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PDB: 7 件

7MEU
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BU of 7meu by Molmil
A biphenyl inhibitor of eIF4E targeting an internal binding site enables the design of cell-permeable PROTAC-degraders
分子名称: (2E)-2-{2-[4-([1,1'-biphenyl]-4-yl)-1,3-thiazol-2-yl]hydrazinylidene}-3-(2-nitrophenyl)propanoic acid, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, Eukaryotic translation initiation factor 4E
著者Papadopoulos, E.
登録日2021-04-07
公開日2021-04-28
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献A biphenyl inhibitor of eIF4E targeting an internal binding site enables the design of cell-permeable PROTAC-degraders.
Eur.J.Med.Chem., 219, 2021
4TQC
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BU of 4tqc by Molmil
The co-complex structure of the translation initiation factor eIF4E with the inhibitor 4EGI-1 reveals an allosteric mechanism for dissociating eIF4G
分子名称: (2S)-3-(4-amino-3-nitrophenyl)-2-{2-[4-(3,4-dichlorophenyl)-1,3-thiazol-2-yl]hydrazinyl}propanoic acid, 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE, Eukaryotic translation initiation factor 4E
著者Papadopoulos, E, Jenni, S, Wagner, G.
登録日2014-06-10
公開日2014-08-13
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of the eukaryotic translation initiation factor eIF4E in complex with 4EGI-1 reveals an allosteric mechanism for dissociating eIF4G.
Proc.Natl.Acad.Sci.USA, 111, 2014
4TQB
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BU of 4tqb by Molmil
The co-complex structure of the translation initiation factor eIF4E with the inhibitor 4EGI-1 reveals an allosteric mechanism for dissociating eIF4G
分子名称: (2E)-2-{2-[4-(4-bromophenyl)-1,3-thiazol-2-yl]hydrazinylidene}-3-(2-nitrophenyl)propanoic acid, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, ...
著者Papadopoulos, E, Jenni, S, Wagner, G.
登録日2014-06-10
公開日2014-08-13
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献Structure of the eukaryotic translation initiation factor eIF4E in complex with 4EGI-1 reveals an allosteric mechanism for dissociating eIF4G.
Proc.Natl.Acad.Sci.USA, 111, 2014
4TPW
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BU of 4tpw by Molmil
The co-complex structure of the translation initiation factor eIF4E with the inhibitor 4EGI-1 reveals an allosteric mechanism for dissociating eIF4G
分子名称: (2E)-2-{2-[4-(3,4-dichlorophenyl)-1,3-thiazol-2-yl]hydrazinylidene}-3-(2-nitrophenyl)propanoic acid, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, ...
著者Papadopoulos, E, Jenni, S, Wagner, G.
登録日2014-06-09
公開日2014-08-13
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structure of the eukaryotic translation initiation factor eIF4E in complex with 4EGI-1 reveals an allosteric mechanism for dissociating eIF4G.
Proc.Natl.Acad.Sci.USA, 111, 2014
2KZ8
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Solution NMR structure of MqsA, a protein from E. coli, containing a Zinc finger, N-terminal and a Helix Turn-Helix C-terminal domain
分子名称: Uncharacterized HTH-type transcriptional regulator ygiT
著者Papadopoulos, E, Vlamis-Gardikas, A, Graslund, A, Billeter, M, Holmgren, A, Collet, J.
登録日2010-06-14
公開日2011-06-29
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution structure and biophysical properties of MqsA, a Zn-containing antitoxin from Escherichia coli
Biochim.Biophys.Acta, 2012
1Z65
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Mouse Doppel 1-30 peptide
分子名称: Prion-like protein doppel
著者Papadopoulos, E.
登録日2005-03-21
公開日2006-02-07
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献NMR Solution Structure of the Peptide Fragment 1-30, Derived from Unprocessed Mouse Doppel Protein, in DHPC Micelles
Biochemistry, 45, 2006
2K44
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Solution structure of a K+-channel voltage-sensor paddle domain
分子名称: K+-channel voltage-sensor paddle domain of Calcium-activated potassium channel subunit alpha-1
著者Unnerstale, S, Lind, J, Papadopoulos, E, Maler, L.
登録日2008-05-28
公開日2009-06-02
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the HsapBK K+-channel voltage-sensor paddle sequence
Biochemistry, 2009

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件を2024-08-28に公開中

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