5K1V
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![BU of 5k1v by Molmil](/molmil-images/mine/5k1v) | Crystal structure of Endoplasmic Reticulum aminopeptidase 2 (ERAP2) in complex with a diaminobenzoic acid derivative ligand. | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Endoplasmic reticulum aminopeptidase 2, ... | 著者 | Saridakis, E, Papakyriakou, A, Giastas, P, Mpakali, A, Mavridis, I.M, Stratikos, E. | 登録日 | 2016-05-18 | 公開日 | 2017-03-29 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.897 Å) | 主引用文献 | Crystal Structures of ERAP2 Complexed with Inhibitors Reveal Pharmacophore Requirements for Optimizing Inhibitor Potency. ACS Med Chem Lett, 8, 2017
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2HU6
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![BU of 2hu6 by Molmil](/molmil-images/mine/2hu6) | Crystal structure of human MMP-12 in complex with acetohydroxamic acid and a bicyclic inhibitor | 分子名称: | (1S,5S,7R)-N~7~-(BIPHENYL-4-YLMETHYL)-N~3~-HYDROXY-6,8-DIOXA-3-AZABICYCLO[3.2.1]OCTANE-3,7-DICARBOXAMIDE, ACETOHYDROXAMIC ACID, CALCIUM ION, ... | 著者 | Mannino, C, Nievo, M, Machetti, F, Papakyriakou, A, Calderone, V, Fragai, M, Guarna, A. | 登録日 | 2006-07-26 | 公開日 | 2006-12-19 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.32 Å) | 主引用文献 | Synthesis of bicyclic molecular scaffolds (BTAa): an investigation towards new selective MMP-12 inhibitors. Bioorg.Med.Chem., 14, 2006
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6TVL
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![BU of 6tvl by Molmil](/molmil-images/mine/6tvl) | Hen Egg White Lysozyme in complex with a "half sandwich"-type Ru(II) coordination compound | 分子名称: | CHLORIDE ION, Lysozyme C, SODIUM ION, ... | 著者 | Chiniadis, L, Giastas, P, Bratsos, I, Papakyriakou, A. | 登録日 | 2020-01-10 | 公開日 | 2020-04-29 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.395 Å) | 主引用文献 | High-resolution crystal structures of a "half sandwich"-type Ru(II) coordination compound bound to hen egg-white lysozyme and proteinase K. J.Biol.Inorg.Chem., 25, 2020
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6TXG
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![BU of 6txg by Molmil](/molmil-images/mine/6txg) | Proteinase K in complex with a "half sandwich"-type Ru(II) coordination compound | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, NITRATE ION, ... | 著者 | Chiniadis, L, Giastas, P, Bratsos, I, Papakyriakou, A. | 登録日 | 2020-01-14 | 公開日 | 2020-04-29 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.372 Å) | 主引用文献 | High-resolution crystal structures of a "half sandwich"-type Ru(II) coordination compound bound to hen egg-white lysozyme and proteinase K. J.Biol.Inorg.Chem., 25, 2020
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7ZYF
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![BU of 7zyf by Molmil](/molmil-images/mine/7zyf) | Insulin regulated aminopeptidase (IRAP) in complex with a nanomolar alpha hydroxy beta amino acid based inhibitor. | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Mpakali, A, Stratikos, E, Giastas, P, Papakyriakou, A. | 登録日 | 2022-05-24 | 公開日 | 2022-07-20 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | 主引用文献 | Discovery of Selective Nanomolar Inhibitors for Insulin-Regulated Aminopeptidase Based on alpha-Hydroxy-beta-amino Acid Derivatives of Bestatin. J.Med.Chem., 65, 2022
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7Z28
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![BU of 7z28 by Molmil](/molmil-images/mine/7z28) | High-resolution crystal structure of ERAP1 with bound bestatin analogue inhibitor | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Giastas, P, Papakyriakou, A, Stratikos, E, Vourloumis, D. | 登録日 | 2022-02-26 | 公開日 | 2022-07-27 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Discovery of Selective Nanomolar Inhibitors for Insulin-Regulated Aminopeptidase Based on alpha-Hydroxy-beta-amino Acid Derivatives of Bestatin. J.Med.Chem., 65, 2022
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7BCX
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![BU of 7bcx by Molmil](/molmil-images/mine/7bcx) | The adduct of NAMI-A with Hen Egg White Lysozyme at 8 hours. | 分子名称: | CHLORIDE ION, DIMETHYL SULFOXIDE, IMIDAZOLE, ... | 著者 | Chiniadis, L, Giastas, P, Bratsos, I, Papakyriakou, A. | 登録日 | 2020-12-21 | 公開日 | 2021-07-28 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.06 Å) | 主引用文献 | Insights into the Protein Ruthenation Mechanism by Antimetastatic Metallodrugs: High-Resolution X-ray Structures of the Adduct Formed between Hen Egg-White Lysozyme and NAMI-A at Various Time Points. Inorg.Chem., 60, 2021
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7BDM
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![BU of 7bdm by Molmil](/molmil-images/mine/7bdm) | The adduct of NAMI-A with Hen Egg White Lysozyme at 98 hours. | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, Lysozyme, ... | 著者 | Chiniadis, L, Giastas, P, Bratsos, I, Papakyriakou, A. | 登録日 | 2020-12-22 | 公開日 | 2021-07-28 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.07 Å) | 主引用文献 | Insights into the Protein Ruthenation Mechanism by Antimetastatic Metallodrugs: High-Resolution X-ray Structures of the Adduct Formed between Hen Egg-White Lysozyme and NAMI-A at Various Time Points. Inorg.Chem., 60, 2021
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7BD0
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![BU of 7bd0 by Molmil](/molmil-images/mine/7bd0) | The adduct of NAMI-A with Hen Egg White Lysozyme at 26 hours. | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, IMIDAZOLE, ... | 著者 | Chiniadis, L, Giastas, P, Bratsos, I, Papakyriakou, A. | 登録日 | 2020-12-21 | 公開日 | 2021-07-28 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.06 Å) | 主引用文献 | Insights into the Protein Ruthenation Mechanism by Antimetastatic Metallodrugs: High-Resolution X-ray Structures of the Adduct Formed between Hen Egg-White Lysozyme and NAMI-A at Various Time Points. Inorg.Chem., 60, 2021
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7BCU
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![BU of 7bcu by Molmil](/molmil-images/mine/7bcu) | The adduct of NAMI-A with Hen Egg White Lysozyme at 1.5 hours. | 分子名称: | CHLORIDE ION, DIMETHYL SULFOXIDE, IMIDAZOLE, ... | 著者 | Chiniadis, L, Giastas, P, Bratsos, I, Papakyriakou, A. | 登録日 | 2020-12-21 | 公開日 | 2021-07-28 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (0.98 Å) | 主引用文献 | Insights into the Protein Ruthenation Mechanism by Antimetastatic Metallodrugs: High-Resolution X-ray Structures of the Adduct Formed between Hen Egg-White Lysozyme and NAMI-A at Various Time Points. Inorg.Chem., 60, 2021
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