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5MDI
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Crystal structure of TDP-43 N-terminal domain at 2.1 A resolution
Descriptor: ACETATE ION, TAR DNA-binding protein 43
Authors:Afroz, T, Hock, E.-M, Ernst, P, Foglieni, C, Jambeau, M, Gilhespy, L, Laferriere, F, Maniecka, Z, Plueckthun, A, Mittl, P, Paganetti, P, Allain, F.H.T, Polymenidou, M.
Deposit date:2016-11-11
Release date:2017-07-05
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Functional and dynamic polymerization of the ALS-linked protein TDP-43 antagonizes its pathologic aggregation.
Nat Commun, 8, 2017

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