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PDB: 46 件
4JXX
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Crystal structure of E coli E. coli glutaminyl-tRNA synthetase bound to tRNA(Gln)(CUG) and ATP from novel cryostabilization conditions
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Glutamine--tRNA ligase, RNA (71-MER), ...
著者Perona, J.J, Rodriguez-Hernandez, A.
登録日2013-03-28
公開日2013-05-01
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural and Mechanistic Basis for Enhanced Translational Efficiency by 2-Thiouridine at the tRNA Anticodon Wobble Position.
J.Mol.Biol., 425, 2013
4JYZ
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Crystal structure of E. coli glutaminyl-tRNA synthetase bound to ATP and native tRNA(Gln) containing the cmnm5s2U34 anticodon wobble base
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Glutamine--tRNA ligase, RNA (72-MER), ...
著者Perona, J.J, Rodriguez-Hernandez, A.
登録日2013-04-01
公開日2013-05-29
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural and Mechanistic Basis for Enhanced Translational Efficiency by 2-Thiouridine at the tRNA Anticodon Wobble Position.
J.Mol.Biol., 425, 2013
4JXZ
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BU of 4jxz by Molmil
Structure of E. coli glutaminyl-tRNA synthetase bound to ATP and a tRNA(Gln) acceptor containing a UUG anticodon
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Glutamine--tRNA ligase, RNA (71-MER), ...
著者Perona, J.J, Rodriguez-Hernandez, A.
登録日2013-03-28
公開日2013-05-01
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural and Mechanistic Basis for Enhanced Translational Efficiency by 2-Thiouridine at the tRNA Anticodon Wobble Position.
J.Mol.Biol., 425, 2013
1BGB
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BU of 1bgb by Molmil
ECORV ENDONUCLEASE COMPLEX WITH 5'-CGGGATATCCC DNA
分子名称: DNA (5'-D(*CP*GP*GP*GP*AP*TP*AP*TP*CP*CP*C)-3'), ECORV ENDONUCLEASE
著者Perona, J, Horton, N.C.
登録日1998-05-28
公開日1998-10-28
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Recognition of flanking DNA sequences by EcoRV endonuclease involves alternative patterns of water-mediated contacts.
J.Biol.Chem., 273, 1998
1BRC
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BU of 1brc by Molmil
RELOCATING A NEGATIVE CHARGE IN THE BINDING POCKET OF TRYPSIN
分子名称: AMYLOID BETA-PROTEIN PRECURSOR INHIBITOR DOMAIN (APPI), TRYPSIN
著者Perona, J.J, Fletterick, R.J.
登録日1992-12-17
公開日1994-05-31
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Relocating a negative charge in the binding pocket of trypsin.
J.Mol.Biol., 230, 1993
1BSS
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BU of 1bss by Molmil
ECORV-T93A/DNA/CA2+
分子名称: 5'-D(*AP*AP*AP*GP*AP*TP*AP*TP*CP*TP*T)-3', CALCIUM ION, ECORV ENDONUCLEASE
著者Perona, J.J, Horton, N.C.
登録日1998-08-30
公開日1998-09-02
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Metal ion-mediated substrate-assisted catalysis in type II restriction endonucleases
Proc.Natl.Acad.Sci.USA, 95, 1998
1BUA
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BU of 1bua by Molmil
STRUCTURAL AND ENERGETIC ORIGINS OF INDIRECT READOUT IN SITE-SPECIFIC DNA CLEAVAGE BY A RESTRICTION ENDONUCLEASE
分子名称: DNA (5'-D(*AP*AP*AP*GP*AP*CP*IP*TP*CP*TP*T)-3'), ENDONUCLEASE ECORV
著者Perona, J.J, Martin, A.M.
登録日1998-09-03
公開日1998-09-09
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structural and energetic origins of indirect readout in site-specific DNA cleavage by a restriction endonuclease.
Nat.Struct.Biol., 6, 1999
1BSU
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STRUCTURAL AND ENERGETIC ORIGINS OF INDIRECT READOUT IN SITE-SPECIFIC DNA CLEAVAGE BY A RESTRICTION ENDONUCLEASE
分子名称: CALCIUM ION, DNA (5'-D(*AP*AP*AP*GP*AP*(5CM)P*IP*TP*CP*TP*T)-3'), DNA (5'-D(P*AP*AP*GP*AP*(5CM)P*IP*TP*CP*TP*T)-3'), ...
著者Perona, J.J, Martin, A.M.
登録日1998-08-30
公開日1998-09-09
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural and energetic origins of indirect readout in site-specific DNA cleavage by a restriction endonuclease.
Nat.Struct.Biol., 6, 1999
1BRB
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CRYSTAL STRUCTURES OF RAT ANIONIC TRYPSIN COMPLEXED WITH THE PROTEIN INHIBITORS APPI AND BPTI
分子名称: PANCREATIC TRYPSIN INHIBITOR, TRYPSIN
著者Perona, J.J, Fletterick, R.J.
登録日1992-12-17
公開日1994-07-31
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structures of rat anionic trypsin complexed with the protein inhibitors APPI and BPTI.
J.Mol.Biol., 230, 1993
1BRA
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BU of 1bra by Molmil
RELOCATING A NEGATIVE CHARGE IN THE BINDING POCKET OF TRYPSIN
分子名称: BENZAMIDINE, CALCIUM ION, TRYPSIN
著者Perona, J.J, Mcgrath, M.E, Fletterick, R.J.
登録日1992-12-17
公開日1994-04-30
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Relocating a negative charge in the binding pocket of trypsin.
J.Mol.Biol., 230, 1993
1GTS
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BU of 1gts by Molmil
STRUCTURAL BASIS FOR TRANSFER RNA AMINOACEYLATION BY ESCHERICHIA COLI GLUTAMINYL-TRNA SYNTHETASE
分子名称: ADENOSINE MONOPHOSPHATE, PROTEIN (GLUTAMINYL-TRNA SYNTHETASE (E.C.6.1.1.18)), TRNAGLN
著者Perona, J.J, Steitz, T.A, Rould, M.A.
登録日1993-09-15
公開日1995-02-07
最終更新日2017-02-15
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis for transfer RNA aminoacylation by Escherichia coli glutaminyl-tRNA synthetase.
Biochemistry, 32, 1993
1AZ3
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BU of 1az3 by Molmil
ECORV ENDONUCLEASE, UNLIGANDED, FORM B
分子名称: ECORV ENDONUCLEASE
著者Perona, J, Martin, A.
登録日1997-11-24
公開日1998-05-27
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Conformational transitions and structural deformability of EcoRV endonuclease revealed by crystallographic analysis.
J.Mol.Biol., 273, 1997
1AZ4
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ECORV ENDONUCLEASE, UNLIGANDED, FORM B, T93A MUTANT
分子名称: ECORV ENDONUCLEASE
著者Perona, J, Martin, A.
登録日1997-11-24
公開日1998-05-27
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Conformational transitions and structural deformability of EcoRV endonuclease revealed by crystallographic analysis.
J.Mol.Biol., 273, 1997
1AZ0
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BU of 1az0 by Molmil
ECORV ENDONUCLEASE/DNA COMPLEX
分子名称: CALCIUM ION, DNA (5'-D(*AP*AP*AP*GP*AP*TP*AP*TP*CP*TP*T)-3'), PROTEIN (TYPE II RESTRICTION ENZYME ECORV)
著者Perona, J.J, Martin, A.M.
登録日1997-11-24
公開日1998-06-19
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Conformational transitions and structural deformability of EcoRV endonuclease revealed by crystallographic analysis.
J.Mol.Biol., 273, 1997
1AZZ
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BU of 1azz by Molmil
FIDDLER CRAB COLLAGENASE COMPLEXED TO ECOTIN
分子名称: COLLAGENASE, ECOTIN
著者Perona, J.J, Fletterick, R.J.
登録日1997-11-24
公開日1998-02-25
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of an ecotin-collagenase complex suggests a model for recognition and cleavage of the collagen triple helix.
Biochemistry, 36, 1997
2GE5
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BU of 2ge5 by Molmil
EcoRV Restriction Endonuclease C-terminal deletion mutant/GATATC/Ca2+
分子名称: 5'-D(*AP*AP*AP*GP*AP*TP*AP*TP*CP*TP*T)-3', CALCIUM ION, Type II restriction enzyme EcoRV
著者Hiller, D.A, Perona, J.J.
登録日2006-03-17
公開日2006-07-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Positively Charged C-Terminal Subdomains of EcoRV Endonuclease: Contributions to DNA Binding, Bending, and Cleavage.
Biochemistry, 45, 2006
2B0E
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BU of 2b0e by Molmil
EcoRV Restriction Endonuclease/GAAUTC/Ca2+
分子名称: 5'-D(*AP*AP*AP*GP*AP*AP*(DU)P*TP*CP*TP*T)-3', CALCIUM ION, Type II restriction enzyme EcoRV
著者Hiller, D.A, Rodriguez, A.M, Perona, J.J.
登録日2005-09-13
公開日2005-09-27
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Non-cognate Enzyme-DNA Complex: Structural and Kinetic Analysis of EcoRV Endonuclease Bound to the EcoRI Recognition Site GAATTC
J.Mol.Biol., 354, 2005
2B0D
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BU of 2b0d by Molmil
EcoRV Restriction Endonuclease/GAATTC/Ca2+
分子名称: 5'-D(*AP*AP*AP*GP*AP*AP*TP*TP*CP*TP*T)-3', CALCIUM ION, Type II restriction enzyme EcoRV
著者Hiller, D.A, Rodriguez, A.M, Perona, J.J.
登録日2005-09-13
公開日2005-09-27
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Non-cognate Enzyme-DNA Complex: Structural and Kinetic Analysis of EcoRV Endonuclease Bound to the EcoRI Recognition Site GAATTC
J.Mol.Biol., 354, 2005
2RE8
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BU of 2re8 by Molmil
Glutaminyl-tRNA synthetase mutant C229R with bound analog 5'-O-[N-(L-GLUTAMYL)-SULFAMOYL]ADENOSINE
分子名称: Glutamine tRNA, Glutaminyl-tRNA synthetase, O5'-(L-GLUTAMYL-SULFAMOYL)-ADENOSINE, ...
著者Bullock, T.L, Perona, J.J.
登録日2007-09-25
公開日2008-01-15
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献A rationally engineered misacylating aminoacyl-tRNA synthetase.
Proc.Natl.Acad.Sci.Usa, 105, 2008
2RD2
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BU of 2rd2 by Molmil
Glutaminyl-tRNA synthetase mutant C229R with bound analog 5'-O-[N-(L-GLUTAMINYL)-SULFAMOYL]ADENOSINE
分子名称: 5'-O-[N-(L-GLUTAMINYL)-SULFAMOYL]ADENOSINE, Glutamine tRNA, Glutaminyl-tRNA synthetase, ...
著者Bullock, T.L, Perona, J.J.
登録日2007-09-20
公開日2008-01-15
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献A rationally engineered misacylating aminoacyl-tRNA synthetase.
Proc.Natl.Acad.Sci.Usa, 105, 2008
1LI5
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BU of 1li5 by Molmil
Crystal Structure of Cysteinyl-tRNA Synthetase
分子名称: CYSTEINYL-TRNA SYNTHETASE, ZINC ION
著者Newberry, K.J, Hou, Y.-M, Perona, J.J.
登録日2002-04-17
公開日2002-04-26
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural origins of amino acid selection without editing by cysteinyl-tRNA synthetase
EMBO J., 21, 2002
1LI7
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BU of 1li7 by Molmil
Crystal Structure of Cysteinyl-tRNA Synthetase with Cysteine Substrate Bound
分子名称: CYSTEINE, CYSTEINYL-TRNA SYNTHETASE, ZINC ION
著者Newberry, K.J, Hou, Y.-M, Perona, J.J.
登録日2002-04-17
公開日2002-04-26
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural origins of amino acid selection without editing by cysteinyl-tRNA synthetase
EMBO J., 21, 2002
1ZJW
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BU of 1zjw by Molmil
Glutaminyl-tRNA synthetase complexed to glutamine and 2'deoxy A76 glutamine tRNA
分子名称: ADENOSINE MONOPHOSPHATE, GLUTAMINE, Glutaminyl-tRNA, ...
著者Gruic-Sovulj, I, Uter, N, Bullock, T, Perona, J.J.
登録日2005-05-01
公開日2005-06-07
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献tRNA-dependent Aminoacyl-adenylate Hydrolysis by a Nonediting Class I Aminoacyl-tRNA Synthetase.
J.Biol.Chem., 280, 2005
1KC6
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BU of 1kc6 by Molmil
HincII Bound to Cognate DNA
分子名称: 5'-D(P*CP*CP*GP*GP*TP*CP*GP*AP*CP*CP*GP*G)-3', SODIUM ION, TYPE II RESTRICTION ENZYME HINCII
著者Horton, N.C, Dorner, L.F, Perona, J.J.
登録日2001-11-07
公開日2001-12-07
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Sequence selectivity and degeneracy of a restriction endonuclease mediated by DNA intercalation.
Nat.Struct.Biol., 9, 2002
1NYL
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BU of 1nyl by Molmil
Unliganded glutaminyl-tRNA synthetase
分子名称: Glutaminyl-tRNA synthetase
著者Sherlin, L.D, Perona, J.P.
登録日2003-02-12
公開日2003-02-25
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献tRNA-Dependent Active Site Assembly in a Class I Aminoacyl-tRNA Synthetase.
Structure, 11, 2003

 

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