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PDB: 334 件

5UOH
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Crystal Structure of Hip1 (Rv2224c) T466A mutant
分子名称: Carboxylesterase A
著者Naffin-Olivos, J.L, Daab, A, White, A, Goldfarb, N, Milne, A.C, Liu, D, Baikovitz, J, Dunn, B.M, Rengarajan, J, Petsko, G.A, Ringe, D.
登録日2017-01-31
公開日2017-04-12
最終更新日2019-12-11
実験手法X-RAY DIFFRACTION (2.609 Å)
主引用文献Structure Determination of Mycobacterium tuberculosis Serine Protease Hip1 (Rv2224c).
Biochemistry, 56, 2017
5UGQ
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Crystal Structure of Hip1 (Rv2224c)
分子名称: Carboxylesterase A
著者Naffin-Olivos, J.L, Daab, A, White, A, Goldfarb, N, Milne, A.C, Liu, D, Dunn, B.M, Rengarajan, J, Petsko, G.A, Ringe, D.
登録日2017-01-09
公開日2017-04-12
最終更新日2019-12-11
実験手法X-RAY DIFFRACTION (2.609 Å)
主引用文献Structure Determination of Mycobacterium tuberculosis Serine Protease Hip1 (Rv2224c).
Biochemistry, 56, 2017
1OT5
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The 2.4 Angstrom Crystal Structure of Kex2 in complex with a peptidyl-boronic acid inhibitor
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ac-Ala-Lys-boroArg N-acetylated boronic acid peptide inhibitor, ...
著者Holyoak, T, Wilson, M.A, Fenn, T.D, Kettner, C.A, Petsko, G.A, Fuller, R.S, Ringe, D.
登録日2003-03-21
公開日2003-06-17
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献2.4 A Resolution Crystal Structure of the Prototypical Hormone-Processing Protease Kex2 in Complex with an Ala-Lys-Arg Boronic Acid Inhibitor
Biochemistry, 42, 2003
3B3W
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Crystal structure of the S228A mutant of the aminopeptidase from Vibrio proteolyticus in complex with leucine
分子名称: Bacterial leucyl aminopeptidase, LEUCINE, SODIUM ION, ...
著者Ataie, N.J, Hoang, Q.Q, Zahniser, M.P.D, Milne, A, Petsko, G.A, Ringe, D.
登録日2007-10-22
公開日2007-11-27
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Zinc coordination geometry and ligand binding affinity: the structural and kinetic analysis of the second-shell serine 228 residue and the methionine 180 residue of the aminopeptidase from Vibrio proteolyticus.
Biochemistry, 47, 2008
2ACU
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TYROSINE-48 IS THE PROTON DONOR AND HISTIDINE-110 DIRECTS SUBSTRATE STEREOCHEMICAL SELECTIVITY IN THE REDUCTION REACTION OF HUMAN ALDOSE REDUCTASE: ENZYME KINETICS AND THE CRYSTAL STRUCTURE OF THE Y48H MUTANT ENZYME
分子名称: ALDOSE REDUCTASE, CITRIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Bohren, K.M, Grimshaw, C.E, Lai, C.-J, Gabbay, K.H, Petsko, G.A, Harrison, D.H, Ringe, D.
登録日1994-04-15
公開日1994-07-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Tyrosine-48 is the proton donor and histidine-110 directs substrate stereochemical selectivity in the reduction reaction of human aldose reductase: enzyme kinetics and crystal structure of the Y48H mutant enzyme.
Biochemistry, 33, 1994
5UNO
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BU of 5uno by Molmil
Crystal Structure of Hip1 (Rv2224c)
分子名称: Carboxylesterase A
著者Naffin-Olivos, J.L, Daab, A, White, A, Goldfarb, N, Milne, A.C, Liu, D, Dunn, B.M, Rengarajan, J, Petsko, G.A, Ringe, D.
登録日2017-01-31
公開日2017-04-12
最終更新日2019-12-11
実験手法X-RAY DIFFRACTION (2.603 Å)
主引用文献Structure Determination of Mycobacterium tuberculosis Serine Protease Hip1 (Rv2224c).
Biochemistry, 56, 2017
2AAT
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2.8-ANGSTROMS-RESOLUTION CRYSTAL STRUCTURE OF AN ACTIVE-SITE MUTANT OF ASPARTATE AMINOTRANSFERASE FROM ESCHERICHIA COLI
分子名称: 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, ASPARTATE AMINOTRANSFERASE, SULFATE ION
著者Smith, D, Almo, S.C, Toney, M, Ringe, D.
登録日1989-05-30
公開日1989-10-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献2.8-A-resolution crystal structure of an active-site mutant of aspartate aminotransferase from Escherichia coli.
Biochemistry, 28, 1989
2QQ9
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Crystal Structure of DtxR(D6A C102D) Complexed with Nickel(II)
分子名称: Diphtheria toxin repressor, NICKEL (II) ION, PHOSPHATE ION
著者D'Aquino, J.A, Lattimer, J.R, Denninger, A, D'Aquino, K.E, Ringe, D.
登録日2007-07-26
公開日2007-10-30
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献Role of the N-Terminal Helix in the Metal Ion-Induced Activation of the Diphtheria Toxin Repressor DtxR.
Biochemistry, 46, 2007
2QQA
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Crystal Structure of DtxR(E9A C102D) Complexed with Nickel(II)
分子名称: Diphtheria toxin repressor, NICKEL (II) ION, PHOSPHATE ION
著者D'Aquino, J.A, Lattimer, J.R, Denninger, A, D'Aquino, K.E, Ringe, D.
登録日2007-07-26
公開日2007-10-30
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Role of the N-Terminal Helix in the Metal Ion-Induced Activation of the Diphtheria Toxin Repressor DtxR.
Biochemistry, 46, 2007
1NIU
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ALANINE RACEMASE WITH BOUND INHIBITOR DERIVED FROM L-CYCLOSERINE
分子名称: Alanine Racemase, D-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-N,O-CYCLOSERYLAMIDE
著者Fenn, T.D, Stamper, G.F, Morollo, A.A, Ringe, D.
登録日2002-12-26
公開日2003-09-16
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献A side reaction of alanine racemase: transamination of cycloserine.
Biochemistry, 42, 2003
3QZ9
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Crystal structure of Co-type nitrile hydratase beta-Y215F from Pseudomonas putida.
分子名称: COBALT (III) ION, Co-type Nitrile Hydratase alpha subunit, Co-type Nitrile Hydratase beta subunit, ...
著者Brodkin, H.R, Novak, W.R.P, Ringe, D, Petsko, G.A.
登録日2011-03-04
公開日2011-03-23
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Evidence of the Participation of Remote Residues in the Catalytic Activity of Co-Type Nitrile Hydratase from Pseudomonas putida.
Biochemistry, 50, 2011
3QYG
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Crystal Structure of Co-type Nitrile Hydratase beta-E56Q from Pseudomonas putida.
分子名称: COBALT (III) ION, Co-type Nitrile Hydratase alpha subunit, Co-type Nitrile Hydratase beta subunit, ...
著者Brodkin, H.R, Novak, W.R.P, Ringe, D, Petsko, G.A.
登録日2011-03-03
公開日2011-03-23
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Evidence of the Participation of Remote Residues in the Catalytic Activity of Co-Type Nitrile Hydratase from Pseudomonas putida.
Biochemistry, 50, 2011
3QZ5
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Crystal Structure of Co-type Nitrile Hydratase alpha-E168Q from Pseudomonas putida.
分子名称: COBALT (III) ION, Co-type Nitrile Hydratase alpha subunit, Co-type Nitrile Hydratase beta subunit, ...
著者Brodkin, H.R, Novak, W.R.P, Ringe, D, Petsko, G.A.
登録日2011-03-04
公開日2011-03-23
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Evidence of the Participation of Remote Residues in the Catalytic Activity of Co-Type Nitrile Hydratase from Pseudomonas putida.
Biochemistry, 50, 2011
3RHN
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HISTIDINE TRIAD NUCLEOTIDE-BINDING PROTEIN (HINT) FROM RABBIT COMPLEXED WITH GMP
分子名称: GUANOSINE-5'-MONOPHOSPHATE, HISTIDINE TRIAD NUCLEOTIDE-BINDING PROTEIN
著者Brenner, C, Garrison, P, Gilmour, J, Peisach, D, Ringe, D, Petsko, G.A, Lowenstein, J.M.
登録日1997-02-11
公開日1997-06-16
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structures of HINT demonstrate that histidine triad proteins are GalT-related nucleotide-binding proteins.
Nat.Struct.Biol., 4, 1997
3F6E
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Crystal structure of benzoylformate decarboxylase in complex with the pyridyl inhibitor 3-PKB
分子名称: 3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}ethyl)-2-[(1S,2E)-1-hydroxy-3-pyridin-3-ylprop-2-en-1-yl]-4-methyl-1,3-thiazol-3-ium, Benzoylformate decarboxylase, MAGNESIUM ION
著者Brandt, G.S, McLeish, M.J, Kenyon, G.L, Petsko, G.A, Ringe, D, Jordan, F.
登録日2008-11-05
公開日2008-12-09
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.34 Å)
主引用文献Detection and time course of formation of major thiamin diphosphate-bound covalent intermediates derived from a chromophoric substrate analogue on benzoylformate decarboxylase.
Biochemistry, 48, 2009
1P92
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Crystal Structure of (H79A)DtxR
分子名称: BETA-MERCAPTOETHANOL, Diphtheria toxin repressor
著者D'Aquino, J.A, Ringe, D.
登録日2003-05-08
公開日2004-05-25
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Determinants of the SRC homology domain 3-like fold.
J.Bacteriol., 185, 2003
3F6B
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Crystal structure of benzoylformate decarboxylase in complex with the pyridyl inhibitor PAA
分子名称: 3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}ethyl)-2-[(1S,2E)-1-hydroxy-3-pyridin-3-ylprop-2-en-1-yl]-4-methyl-1,3-thiazol-3-ium, Benzoylformate decarboxylase, MAGNESIUM ION
著者Brandt, G.S, McLeish, M.J, Kenyon, G.L, Petsko, G.A, Ringe, D, Jordan, F.
登録日2008-11-05
公開日2008-12-09
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.34 Å)
主引用文献Detection and time course of formation of major thiamin diphosphate-bound covalent intermediates derived from a chromophoric substrate analogue on benzoylformate decarboxylase.
Biochemistry, 48, 2009
3TGK
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TRYPSINOGEN MUTANT D194N AND DELETION OF ILE 16-VAL 17 COMPLEXED WITH BOVINE PANCREATIC TRYPSIN INHIBITOR (BPTI)
分子名称: CALCIUM ION, PANCREATIC TRYPSIN INHIBITOR, SULFATE ION, ...
著者Pasternak, A, White, A, Jeffery, C.J, Medina, N, Cahoon, M, Ringe, D, Hedstrom, L.
登録日1998-07-19
公開日2001-07-04
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The energetic cost of induced fit catalysis: Crystal structures of trypsinogen mutants with enhanced activity and inhibitor affinity.
Protein Sci., 10, 2001
2P8O
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Crystal Structure of a Benzohydroxamic Acid/Vanadate complex bound to chymotrypsin A
分子名称: Chymotrypsin A chain A, Chymotrypsin A chain B, Chymotrypsin A chain C, ...
著者Moulin, A, Bell, J.H, Pratt, R.F, Ringe, D.
登録日2007-03-22
公開日2007-05-08
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Inhibition of chymotrypsin by a complex of ortho-vanadate and benzohydroxamic Acid: structure of the inert complex and its mechanistic interpretation.
Biochemistry, 46, 2007
3TGJ
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S195A TRYPSINOGEN COMPLEXED WITH BOVINE PANCREATIC TRYPSIN INHIBITOR (BPTI)
分子名称: BOVINE PANCREATIC TRYPSIN INHIBITOR, CALCIUM ION, SULFATE ION, ...
著者Pasternak, A, Ringe, D, Hedstrom, L.
登録日1998-07-16
公開日1998-12-23
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Comparison of Anionic and Cationic Trypsinogens: The Anionic Activation Domain is More Flexible in Solution and Differs in its Mode of Bpti Binding in the Crystal Structure
Protein Sci., 8, 1999
3B35
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Crystal structure of the M180A mutant of the aminopeptidase from Vibrio proteolyticus
分子名称: Bacterial leucyl aminopeptidase, SODIUM ION, THIOCYANATE ION, ...
著者Ataie, N.J, Hoang, Q.Q, Petsko, G.A, Ringe, D.
登録日2007-10-19
公開日2007-11-27
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Zinc coordination geometry and ligand binding affinity: the structural and kinetic analysis of the second-shell serine 228 residue and the methionine 180 residue of the aminopeptidase from Vibrio proteolyticus.
Biochemistry, 47, 2008
1DAA
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CRYSTALLOGRAPHIC STRUCTURE OF D-AMINO ACID AMINOTRANSFERASE COMPLEXED WITH PYRIDOXAL-5'-PHOSPHATE
分子名称: D-AMINO ACID AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE
著者Sugio, S, Peisach, D, Ringe, D.
登録日1995-06-09
公開日1995-09-15
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Crystal structure of a D-amino acid aminotransferase: how the protein controls stereoselectivity.
Biochemistry, 34, 1995
5R42
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Crystal Structure of deuterated gamma-Chymotrypsin at pH 7.5, room temperature
分子名称: IODIDE ION, gamma-Chymotrypsin, peptide SWPW, ...
著者Kreinbring, C.A, Wilson, M.A, Kovalevsky, A.Y, Blakeley, M.P, Fisher, S.Z, Lazar, L.M, Moulin, A.G, Novak, W.R, Petsko, G.A, Ringe, D.
登録日2020-02-18
公開日2021-09-01
実験手法X-RAY DIFFRACTION (1.05 Å)
主引用文献Effect of Temperature and pH on Ionizable Residues in gamma-Chymotrypsin: a X-ray and Neutron Crystallography Study
To be published
5R49
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Crystal Structure of gamma-Chymotrypsin at pH 5.6, cryo temperature
分子名称: IODIDE ION, MALONATE ION, gamma-chymotrypsin, ...
著者Kreinbring, C.A, Wilson, M.A, Kovalevsky, A.Y, Blakeley, M.P, Fisher, S.Z, Lazar, L.M, Moulin, A.G, Novak, W.R, Petsko, G.A, Ringe, D.
登録日2020-02-18
公開日2021-09-01
実験手法X-RAY DIFFRACTION (1.05 Å)
主引用文献Effect of Temperature and pH on Ionizable Residues in gamma-Chymotrypsin: a X-ray and Neutron Crystallography Study
To be published
5R45
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Crystal Structure of gamma-Chymotrypsin at pH 7.5, cryo temperature
分子名称: Chymotrypsinogen A, IODIDE ION, MALONATE ION, ...
著者Kreinbring, C.A, Wilson, M.A, Kovalevsky, A.Y, Blakeley, M.P, Fisher, S.Z, Lazar, L.M, Moulin, A.G, Novak, W.R, Petsko, G.A, Ringe, D.
登録日2020-02-18
公開日2021-09-01
実験手法X-RAY DIFFRACTION (1.05 Å)
主引用文献Effect of Temperature and pH on Ionizable Residues in gamma-Chymotrypsin: a X-ray and Neutron Crystallography Study
To be published

224004

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