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PDB: 50 件

3MNR
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BU of 3mnr by Molmil
Crystal Structure of Benzamide SNX-1321 bound to Hsp90
分子名称: 2-[(3,4,5-trimethoxyphenyl)amino]-4-(2,6,6-trimethyl-4-oxo-4,5,6,7-tetrahydro-1H-indol-1-yl)benzamide, Heat shock protein HSP 90-alpha
著者Veal, J.M, Fadden, P, Huang, K.H, Rice, J, Hall, S.E, Haytstead, T.A.
登録日2010-04-22
公開日2010-08-11
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Application of Chemoproteomics to Drug Discovery: Identification of a Clinical Candidate Targeting Hsp90.
Chem.Biol., 17, 2010
1BPS
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BU of 1bps by Molmil
MINOR CONFORMER OF A BENZO[A]PYRENE DIOL EPOXIDE ADDUCT OF DA IN DUPLEX DNA
分子名称: 1,2,3-TRIHYDROXY-1,2,3,4-TETRAHYDROBENZO[A]PYRENE, DNA (5'-D(*CP*TP*CP*GP*GP*GP*AP*CP*C)-3'), DNA (5'-D(*GP*GP*TP*CP*(BAP)AP*CP*GP*AP*G)-3')
著者Schwartz, J.S, Rice, J.S, Luxon, B.A, Sayer, J.M, Xie, G, Yeh, H.J.C, Liu, X, Jerina, D.M, Gorenstein, D.G.
登録日1998-08-06
公開日1998-08-19
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Solution structure of the minor conformer of a DNA duplex containing a dG mismatch opposite a benzo[a]pyrene diol epoxide/dA adduct: glycosidic rotation from syn to anti at the modified deoxyadenosine.
Biochemistry, 36, 1997
1N8C
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BU of 1n8c by Molmil
Solution Structure of a Cis-Opened (10R)-N6-Deoxyadenosine Adduct of (9S,10R)-(9,10)-Epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene in a DNA Duplex
分子名称: (9S,10R)-9-HYDROXY-7,8,9,10-TETRAHYDROBENZO[A]PYRENE, 5'-D(*CP*CP*TP*CP*GP*TP*GP*AP*CP*CP*G)-3', 5'-D(*CP*GP*GP*TP*CP*AP*CP*GP*AP*GP*G)-3'
著者Volk, D.E, Thiviyanathan, V, Rice, J.S, Luxon, B.A, Shah, J.H, Yagi, H, Sayer, J.M, Yeh, H.J.C, Jerina, D.M, Gorenstein, D.G.
登録日2002-11-20
公開日2003-02-14
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution Structure of a Cis-Opened (10R)-N6-Deoxyadenosine Adduct of (9S,10R)-(9,10)-Epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene in a DNA Duplex
Biochemistry, 42, 2003
1YWV
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BU of 1ywv by Molmil
Crystal Structures of Proto-Oncogene Kinase Pim1: a Target of Aberrant Somatic Hypermutations in Diffuse Large Cell Lymphoma
分子名称: IMIDAZOLE, Proto-oncogene serine/threonine-protein kinase Pim-1
著者Kumar, A, Mandiyan, V, Suzuki, Y, Zhang, C, Rice, J, Tsai, J, Artis, D.R, Ibrahim, P, Bremer, R.
登録日2005-02-18
公開日2005-04-26
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structures of proto-oncogene kinase Pim1: a target of aberrant somatic hypermutations in diffuse large cell lymphoma.
J.Mol.Biol., 348, 2005
1YXV
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BU of 1yxv by Molmil
Crystal Structure of Kinase Pim1 in complex with 3,4-Dihydroxy-1-methylquinolin-2(1H)-one
分子名称: 3,4-DIHYDROXY-1-METHYLQUINOLIN-2(1H)-ONE, IMIDAZOLE, Proto-oncogene serine/threonine-protein kinase Pim-1
著者Kumar, A, Mandiyan, V, Suzuki, Y, Zhang, C, Rice, J, Tsai, J, Artis, D.R, Ibrahim, P, Bremer, R.
登録日2005-02-22
公開日2005-04-26
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structures of Proto-oncogene Kinase Pim1: A Target of Aberrant Somatic Hypermutations in Diffuse Large Cell Lymphoma.
J.Mol.Biol., 348, 2005
1YXS
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BU of 1yxs by Molmil
Crystal Structure of Kinase Pim1 with P123M mutation
分子名称: IMIDAZOLE, Proto-oncogene serine/threonine-protein kinase Pim-1
著者Kumar, A, Mandiyan, V, Suzuki, Y, Zhang, C, Rice, J, Tsai, J, Artis, D.R, Ibrahim, P, Bremer, R.
登録日2005-02-22
公開日2005-04-26
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structures of proto-oncogene kinase Pim1: a target of aberrant somatic hypermutations in diffuse large cell lymphoma.
J.Mol.Biol., 348, 2005
1YXT
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BU of 1yxt by Molmil
Crystal Structure of Kinase Pim1 in complex with AMPPNP
分子名称: PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Proto-oncogene serine/threonine-protein kinase Pim-1
著者Kumar, A, Mandiyan, V, Suzuki, Y, Zhang, C, Rice, J, Tsai, J, Artis, D.R, Ibrahim, P, Bremer, R.
登録日2005-02-22
公開日2005-04-26
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structures of proto-oncogene kinase Pim1: a target of aberrant somatic hypermutations in diffuse large cell lymphoma.
J.Mol.Biol., 348, 2005
1YXU
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BU of 1yxu by Molmil
Crystal Structure of Kinase Pim1 in Complex with AMP
分子名称: ADENOSINE MONOPHOSPHATE, IMIDAZOLE, Proto-oncogene serine/threonine-protein kinase Pim-1
著者Kumar, A, Mandiyan, V, Suzuki, Y, Zhang, C, Rice, J, Tsai, J, Artis, D.R, Ibrahim, P, Bremer, R.
登録日2005-02-22
公開日2005-04-26
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Crystal Structures of Proto-oncogene Kinase Pim1: A Target of Aberrant Somatic Hypermutations in Diffuse Large Cell Lymphoma.
J.Mol.Biol., 348, 2005
1YXX
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BU of 1yxx by Molmil
Crystal Structure of Kinase Pim1 in complex with (3E)-3-[(4-HYDROXYPHENYL)IMINO]-1H-INDOL-2(3H)-ONE
分子名称: (3E)-3-[(4-HYDROXYPHENYL)IMINO]-1H-INDOL-2(3H)-ONE, IMIDAZOLE, Proto-oncogene serine/threonine-protein kinase Pim-1
著者Kumar, A, Mandiyan, V, Suzuki, Y, Zhang, C, Rice, J, Tsai, J, Artis, D.R, Ibrahim, P, Bremer, R.
登録日2005-02-22
公開日2005-04-26
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structures of proto-oncogene kinase Pim1: a target of aberrant somatic hypermutations in diffuse large cell lymphoma.
J.Mol.Biol., 348, 2005
1AC3
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BU of 1ac3 by Molmil
SOLUTION STRUCTURE OF AN RNA-DNA HYBRID DUPLEX CONTAINING A 3'-THIOFORMACETAL LINKER AND AN RNA A-TRACT, NMR, 8 STRUCTURES
分子名称: ANTISENSE HYBRID DUPLEX, DNA (5'-D(*(TCP)P*TP*GP*CP*GP*C)-3')
著者Cross, C.W, Rice, J.S, Gao, X.
登録日1997-02-11
公開日1997-06-16
最終更新日2024-04-10
実験手法SOLUTION NMR
主引用文献Solution structure of an RNA x DNA hybrid duplex containing a 3'-thioformacetal linker and an RNA A-tract.
Biochemistry, 36, 1997
1FYY
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BU of 1fyy by Molmil
HPRT GENE MUTATION HOTSPOT WITH A BPDE2(10R) ADDUCT
分子名称: 1,2,3-TRIHYDROXY-1,2,3,4-TETRAHYDROBENZO[A]PYRENE, 5'-D(*TP*GP*CP*CP*CP*TP*TP*GP*AP*CP*TP*A)-3', HPRT DNA WITH BENZO[A]PYRENE-ADDUCTED DA7
著者Volk, D.E, Rice, J.S, Luxon, B.A, Yeh, H.J.C, Liang, C, Xie, G, Sayer, J.M, Jerina, D.M, Gorenstein, D.G.
登録日2000-10-03
公開日2000-12-06
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献NMR evidence for syn-anti interconversion of a trans opened (10R)-dA adduct of benzo[a]pyrene (7S,8R)-diol (9R,10S)-epoxide in a DNA duplex.
Biochemistry, 39, 2000
6Q1W
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BU of 6q1w by Molmil
Coiled-coil Trimer with Glu:Val:Lys Triad
分子名称: Coiled-coil Trimer with Glu:Val:Lys Triad
著者Smith, M.S, Stern, K.L, Billings, W.M, Price, J.L.
登録日2019-08-06
公開日2020-04-29
最終更新日2020-05-20
実験手法X-RAY DIFFRACTION (1.498 Å)
主引用文献Context-Dependent Stabilizing Interactions among Solvent-Exposed Residues along the Surface of a Trimeric Helix Bundle.
Biochemistry, 59, 2020
7PD3
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BU of 7pd3 by Molmil
Structure of the human mitoribosomal large subunit in complex with NSUN4.MTERF4.GTPBP7 and MALSU1.L0R8F8.mt-ACP
分子名称: 16S rRNA, 39S ribosomal protein L10, mitochondrial, ...
著者Chandrasekaran, V, Desai, N, Burton, N.O, Yang, H, Price, J, Miska, E.A, Ramakrishnan, V.
登録日2021-08-04
公開日2021-11-17
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Visualizing formation of the active site in the mitochondrial ribosome.
Elife, 10, 2021
6OMB
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BU of 6omb by Molmil
Cdc48 Hexamer (Subunits A to E) with substrate bound to the central pore
分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Cell division control protein 48, ...
著者Cooney, I, Han, H, Stewart, M, Carson, R.H, Hansen, D, Price, J.C, Hill, C.P, Shen, P.S.
登録日2019-04-18
公開日2019-07-17
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structure of the Cdc48 segregase in the act of unfolding an authentic substrate.
Science, 365, 2019
6OPC
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BU of 6opc by Molmil
Cdc48 Hexamer in a complex with substrate and Shp1(Ubx Domain)
分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Cell division control protein 48, ...
著者Cooney, I, Han, H, Stewart, M, Carson, R.H, Hansen, D, Price, J.C, Hill, C.P, Shen, P.S.
登録日2019-04-24
公開日2019-07-10
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structure of the Cdc48 segregase in the act of unfolding an authentic substrate.
Science, 365, 2019
6O2E
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BU of 6o2e by Molmil
GCN4 with asparagine at position 18
分子名称: General control protein GCN4
著者Draper, S.R.E, Xiao, Q, Smith, M, Price, J.L.
登録日2019-02-22
公開日2019-06-26
最終更新日2019-12-18
実験手法X-RAY DIFFRACTION (1.896 Å)
主引用文献Influence of PEGylation on the Strength of Protein Surface Salt Bridges.
Acs Chem.Biol., 14, 2019
6O2F
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BU of 6o2f by Molmil
GCN4 with NPEG4 at position 18
分子名称: General control protein GCN4
著者Draper, S.R.E, Xiao, Q, Smith, M, Price, J.L.
登録日2019-02-22
公開日2019-06-26
最終更新日2019-12-18
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Influence of PEGylation on the Strength of Protein Surface Salt Bridges.
Acs Chem.Biol., 14, 2019
6OVU
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BU of 6ovu by Molmil
Coiled-coil Trimer with Glu:3,4-difluorophenylalanine:Lys Triad
分子名称: Coiled-coil Trimer with Glu:3,4-difluorophenylalanine:Lys Triad
著者Smith, M.S, Stern, K.L, Billings, W.M, Price, J.L.
登録日2019-05-08
公開日2020-04-29
最終更新日2020-05-20
実験手法X-RAY DIFFRACTION (2.101 Å)
主引用文献Context-Dependent Stabilizing Interactions among Solvent-Exposed Residues along the Surface of a Trimeric Helix Bundle.
Biochemistry, 59, 2020
6Q22
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BU of 6q22 by Molmil
Coiled-coil Trimer with Glu:Aminobutyric acid:Lys Triad
分子名称: Coiled-coil Trimer with Glu:Aminobutyric acid:Lys Triad, PENTAETHYLENE GLYCOL
著者Smith, M.S, Stern, K.L, Billings, W.M, Price, J.L.
登録日2019-08-06
公開日2020-04-29
最終更新日2020-05-20
実験手法X-RAY DIFFRACTION (1.599 Å)
主引用文献Context-Dependent Stabilizing Interactions among Solvent-Exposed Residues along the Surface of a Trimeric Helix Bundle.
Biochemistry, 59, 2020
6Q25
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BU of 6q25 by Molmil
Coiled-coil Trimer with Glu:Leu:Lys Triad
分子名称: Coiled-coil Trimer with Glu:Leu:Lys Triad
著者Smith, M.S, Stern, K.L, Billings, W.M, Price, J.L.
登録日2019-08-06
公開日2020-04-29
最終更新日2020-05-20
実験手法X-RAY DIFFRACTION (1.893 Å)
主引用文献Context-Dependent Stabilizing Interactions among Solvent-Exposed Residues along the Surface of a Trimeric Helix Bundle.
Biochemistry, 59, 2020
6OV9
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BU of 6ov9 by Molmil
Coiled-coil Trimer with Glu:p-nitrophenylalanine:Lys Triad
分子名称: Coiled-coil Trimer with Glu:p-nitrophenylalanine:Lys Triad
著者Smith, M.S, Stern, K.L, Billings, W.M, Price, J.L.
登録日2019-05-07
公開日2020-04-29
最終更新日2020-05-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Context-Dependent Stabilizing Interactions among Solvent-Exposed Residues along the Surface of a Trimeric Helix Bundle.
Biochemistry, 59, 2020
6OSD
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BU of 6osd by Molmil
Coiled-coil Trimer with Glu:Phe:Lys Triad
分子名称: Coiled-coil Trimer with Glu:Phe:Lys Triad
著者Smith, M.S, Stern, K.L, Billings, W.M, Price, J.L.
登録日2019-05-01
公開日2020-04-29
最終更新日2020-05-20
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Context-Dependent Stabilizing Interactions among Solvent-Exposed Residues along the Surface of a Trimeric Helix Bundle.
Biochemistry, 59, 2020
6OVS
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BU of 6ovs by Molmil
Coiled-coil Trimer with Glu:Tyr:Lys Triad
分子名称: Coiled-coil Trimer with Glu:Tyr:Lys Triad, PENTAETHYLENE GLYCOL
著者Smith, M.S, Stern, K.L, Billings, W.M, Price, J.L.
登録日2019-05-08
公開日2020-04-29
最終更新日2020-05-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Context-Dependent Stabilizing Interactions among Solvent-Exposed Residues along the Surface of a Trimeric Helix Bundle.
Biochemistry, 59, 2020
6OS8
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BU of 6os8 by Molmil
Coiled-coil Trimer with Glu:p-fluorophenylalanine:Lys Triad
分子名称: Coiled-coil trimer with Glu:p-fluorophenylalanine:Lys Triad
著者Smith, M.S, Stern, K.L, Billings, W.M, Price, J.L.
登録日2019-05-01
公開日2020-04-29
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Context-Dependent Stabilizing Interactions among Solvent-Exposed Residues along the Surface of a Trimeric Helix Bundle.
Biochemistry, 59, 2020
6OVV
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BU of 6ovv by Molmil
Coiled-coil Trimer with Glu:4-pyridinylalanine:Lys Triad
分子名称: Coiled-coil Trimer with Glu:4-pyridinylalanine:Lys Triad
著者Smith, M.S, Stern, K.L, Billings, W.M, Price, J.L.
登録日2019-05-08
公開日2020-04-29
最終更新日2020-05-20
実験手法X-RAY DIFFRACTION (2.201 Å)
主引用文献Context-Dependent Stabilizing Interactions among Solvent-Exposed Residues along the Surface of a Trimeric Helix Bundle.
Biochemistry, 59, 2020

 

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