9JO4
 
 | | Cryo-EM structure of human BKca channel-compound 51b complex | | Descriptor: | 5-(5-morpholin-4-ylpentylamino)-2-[2,3,5,6-tetrakis(fluoranyl)-4-(trifluoromethyl)phenoxy]phenol, CALCIUM ION, CHOLESTEROL HEMISUCCINATE, ... | | Authors: | Kim, S, Park, S, Lee, N.Y, Lee, E.Y, Lee, N, Roh, E.C, Kim, Y.G, Kim, H.J, Jin, M.S, Park, C.S, Kim, Y.C. | | Deposit date: | 2024-09-24 | | Release date: | 2025-02-26 | | Last modified: | 2025-03-12 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Discovery of Diphenyl Ether Derivatives as Novel BK Ca Channel Activators: Structure-Activity Relationship, Cryo-EM Complex Structures, and In Vivo Animal Studies.
J.Med.Chem., 68, 2025
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9JO3
 | | Cryo-EM structure of human BKca channel-compound 10b complex | | Descriptor: | 5-azanyl-2-[2,3,5,6-tetrakis(fluoranyl)-4-(trifluoromethyl)phenoxy]phenol, CALCIUM ION, CHOLESTEROL HEMISUCCINATE, ... | | Authors: | Kim, S, Park, S, Lee, N.Y, Lee, E.Y, Lee, N, Roh, E.C, Kim, Y.G, Kim, H.J, Jin, M.S, Park, C.S, Kim, Y.C. | | Deposit date: | 2024-09-24 | | Release date: | 2025-02-26 | | Last modified: | 2025-03-12 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Discovery of Diphenyl Ether Derivatives as Novel BK Ca Channel Activators: Structure-Activity Relationship, Cryo-EM Complex Structures, and In Vivo Animal Studies.
J.Med.Chem., 68, 2025
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