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PDB: 27 件
7UYG
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BU of 7uyg by Molmil
Structure of the first OTU domain from Legionella pneumophila effector protein LotA
分子名称: GLYCEROL, IODIDE ION, LotA
著者Pruneda, J.N.
登録日2022-05-06
公開日2022-12-21
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Mechanism of Lys6 poly-ubiquitin specificity by the L. pneumophila deubiquitinase LotA.
Mol.Cell, 83, 2023
6GZT
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BU of 6gzt by Molmil
Structure of Chlamydia trachomatis effector protein ChlaDUB1 bound to Coenzyme A
分子名称: COENZYME A, Deubiquitinase and deneddylase Dub1, GLYCEROL, ...
著者Pruneda, J.N, Komander, D.
登録日2018-07-05
公開日2018-11-14
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献A Chlamydia effector combining deubiquitination and acetylation activities induces Golgi fragmentation.
Nat Microbiol, 3, 2018
6GZU
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BU of 6gzu by Molmil
Structure of Chlamydia abortus effector protein ChlaDUB
分子名称: Conserved membrane protein, GLYCEROL, ZINC ION
著者Pruneda, J.N, Komander, D.
登録日2018-07-05
公開日2018-11-14
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献A Chlamydia effector combining deubiquitination and acetylation activities induces Golgi fragmentation.
Nat Microbiol, 3, 2018
6GZS
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BU of 6gzs by Molmil
Structure of Chlamydia trachomatis effector protein ChlaDUB1 bound to ubiquitin
分子名称: Deubiquitinase and deneddylase Dub1, GLYCEROL, Polyubiquitin-B, ...
著者Pruneda, J.N, Komander, D.
登録日2018-07-05
公開日2018-11-14
最終更新日2018-12-05
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A Chlamydia effector combining deubiquitination and acetylation activities induces Golgi fragmentation.
Nat Microbiol, 3, 2018
5IFR
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BU of 5ifr by Molmil
Structure of the stable UBE2D3-UbDha conjugate
分子名称: GLYCEROL, Polyubiquitin-B, Ubiquitin-conjugating enzyme E2 D3
著者Pruneda, J.N, Mulder, M.P.C, Witting, K, Ovaa, H, Komander, D.
登録日2016-02-26
公開日2016-05-11
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献A cascading activity-based probe sequentially targets E1-E2-E3 ubiquitin enzymes.
Nat.Chem.Biol., 12, 2016
4BVU
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BU of 4bvu by Molmil
Structure of Shigella effector OspG in complex with host UbcH5c- Ubiquitin conjugate
分子名称: PROTEIN KINASE OSPG, UBIQUITIN, UBIQUITIN-CONJUGATING ENZYME E2 D3
著者Pruneda, J.N, LeTrong, I, Stenkamp, R.E, Klevit, R.E, Brzovic, P.S.
登録日2013-06-28
公開日2014-01-29
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献E2~Ub Conjugates Regulate the Kinase Activity of Shigella Effector Ospg During Pathogenesis.
Embo J., 33, 2014
5JP3
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BU of 5jp3 by Molmil
Structure of Xanthomonas campestris effector protein XopD bound to ubiquitin
分子名称: Polyubiquitin-B, Xanthomonas outer protein D
著者Pruneda, J.N, Komander, D.
登録日2016-05-03
公開日2016-07-27
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献The Molecular Basis for Ubiquitin and Ubiquitin-like Specificities in Bacterial Effector Proteases.
Mol.Cell, 63, 2016
5JP1
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BU of 5jp1 by Molmil
Structure of Xanthomonas campestris effector protein XopD bound to tomato SUMO
分子名称: (4S,5S)-1,2-DITHIANE-4,5-DIOL, MALONATE ION, Small ubiquitin-related modifier, ...
著者Pruneda, J.N, Komander, D.
登録日2016-05-03
公開日2016-07-27
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The Molecular Basis for Ubiquitin and Ubiquitin-like Specificities in Bacterial Effector Proteases.
Mol.Cell, 63, 2016
5HAM
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BU of 5ham by Molmil
Structure of Rickettsia bellii effector protein RickCE
分子名称: RickCE
著者Pruneda, J.N, Komander, D.
登録日2015-12-30
公開日2016-07-27
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The Molecular Basis for Ubiquitin and Ubiquitin-like Specificities in Bacterial Effector Proteases.
Mol.Cell, 63, 2016
5HAF
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BU of 5haf by Molmil
Structure of Salmonella enterica effector protein SseL
分子名称: Deubiquitinase SseL, POTASSIUM ION
著者Pruneda, J.N, Komander, D.
登録日2015-12-30
公開日2016-07-27
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The Molecular Basis for Ubiquitin and Ubiquitin-like Specificities in Bacterial Effector Proteases.
Mol.Cell, 63, 2016
5HAG
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BU of 5hag by Molmil
Structure of Chlamydia trachomatis effector protein ChlaDUB1
分子名称: Deubiquitinase and deneddylase Dub1, GLYCEROL
著者Pruneda, J.N, Komander, D.
登録日2015-12-30
公開日2016-07-27
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The Molecular Basis for Ubiquitin and Ubiquitin-like Specificities in Bacterial Effector Proteases.
Mol.Cell, 63, 2016
3UGB
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BU of 3ugb by Molmil
UbcH5c~Ubiquitin Conjugate
分子名称: GLYCEROL, Polyubiquitin-C, Ubiquitin-conjugating enzyme E2 D3
著者Page, R.C, Pruneda, J.N, Klevit, R.E, Misra, S.
登録日2011-11-02
公開日2012-05-16
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural insights into the conformation and oligomerization of E2~ubiquitin conjugates.
Biochemistry, 51, 2012
8ST7
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BU of 8st7 by Molmil
Structure of E3 ligase VsHECT bound to ubiquitin
分子名称: E3 ubiquitin-protein ligase SopA-like catalytic domain-containing protein, Ubiquitin, prop-2-en-1-amine
著者Franklin, T.G, Pruneda, J.N.
登録日2023-05-09
公開日2023-07-12
最終更新日2024-01-03
実験手法X-RAY DIFFRACTION (1.44 Å)
主引用文献Bacterial ligases reveal fundamental principles of polyubiquitin specificity.
Mol.Cell, 83, 2023
8ST9
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BU of 8st9 by Molmil
Structure of E3 ligase NleL bound to ubiquitin
分子名称: E3 ubiquitin-protein ligase SopA, Ubiquitin, prop-2-en-1-amine
著者Franklin, T.G, Pruneda, J.N.
登録日2023-05-09
公開日2023-07-12
最終更新日2024-01-03
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Bacterial ligases reveal fundamental principles of polyubiquitin specificity.
Mol.Cell, 83, 2023
8ST8
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BU of 8st8 by Molmil
Structure of E3 ligase SopA bound to ubiquitin
分子名称: E3 ubiquitin-protein ligase SopA, Ubiquitin, prop-2-en-1-amine
著者Franklin, T.G, Pruneda, J.N.
登録日2023-05-09
公開日2023-07-12
最終更新日2024-01-03
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Bacterial ligases reveal fundamental principles of polyubiquitin specificity.
Mol.Cell, 83, 2023
8SSI
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BU of 8ssi by Molmil
Structure of Burkholderia pseudomallei deubiquitinase TssM in complex with ubiquitin
分子名称: Deubiquitinase TssM, GLYCEROL, Ubiquitin, ...
著者Szczesna, M, Pruneda, J.N, Thurston, T.L.M.
登録日2023-05-08
公開日2024-06-05
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Burkholderia esterase TssM counters RNF213-mediated bacterial ubiquitylation
To Be Published
7UYH
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BU of 7uyh by Molmil
Structure of the first OTU domain from Legionella pneumophila effector protein LotA bound to K6-linked diUb
分子名称: LotA, Ubiquitin
著者Warren, G.D, Pruneda, J.N.
登録日2022-05-06
公開日2022-12-21
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Mechanism of Lys6 poly-ubiquitin specificity by the L. pneumophila deubiquitinase LotA.
Mol.Cell, 83, 2023
3OSS
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BU of 3oss by Molmil
The crystal structure of enterotoxigenic Escherichia coli GspC-GspD complex from the type II secretion system
分子名称: CALCIUM ION, CHLORIDE ION, TYPE 2 SECRETION SYSTEM, ...
著者Korotkov, K.V, Pruneda, J, Hol, W.G.J.
登録日2010-09-09
公開日2011-08-03
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.63 Å)
主引用文献Structural and functional studies on the interaction of GspC and GspD in the type II secretion system.
Plos Pathog., 7, 2011
5OXH
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BU of 5oxh by Molmil
C-terminally retracted ubiquitin T66V/L67N mutant
分子名称: SULFATE ION, Ubiquitin T66V/L67N mutant
著者Gladkova, C, Schubert, A.F, Wagstaff, J.L, Pruneda, J.P, Freund, S.M.V, Komander, D.
登録日2017-09-06
公開日2017-11-22
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.601 Å)
主引用文献An invisible ubiquitin conformation is required for efficient phosphorylation by PINK1.
EMBO J., 36, 2017
6FFA
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BU of 6ffa by Molmil
FMDV Leader protease bound to substrate ISG15
分子名称: GLYCEROL, Lbpro, SULFATE ION, ...
著者Swatek, K.N, Pruneda, J.N, Komander, D.
登録日2018-01-05
公開日2018-02-21
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Irreversible inactivation of ISG15 by a viral leader protease enables alternative infection detection strategies.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6W9R
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BU of 6w9r by Molmil
Crystal structure of an OTU deubiquitinase from Wolbachia pipientis wMel bound to ubiquitin
分子名称: CITRATE ANION, OTU domain-containing protein wMelOTU, Ubiquitin
著者Schubert, A.F, Pruneda, J.N, Komander, D.
登録日2020-03-23
公開日2020-07-01
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Identification and characterization of diverse OTU deubiquitinases in bacteria.
Embo J., 39, 2020
6W9S
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BU of 6w9s by Molmil
Crystal structure of an OTU deubiquitinase from Escherichia albertii bound to ubiquitin
分子名称: FORMIC ACID, OTU domain-containing protein EschOTU, Ubiquitin
著者Schubert, A.F, Pruneda, J.N, Komander, D.
登録日2020-03-23
公開日2020-07-01
最終更新日2020-08-12
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Identification and characterization of diverse OTU deubiquitinases in bacteria.
Embo J., 39, 2020
5OXI
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BU of 5oxi by Molmil
C-terminally retracted ubiquitin L67S mutant
分子名称: SULFATE ION, Ubiquitin L67S mutant
著者Gladkova, C.G, Schubert, A.F, Wagstaff, J.L, Pruneda, J.N, Freund, S.M.V, Komander, D.
登録日2017-09-06
公開日2017-11-22
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献An invisible ubiquitin conformation is required for efficient phosphorylation by PINK1.
EMBO J., 36, 2017
6W9O
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BU of 6w9o by Molmil
Crystal structure of an OTU deubiquitinase from Wolbachia pipientis wMel
分子名称: ACETATE ION, OTU domain-containing protein wMelOTU
著者Schubert, A.F, Pruneda, J.N, Komander, D.
登録日2020-03-23
公開日2020-07-01
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献Identification and characterization of diverse OTU deubiquitinases in bacteria.
Embo J., 39, 2020
5AF6
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BU of 5af6 by Molmil
Structure of Lys33-linked diUb bound to Trabid NZF1
分子名称: TRABID, UBIQUITIN, ZINC ION
著者Michel, M.A, Elliott, P.R, Swatek, K.N, Simicek, M, Pruneda, J.N, Wagstaff, J.L, Freund, S.M.V, Komander, D.
登録日2015-01-19
公開日2015-03-25
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Assembly and Specific Recognition of K29- and K33-Linked Polyubiquitin.
Mol.Cell, 58, 2015

 

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