8Q63
 
 | | Cryo-EM structure of IC8', a second state of yeast mitochondrial RNA polymerase transcription initiation complex with 8-mer RNA, pppGpGpUpApApApUpG | | 分子名称: | DNA-directed RNA polymerase, mitochondrial, GUANOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Goovaerts, Q, Shen, J, Patel, S.S, Das, K. | | 登録日 | 2023-08-10 | | 公開日 | 2023-08-30 | | 最終更新日 | 2023-11-01 | | 実験手法 | ELECTRON MICROSCOPY (3.68 Å) | | 主引用文献 | Structures illustrate step-by-step mitochondrial transcription initiation.
Nature, 622, 2023
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8AP1
 | | Cryo-EM structure of yeast mitochondrial RNA polymerase transcription initiation complex with two GTP molecules poised for de novo initiation (IC2) | | 分子名称: | DNA-directed RNA polymerase, mitochondrial, GUANOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Goovaerts, Q, Shen, J, Patel, S.S, Das, K. | | 登録日 | 2022-08-09 | | 公開日 | 2023-08-23 | | 最終更新日 | 2023-11-01 | | 実験手法 | ELECTRON MICROSCOPY (3.47 Å) | | 主引用文献 | Structures illustrate step-by-step mitochondrial transcription initiation.
Nature, 622, 2023
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8ATV
 | | Cryo-EM structure of yeast mitochondrial RNA polymerase transcription initiation complex with 5-mer RNA, pppGpGpApApA (IC5) | | 分子名称: | DNA (36-MER), DNA-directed RNA polymerase, mitochondrial, ... | | 著者 | Goovaerts, Q, Shen, J, Patel, S.S, Das, K. | | 登録日 | 2022-08-24 | | 公開日 | 2023-08-30 | | 最終更新日 | 2023-11-01 | | 実験手法 | ELECTRON MICROSCOPY (3.39 Å) | | 主引用文献 | Structures illustrate step-by-step mitochondrial transcription initiation.
Nature, 622, 2023
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8ATW
 | | Cryo-EM structure of yeast mitochondrial RNA polymerase transcription initiation complex with 6-mer RNA, pppGpGpApApApU (IC6) | | 分子名称: | DNA-directed RNA polymerase, mitochondrial, GUANOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Goovaerts, Q, Shen, J, Patel, S.S, Das, K. | | 登録日 | 2022-08-24 | | 公開日 | 2023-08-30 | | 最終更新日 | 2023-11-01 | | 実験手法 | ELECTRON MICROSCOPY (3.62 Å) | | 主引用文献 | Structures illustrate step-by-step mitochondrial transcription initiation.
Nature, 622, 2023
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8ATT
 | | Cryo-EM structure of yeast mitochondrial RNA polymerase transcription initiation complex with 4-mer RNA, pppGpGpUpA (IC4) | | 分子名称: | DNA-directed RNA polymerase, mitochondrial, GUANOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Goovaerts, Q, Shen, J, Patel, S.S, Das, K. | | 登録日 | 2022-08-24 | | 公開日 | 2023-08-30 | | 最終更新日 | 2023-11-01 | | 実験手法 | ELECTRON MICROSCOPY (3.44 Å) | | 主引用文献 | Structures illustrate step-by-step mitochondrial transcription initiation.
Nature, 622, 2023
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4ZTU
 | | Structural basis for processivity and antiviral drug toxicity in human mitochondrial DNA replicase | | 分子名称: | 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, DNA (25-MER), DNA (5'-D(P*AP*AP*GP*AP*CP*GP*AP*GP*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*GP*TP*AP*C)-3'), ... | | 著者 | Szymanski, M.R, Kuznestov, V.B, Shumate, C.K, Meng, Q, Lee, Y.-S, Patel, G, Patel, S.S, Yin, Y.W. | | 登録日 | 2015-05-15 | | 公開日 | 2015-09-23 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (3.299 Å) | | 主引用文献 | Structural basis for processivity and antiviral drug toxicity
in human mitochondrial DNA replicase
EMBO J., 34, 2015
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6YMV
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6YMW
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8C5U
 | | Cryo-EM structure of yeast mitochondrial RNA polymerase transcription initiation complex with 8-mer RNA, pppGpGpUpApApApUpG (IC8) | | 分子名称: | DNA-directed RNA polymerase, mitochondrial, GUANOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Goovaerts, Q, Shen, J, Patel, S.S, Das, K. | | 登録日 | 2023-01-10 | | 公開日 | 2023-08-30 | | 最終更新日 | 2023-11-01 | | 実験手法 | ELECTRON MICROSCOPY (3.62 Å) | | 主引用文献 | Structures illustrate step-by-step mitochondrial transcription initiation.
Nature, 622, 2023
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8C5S
 | | Cryo-EM structure of yeast mitochondrial RNA polymerase transcription initiation complex with 7-mer RNA, pppGpGpUpApApApU (IC7) | | 分子名称: | DNA-directed RNA polymerase, mitochondrial, GUANOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Goovaerts, Q, Shen, J, Patel, S.S, Das, K. | | 登録日 | 2023-01-10 | | 公開日 | 2023-08-30 | | 最終更新日 | 2023-11-01 | | 実験手法 | ELECTRON MICROSCOPY (3.75 Å) | | 主引用文献 | Structures illustrate step-by-step mitochondrial transcription initiation.
Nature, 622, 2023
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