7OJJ
| Lassa virus L protein with endonuclease and C-terminal domains in close proximity [MID-LINK] | 分子名称: | MAGNESIUM ION, RNA-directed RNA polymerase L, ZINC ION | 著者 | Kouba, T, Vogel, D, Thorkelsson, S, Quemin, E, Williams, H.M, Milewski, M, Busch, C, Gunther, S, Grunewald, K, Rosenthal, M, Cusack, S. | 登録日 | 2021-05-16 | 公開日 | 2021-12-01 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Conformational changes in Lassa virus L protein associated with promoter binding and RNA synthesis activity. Nat Commun, 12, 2021
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7OJL
| Lassa virus L protein in a pre-initiation conformation [PREINITIATION] | 分子名称: | 3' RNA, 5' RNA, MANGANESE (II) ION, ... | 著者 | Kouba, T, Vogel, D, Thorkelsson, S, Quemin, E, Williams, H.M, Milewski, M, Busch, C, Gunther, S, Grunewald, K, Rosenthal, M, Cusack, S. | 登録日 | 2021-05-16 | 公開日 | 2021-12-01 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Conformational changes in Lassa virus L protein associated with promoter binding and RNA synthesis activity. Nat Commun, 12, 2021
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4KVJ
| Crystal structure of Oryza sativa fatty acid alpha-dioxygenase with hydrogen peroxide | 分子名称: | 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, CALCIUM ION, CHLORIDE ION, ... | 著者 | Zhu, G, Koszelak-Rosenblum, M, Malkowski, M.G. | 登録日 | 2013-05-22 | 公開日 | 2013-08-21 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | 主引用文献 | Crystal structures of alpha-dioxygenase from Oryza sativa: Insights into substrate binding and activation by hydrogen peroxide. Protein Sci., 22, 2013
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4KVL
| Crystal structure of Oryza sativa fatty acid alpha-dioxygenase Y379F with palmitic acid | 分子名称: | CALCIUM ION, CHLORIDE ION, Fatty acid alpha-oxidase, ... | 著者 | Zhu, G, Koszelak-Rosenblum, M, Malkowski, M.G. | 登録日 | 2013-05-22 | 公開日 | 2013-08-21 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | Crystal structures of alpha-dioxygenase from Oryza sativa: Insights into substrate binding and activation by hydrogen peroxide. Protein Sci., 22, 2013
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4KVK
| Crystal structure of Oryza sativa fatty acid alpha-dioxygenase | 分子名称: | CALCIUM ION, CHLORIDE ION, DECYL-BETA-D-MALTOPYRANOSIDE, ... | 著者 | Zhu, G, Koszelak-Rosenblum, M, Malkowski, M.G. | 登録日 | 2013-05-22 | 公開日 | 2013-08-21 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Crystal structures of alpha-dioxygenase from Oryza sativa: Insights into substrate binding and activation by hydrogen peroxide. Protein Sci., 22, 2013
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6WNL
| human Artemis/SNM1C catalytic domain, crystal form 2 | 分子名称: | Protein artemis, ZINC ION | 著者 | Karim, F, Liu, S, Laciak, A.R, Volk, L, Rosenblum, M, Curtis, R, Huang, N, Carr, G, Zhu, G. | 登録日 | 2020-04-22 | 公開日 | 2020-07-01 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.37 Å) | 主引用文献 | Structural analysis of the catalytic domain of Artemis endonuclease/SNM1C reveals distinct structural features. J.Biol.Chem., 295, 2020
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3K8G
| Structure of crystal form I of TP0453 | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 30kLP | 著者 | Zhu, G, Luthra, A, Desrosiers, D, Koszelak-Rosenblum, M, Mulay, V, Radolf, J.D, Malkowski, M.G. | 登録日 | 2009-10-14 | 公開日 | 2010-10-27 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | The Transition from Closed to Open Conformation of Treponema pallidum Outer Membrane-associated Lipoprotein TP0453 Involves Membrane Sensing and Integration by Two Amphipathic Helices. J.Biol.Chem., 286, 2011
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3K8I
| Structure of crystal form IV of TP0453 | 分子名称: | 30kLP | 著者 | Zhu, G, Luthra, A, Desrosiers, D, Koszelak-Rosenblum, M, Mulay, V, Radolf, J.D, Malkowski, M.G. | 登録日 | 2009-10-14 | 公開日 | 2010-10-27 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The Transition from Closed to Open Conformation of Treponema pallidum Outer Membrane-associated Lipoprotein TP0453 Involves Membrane Sensing and Integration by Two Amphipathic Helices. J.Biol.Chem., 286, 2011
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8ASG
| Structure of the SFTSV L protein bound in a resting state [RESTING] | 分子名称: | MAGNESIUM ION, RNA (5'-R(*AP*CP*AP*CP*AP*GP*AP*GP*AP*CP*GP*CP*CP*CP*AP*GP*AP*UP*GP*A*)-3'), RNA (5'-R(*GP*AP*UP*CP*UP*GP*GP*GP*CP*GP*GP*UP*CP*UP*UP*UP*GP*UP*GP*U*)-3'), ... | 著者 | Williams, H.M, Thorkelsson, S.R, Vogel, D, Milewski, M, Busch, C, Cusack, S, Grunewald, K, Quemin, E.R.J, Rosenthal, M. | 登録日 | 2022-08-19 | 公開日 | 2023-01-18 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural insights into viral genome replication by the severe fever with thrombocytopenia syndrome virus L protein. Nucleic Acids Res., 51, 2023
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8ASB
| Structure of the SFTSV L protein stalled at early elongation with the endonuclease domain in a raised conformation [EARLY-ELONGATION-ENDO] | 分子名称: | 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine, MAGNESIUM ION, RNA (5'-R(*AP*CP*AP*CP*AP*GP*AP*GP*AP*CP*GP*CP*CP*CP*AP*GP*A)-3'), ... | 著者 | Williams, H.M, Thorkelsson, S.R, Vogel, D, Milewski, M, Busch, C, Cusack, S, Grunewald, K, Quemin, E.R.J, Rosenthal, M. | 登録日 | 2022-08-18 | 公開日 | 2023-01-18 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structural insights into viral genome replication by the severe fever with thrombocytopenia syndrome virus L protein. Nucleic Acids Res., 51, 2023
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1BL1
| PTH RECEPTOR N-TERMINUS FRAGMENT, NMR, 1 STRUCTURE | 分子名称: | PARATHYROID HORMONE RECEPTOR | 著者 | Pellegrini, M, Bisello, A, Rosenblatt, M, Chorev, M, Mierke, D.F. | 登録日 | 1998-07-22 | 公開日 | 1999-03-30 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Binding domain of human parathyroid hormone receptor: from conformation to function. Biochemistry, 37, 1998
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8ASD
| Structure of the SFTSV L protein stalled at late elongation [LATE-ELONGATION] | 分子名称: | 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine, MAGNESIUM ION, RNA (5'-R(P*AP*AP*AP*AP*AP*AP*GP*AP*UP*CP*UP*GP*GP*GP*CP*GP*GP*UP*CP*UP*UP*UP*GP*UP*GP*U)-3'), ... | 著者 | Williams, H.M, Thorkelsson, S.R, Vogel, D, Milewski, M, Busch, C, Cusack, S, Grunewald, K, Quemin, E.R.J, Rosenthal, M. | 登録日 | 2022-08-19 | 公開日 | 2023-01-18 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Structural insights into viral genome replication by the severe fever with thrombocytopenia syndrome virus L protein. Nucleic Acids Res., 51, 2023
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8AS7
| Structure of the SFTSV L protein stalled at early elongation [EARLY-ELONGATION] | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine, MAGNESIUM ION, ... | 著者 | Williams, H.M, Thorkelsson, S.R, Vogel, D, Milewski, M, Busch, C, Cusack, S, Grunewald, K, Quemin, E.R.J, Rosenthal, M. | 登録日 | 2022-08-18 | 公開日 | 2023-01-18 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Structural insights into viral genome replication by the severe fever with thrombocytopenia syndrome virus L protein. Nucleic Acids Res., 51, 2023
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8AS6
| Structure of the SFTSV L protein bound to 5' cRNA hook [5' HOOK] | 分子名称: | RNA (5'-R(*AP*CP*AP*CP*AP*GP*AP*GP*AP*CP*GP*CP*CP*C)-3'), RNA-dependent RNA-polymerase L protein | 著者 | Williams, H.M, Thorkelsson, S.R, Vogel, D, Milewski, M, Busch, C, Cusack, S, Grunewald, K, Quemin, E.R.J, Rosenthal, M. | 登録日 | 2022-08-18 | 公開日 | 2023-01-18 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structural insights into viral genome replication by the severe fever with thrombocytopenia syndrome virus L protein. Nucleic Acids Res., 51, 2023
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1TXT
| Staphylococcus aureus 3-hydroxy-3-methylglutaryl-CoA synthase | 分子名称: | 3-hydroxy-3-methylglutaryl-CoA synthase, ACETOACETYL-COENZYME A | 著者 | Campobasso, N, Patel, M, Wilding, I.E, Kallender, H, Rosenberg, M, Gwynn, M. | 登録日 | 2004-07-06 | 公開日 | 2004-08-31 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.501 Å) | 主引用文献 | Staphylococcus aureus 3-hydroxy-3-methylglutaryl-CoA synthase: crystal structure and mechanism J.Biol.Chem., 279, 2004
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1TVZ
| Crystal structure of 3-hydroxy-3-methylglutaryl-coenzyme A synthase from Staphylococcus aureus | 分子名称: | 3-hydroxy-3-methylglutaryl-CoA synthase, SULFATE ION | 著者 | Campobasso, N, Patel, M, Wilding, I.E, Kallender, H, Rosenberg, M, Gwynn, M. | 登録日 | 2004-06-30 | 公開日 | 2004-08-31 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Staphylococcus aureus 3-hydroxy-3-methylglutaryl-CoA synthase: crystal structure and mechanism J.Biol.Chem., 279, 2004
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8CI5
| Structure of the SNV L protein bound to 5' RNA | 分子名称: | RNA (5'-R(P*AP*GP*UP*AP*GP*UP*AP*GP*AP*CP*U)-3'), RNA-directed RNA polymerase L | 著者 | Meier, K, Thorkelsson, S.R, Durieux Trouilleton, Q, Vogel, D, Yu, D, Kosinski, J, Cusack, S, Malet, H, Grunewald, K, Quemin, E.R.J, Rosenthal, M. | 登録日 | 2023-02-08 | 公開日 | 2023-07-19 | 最終更新日 | 2023-08-23 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural and functional characterization of the Sin Nombre virus L protein. Plos Pathog., 19, 2023
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6XYA
| Cap-binding domain of SFTSV L protein | 分子名称: | 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, RNA-dependent RNA polymerase, SODIUM ION | 著者 | Gogrefe, N, Guenther, S, Rosenthal, M. | 登録日 | 2020-01-30 | 公開日 | 2020-04-08 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Structural and functional characterization of the severe fever with thrombocytopenia syndrome virus L protein. Nucleic Acids Res., 48, 2020
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3K8J
| Structure of crystal form III of TP0453 | 分子名称: | 30kLP | 著者 | Zhu, G, Luthra, A, Desrosiers, D, Koszelak-Rosenblum, M, Mulay, V, Radolf, J.D, Malkowski, M.G. | 登録日 | 2009-10-14 | 公開日 | 2010-10-27 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The Transition from Closed to Open Conformation of Treponema pallidum Outer Membrane-associated Lipoprotein TP0453 Involves Membrane Sensing and Integration by Two Amphipathic Helices. J.Biol.Chem., 286, 2011
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3K8H
| Structure of crystal form I of TP0453 | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 30kLP | 著者 | Zhu, G, Luthra, A, Desrosiers, D, Koszelak-Rosenblum, M, Mulay, V, Radolf, J.D, Malkowski, M.G. | 登録日 | 2009-10-14 | 公開日 | 2010-10-27 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | 主引用文献 | The Transition from Closed to Open Conformation of Treponema pallidum Outer Membrane-associated Lipoprotein TP0453 Involves Membrane Sensing and Integration by Two Amphipathic Helices. J.Biol.Chem., 286, 2011
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6QHG
| Structure of the cap-binding domain of Rift Valley Fever virus L protein | 分子名称: | 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, GLYCEROL, PHOSPHATE ION, ... | 著者 | Gogrefe, N, Reindl, S, Gunther, S, Rosenthal, M. | 登録日 | 2019-01-16 | 公開日 | 2019-05-22 | 最終更新日 | 2019-06-05 | 実験手法 | X-RAY DIFFRACTION (1.483 Å) | 主引用文献 | Structure of a functional cap-binding domain in Rift Valley fever virus L protein. Plos Pathog., 15, 2019
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7ALP
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6Y6K
| Cryo-EM structure of a Phenuiviridae L protein | 分子名称: | MAGNESIUM ION, RNA-dependent RNA polymerase | 著者 | Vogel, D, Thorkelsson, S.R, Quemin, E, Meier, K, Kouba, T, Gogrefe, N, Busch, C, Reindl, S, Guenther, S, Cusack, S, Gruenewald, K, Rosenthal, M. | 登録日 | 2020-02-26 | 公開日 | 2020-04-08 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.78 Å) | 主引用文献 | Structural and functional characterization of the severe fever with thrombocytopenia syndrome virus L protein. Nucleic Acids Res., 48, 2020
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2P09
| Structural Insights into the Evolution of a Non-Biological Protein | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, PENTAETHYLENE GLYCOL, ... | 著者 | Smith, M, Rosenow, M, Wang, M, Allen, J.P, Szostak, J.W, Chaput, J.C. | 登録日 | 2007-02-28 | 公開日 | 2007-06-05 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Structural insights into the evolution of a non-biological protein: importance of surface residues in protein fold optimization. PLoS ONE, 2, 2007
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2P05
| Structural Insights into the Evolution of a Non-Biological Protein | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, PENTAETHYLENE GLYCOL, ... | 著者 | Smith, M, Rosenow, M, Wang, M, Allen, J.P, Szostak, J.W, Chaput, J.C. | 登録日 | 2007-02-28 | 公開日 | 2007-06-05 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural insights into the evolution of a non-biological protein: importance of surface residues in protein fold optimization. PLoS ONE, 2, 2007
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