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PDB: 18 results
9BHB
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BU of 9bhb by Molmil
Cryo-EM structure of human monoclonal antibody C74 targeting PFD1235w (CIDRa1.6) PfEMP1
Descriptor: C74 heavy chain, C74 kappa chain, Erythrocyte membrane protein 1, ...
Authors:Raghavan, S.S.R, Ward, A.B.
Deposit date:2024-04-19
Release date:2024-10-02
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Cryo-EM structure of human monoclonal C74 targeting CIDRa1.6 PfEMP1 malarial protein
To Be Published
8P2E
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BU of 8p2e by Molmil
Homotypic interacting B1 fab bound to Chondroitin Sulfate A
Descriptor: B1 fab heavy, B1 fab light
Authors:Raghavan, S.S.R, Dagil, R, Wang, K.T, Salanti, A.
Deposit date:2023-05-16
Release date:2024-06-05
Last modified:2024-09-11
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Tumor-agnostic cancer therapy using antibodies targeting oncofetal chondroitin sulfate.
Nat Commun, 15, 2024
8C3Y
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BU of 8c3y by Molmil
HB3VAR03 apo headstructure (PfEMP1 A)
Descriptor: PfEMP1
Authors:Raghavan, S.S.R, Lavstsen, T, Wang, K.T.
Deposit date:2022-12-29
Release date:2023-08-02
Last modified:2024-10-09
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Endothelial protein C receptor binding induces conformational changes to severe malaria-associated group A PfEMP1.
Structure, 31, 2023
8C44
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BU of 8c44 by Molmil
HB3VAR03 apo headstructure (PfEMP1 A) complexed with EPCR
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Endothelial protein C receptor, PHOSPHATIDYLETHANOLAMINE, ...
Authors:Raghavan, S.S.R, Lavstsen, T, Wang, K.T.
Deposit date:2022-12-31
Release date:2023-08-16
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Endothelial protein C receptor binding induces conformational changes to severe malaria-associated group A PfEMP1.
Structure, 31, 2023
7Z1H
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BU of 7z1h by Molmil
VAR2CSA APO
Descriptor: VAR2CSA APO
Authors:Raghavan, S.S.R, Wang, K.T.
Deposit date:2022-02-24
Release date:2022-11-02
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (3.12 Å)
Cite:Cryo-EM reveals the conformational epitope of human monoclonal antibody PAM1.4 broadly reacting with polymorphic malarial protein VAR2CSA.
Plos Pathog., 18, 2022
7Z12
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BU of 7z12 by Molmil
VAR2 complex with PAM1.4
Descriptor: PAM1.4, Heavy Chain, light Chain, ...
Authors:Raghavan, S.S.R, Wang, K.T.
Deposit date:2022-02-24
Release date:2022-11-02
Last modified:2022-11-30
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Cryo-EM reveals the conformational epitope of human monoclonal antibody PAM1.4 broadly reacting with polymorphic malarial protein VAR2CSA.
Plos Pathog., 18, 2022
8VDF
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BU of 8vdf by Molmil
Cryo-EM structure of human monoclonal antibody C7 targeting IT4VAR22 CIDRa1.7 (PfEMP1 A)
Descriptor: C7 Fab heavy chain, C7 Fab lamda chain, Erythrocyte membrane protein 1
Authors:Raghavan, S.S.R, Ward, A.B.
Deposit date:2023-12-15
Release date:2024-10-02
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Cryo-EM structure human monoclonal antibody C7 targeting IT4VAR22 CIDRa1.7
To Be Published
8VDG
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BU of 8vdg by Molmil
Cryo-EM structure of human monoclonal antibody C74 targeting IT4VAR22 CIDRa1.7
Descriptor: C74 Fab heavy chain, C74 Fab kappa chain, Erythrocyte membrane protein 1
Authors:Raghavan, S.S.R, Ward, A.B.
Deposit date:2023-12-15
Release date:2024-10-02
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (3.35 Å)
Cite:Cryo-EM structure of human monoclonal antibody C74 targeting IT4VAR22 CIDRa1.7
To Be Published
8C5R
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BU of 8c5r by Molmil
Omicron B.1.1.529 2 RBD up conformation
Descriptor: Spike glycoprotein
Authors:Raghavan, S.S.R, Walker, M.R, Salanti, A, Barfod, L.K, Wang, K.T.
Deposit date:2023-01-10
Release date:2024-01-24
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Omicron B.1.1.529 2 RBD up conformation
To Be Published
1FAC
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BU of 1fac by Molmil
COAGULATION FACTOR VIII, NMR, 1 STRUCTURE
Descriptor: COAGULATION FACTOR VIII
Authors:Veeraraghavan, S, Baleja, J.D, Gilbert, G.E.
Deposit date:1996-06-30
Release date:1997-01-11
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structure and topography of the membrane-binding C2 domain of factor VIII in the presence of dodecylphosphocholine micelles.
Biochem.J., 332, 1998
1DBD
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BU of 1dbd by Molmil
E2 DNA-BINDING DOMAIN FROM PAPILLOMAVIRUS BPV-1
Descriptor: REGULATORY PROTEIN E2
Authors:Veeraraghavan, S, Mello, C.C, Androphy, E.J, Baleja, J.D.
Deposit date:1999-05-21
Release date:2000-01-01
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Structural correlates for enhanced stability in the E2 DNA-binding domain from bovine papillomavirus.
Biochemistry, 38, 1999
294D
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BU of 294d by Molmil
INTERCALATED CYTOSINE MOTIF AND NOVEL ADENINE CLUSTERS IN THE CRYSTAL STRUCTURE OF TETRAHYMENA TELOMERE
Descriptor: DNA (5'-D(*AP*AP*CP*CP*CP*C)-3')
Authors:Cai, L, Chen, L, Raghavan, S, Ratliff, R, Moyzis, R, Rich, A.
Deposit date:1996-10-30
Release date:1998-10-19
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Intercalated cytosine motif and novel adenine clusters in the crystal structure of the Tetrahymena telomere.
Nucleic Acids Res., 26, 1998
9FJK
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BU of 9fjk by Molmil
Omicron BA.1 Spike protein with neutralizing NTD specific mAb K501SP6
Descriptor: K501SP6 Fv Heavy Chain, K501SP6 Fv Light Chain, Spike glycoprotein,Fibritin
Authors:Bjoernsson, K.H, Walker, M.R, Raghavan, S.S.R, Ward, A.B, Barfod, L.K.
Deposit date:2024-05-31
Release date:2024-08-14
Method:ELECTRON MICROSCOPY (2.84 Å)
Cite:Omicron BA.1 Spike protein with neutralizing NTD specific mAb K501SP6
To Be Published
7D9K
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BU of 7d9k by Molmil
DNA binding domain of human DNA Ligase IV - Wild type
Descriptor: DNA ligase 4
Authors:Maddi, E.R, Raghavan, S.C, Natesh, R.
Deposit date:2020-10-13
Release date:2021-02-24
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Hypomorphic mutations in human DNA ligase IV lead to compromised DNA binding efficiency, hydrophobicity and thermal stability.
Protein Eng.Des.Sel., 34, 2021
7D9Y
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BU of 7d9y by Molmil
DNA binding domain of human DNA Ligase IV mutant - A3V
Descriptor: DNA ligase 4
Authors:Maddi, E.R, Raghavan, S.C, Natesh, R.
Deposit date:2020-10-14
Release date:2021-02-24
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.76 Å)
Cite:Hypomorphic mutations in human DNA ligase IV lead to compromised DNA binding efficiency, hydrophobicity and thermal stability.
Protein Eng.Des.Sel., 34, 2021
8U1S
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BU of 8u1s by Molmil
A mechanistic understanding of protective influenza B neuraminidase mAbs at the airway interface
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Neuraminidase, mAb-393 heavy chain, ...
Authors:Ferguson, J.A, Raghavan, S.S.R, Ward, A.B.
Deposit date:2023-09-02
Release date:2024-03-27
Method:ELECTRON MICROSCOPY (3.21 Å)
Cite:A mechanistic understanding of protective influenza B neuraminidase mAbs at the airway interface
To Be Published
2HZD
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BU of 2hzd by Molmil
NMR structure of the DNA-binding TEA domain and insights into TEF-1 function
Descriptor: Transcriptional enhancer factor TEF-1
Authors:Anbanandam, A, Veeraraghavan, S.
Deposit date:2006-08-08
Release date:2006-10-24
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Insights into transcription enhancer factor 1 (TEF-1) activity from the solution structure of the TEA domain.
Proc.Natl.Acad.Sci.Usa, 103, 2006
4Z8E
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BU of 4z8e by Molmil
TEAD DBD mutant -deltaL1
Descriptor: Transcriptional enhancer factor TEF-1
Authors:Lee, D.-S, Albarado, D.C, Vonrhein, C, Raman, C.S, Veeraraghavan, S.
Deposit date:2015-04-08
Release date:2016-04-13
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.092 Å)
Cite:A Potential Structural Switch for Regulating DNA-Binding by TEAD Transcription Factors.
J.Mol.Biol., 428, 2016

226707

数据于2024-10-30公开中

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