONA-PEPTIDE M9 | Descriptor: | GLYCEROL, beta-2-microglobulin, light chain, ... | Authors: | Hulsmeyer, M, Hillig, R.C, Volz, A, Ruhl, M, Schroder, W, Saenger, W, Ziegler, A, Uchanska-Ziegler, B. | Deposit date: | 2001-10-11 | Release date: | 2002-10-30 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.09 Å) | Cite: | HLA-B27 Subtypes Differentially Associated with Disease Exhibit Subtle Structural Alterations J.Biol.Chem., 277, 2002
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1C3X
| PURINE NUCLEOSIDE PHOSPHORYLASE FROM CELLULOMONAS SP. IN COMPLEX WITH 8-IODO-GUANINE | Descriptor: | 8-IODO-GUANINE, CALCIUM ION, PENTOSYLTRANSFERASE, ... | Authors: | Tebbe, J, Bzowska, A, Wielgus-Kutrowska, B, Schroeder, W, Kazimierczuk, Z, Shugar, D, Saenger, W, Koellner, G. | Deposit date: | 1999-07-29 | Release date: | 1999-12-22 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of the purine nucleoside phosphorylase (PNP) from Cellulomonas sp. and its implication for the mechanism of trimeric PNPs. J.Mol.Biol., 294, 1999
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1K9S
| PURINE NUCLEOSIDE PHOSPHORYLASE FROM E. COLI IN COMPLEX WITH FORMYCIN A DERIVATIVE AND PHOSPHATE | Descriptor: | 2-(7-AMINO-6-METHYL-3H-PYRAZOLO[4,3-D]PYRIMIDIN-3-YL)-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3,4-DIOL, 2-HYDROXYMETHYL-5-(7-METHYLAMINO-3H-PYRAZOLO[4,3-D]PYRIMIDIN-3-YL)-TETRAHYDRO-FURAN-3,4-DIOL, PHOSPHATE ION, ... | Authors: | Koellner, G, Bzowska, A, Wielgus-Kutrowska, B, Luic, M, Steiner, T, Saenger, W, Stepinski, J. | Deposit date: | 2001-10-30 | Release date: | 2001-11-28 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Open and closed conformation of the E. coli purine nucleoside phosphorylase active center and implications for the catalytic mechanism. J.Mol.Biol., 315, 2002
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2BJ6
| Crystal Structure of a decameric HNA-RNA hybrid | Descriptor: | 5'-R(*GP*GP*CP*AP*UP*UP*AP*CP*GP*GP)-3', SULFATE ION, SYNTHETIC HNA | Authors: | Maier, T, Przylas, I, Straeter, N, Herdewijn, P, Saenger, W. | Deposit date: | 2005-01-30 | Release date: | 2005-03-09 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Reinforced Hna Backbone Hydration in the Crystal Structure of a Decameric Hna/RNA Hybrid J.Am.Chem.Soc., 127, 2005
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1TRQ
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4V2F
| Tetracycline repressor TetR(D), unliganded | Descriptor: | TETRACYCLINE REPRESSOR PROTEIN CLASS D | Authors: | Werten, S, Orth, P, Saenger, W, Hinrichs, W. | Deposit date: | 2014-10-09 | Release date: | 2014-12-10 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Tetracycline Repressor Allostery Does not Depend on Divalent Metal Recognition. Biochemistry, 53, 2014
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1PTK
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1G8Y
| CRYSTAL STRUCTURE OF THE HEXAMERIC REPLICATIVE HELICASE REPA OF PLASMID RSF1010 | Descriptor: | REGULATORY PROTEIN REPA | Authors: | Niedenzu, T, Roeleke, D, Bains, G, Scherzinger, E, Saenger, W. | Deposit date: | 2000-11-21 | Release date: | 2001-02-14 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of the hexameric replicative helicase RepA of plasmid RSF1010. J.Mol.Biol., 306, 2001
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1QPI
| CRYSTAL STRUCTURE OF TETRACYCLINE REPRESSOR/OPERATOR COMPLEX | Descriptor: | DNA (5'-D(*CP*CP*TP*AP*TP*CP*AP*AP*TP*GP*AP*TP*AP*GP*A)-3'), DNA (5'-D(*TP*CP*TP*AP*TP*CP*AP*TP*TP*GP*AP*TP*AP*GP*G)-3'), IMIDAZOLE, ... | Authors: | Orth, P, Schnappinger, D, Hillen, W, Saenger, W, Hinrichs, W. | Deposit date: | 1999-05-25 | Release date: | 2000-02-28 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural basis of gene regulation by the tetracycline inducible Tet repressor-operator system. Nat.Struct.Biol., 7, 2000
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1TRP
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3BO8
| The High Resolution Crystal Structure of HLA-A1 Complexed with the MAGE-A1 Peptide | Descriptor: | Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ... | Authors: | Kumar, P, Vahedi-Faridi, A, Saenger, W, Ziegler, A, Uchanska-Ziegler, B. | Deposit date: | 2007-12-17 | Release date: | 2008-12-23 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Conformational changes within the HLA-A1:MAGE-A1 complex induced by binding of a recombinant antibody fragment with TCR-like specificity Protein Sci., 18, 2009
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3BVN
| High resolution crystal structure of HLA-B*1402 in complex with the latent membrane protein 2 peptide (LMP2) of Epstein-Barr virus | Descriptor: | Beta-2-microglobulin, HLA class I histocompatibility antigen, B*1402 alpha chain, ... | Authors: | Kumar, P, Vahedi-Faridi, A, Saenger, W, Uchanska-Ziegler, B, Ziegler, A. | Deposit date: | 2008-01-07 | Release date: | 2009-02-03 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Structural basis for T cell alloreactivity among three HLA-B14 and HLA-B27 antigens J.Biol.Chem., 284, 2009
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1FE1
| CRYSTAL STRUCTURE PHOTOSYSTEM II | Descriptor: | 2-[(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL)-AMINO]-2-METHYL-SUCCINIC ACID, CADMIUM ION, CHLOROPHYLL A, ... | Authors: | Zouni, A, Witt, H.-T, Kern, J, Fromme, P, Krauss, N, Saenger, W, Orth, P. | Deposit date: | 2000-07-20 | Release date: | 2001-02-14 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | Crystal structure of photosystem II from Synechococcus elongatus at 3.8 A resolution. Nature, 409, 2001
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3DTX
| Crystal structure of HLA-B*2705 complexed with the double citrullinated vasoactive intestinal peptide type 1 receptor (VIPR) peptide (residues 400-408) | Descriptor: | Beta-2-microglobulin, Double citrullinated vasoactive intestinal polypeptide receptor, MHC class I antigen (Fragment) | Authors: | Beltrami, A, Gabdulkhakov, A, Rossmann, M, Ziegler, A, Uchanska-Ziegler, B, Saenger, W. | Deposit date: | 2008-07-16 | Release date: | 2009-05-05 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Citrullination-and mhc polymorphism-dependent conformational changes of a self peptide To be Published
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3H25
| Crystal structure of the catalytic domain of primase Repb' in complex with initiator DNA | Descriptor: | Replication protein B, SINGLE STRANDED INITIATOR DNA (SSIA) | Authors: | Geibel, S, Banchenko, S, Engel, M, Lanka, E, Saenger, W. | Deposit date: | 2009-04-14 | Release date: | 2009-04-28 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structure and function of primase RepB' encoded by broad-host-range plasmid RSF1010 that replicates exclusively in leading-strand mode Proc.Natl.Acad.Sci.USA, 106, 2009
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