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PDB: 143 件

6CJC
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CRYSTAL STRUCTURE OF A FC FRAGMENT LALA MUTANT (L234A, L235A) OF HUMAN IGG1 (CRYSTAL FORM 3)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Uncharacterized protein DKFZp686C11235
著者Tolbert, W.D, Van, V, Pazgier, M.
登録日2018-02-26
公開日2019-03-06
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.575 Å)
主引用文献Antigen-Induced Allosteric Changes in a Human IgG1 Fc Increase Low-Affinity Fc gamma Receptor Binding.
Structure, 28, 2020
6CHF
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Crystal structure of a Fc fragment LALA mutant (L234A, L235A) of human IgG1 (crystal form 1)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Uncharacterized protein DKFZp686C11235
著者Gohain, N, Tolbert, W.D, Pazgier, M.
登録日2018-02-22
公開日2019-02-27
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Antigen-Induced Allosteric Changes in a Human IgG1 Fc Increase Low-Affinity Fc gamma Receptor Binding.
Structure, 2020
6D58
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Crystal structure of a Fc fragment of Human IgG3
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoglobulin heavy constant gamma 3
著者Gohain, N, Tolbert, W.D, Pazgier, M.
登録日2018-04-19
公開日2019-05-15
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Crystal structure of a Fc fragment of Human IgG3.
To Be Published
6D4E
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Crystal Structure of a Fc Fragment of Rhesus macaque (Macaca mulatta) IgG1.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Fc Fragment of IgG1
著者Gohain, N, Tolbert, W.D, Pazgier, M.
登録日2018-04-18
公開日2019-05-01
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献From Rhesus macaque to human: structural evolutionary pathways for immunoglobulin G subclasses.
Mabs, 11, 2019
2NLB
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Human beta-defensin-1 (Mutant Asn4Ala)
分子名称: Beta-defensin 1, SULFATE ION
著者Lubkowski, J, Pazgier, M.
登録日2006-10-20
公開日2006-10-31
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Studies of the Biological Properties of Human beta-Defensin 1.
J.Biol.Chem., 282, 2007
2NLP
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Human beta-defensin-1 (Mutant Gln24Glu)
分子名称: Beta-defensin 1, SULFATE ION
著者Lubkowski, J, Pazgier, M.
登録日2006-10-20
公開日2006-10-31
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Studies of the Biological Properties of Human beta-Defensin 1.
J.Biol.Chem., 282, 2007
4DU0
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Crystal structure of human alpha-defensin 1, HNP1 (G17A mutant)
分子名称: CHLORIDE ION, GLYCEROL, Neutrophil defensin 1
著者Wu, X, Lu, W, Pazgier, M.
登録日2012-02-21
公開日2012-04-11
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Invariant gly residue is important for alpha-defensin folding, dimerization, and function: a case study of the human neutrophil alpha-defensin HNP1
J.Biol.Chem., 287, 2012
2NLG
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Human beta-defensin-1 (Mutant Lys22Glu)
分子名称: Beta-defensin 1, SULFATE ION
著者Lubkowski, J, Pazgier, M.
登録日2006-10-20
公開日2006-10-31
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Studies of the Biological Properties of Human beta-Defensin 1.
J.Biol.Chem., 282, 2007
2NLQ
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Human beta-defensin-1 (Mutant Lys31Ala)
分子名称: Beta-defensin 1, GLYCEROL, GLYCINE, ...
著者Lubkowski, J, Pazgier, M.
登録日2006-10-20
公開日2006-10-31
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Studies of the Biological Properties of Human beta-Defensin 1.
J.Biol.Chem., 282, 2007
2NLC
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Human beta-defensin-1 (mutant Ser8Ala)
分子名称: ACETATE ION, Beta-defensin 1, SULFATE ION
著者Lubkowski, J, Pazgier, M.
登録日2006-10-20
公開日2006-10-31
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Studies of the Biological Properties of Human beta-Defensin 1.
J.Biol.Chem., 282, 2007
4FZE
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BU of 4fze by Molmil
Crystal structure of N26_i1 Fab, an ADCC mediating anti-HIV-1 antibody.
分子名称: N26_i1 Fab heavy chain, N26_i1 Fab light chain
著者Tolbert, W.D, Wu, X, Pazgier, M.
登録日2012-07-06
公開日2013-07-10
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.999 Å)
主引用文献Crystal structure of N26_i1 Fab, an ADCC mediating anti-HIV-1 antibody.
To be Published
2NLH
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Human beta-defensin-1 (Mutant GLN24ALA)
分子名称: ACETATE ION, Beta-defensin 1, SULFATE ION
著者Lubkowski, J, Pazgier, M.
登録日2006-10-20
公開日2006-10-31
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Studies of the Biological Properties of Human beta-Defensin 1.
J.Biol.Chem., 282, 2007
6D4M
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Crystal Structure of a Fc Fragment of Rhesus macaque (Macaca mulatta) IgG3
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Fc fragment of IgG3
著者Gohain, N, Tolbert, W.D, Pazgier, M.
登録日2018-04-18
公開日2019-05-01
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.47 Å)
主引用文献From Rhesus macaque to human: structural evolutionary pathways for immunoglobulin G subclasses.
Mabs, 11, 2019
6D4N
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Crystal structure of a Fc fragment of Rhesus macaque (Macaca mulatta) IgG4
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Fc fragment of IgG4
著者Gohain, N, Tolbert, W.D, Pazgier, M.
登録日2018-04-18
公開日2019-05-01
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献From Rhesus macaque to human: structural evolutionary pathways for immunoglobulin G subclasses.
Mabs, 11, 2019
2NLD
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Human beta-defensin-1 (Mutant Gln11Ala)
分子名称: ACETATE ION, Beta-defensin 1, SULFATE ION
著者Lubkowski, J, Pazgier, M.
登録日2006-10-20
公開日2006-10-31
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.49 Å)
主引用文献Studies of the Biological Properties of Human beta-Defensin 1.
J.Biol.Chem., 282, 2007
2NLE
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Human beta-defensin-1 (Mutant Gln11Ala)
分子名称: ACETATE ION, Beta-defensin 1, SULFATE ION
著者Lubkowski, J, Pazgier, M.
登録日2006-10-20
公開日2006-10-31
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Studies of the Biological Properties of Human beta-Defensin 1.
J.Biol.Chem., 282, 2007
2NLS
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Human beta-defensin-1 (Mutant Gln24Ala)
分子名称: Beta-defensin 1
著者Lubkowski, J, Pazgier, M.
登録日2006-10-20
公開日2006-10-31
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (0.98 Å)
主引用文献Studies of the Biological Properties of Human beta-Defensin 1.
J.Biol.Chem., 282, 2007
2NLF
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Human beta-defensin-1 (Mutant Leu13Glu)
分子名称: Beta-defensin 1, SULFATE ION
著者Lubkowski, J, Pazgier, M.
登録日2006-10-20
公開日2006-10-31
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Studies of the Biological Properties of Human beta-Defensin 1.
J.Biol.Chem., 282, 2007

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