5E27
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![BU of 5e27 by Molmil](/molmil-images/mine/5e27) | The structure of Resuscitation Promoting Factor B from M. tuberculosis reveals unexpected ubiquitin-like domains | Descriptor: | Resuscitation-promoting factor RpfB | Authors: | Ruggiero, A, Squeglia, F, Romano, M, Vitagliano, L, De Simone, A, Berisio, R. | Deposit date: | 2015-09-30 | Release date: | 2015-11-18 | Last modified: | 2015-12-23 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | The structure of Resuscitation promoting factor B from M. tuberculosis reveals unexpected ubiquitin-like domains. Biochim.Biophys.Acta, 1860, 2015
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6Y16
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![BU of 6y16 by Molmil](/molmil-images/mine/6y16) | CRYSTAL STRUCTURE OF TMARGBP DOMAIN 1 IN COMPLEX WITH THE GUANIDINIUM ION | Descriptor: | 1,2-ETHANEDIOL, Amino acid ABC transporter, periplasmic amino acid-binding protein,Amino acid ABC transporter, ... | Authors: | Ruggiero, A, Balasco, N, Smaldone, G, Graziano, G, Vitagliano, L. | Deposit date: | 2020-02-11 | Release date: | 2020-07-15 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Guanidinium binding to proteins: The intriguing effects on the D1 and D2 domains of Thermotoga maritima Arginine Binding Protein and a comprehensive analysis of the Protein Data Bank. Int.J.Biol.Macromol., 163, 2020
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3H5K
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![BU of 3h5k by Molmil](/molmil-images/mine/3h5k) | Crystal structure of the ribosome inactivating protein PDL1 | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Ribosome-inactivating protein PD-L1/PD-L2 | Authors: | Ruggiero, A, Di Maro, A, Severino, V, Chambery, A, Berisio, R. | Deposit date: | 2009-04-22 | Release date: | 2009-10-13 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Crystal structure of PD-L1, a ribosome inactivating protein from Phytolacca dioica L. Leaves with the property to induce DNA cleavage Biopolymers, 91, 2009
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3LE7
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![BU of 3le7 by Molmil](/molmil-images/mine/3le7) | Crystal structure of PD-L1 from P. dioica in complex with adenine | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENINE, Ribosome-inactivating protein PD-L1/PD-L2 | Authors: | Ruggiero, A, Berisio, R. | Deposit date: | 2010-01-14 | Release date: | 2010-04-14 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | The role of the glycan moiety on the structure-function relationships of PD-L1, type 1 ribosome-inactivating protein from P. dioica leaves Mol Biosyst, 6, 2010
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3HHV
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![BU of 3hhv by Molmil](/molmil-images/mine/3hhv) | The crystal structure of the Thioredoxin A2 from Sulfolobus solfataricus | Descriptor: | Thioredoxin (TrxA-2) | Authors: | Ruggiero, A, Masullo, M, Ruocco, M.R, Arcari, P, Zagari, A, Vitagliano, L. | Deposit date: | 2009-05-18 | Release date: | 2009-10-27 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | The dimeric structure of Sulfolobus solfataricus thioredoxin A2 and the basis of its thermostability Proteins, 77, 2009
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3PY9
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![BU of 3py9 by Molmil](/molmil-images/mine/3py9) | X-ray structural studies of the entire extra-cellular region of the Ser/Thr kinase PrkC from Staphylococcus aureus | Descriptor: | EUROPIUM ION, Protein kinase | Authors: | Ruggiero, A, Squeglia, F, Marasco, D, Marchetti, R, Molinaro, A, Berisio, R. | Deposit date: | 2010-12-12 | Release date: | 2011-01-19 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | X-ray structural studies of the entire extracellular region of the serine/threonine kinase PrkC from Staphylococcus aureus. Biochem.J., 435, 2011
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4EMN
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![BU of 4emn by Molmil](/molmil-images/mine/4emn) | Crystal structure of RpfB catalytic domain in complex with benzamidine | Descriptor: | BENZAMIDINE, Probable resuscitation-promoting factor rpfB, SULFATE ION | Authors: | Ruggiero, A, Marchant, J, Squeglia, F, Makarov, V, De Simone, A, Berisio, R. | Deposit date: | 2012-04-12 | Release date: | 2013-02-27 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.17 Å) | Cite: | Molecular determinants of inactivation of the resuscitation promoting factor B from Mycobacterium tuberculosis. J.Biomol.Struct.Dyn., 31, 2013
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2Z4U
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![BU of 2z4u by Molmil](/molmil-images/mine/2z4u) | |
3NE0
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![BU of 3ne0 by Molmil](/molmil-images/mine/3ne0) | |
4JMN
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![BU of 4jmn by Molmil](/molmil-images/mine/4jmn) | Crystal structure of LD transpeptidase LdtMt1 from M. tuberculosis | Descriptor: | Probable L,D-transpeptidase LdtA | Authors: | Ruggiero, A, Correale, S, Berisio, R. | Deposit date: | 2013-03-14 | Release date: | 2013-10-23 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structures of free and inhibited forms of the L,D-transpeptidase LdtMt1 from Mycobacterium tuberculosis. Acta Crystallogr.,Sect.D, 69, 2013
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3F8P
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![BU of 3f8p by Molmil](/molmil-images/mine/3f8p) | Structure of Sulfolobus solfataricus TrxR-B3 | Descriptor: | ACETIC ACID, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION, ... | Authors: | Ruggiero, A, Masullo, M, Ruocco, M.R, Arcari, P, Zagari, A, Vitagliano, L. | Deposit date: | 2008-11-13 | Release date: | 2009-01-13 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure and stability of a thioredoxin reductase from Sulfolobus solfataricus: a thermostable protein with two functions Biochim.Biophys.Acta, 1794, 2009
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3F8D
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![BU of 3f8d by Molmil](/molmil-images/mine/3f8d) | Structure of Sulfolobus solfataricus Thioredoxin reductase Mutant C147A | Descriptor: | ACETIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION, ... | Authors: | Ruggiero, A, Masullo, M, Ruocco, M.R, Arcari, P, Zagari, A, Vitagliano, L. | Deposit date: | 2008-11-12 | Release date: | 2009-01-13 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structure and stability of a thioredoxin reductase from Sulfolobus solfataricus: a thermostable protein with two functions Biochim.Biophys.Acta, 1794, 2009
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3F8R
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![BU of 3f8r by Molmil](/molmil-images/mine/3f8r) | Crystal structure of Sulfolobus solfataricus Thioredoxin reductase B3 in complex with two NADP molecules | Descriptor: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Thioredoxin reductase (TrxB-3) | Authors: | Ruggiero, A, Masullo, M, Ruocco, M.R, Arcari, P, Zagari, A, Vitagliano, L. | Deposit date: | 2008-11-13 | Release date: | 2009-01-13 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structure and stability of a thioredoxin reductase from Sulfolobus solfataricus: a thermostable protein with two functions Biochim.Biophys.Acta, 1794, 2009
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2QET
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![BU of 2qet by Molmil](/molmil-images/mine/2qet) | |
2QES
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![BU of 2qes by Molmil](/molmil-images/mine/2qes) | |
4PSH
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![BU of 4psh by Molmil](/molmil-images/mine/4psh) | Structure of holo ArgBP from T. maritima | Descriptor: | ABC-type transporter, periplasmic subunit family 3, ARGININE | Authors: | Ruggiero, A, Dattelbaum, J.D, Staiano, M, Berisio, R, D'Auria, S, Vitagliano, L. | Deposit date: | 2014-03-07 | Release date: | 2014-07-23 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | A loose domain swapping organization confers a remarkable stability to the dimeric structure of the arginine binding protein from Thermotoga maritima Plos One, 9, 2014
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4PRS
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![BU of 4prs by Molmil](/molmil-images/mine/4prs) | Structure of apo ArgBP from T. maritima | Descriptor: | ABC-type transporter, periplasmic subunit family 3 | Authors: | Ruggiero, A, Dattelbaum, J.D, Staiano, M, Berisio, R, D'Auria, S, Vitagliano, L. | Deposit date: | 2014-03-06 | Release date: | 2014-07-23 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.47 Å) | Cite: | A loose domain swapping organization confers a remarkable stability to the dimeric structure of the arginine binding protein from Thermotoga maritima Plos One, 9, 2014
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3EO5
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![BU of 3eo5 by Molmil](/molmil-images/mine/3eo5) | Crystal structure of the resuscitation promoting factor RpfB | Descriptor: | Resuscitation-promoting factor rpfB | Authors: | Ruggiero, A, Tizzano, B, Pedone, E, Pedone, C, Wilmanns, M, Berisio, R. | Deposit date: | 2008-09-26 | Release date: | 2009-01-13 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | Crystal Structure of the Resuscitation-Promoting Factor (DeltaDUF)RpfB from M. tuberculosis J.Mol.Biol., 385, 2009
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6H1Y
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![BU of 6h1y by Molmil](/molmil-images/mine/6h1y) | CRYSTAL STRUCTURE OF A CHIMERIC VARIANT OF THIOREDOXIN FROM ESCHERICHIA COLI | Descriptor: | Thioredoxin 1,Thioredoxin (TrxA-1),Thioredoxin 1 | Authors: | Ruggiero, A, Smaldone, G, Esposito, L, Balasco, N, Vitagliano, L. | Deposit date: | 2018-07-12 | Release date: | 2019-02-06 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.99 Å) | Cite: | Loop size optimization induces a strong thermal stabilization of the thioredoxin fold. Febs J., 286, 2019
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5EOC
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![BU of 5eoc by Molmil](/molmil-images/mine/5eoc) | Crystal structure of Fab C2 in complex with a Cyclic variant of Hepatitis C Virus E2 epitope I | Descriptor: | ALA-CYS-GLN-LEU-ILE-ASN-THR-ASN-GLY-SER-TRP-HIS-ILE-CYS, Fab fragment (Heavy chain), Fab fragment (Light chain) | Authors: | Berisio, R, Ruggiero, A, Sandomenico, A, Patel, A.H, Ruvo, M, Vitagliano, L. | Deposit date: | 2015-11-10 | Release date: | 2016-02-10 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Generation and Characterization of Monoclonal Antibodies against a Cyclic Variant of Hepatitis C Virus E2 Epitope 412-422. J.Virol., 90, 2016
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1SKQ
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![BU of 1skq by Molmil](/molmil-images/mine/1skq) | The crystal structure of Sulfolobus solfataricus elongation factor 1-alpha in complex with magnesium and GDP | Descriptor: | Elongation factor 1-alpha, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION | Authors: | Vitagliano, L, Ruggiero, A, Masullo, M, Cantiello, P, Arcari, P, Zagari, A. | Deposit date: | 2004-03-05 | Release date: | 2004-07-20 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The crystal structure of Sulfolobus solfataricus elongation factor 1alpha in complex with magnesium and GDP. Biochemistry, 43, 2004
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7A99
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![BU of 7a99 by Molmil](/molmil-images/mine/7a99) | Crystal structure of the Phe57Trp mutant of the arginine-bound form of domain 1 from TmArgBP | Descriptor: | ACETATE ION, ARGININE, Amino acid ABC transporter, ... | Authors: | Balasco, N, Vitagliano, L, Smaldone, G, Ruggiero, A. | Deposit date: | 2020-09-01 | Release date: | 2020-11-04 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Development of a Protein Scaffold for Arginine Sensing Generated through the Dissection of the Arginine-Binding Protein from Thermotoga maritima . Int J Mol Sci, 21, 2020
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5LKW
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![BU of 5lkw by Molmil](/molmil-images/mine/5lkw) | |
6SVF
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![BU of 6svf by Molmil](/molmil-images/mine/6svf) | Crystal structure of the P235GK mutant of ArgBP from T. maritima | Descriptor: | ARGININE, Amino acid ABC transporter, periplasmic amino acid-binding protein | Authors: | Vitagliano, L, Berisio, R, Esposito, L, Balasco, N, Smaldone, G, Ruggiero, A. | Deposit date: | 2019-09-18 | Release date: | 2019-11-20 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | The non-swapped monomeric structure of the arginine-binding protein from Thermotoga maritima. Acta Crystallogr.,Sect.F, 75, 2019
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3TCO
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![BU of 3tco by Molmil](/molmil-images/mine/3tco) | Crystallographic and spectroscopic characterization of Sulfolobus solfataricus TrxA1 provide insights into the determinants of thioredoxin fold stability | Descriptor: | 1,2-ETHANEDIOL, Thioredoxin (TrxA-1) | Authors: | Esposito, L, Ruggiero, A, Masullo, M, Ruocco, M.R, Lamberti, A, Arcari, P, Zagari, A, Vitagliano, L. | Deposit date: | 2011-08-09 | Release date: | 2011-11-30 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystallographic and spectroscopic characterizations of Sulfolobus solfataricus TrxA1 provide insights into the determinants of thioredoxin fold stability. J.Struct.Biol., 177, 2012
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