1JPG
 
 | | Crystal Structure Of The LCMV Peptidic Epitope Np396 In Complex With The Murine Class I Mhc Molecule H-2Db | | 分子名称: | BETA-2-MICROGLOBULIN, H-2 CLASS I HISTOCOMPATIBILITY ANTIGEN, D-B ALPHA CHAIN, ... | | 著者 | Ciatto, C, Tissot, A.C, Tschopp, M, Capitani, G, Pecorari, F, Pluckthun, A, Grutter, M.G. | | 登録日 | 2001-08-02 | | 公開日 | 2001-10-24 | | 最終更新日 | 2022-12-21 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Zooming in on the hydrophobic ridge of H-2D(b): implications for the conformational variability of bound peptides.
J.Mol.Biol., 312, 2001
|
|
6S9O
 | | Designed Armadillo Repeat protein internal Lock1 fused to target peptide KRKRKLKFKR | | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, designed Armadillo repeat protein with internal Lock1 fused to target peptide KRKRKLKFKR | | 著者 | Ernst, P, Zosel, F, Reichen, C, Schuler, B, Pluckthun, A. | | 登録日 | 2019-07-15 | | 公開日 | 2020-02-19 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (3.17 Å) | | 主引用文献 | Structure-Guided Design of a Peptide Lock for Modular Peptide Binders.
Acs Chem.Biol., 15, 2020
|
|
6S9M
 | | Designed Armadillo Repeat protein Lock2 fused to target peptide KRKRKAKITW | | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, Lock2_KRKRKAKITW, ... | | 著者 | Ernst, P, Zosel, F, Reichen, C, Schuler, B, Pluckthun, A. | | 登録日 | 2019-07-15 | | 公開日 | 2020-02-19 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure-Guided Design of a Peptide Lock for Modular Peptide Binders.
Acs Chem.Biol., 15, 2020
|
|
6S9P
 | | Designed Armadillo Repeat protein internal Lock2 fused to target peptide KRKAKITWKR | | 分子名称: | 1,2-ETHANEDIOL, internal Lock2 fused to target peptide KRKAKITWKR | | 著者 | Ernst, P, Zosel, F, Reichen, C, Schuler, B, Pluckthun, A. | | 登録日 | 2019-07-15 | | 公開日 | 2020-02-19 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structure-Guided Design of a Peptide Lock for Modular Peptide Binders.
Acs Chem.Biol., 15, 2020
|
|
6SA6
 | | DARPin-Armadillo fusion A5 | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, DARPin-Armadillo fusion A5 | | 著者 | Ernst, P, Honegger, A, van der Valk, F, Ewald, C, Mittl, P.R.E, Pluckthun, A. | | 登録日 | 2019-07-16 | | 公開日 | 2019-11-20 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Rigid fusions of designed helical repeat binding proteins efficiently protect a binding surface from crystal contacts.
Sci Rep, 9, 2019
|
|
6FJ3
 | | High resolution crystal structure of parathyroid hormone 1 receptor in complex with a peptide agonist. | | 分子名称: | ACETIC ACID, CHLORIDE ION, OLEIC ACID, ... | | 著者 | Ehrenmann, J, Schoppe, J, Klenk, C, Rappas, M, Kummer, L, Dore, A.S, Pluckthun, A. | | 登録日 | 2018-01-19 | | 公開日 | 2018-11-21 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | High-resolution crystal structure of parathyroid hormone 1 receptor in complex with a peptide agonist.
Nat. Struct. Mol. Biol., 25, 2018
|
|
6FP8
 | | mTFP1/DARPin 1238_E11 complex in space group C2 | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, DARPin1238_E11, ... | | 著者 | Jakob, R.P, Vigano, M.A, Bieli, D, Matsuda, S, Schaefer, J.V, Pluckthun, A, Affolter, M, Maier, T. | | 登録日 | 2018-02-09 | | 公開日 | 2018-10-03 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.855 Å) | | 主引用文献 | DARPins recognizing mTFP1 as novel reagents forin vitroandin vivoprotein manipulations.
Biol Open, 7, 2018
|
|
4D4E
 | | Crystal structure of computationally designed armadillo repeat proteins for modular peptide recognition. | | 分子名称: | ARMADILLO REPEAT PROTEIN ARM00016, GLYCEROL | | 著者 | Reichen, C, Forzani, C, Zhou, T, Parmeggiani, F, Fleishman, S.J, Mittl, P.R.E, Madhurantakam, C, Honegger, A, Ewald, C, Zerbe, O, Baker, D, Caflisch, A, Pluckthun, A. | | 登録日 | 2014-10-28 | | 公開日 | 2016-01-13 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Computationally Designed Armadillo Repeat Proteins for Modular Peptide Recognition.
J.Mol.Biol., 428, 2016
|
|
6S9N
 | | Designed Armadillo Repeat protein Lock2 fused to target peptide KRKRKAKLSF | | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, Lock2_KRKRKAKLSF | | 著者 | Ernst, P, Zosel, F, Reichen, C, Schuler, B, Pluckthun, A. | | 登録日 | 2019-07-15 | | 公開日 | 2020-02-19 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structure-Guided Design of a Peptide Lock for Modular Peptide Binders.
Acs Chem.Biol., 15, 2020
|
|
6S9L
 | | Designed Armadillo Repeat protein Lock1 bound to (KR)4KLSF target | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, KR4KLSF Lock1, LYS-ARG-LYS-ARG-LYS-ARG-LYS-ARG-LYS-LEU-SER-PHE | | 著者 | Ernst, P, Zosel, F, Reichen, C, Schuler, B, Pluckthun, A. | | 登録日 | 2019-07-15 | | 公開日 | 2020-02-19 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structure-Guided Design of a Peptide Lock for Modular Peptide Binders.
Acs Chem.Biol., 15, 2020
|
|
4D49
 | | Crystal structure of computationally designed armadillo repeat proteins for modular peptide recognition. | | 分子名称: | ARGININE, ARMADILLO REPEAT PROTEIN ARM00027, POLY ARG DECAPEPTIDE | | 著者 | Reichen, C, Forzani, C, Zhou, T, Parmeggiani, F, Fleishman, S.J, Mittl, P.R.E, Madhurantakam, C, Honegger, A, Ewald, C, Zerbe, O, Baker, D, Caflisch, A, Pluckthun, A. | | 登録日 | 2014-10-27 | | 公開日 | 2016-01-13 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | Computationally Designed Armadillo Repeat Proteins for Modular Peptide Recognition.
J.Mol.Biol., 428, 2016
|
|
6FP7
 | | mTFP1/DARPin 1238_E11 complex in space group P6522 | | 分子名称: | DARPin1238_E11, GFP-like fluorescent chromoprotein cFP484, GLYCEROL | | 著者 | Jakob, R.P, Vigano, M.A, Bieli, D, Matsuda, S, Schaefer, J.V, Pluckthun, A, Affolter, M, Maier, T. | | 登録日 | 2018-02-09 | | 公開日 | 2018-10-03 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.576 Å) | | 主引用文献 | DARPins recognizing mTFP1 as novel reagents forin vitroandin vivoprotein manipulations.
Biol Open, 7, 2018
|
|
6FPA
 | | Crystal structure of anti-mTFP1 DARPin 1238_G01 in space group P212121 | | 分子名称: | DARPin 1238_G01 | | 著者 | Jakob, R.P, Vigano, M.A, Bieli, D, Matsuda, S, Schaefer, J.V, Pluckthun, A, Affolter, M, Maier, T. | | 登録日 | 2018-02-09 | | 公開日 | 2018-10-03 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | | 主引用文献 | DARPins recognizing mTFP1 as novel reagents forin vitroandin vivoprotein manipulations.
Biol Open, 7, 2018
|
|
6FP9
 | | Crystal structure of anti-mTFP1 DARPin 1238_E11 | | 分子名称: | 1,2-ETHANEDIOL, DARPin 1238_E11, SULFATE ION | | 著者 | Jakob, R.P, Vigano, M.A, Bieli, D, Matsuda, S, Schaefer, J.V, Pluckthun, A, Affolter, M, Maier, T. | | 登録日 | 2018-02-09 | | 公開日 | 2018-10-03 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | DARPins recognizing mTFP1 as novel reagents forin vitroandin vivoprotein manipulations.
Biol Open, 7, 2018
|
|
6FPB
 | | Crystal structure of anti-mTFP1 DARPin 1238_G01 in space group I4 | | 分子名称: | CHLORIDE ION, DARPin 1238_G01 | | 著者 | Jakob, R.P, Vigano, M.A, Bieli, D, Matsuda, S, Schaefer, J.V, Pluckthun, A, Affolter, M, Maier, T. | | 登録日 | 2018-02-09 | | 公開日 | 2018-10-03 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.617 Å) | | 主引用文献 | DARPins recognizing mTFP1 as novel reagents forin vitroandin vivoprotein manipulations.
Biol Open, 7, 2018
|
|
6SH9
 | | EngBF DARPin Fusion 4b D12 | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Endo-alpha-N-acetylgalactosaminidase,DARPin 4b D12, ... | | 著者 | Ernst, P, Pluckthun, A, Mittl, P.R.E. | | 登録日 | 2019-08-06 | | 公開日 | 2019-11-06 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural analysis of biological targets by host:guest crystal lattice engineering.
Sci Rep, 9, 2019
|
|
6S9T
 | | Dimerization domain of Xenopus laevis LDB1 in complex with darpin 3 | | 分子名称: | Darpin 3, LIM domain-binding protein 1, TETRAETHYLENE GLYCOL | | 著者 | Renko, M, Schaefer, J.V, Pluckthun, A, Bienz, M. | | 登録日 | 2019-07-15 | | 公開日 | 2019-10-09 | | 最終更新日 | 2019-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Rotational symmetry of the structured Chip/LDB-SSDP core module of the Wnt enhanceosome.
Proc.Natl.Acad.Sci.USA, 116, 2019
|
|
6S9S
 | | Dimerization domain of Xenopus laevis LDB1 in complex with darpin 10 | | 分子名称: | Darpin 10, LIM domain-binding protein 1 | | 著者 | Renko, M, Schaefer, J.V, Pluckthun, A, Bienz, M. | | 登録日 | 2019-07-15 | | 公開日 | 2019-10-09 | | 最終更新日 | 2019-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Rotational symmetry of the structured Chip/LDB-SSDP core module of the Wnt enhanceosome.
Proc.Natl.Acad.Sci.USA, 116, 2019
|
|
4DBA
 | | Designed Armadillo repeat protein (YIIM3AII) | | 分子名称: | Designed Armadillo repeat protein, YIIM3AII, GLYCEROL | | 著者 | Madhurantakam, C, Varadamsetty, G, Grutter, M.G, Pluckthun, A, Mittl, P.R.E. | | 登録日 | 2012-01-13 | | 公開日 | 2012-05-16 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structure-based optimization of designed Armadillo-repeat proteins.
Protein Sci., 21, 2012
|
|
4DUI
 | | DARPIN D1 binding to tubulin beta chain (not in complex) | | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, DESIGNED ANKYRIN REPEAT PROTEIN (DARPIN) D1 | | 著者 | Pecqueur, L, Duellberg, C, Dreier, B, Wang, Q, Jiang, C, Pluckthun, A, Surrey, T, Gigant, B, Knossow, M. | | 登録日 | 2012-02-22 | | 公開日 | 2013-02-27 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.16 Å) | | 主引用文献 | An Anti-Tubulin Darpin Caps the Microtubule Plus-End
To be Published
|
|
6GCU
 | | MET receptor in complex with InlB internalin domain and DARPin A3A | | 分子名称: | DARPin A3A, Hepatocyte growth factor receptor, Internalin B | | 著者 | Meyer, T, Andres, F, Iamele, L, Gherardi, E, Pluckthun, A, Niemann, H.H. | | 登録日 | 2018-04-19 | | 公開日 | 2019-05-15 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (6.001 Å) | | 主引用文献 | Inhibition of the MET Kinase Activity and Cell Growth in MET-Addicted Cancer Cells by Bi-Paratopic Linking.
J.Mol.Biol., 431, 2019
|
|
4DB8
 | | Designed Armadillo-repeat Protein | | 分子名称: | Armadillo-repeat Protein, MAGNESIUM ION | | 著者 | Madhurantakam, C, Varadamsetty, G, Grutter, M.G, Pluckthun, A, Mittl, P.R.E. | | 登録日 | 2012-01-13 | | 公開日 | 2012-05-16 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structure-based optimization of designed Armadillo-repeat proteins.
Protein Sci., 21, 2012
|
|
4DB9
 | | Designed Armadillo repeat protein (YIIIM3AIII) | | 分子名称: | Armadillo repeat protein, YIIIM3AIII | | 著者 | Madhurantakam, C, Varadamsetty, G, Grutter, M.G, Pluckthun, A, Mittl, P.R.E. | | 登録日 | 2012-01-13 | | 公開日 | 2012-05-16 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structure-based optimization of designed Armadillo-repeat proteins.
Protein Sci., 21, 2012
|
|
4DB6
 | | Designed Armadillo repeat protein (YIIIM3AII) | | 分子名称: | Armadillo repeat protein | | 著者 | Madhurantakam, C, Varadamsetty, G, Grutter, M.G, Pluckthun, A, Mittl, P.R.E. | | 登録日 | 2012-01-13 | | 公開日 | 2012-05-16 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structure-based optimization of designed Armadillo-repeat proteins.
Protein Sci., 21, 2012
|
|
1P4B
 | | Three-Dimensional Structure Of a Single Chain Fv Fragment Complexed With The peptide GCN4(7P-14P). | | 分子名称: | Antibody Variable heavy chain, Antibody Variable light chain, GCN4(7P-14P) peptide | | 著者 | Zahnd, C, Spinelli, S, Luginbuhl, B, Jermutus, L, Amstutz, P, Cambillau, C, Pluckthun, A. | | 登録日 | 2003-04-22 | | 公開日 | 2004-05-04 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Directed in Vitro Evolution and Crystallographic Analysis of a Peptide-binding Single Chain Antibody Fragment (scFv) with Low Picomolar Affinity.
J.Biol.Chem., 279, 2004
|
|
