1FWZ
 
 | | GLU20ALA DTXR | | Descriptor: | DIPHTHERIA TOXIN REPRESSOR, SULFATE ION, ZINC ION | | Authors: | Pohl, E, Goranson-Siekierke, J, Holmes, R.K, Hol, W.G.J. | | Deposit date: | 2000-09-25 | | Release date: | 2001-09-25 | | Last modified: | 2021-11-03 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structures of three diphtheria toxin repressor (DtxR) variants with decreased repressor activity.
Acta Crystallogr.,Sect.D, 57, 2001
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1G3T
 | | CYS102SER DTXR | | Descriptor: | DIPHTHERIA TOXIN REPRESSOR | | Authors: | Pohl, E, Goranson-Siekierke, J, Holmes, R.K, Hol, W.G.J. | | Deposit date: | 2000-10-25 | | Release date: | 2001-10-25 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Structures of three diphtheria toxin repressor (DtxR) variants with decreased repressor activity.
Acta Crystallogr.,Sect.D, 57, 2001
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1G3W
 | | CD-CYS102SER DTXR | | Descriptor: | CADMIUM ION, DIPHTHERIA TOXIN REPRESSOR, SULFATE ION | | Authors: | Pohl, E, Goranson-Siekierke, J, Holmes, R.K, Hol, W.G.J. | | Deposit date: | 2000-10-25 | | Release date: | 2001-10-25 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structures of three diphtheria toxin repressor (DtxR) variants with decreased repressor activity.
Acta Crystallogr.,Sect.D, 57, 2001
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1B1B
 | | IRON DEPENDENT REGULATOR | | Descriptor: | PROTEIN (IRON DEPENDENT REGULATOR), SULFATE ION, ZINC ION | | Authors: | Pohl, E, Holmes, R.K, Hol, W.G. | | Deposit date: | 1998-11-19 | | Release date: | 1999-12-03 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Crystal structure of the iron-dependent regulator (IdeR) from Mycobacterium tuberculosis shows both metal binding sites fully occupied.
J.Mol.Biol., 285, 1999
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1BI3
 | | STRUCTURE OF APO-AND HOLO-DIPHTHERIA TOXIN REPRESSOR | | Descriptor: | DIPHTHERIA TOXIN REPRESSOR, SULFATE ION, ZINC ION | | Authors: | Pohl, E, Hol, W.G.J. | | Deposit date: | 1998-06-21 | | Release date: | 1999-06-22 | | Last modified: | 2022-12-21 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Motion of the DNA-binding domain with respect to the core of the diphtheria toxin repressor (DtxR) revealed in the crystal structures of apo- and holo-DtxR.
J.Biol.Chem., 273, 1998
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1BI1
 | | STRUCTURE OF APO-AND HOLO-DIPHTHERIA TOXIN REPRESSOR | | Descriptor: | DIPHTHERIA TOXIN REPRESSOR | | Authors: | Pohl, E, Hol, W.G.J. | | Deposit date: | 1998-06-21 | | Release date: | 1999-06-22 | | Last modified: | 2022-12-21 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Motion of the DNA-binding domain with respect to the core of the diphtheria toxin repressor (DtxR) revealed in the crystal structures of apo- and holo-DtxR.
J.Biol.Chem., 273, 1998
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1BI0
 | | STRUCTURE OF APO-AND HOLO-DIPHTHERIA TOXIN REPRESSOR | | Descriptor: | DIPHTHERIA TOXIN REPRESSOR, SULFATE ION, ZINC ION | | Authors: | Pohl, E, Hol, W.G. | | Deposit date: | 1998-06-21 | | Release date: | 1999-07-22 | | Last modified: | 2022-12-21 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Motion of the DNA-binding domain with respect to the core of the diphtheria toxin repressor (DtxR) revealed in the crystal structures of apo- and holo-DtxR.
J.Biol.Chem., 273, 1998
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1BI2
 | | STRUCTURE OF APO-AND HOLO-DIPHTHERIA TOXIN REPRESSOR | | Descriptor: | DIPHTHERIA TOXIN REPRESSOR | | Authors: | Pohl, E, Hol, W.G.J. | | Deposit date: | 1998-06-21 | | Release date: | 1999-06-22 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Motion of the DNA-binding domain with respect to the core of the diphtheria toxin repressor (DtxR) revealed in the crystal structures of apo- and holo-DtxR.
J.Biol.Chem., 273, 1998
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1C0W
 | | CRYSTAL STRUCTURE OF THE COBALT-ACTIVATED DIPHTHERIA TOXIN REPRESSOR-DNA COMPLEX REVEALS A METAL BINDING SH-LIKE DOMAIN | | Descriptor: | COBALT (II) ION, DIPHTHERIA TOXIN REPRESSOR, DNA (5'-D(P*AP*TP*TP*AP*GP*GP*TP*TP*AP*GP*CP*CP*TP*AP*CP*CP*CP*TP*AP*AP*T)-3'), ... | | Authors: | Pohl, E, Holmes, R.K, Hol, W.G. | | Deposit date: | 1999-07-22 | | Release date: | 2000-07-22 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Crystal structure of a cobalt-activated diphtheria toxin repressor-DNA complex reveals a metal-binding SH3-like domain.
J.Mol.Biol., 292, 1999
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4BYY
 | | Apo GlxR | | Descriptor: | GLYCEROL, PHOSPHATE ION, TRANSCRIPTIONAL REGULATOR, ... | | Authors: | Pohl, E, Cann, M.J, Townsend, P.D, Money, V.A. | | Deposit date: | 2013-07-21 | | Release date: | 2014-07-30 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.48 Å) | | Cite: | The Crystal Structures of Apo and Camp-Bound Glxr from Corynebacterium Glutamicum Reveal Structural and Dynamic Changes Upon Camp Binding in Crp/Fnr Family Transcription Factors.
Plos One, 9, 2014
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4CMY
 | | Chlorobium tepidum Ferritin | | Descriptor: | FE (III) ION, FERRITIN | | Authors: | Pohl, E, Arenas, M, Townsend, P.D, Yevenes, A. | | Deposit date: | 2014-01-18 | | Release date: | 2014-11-26 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.59 Å) | | Cite: | The Crystal Structure of Ferritin from Chlorobium Tepidum Reveals a New Conformation of the 4-Fold Channel for This Protein Family.
Biochimie, 106, 2014
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7Z3M
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6IA5
 | | Crystal Structure Analysis of Bacillus subtilis 168 XepA | | Descriptor: | ACETATE ION, GLYCEROL, Phage-like element PBSX protein XepA | | Authors: | Freitag-Pohl, S, Pohl, E. | | Deposit date: | 2018-11-26 | | Release date: | 2019-11-20 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.88 Å) | | Cite: | Crystal structures of the Bacillus subtilis prophage lytic cassette proteins XepA and YomS.
Acta Crystallogr D Struct Biol, 75, 2019
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8B9W
 | | Cysteine Synthase from Trypanosoma theileri with PLP bound | | Descriptor: | CHLORIDE ION, GLYCEROL, PYRIDOXAL-5'-PHOSPHATE, ... | | Authors: | Sowerby, K.V, Pohl, E. | | Deposit date: | 2022-10-10 | | Release date: | 2023-05-31 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.75 Å) | | Cite: | Cysteine synthase: multiple structures of a key enzyme in cysteine synthesis and a potential drug target for Chagas disease and leishmaniasis.
Acta Crystallogr D Struct Biol, 79, 2023
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8B9Y
 | | Cysteine Synthase from Trypanosoma cruzi with PLP and OAS | | Descriptor: | Cysteine synthase, putative, GLYCEROL, ... | | Authors: | Sowerby, K.V, Pohl, E. | | Deposit date: | 2022-10-10 | | Release date: | 2023-05-31 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Cysteine synthase: multiple structures of a key enzyme in cysteine synthesis and a potential drug target for Chagas disease and leishmaniasis.
Acta Crystallogr D Struct Biol, 79, 2023
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8B9M
 | | Cysteine Synthase from Leishmania Infantum | | Descriptor: | CHLORIDE ION, Cysteine synthase, GLYCEROL | | Authors: | Sowerby, K.V, Pohl, E. | | Deposit date: | 2022-10-06 | | Release date: | 2023-05-31 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Cysteine synthase: multiple structures of a key enzyme in cysteine synthesis and a potential drug target for Chagas disease and leishmaniasis.
Acta Crystallogr D Struct Biol, 79, 2023
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2YCE
 | | Structure of an Archaeal fructose-1,6-bisphosphate aldolase with the catalytic Lys covalently bound to the carbinolamine intermediate of the substrate. | | Descriptor: | D-MANNITOL-1,6-DIPHOSPHATE, FRUCTOSE-BISPHOSPHATE ALDOLASE CLASS 1 | | Authors: | Lorentzen, E, Siebers, B, Hensel, R, Pohl, E. | | Deposit date: | 2011-03-14 | | Release date: | 2011-04-27 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.93 Å) | | Cite: | Mechanism of the Schiff Base Forming Fructose-1,6-Bisphosphate Aldolase: Structural Analysis of Reaction Intermediates.
Biochemistry, 44, 2005
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7B3N
 | | AmiP amidase-3 from Thermus parvatiensis | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, Cell wall hydrolase, ... | | Authors: | Freitag-Pohl, S, Pohl, E. | | Deposit date: | 2020-12-01 | | Release date: | 2022-06-22 | | Last modified: | 2023-05-10 | | Method: | X-RAY DIFFRACTION (1.793 Å) | | Cite: | AmiP from hyperthermophilic Thermus parvatiensis prophage is a thermoactive and ultrathermostable peptidoglycan lytic amidase.
Protein Sci., 32, 2023
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7PJO
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5FMN
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3MBU
 | | Structure of a bipyridine-modified PNA duplex | | Descriptor: | 1,2-ETHANEDIOL, Bipyridine-PNA, CARBONATE ION, ... | | Authors: | Yeh, J.I, Pohl, E, Truan, D, He, W, Sheldrick, G.M, Du, S, Achim, C. | | Deposit date: | 2010-03-26 | | Release date: | 2011-03-30 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.05 Å) | | Cite: | The crystal structure of non-modified and bipyridine-modified PNA duplexes.
Chemistry, 16, 2010
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3MBS
 | | Crystal structure of 8mer PNA | | Descriptor: | 1,2-ETHANEDIOL, Peptide Nucleic Acid | | Authors: | Yeh, J.I, Pohl, E, Truan, D, He, W, Sheldrick, G.M, Achim, C. | | Deposit date: | 2010-03-26 | | Release date: | 2011-03-30 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.27 Å) | | Cite: | The crystal structure of non-modified and bipyridine-modified PNA duplexes.
Chemistry, 16, 2010
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6HKR
 | | Human Cellular Retinoic Acid Binding Protein II (CRABPII) with bound synthetic retinoid DC271. | | Descriptor: | 1,2-ETHANEDIOL, 4-[2-(4,4-dimethyl-1-propan-2-yl-2,3-dihydroquinolin-6-yl)ethynyl]benzoic acid, Cellular retinoic acid-binding protein 2, ... | | Authors: | Tomlinson, C, Chisholm, D, Whiting, A, Pohl, E. | | Deposit date: | 2018-09-07 | | Release date: | 2018-11-28 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Novel Fluorescence Competition Assay for Retinoic Acid Binding Proteins.
ACS Med Chem Lett, 9, 2018
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4WGF
 | | YcaC from Pseudomonas aeruginosa with hexane-2,5-diol and covalent acrylamide | | Descriptor: | (2R,5R)-hexane-2,5-diol, CHLORIDE ION, PROPIONAMIDE, ... | | Authors: | Groftehauge, M.K, Truan, D, Vasil, A, Denny, P.W, Vasil, M.L, Pohl, E. | | Deposit date: | 2014-09-18 | | Release date: | 2015-07-29 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.34020686 Å) | | Cite: | Crystal Structure of a Hidden Protein, YcaC, a Putative Cysteine Hydrolase from Pseudomonas aeruginosa, with and without an Acrylamide Adduct.
Int J Mol Sci, 16, 2015
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4WH0
 | | YcaC from Pseudomonas aeruginosa with S-mercaptocysteine active site cysteine | | Descriptor: | CHLORIDE ION, Putative hydrolase | | Authors: | Groftehauge, M.K, Truan, D, Vasil, A, Denny, P.W, Vasil, M.L, Pohl, E. | | Deposit date: | 2014-09-19 | | Release date: | 2015-07-29 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.563 Å) | | Cite: | Crystal Structure of a Hidden Protein, YcaC, a Putative Cysteine Hydrolase from Pseudomonas aeruginosa, with and without an Acrylamide Adduct.
Int J Mol Sci, 16, 2015
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