6KLB
| Structure of LbCas12a-crRNA complex bound to AcrVA4 (form B complex) | 分子名称: | AcrVA4, LbCas12a, MAGNESIUM ION, ... | 著者 | Peng, R, Li, Z, Xu, Y, He, S, Peng, Q, Shi, Y, Gao, G.F. | 登録日 | 2019-07-30 | 公開日 | 2019-09-11 | 最終更新日 | 2019-11-06 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Structural insight into multistage inhibition of CRISPR-Cas12a by AcrVA4. Proc.Natl.Acad.Sci.USA, 116, 2019
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6QW5
| Structure and function of the toscana virus cap snatching endonuclease | 分子名称: | 2-4-DIOXO-4-PHENYLBUTANOIC ACID, MANGANESE (II) ION, RNA-dependent RNA polymerase, ... | 著者 | Reguera, J, Jones, R, Bragagniolo, G, Lessoued, S, Mate, M. | 登録日 | 2019-03-05 | 公開日 | 2019-09-25 | 最終更新日 | 2019-11-20 | 実験手法 | X-RAY DIFFRACTION (1.988 Å) | 主引用文献 | Structure and function of the Toscana virus cap-snatching endonuclease. Nucleic Acids Res., 47, 2019
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6QLO
| Galectin-3C in complex with substituted fluoroaryltriazole monothiogalactoside derivative 1 | 分子名称: | (2~{R},3~{R},4~{S},5~{R},6~{S})-4-[4-[3,4-bis(fluoranyl)phenyl]-1,2,3-triazol-1-yl]-2-(hydroxymethyl)-6-(4-methylphenyl)sulfanyl-oxane-3,5-diol, CHLORIDE ION, Galectin-3 | 著者 | Kumar, R, Peterson, K, Nilsson, U.J, Logan, D.T. | 登録日 | 2019-02-01 | 公開日 | 2019-07-10 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.18 Å) | 主引用文献 | Structure and Energetics of Ligand-Fluorine Interactions with Galectin-3 Backbone and Side-Chain Amides: Insight into Solvation Effects and Multipolar Interactions. Chemmedchem, 14, 2019
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6QLQ
| Galectin-3C in complex with fluoroaryltriazole monothiogalactoside derivative 4 | 分子名称: | (2~{R},3~{R},4~{S},5~{R},6~{S})-4-[4-(4-fluorophenyl)-1,2,3-triazol-1-yl]-2-(hydroxymethyl)-6-(4-methylphenyl)sulfanyl-oxane-3,5-diol, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | 著者 | Kumar, R, Peterson, K, Nilsson, U.J, Logan, D.T. | 登録日 | 2019-02-01 | 公開日 | 2019-07-10 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.079 Å) | 主引用文献 | Structure and Energetics of Ligand-Fluorine Interactions with Galectin-3 Backbone and Side-Chain Amides: Insight into Solvation Effects and Multipolar Interactions. Chemmedchem, 14, 2019
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6QXM
| Cryo-EM structure of T7 bacteriophage portal protein, 12mer, open valve | 分子名称: | Portal protein | 著者 | Fabrega-Ferrer, M, Cuervo, A, Machon, C, Fernandez, F.J, Perez-Luque, R, Pous, J, Vega, M.C, Carrascosa, J.L, Coll, M. | 登録日 | 2019-03-07 | 公開日 | 2019-09-04 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Structures of T7 bacteriophage portal and tail suggest a viral DNA retention and ejection mechanism. Nat Commun, 10, 2019
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6KN4
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6QP1
| Crystal structure of the PLP-bound C-S lyase in the external aldimine form from Staphylococcus hominis complexed with an inhibitor, L-cycloserine. | 分子名称: | Aminotransferase, [5-hydroxy-6-methyl-4-({[(4E)-3-oxo-1,2-oxazolidin-4-ylidene]amino}methyl)pyridin-3-yl]methyl dihydrogen phosphate | 著者 | Herman, R, Rudden, M, Wilkinson, A.J, Hanai, S, Thomas, G.H. | 登録日 | 2019-02-13 | 公開日 | 2020-03-04 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.42 Å) | 主引用文献 | The molecular basis of thioalcohol production in human body odour. Sci Rep, 10, 2020
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6QPA
| Halothiobacillus neapolitanus sulfur oxygenase reductase | 分子名称: | FE (III) ION, SULFATE ION, Sulfur oxygenase/reductase | 著者 | Frazao, C, Klezin, A, Poell, U, Veith, A, Ruehl, P, Coelho, R. | 登録日 | 2019-02-13 | 公開日 | 2020-03-18 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Multiple sulfane modifications in active-site cysteine thiols of two sulfur oxygenase reductases and analysis of substrate/product channels To Be Published
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6QM9
| Cryo-EM structure of calcium-bound nhTMEM16 lipid scramblase in nanodisc (open state) | 分子名称: | CALCIUM ION, Predicted protein | 著者 | Kalienkova, V, Clerico Mosina, V, Bryner, L, Oostergetel, G.T, Dutzler, R, Paulino, C. | 登録日 | 2019-02-01 | 公開日 | 2019-03-06 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Stepwise activation mechanism of the scramblase nhTMEM16 revealed by cryo-EM. Elife, 8, 2019
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6JXU
| SUMO1 bound to SLS4-SIM peptide from ICP0 | 分子名称: | Small ubiquitin-related modifier, viral protein | 著者 | Hembram, D.S.S, Negi, H, Shet, D, Das, R. | 登録日 | 2019-04-25 | 公開日 | 2020-02-05 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | The Viral SUMO-Targeted Ubiquitin Ligase ICP0 is Phosphorylated and Activated by Host Kinase Chk2. J.Mol.Biol., 432, 2020
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6QLR
| Galectin-3C in complex with fluoroaryltriazole monothiogalactoside derivative 5 | 分子名称: | (2~{R},3~{R},4~{S},5~{R},6~{S})-4-[4-[3,5-bis(fluoranyl)phenyl]-1,2,3-triazol-1-yl]-2-(hydroxymethyl)-6-(4-methylphenyl)sulfanyl-oxane-3,5-diol, CHLORIDE ION, Galectin-3 | 著者 | Kumar, R, Peterson, K, Nilsson, U.J, Logan, D.T. | 登録日 | 2019-02-01 | 公開日 | 2019-07-10 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (0.97 Å) | 主引用文献 | Structure and Energetics of Ligand-Fluorine Interactions with Galectin-3 Backbone and Side-Chain Amides: Insight into Solvation Effects and Multipolar Interactions. Chemmedchem, 14, 2019
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6KNA
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6JXV
| SUMO1 bound to phosphorylated SLS4-SIM peptide from ICP0 | 分子名称: | Phosphorylated SLS4-SIM from ubiquitin E3 ligase ICP0, Small ubiquitin-related modifier | 著者 | Hembram, D.S.S, Negi, H, Shet, D, Das, R. | 登録日 | 2019-04-25 | 公開日 | 2020-02-05 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | The Viral SUMO-Targeted Ubiquitin Ligase ICP0 is Phosphorylated and Activated by Host Kinase Chk2. J.Mol.Biol., 432, 2020
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6QM4
| Cryo-EM structure of calcium-free nhTMEM16 lipid scramblase in nanodisc | 分子名称: | Predicted protein | 著者 | Kalienkova, V, Clerico Mosina, V, Bryner, L, Oostergetel, G.T, Dutzler, R, Paulino, C. | 登録日 | 2019-02-01 | 公開日 | 2019-03-06 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Stepwise activation mechanism of the scramblase nhTMEM16 revealed by cryo-EM. Elife, 8, 2019
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6JXW
| Complex of SUMO2 bound SLS4 from ICP0. | 分子名称: | SLS4-SIM from Ubiquitin E3 ligase ICP0, Small ubiquitin-related modifier 2 | 著者 | Hembram, D.S.S, Negi, H, Shet, D, Das, R. | 登録日 | 2019-04-25 | 公開日 | 2020-02-05 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | The Viral SUMO-Targeted Ubiquitin Ligase ICP0 is Phosphorylated and Activated by Host Kinase Chk2. J.Mol.Biol., 432, 2020
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6JXX
| SUMO2 bound to phosphorylated SLS4-SIM peptide from ICP0 | 分子名称: | Phosphorylated SLS4 from E3 ubiquitin ligase ICP0, Small ubiquitin-related modifier 2 | 著者 | Hembram, D.S.S, Negi, H, Shet, D, Das, R. | 登録日 | 2019-04-25 | 公開日 | 2020-02-05 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | The Viral SUMO-Targeted Ubiquitin Ligase ICP0 is Phosphorylated and Activated by Host Kinase Chk2. J.Mol.Biol., 432, 2020
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8SYC
| Crystal structure of PDE3B in complex with GSK4394835A | 分子名称: | MAGNESIUM ION, [3-[(4,7-dimethoxyquinolin-2-yl)carbonylamino]-5-[methyl-(phenylmethyl)carbamoyl]phenyl]-oxidanyl-oxidanylidene-boron, cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B | 著者 | Concha, N.O, Nolte, R. | 登録日 | 2023-05-25 | 公開日 | 2024-02-07 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Discovery and SAR Study of Boronic Acid-Based Selective PDE3B Inhibitors from a Novel DNA-Encoded Library. J.Med.Chem., 67, 2024
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6KPD
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6QVV
| Structure and function of phenuiviridae cap snatching endonucleases | 分子名称: | GLYCEROL, MANGANESE (III) ION, RNA-dependent RNA polymerase, ... | 著者 | Reguera, J, Jones, R, Bragagniolo, G, Lessoued, S, Mate, M. | 登録日 | 2019-03-05 | 公開日 | 2019-09-25 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structure and function of the Toscana virus cap-snatching endonuclease. Nucleic Acids Res., 47, 2019
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6QW0
| Structure and function of toscana virus cap snatching endonucleases | 分子名称: | GLYCEROL, MANGANESE (III) ION, RNA-dependent RNA polymerase, ... | 著者 | Reguera, J, Jones, R, Bragagniolo, G, Lessoued, S, Mate, M. | 登録日 | 2019-03-05 | 公開日 | 2019-09-25 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structure and function of the Toscana virus cap-snatching endonuclease. Nucleic Acids Res., 47, 2019
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6QWP
| Crystal structure of T7 bacteriophage portal protein, 13mer, closed valve | 分子名称: | Portal protein | 著者 | Fabrega-Ferrer, M, Cuervo, A, Machon, C, Fernandez, F.J, Perez-Luque, R, Pous, J, Vega, M.C, Carrascosa, J.L, Coll, M. | 登録日 | 2019-03-06 | 公開日 | 2019-09-04 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Structures of T7 bacteriophage portal and tail suggest a viral DNA retention and ejection mechanism. Nat Commun, 10, 2019
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4U8M
| Structure of Aspergillus fumigatus UDP-Galactopyranose mutase mutant Y317A | 分子名称: | 1,2-ETHANEDIOL, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, SULFATE ION, ... | 著者 | Qureshi, I.A, Chaudhary, R, Tanner, J.J. | 登録日 | 2014-08-03 | 公開日 | 2014-12-03 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Contributions of Unique Active Site Residues of Eukaryotic UDP-Galactopyranose Mutases to Substrate Recognition and Active Site Dynamics. Biochemistry, 53, 2014
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6QZJ
| Crystal structure of human Aquaporin 7 at 2.2 A resolution | 分子名称: | Aquaporin-7, GLYCEROL, PHOSPHATE ION | 著者 | de Mare, S.W.-H, Venskutonyte, R, Eltschkner, S, Lindkvist-Petersson, K. | 登録日 | 2019-03-11 | 公開日 | 2019-11-27 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural Basis for Glycerol Efflux and Selectivity of Human Aquaporin 7. Structure, 28, 2020
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4U8K
| Structure of Aspergillus fumigatus UDP-Galactopyranose mutase mutant Q107A | 分子名称: | 1,2-ETHANEDIOL, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, SULFATE ION, ... | 著者 | Qureshi, I.A, Chaudhary, R, Tanner, J.J. | 登録日 | 2014-08-03 | 公開日 | 2014-12-03 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Contributions of Unique Active Site Residues of Eukaryotic UDP-Galactopyranose Mutases to Substrate Recognition and Active Site Dynamics. Biochemistry, 53, 2014
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6QZN
| H30 MnSOD-3 Mutant III | 分子名称: | MANGANESE (II) ION, SULFATE ION, Superoxide dismutase [Mn] 2, ... | 著者 | Bonetta, R, Trinh, C.H, Hunter, G.J, Hunter, T. | 登録日 | 2019-03-11 | 公開日 | 2020-02-19 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | 主引用文献 | H30 MnSOD-3 Mutant II To Be Published
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