7DOO
 
 | | Crystal Structure of PenA beta-Lactamase-Avibactam Complex | | Descriptor: | (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, Beta-lactamase | | Authors: | Nukaga, M, Papp-Wallace, K.M, Bonomo, R.A. | | Deposit date: | 2020-12-15 | | Release date: | 2020-12-23 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Overcoming an Extremely Drug Resistant (XDR) Pathogen: Avibactam Restores Susceptibility to Ceftazidime for Burkholderia cepacia Complex Isolates from Cystic Fibrosis Patients.
Acs Infect Dis., 3, 2017
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5ZA2
 | | Fox-4 beta-lactamase complexed with avibactam | | Descriptor: | (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Beta-lactamase, ... | | Authors: | Nukaga, M, Hoshino, T, Papp-Wallace, K.M, Bonomo, R.A. | | Deposit date: | 2018-02-06 | | Release date: | 2018-03-07 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (1.503 Å) | | Cite: | Probing the Mechanism of Inactivation of the FOX-4 Cephamycinase by Avibactam
Antimicrob. Agents Chemother., 62, 2018
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3W4O
 | | Crystal structure of PenI beta-lactamase from Burkholderia pseudomallei at pH9.5 | | Descriptor: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Beta-lactamase, GLYCEROL | | Authors: | Nukaga, M, Ohuchi, N, Papp-Wallace, K.M, Taracila, M.A, Bonomo, R.A. | | Deposit date: | 2013-01-10 | | Release date: | 2013-05-15 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.18 Å) | | Cite: | Insights into beta-lactamases from Burkholderia species, two phylogenetically related yet distinct resistance determinants
J.Biol.Chem., 288, 2013
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3W4P
 | | Crystal structure of PenI beta-lactamase from Burkholderia pseudomallei at pH7.5 | | Descriptor: | Beta-lactamase, GLYCEROL, SULFATE ION | | Authors: | Nukaga, M, Ohuchi, N, Papp-Wallace, K.M, Taracila, M.A, Bonomo, R.A. | | Deposit date: | 2013-01-10 | | Release date: | 2013-05-15 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.05 Å) | | Cite: | Insights into beta-lactamases from Burkholderia species, two phylogenetically related yet distinct resistance determinants
J.Biol.Chem., 288, 2013
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3W4Q
 | | Crystal structure of PenA beta-lactamase from Burkholderia multivorans at pH4.2 | | Descriptor: | Beta-lactamase | | Authors: | Nukaga, M, Ohuchi, N, Papp-Wallace, K.M, Taracila, M.A, Bonomo, R.A. | | Deposit date: | 2013-01-10 | | Release date: | 2013-05-15 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.2 Å) | | Cite: | Insights into beta-lactamases from Burkholderia species, two phylogenetically related yet distinct resistance determinants
J.Biol.Chem., 288, 2013
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7D5J
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7DDM
 | | Crystal Structure of PenA39 beta-Lactamase | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, ALA-ALA-ARG-ASP-ALA-ALA-VAL-SER-ASP-ALA-ALA-ALA, ... | | Authors: | Nukaga, M, Hoshino, T, Papp-Wallace, K.M. | | Deposit date: | 2020-10-29 | | Release date: | 2021-11-03 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.2 Å) | | Cite: | Frameshift mutations in genes encoding PBP3 and PBP4 trigger an unusual, extreme beta-lactam resistance phenotype in Burkholderia multivorans
To Be Published
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