7YXU
 
 | | Crystal structure of agonistic antibody 1618 fab domain bound to human 4-1BB. | | 分子名称: | MANGANESE (II) ION, Tumor necrosis factor receptor superfamily member 9, heavy chain of Fab, ... | | 著者 | Hakansson, M, Rose, N, Petersson, J, Enell Smith, K, Thorolfsson, M, von Schantz, L. | | 登録日 | 2022-02-16 | | 公開日 | 2023-01-25 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | | 主引用文献 | The Bispecific Tumor Antigen-Conditional 4-1BB x 5T4 Agonist, ALG.APV-527, Mediates Strong T-Cell Activation and Potent Antitumor Activity in Preclinical Studies.
Mol.Cancer Ther., 22, 2023
|
|
8OZ3
 | | Crystal structure of scFv ATOR 1017 bound to human 4-1BB | | 分子名称: | Single chain Fv, Tumor necrosis factor receptor superfamily member 9 | | 著者 | Hakansson, M, Von Schantz, L, Rose, N. | | 登録日 | 2023-05-08 | | 公開日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | ATOR-1017 (evunzekibart), an Fc-gamma receptor conditional 4-1BB agonist designed for optimal safety and efficacy, activates exhausted T cells in combination with anti-PD-1.
Cancer Immunol.Immunother., 72, 2023
|
|
7R58
 | | Crystal structure of the GPVI-glenzocimab complex | | 分子名称: | CHLORIDE ION, Fab heavy chain, Fab light chain, ... | | 著者 | Jandrot-Perrus, M, Lebozec, K, Rose, N, Welin, M, Billiald, P. | | 登録日 | 2022-02-10 | | 公開日 | 2022-11-16 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.902 Å) | | 主引用文献 | Targeting platelet GPVI with glenzocimab: a novel mechanism for inhibition.
Blood Adv, 7, 2023
|
|
