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PDB: 18 件
6PXO
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BU of 6pxo by Molmil
Human Casein Kinase 1 delta (anion-free crystallization conditions)
分子名称: Casein kinase I isoform delta
著者Freeberg, A, Philpott, J.M, Tripathi, S.M, Partch, C.L.
登録日2019-07-26
公開日2020-02-12
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Casein kinase 1 dynamics underlie substrate selectivity and the PER2 circadian phosphoswitch.
Elife, 9, 2020
8GCI
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BU of 8gci by Molmil
Crystal structure of C. elegans LIN-42 PAS-B domain
分子名称: Period protein homolog lin-42
著者Spangler, B.K, Coronado, A.R, Tripathi, S.M, Ward, J.D, Partch, C.L.
登録日2023-03-01
公開日2023-03-15
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.42 Å)
主引用文献Crystal structure of C. elegans LIN-42 PAS-B domain
To Be Published
6X61
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BU of 6x61 by Molmil
Crystal structure of the N-terminal thioredoxin domain of SasA in complex with the N-terminal CI domain of KaiC from Thermosynchococcus elongatus
分子名称: Adaptive-response sensory-kinase SasA, Circadian clock protein kinase KaiC, PHOSPHATE ION
著者Swan, J.A, Tripathi, S.M, Partch, C.L.
登録日2020-05-27
公開日2021-06-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Reconstitution of an intact clock reveals mechanisms of circadian timekeeping.
Science, 374, 2021
5T5X
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BU of 5t5x by Molmil
High resolution structure of mouse Cryptochrome 1
分子名称: CHLORIDE ION, Cryptochrome-1
著者Michael, A.K, Tripathi, S, Partch, C.L.
登録日2016-08-31
公開日2017-02-08
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Formation of a repressive complex in the mammalian circadian clock is mediated by the secondary pocket of CRY1.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6OF7
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BU of 6of7 by Molmil
Crystal structure of the CRY1-PER2 complex
分子名称: Cryptochrome-1, Period circadian protein homolog 2
著者Michael, A.K, Fribourgh, J.L, Tripathi, S.M, Partch, C.L.
登録日2019-03-28
公開日2020-03-04
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.11 Å)
主引用文献Dynamics at the serine loop underlie differential affinity of cryptochromes for CLOCK:BMAL1 to control circadian timing.
Elife, 9, 2020
5JWO
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BU of 5jwo by Molmil
Crystal structure of foldswitch-stabilized KaiB in complex with the N-terminal CI domain of KaiC from Thermosynechococcus elongatus
分子名称: ADENOSINE-5'-DIPHOSPHATE, Circadian clock protein KaiB, Circadian clock protein kinase KaiC
著者Tseng, R, Goularte, N.F, Chavan, A, Luu, J, Chang, Y, Heilser, J, Tripathi, S, LiWang, A, Partch, C.L.
登録日2016-05-12
公開日2017-03-29
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis of the day-night transition in a bacterial circadian clock.
Science, 355, 2017
6PXP
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BU of 6pxp by Molmil
Human Casein Kinase 1 delta Site 2 mutant (K171E)
分子名称: Casein kinase I isoform delta, SULFATE ION
著者Yee, L, Philpott, J.M, Tripathi, S.M, Partch, C.L.
登録日2019-07-26
公開日2020-02-12
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Casein kinase 1 dynamics underlie substrate selectivity and the PER2 circadian phosphoswitch.
Elife, 9, 2020
6PXN
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BU of 6pxn by Molmil
Human Casein Kinase 1 delta Tau mutant (R178C)
分子名称: Casein kinase I isoform delta, SULFATE ION
著者Philpott, J.M, Tripathi, S.M, Partch, C.L.
登録日2019-07-26
公開日2020-02-12
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.551 Å)
主引用文献Casein kinase 1 dynamics underlie substrate selectivity and the PER2 circadian phosphoswitch.
Elife, 9, 2020
8D7M
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BU of 8d7m by Molmil
Human Casein kinase 1 delta in complex with phosphorylated human PERIOD2 FASP peptide
分子名称: Casein kinase I isoform delta, Period circadian protein homolog 2 peptide
著者Philpott, J.M, Freeberg, A.M, Tripathi, S.M, Partch, C.L.
登録日2022-06-07
公開日2023-05-17
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献PERIOD phosphorylation leads to feedback inhibition of CK1 activity to control circadian period.
Mol.Cell, 83, 2023
8D7O
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BU of 8d7o by Molmil
Human Casein kinase 1 delta in complex with phosphorylated human PERIOD2 FASP peptide
分子名称: Casein kinase I isoform delta, Period circadian protein homolog 2 peptide
著者Philpott, J.M, Freeberg, A.M, Tripathi, S.M, Partch, C.L.
登録日2022-06-07
公開日2023-05-17
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献PERIOD phosphorylation leads to feedback inhibition of CK1 activity to control circadian period.
Mol.Cell, 83, 2023
8D7P
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BU of 8d7p by Molmil
Human Casein kinase 1 delta in complex with phosphorylated Drosophila PERIOD peptide
分子名称: Casein kinase I isoform delta, Period circadian protein peptide
著者Philpott, J.M, Freeberg, A.M, Tripathi, S.M, Partch, C.L.
登録日2022-06-07
公開日2023-05-17
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献PERIOD phosphorylation leads to feedback inhibition of CK1 activity to control circadian period.
Mol.Cell, 83, 2023
8D7N
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BU of 8d7n by Molmil
Human Casein kinase 1 delta in complex with phosphorylated human PERIOD2 FASP peptide
分子名称: Casein kinase I isoform delta, Period circadian protein homolog 2 peptide
著者Philpott, J.M, Freeberg, A.M, Tripathi, S.M, Partch, C.L.
登録日2022-06-07
公開日2023-05-17
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献PERIOD phosphorylation leads to feedback inhibition of CK1 activity to control circadian period.
Mol.Cell, 83, 2023
5JWR
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BU of 5jwr by Molmil
Crystal structure of foldswitch-stabilized KaiB in complex with the N-terminal CI domain of KaiC and a dimer of KaiA C-terminal domains from Thermosynechococcus elongatus
分子名称: Circadian clock protein KaiA, Circadian clock protein KaiB, Circadian clock protein kinase KaiC, ...
著者Tseng, R, Goularte, N.F, Chavan, A, Luu, J, Chang, Y.G, Heilser, J, Tripathi, S, LiWang, A, Partch, C.L.
登録日2016-05-12
公開日2017-03-29
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Structural basis of the day-night transition in a bacterial circadian clock.
Science, 355, 2017
5JWQ
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BU of 5jwq by Molmil
Crystal structure of KaiC S431E in complex with foldswitch-stabilized KaiB from Thermosynechococcus elongatus
分子名称: ADENOSINE-5'-DIPHOSPHATE, Circadian clock protein KaiB, Circadian clock protein kinase KaiC
著者Tseng, R, Goularte, N.F, Chavan, A, Luu, J, Chang, Y, Heilser, J, Tripathi, S, LiWang, A, Partch, C.L.
登録日2016-05-12
公開日2017-03-29
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3.871 Å)
主引用文献Structural basis of the day-night transition in a bacterial circadian clock.
Science, 355, 2017
7S65
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BU of 7s65 by Molmil
Compressed conformation of nighttime state KaiC
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Circadian clock protein kinase KaiC, ...
著者Sandate, C.R, Swan, J.A, Partch, C.L, Lander, G.C.
登録日2021-09-13
公開日2021-09-22
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Coupling of distant ATPase domains in the circadian clock protein KaiC.
Nat.Struct.Mol.Biol., 29, 2022
7S67
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BU of 7s67 by Molmil
Extended conformation of daytime state KaiC
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Circadian clock protein kinase KaiC, ...
著者Sandate, C.R, Swan, J.A, Partch, C.L, Lander, G.C.
登録日2021-09-13
公開日2021-09-22
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Coupling of distant ATPase domains in the circadian clock protein KaiC.
Nat.Struct.Mol.Biol., 29, 2022
7S66
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BU of 7s66 by Molmil
Extended conformation of nighttime state KaiC
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Circadian clock protein kinase KaiC, MAGNESIUM ION
著者Sandate, C.R, Swan, J.A, Partch, C.L, Lander, G.C.
登録日2021-09-13
公開日2021-09-22
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Coupling of distant ATPase domains in the circadian clock protein KaiC.
Nat.Struct.Mol.Biol., 29, 2022
4PKY
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BU of 4pky by Molmil
ARNT/HIF transcription factor/coactivator complex
分子名称: Aryl hydrocarbon receptor nuclear translocator, Endothelial PAS domain-containing protein 1, SULFATE ION, ...
著者Tomchick, D.R, Partch, C.L, Gardner, K.H.
登録日2014-05-15
公開日2015-02-11
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Coiled-coil Coactivators Play a Structural Role Mediating Interactions in Hypoxia-inducible Factor Heterodimerization.
J.Biol.Chem., 290, 2015

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件を2024-07-24に公開中

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