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PDB: 558 results

6VM0
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Full length Glycine receptor reconstituted in lipid nanodisc in Gly/IVM-conformation (State-1)
Descriptor: (2aE,4E,5'S,6S,6'R,7S,8E,11R,13R,15S,17aR,20R,20aR,20bS)-6'-[(2S)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17 -oxo-3',4',5',6,6',10,11,14,15,17,17a,20,20a,20b-tetradecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacy clooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl)-3-O-methyl-alpha-L-arabino-hexopyranoside, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCINE, ...
Authors:Kumar, A, Basak, S, Chakrapani, S.
Deposit date:2020-01-27
Release date:2020-07-29
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.14 Å)
Cite:Mechanisms of activation and desensitization of full-length glycine receptor in lipid nanodiscs.
Nat Commun, 11, 2020
6VM2
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BU of 6vm2 by Molmil
Full length Glycine receptor reconstituted in lipid nanodisc in Gly/IVM-conformation (State-2)
Descriptor: (2aE,4E,5'S,6S,6'R,7S,8E,11R,13R,15S,17aR,20R,20aR,20bS)-6'-[(2S)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17 -oxo-3',4',5',6,6',10,11,14,15,17,17a,20,20a,20b-tetradecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacy clooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl)-3-O-methyl-alpha-L-arabino-hexopyranoside, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCINE, ...
Authors:Kumar, A, Basak, S, Chakrapani, S.
Deposit date:2020-01-27
Release date:2020-07-29
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.34 Å)
Cite:Mechanisms of activation and desensitization of full-length glycine receptor in lipid nanodiscs.
Nat Commun, 11, 2020
6W1Y
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BU of 6w1y by Molmil
Cryo-EM structure of 5HT3A receptor in presence of Palonosetron
Descriptor: (3~{a}~{S})-2-[(3~{S})-1-azabicyclo[2.2.2]octan-3-yl]-3~{a},4,5,6-tetrahydro-3~{H}-benzo[de]isoquinolin-1-one, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(4-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Basak, S, Chakrapani, S.
Deposit date:2020-03-04
Release date:2021-01-13
Method:ELECTRON MICROSCOPY (3.35 Å)
Cite:High-resolution structures of multiple 5-HT 3A R-setron complexes reveal a novel mechanism of competitive inhibition.
Elife, 9, 2020
6VM3
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BU of 6vm3 by Molmil
Full length Glycine receptor reconstituted in lipid nanodisc in Gly/IVM-conformation (State-3)
Descriptor: (2aE,4E,5'S,6S,6'R,7S,8E,11R,13R,15S,17aR,20R,20aR,20bS)-6'-[(2S)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17 -oxo-3',4',5',6,6',10,11,14,15,17,17a,20,20a,20b-tetradecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacy clooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl)-3-O-methyl-alpha-L-arabino-hexopyranoside, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCINE, ...
Authors:Kumar, A, Basak, S, Chakrapani, S.
Deposit date:2020-01-27
Release date:2020-07-29
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.07 Å)
Cite:Mechanisms of activation and desensitization of full-length glycine receptor in lipid nanodiscs.
Nat Commun, 11, 2020
4Q13
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BU of 4q13 by Molmil
Apo Estrogen Receptor Alpha Ligand Binding Domain D538G Mutant with a glucocorticoid receptor-interacting protein 1 NR box II peptide
Descriptor: Estrogen receptor, Glucocorticoid receptor-interacting protein 1 NR box II peptide
Authors:Fanning, S.W, Panchamukhi, S, Greene, G.L.
Deposit date:2014-04-02
Release date:2015-04-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:Estrogen receptor alpha somatic mutations Y537S and D538G confer breast cancer endocrine resistance by stabilizing the activating function-2 binding conformation.
Elife, 5, 2016
4PXM
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BU of 4pxm by Molmil
The Estrogen Receptor Alpha Ligand Binding Domain D538G Mutant in Complex with Estradiol and a glucocorticoid receptor-interacting protein 1 NR box II peptide
Descriptor: ESTRADIOL, Estrogen receptor, Nuclear receptor coactivator 2
Authors:Fanning, S.W, Panchamukhi, S, Greene, G.L.
Deposit date:2014-03-24
Release date:2015-04-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Estrogen receptor alpha somatic mutations Y537S and D538G confer breast cancer endocrine resistance by stabilizing the activating function-2 binding conformation.
Elife, 5, 2016
6OJ6
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BU of 6oj6 by Molmil
In situ structure of rotavirus VP1 RNA-dependent RNA polymerase (DLP_RNA)
Descriptor: Inner capsid protein VP2, RNA-directed RNA polymerase, Template, ...
Authors:Jenni, S, Salgado, E.N, Herrmann, T, Li, Z, Grant, T, Grigorieff, N, Trapani, S, Estrozi, L.F, Harrison, S.C.
Deposit date:2019-04-10
Release date:2019-04-24
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:In situ Structure of Rotavirus VP1 RNA-Dependent RNA Polymerase.
J.Mol.Biol., 431, 2019
1XWR
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BU of 1xwr by Molmil
Crystal structure of the coliphage lambda transcription activator protein CII
Descriptor: ISOPROPYL ALCOHOL, Regulatory protein CII
Authors:Datta, A.B, Panjikar, S, Weiss, M.S, Chakrabarti, P, Parrack, P.
Deposit date:2004-11-02
Release date:2005-06-21
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:Structure of {lambda} CII: Implications for recognition of direct-repeat DNA by an unusual tetrameric organization
Proc.Natl.Acad.Sci.USA, 102, 2005
5IRA
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BU of 5ira by Molmil
Expanding Nature's Catalytic Repertoire -Directed Evolution of an Artificial Metalloenzyme for In Vivo Metathesis
Descriptor: Artificial Metathesase, [1-[4-[[5-[(3~{a}~{S},4~{S},6~{a}~{R})-2-oxidanylidene-1,3,3~{a},4,6,6~{a}-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoylamino]methyl]-2,6-dimethyl-phenyl]-3-(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-1-ium-2-yl]-bis(chloranyl)ruthenium
Authors:Heinisch, T, Jeschek, M, Reuter, R, Trindler, C, Panke, S, Ward, T.R.
Deposit date:2016-03-12
Release date:2016-08-31
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Directed evolution of artificial metalloenzymes for in vivo metathesis.
Nature, 537, 2016
2ALG
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BU of 2alg by Molmil
Crystal structure of peach Pru p3, the prototypic member of the family of plant non-specific lipid transfer protein pan-allergens
Descriptor: HEPTANE, HEXAETHYLENE GLYCOL, LAURIC ACID, ...
Authors:Pasquato, N, Berni, R, Folli, C, Folloni, S, Cianci, M, Pantano, S, Helliwell, J, Zanotti, G.
Deposit date:2005-08-05
Release date:2005-11-29
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structure of Peach Pru p 3, the Prototypic Member of the Family of Plant Non-specific Lipid Transfer Protein Pan-allergens
J.Mol.Biol., 356, 2006
2A7A
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BU of 2a7a by Molmil
On the Routine Use of Soft X-Rays in Macromolecular Crystallography, Part III- The Optimal Data Collection Wavelength
Descriptor: CALCIUM ION, Concanavalin A, MANGANESE (II) ION, ...
Authors:Mueller-Dieckmann, C, Panjikar, S, Tucker, P.A, Weiss, M.S.
Deposit date:2005-07-05
Release date:2005-07-19
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:On the routine use of soft X-rays in macromolecular crystallography. Part III. The optimal data-collection wavelength.
Acta Crystallogr.,Sect.D, 61, 2005
6BE1
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BU of 6be1 by Molmil
Cryo-EM structure of serotonin receptor
Descriptor: 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Basak, S, Chakrapani, S.
Deposit date:2017-10-24
Release date:2018-02-07
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (4.31 Å)
Cite:Cryo-EM structure of 5-HT
Nat Commun, 9, 2018
6B5V
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BU of 6b5v by Molmil
Structure of TRPV5 in complex with econazole
Descriptor: 1-[(2R)-2-[(4-chlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole, CALCIUM ION, Transient receptor potential cation channel subfamily V member 5
Authors:Hughes, T.E.T, Lodowski, D.T, Huynh, K.W, Yazici, A, del Rosario, J, Kapoor, A, Basak, S, Samanta, A, Chakrapani, S, Zhou, Z.H, Filizola, M, Rohacs, T, Han, S, Moiseenkova-Bell, V.Y.
Deposit date:2017-09-29
Release date:2017-12-27
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Structural basis of TRPV5 channel inhibition by econazole revealed by cryo-EM.
Nat. Struct. Mol. Biol., 25, 2018
3P5C
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BU of 3p5c by Molmil
The structure of the LDLR/PCSK9 complex reveals the receptor in an extended conformation
Descriptor: CALCIUM ION, Low density lipoprotein receptor variant, Proprotein convertase subtilisin/kexin type 9
Authors:Lo Surdo, P, Bottomley, M.J, Calzetta, A, Settembre, E.C, Cirillo, A, Pandit, S, Ni, Y, Hubbard, B, Sitlani, A, Carfi, A.
Deposit date:2010-10-08
Release date:2011-10-26
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (4.2 Å)
Cite:Mechanistic implications for LDL receptor degradation from the PCSK9/LDLR structure at neutral pH.
Embo Rep., 12, 2011
3P86
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BU of 3p86 by Molmil
Crystal structure of CTR1 kinase domain mutant D676N in complex with staurosporine
Descriptor: STAUROSPORINE, Serine/threonine-protein kinase CTR1
Authors:Mayerhofer, H, Panneerselvam, S, Mueller-Dieckmann, J.
Deposit date:2010-10-13
Release date:2011-10-26
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.496 Å)
Cite:Protein kinase domain of CTR1 from Arabidopsis thaliana promotes ethylene receptor cross talk.
J. Mol. Biol., 415, 2012
3PPZ
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BU of 3ppz by Molmil
Crystal structure of CTR1 kinase domain in complex with staurosporine
Descriptor: STAUROSPORINE, Serine/threonine-protein kinase CTR1
Authors:Mayerhofer, H, Panneerselvam, S, Mueller-Dieckmann, J.
Deposit date:2010-11-25
Release date:2011-12-07
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.99 Å)
Cite:Protein kinase domain of CTR1 from Arabidopsis thaliana promotes ethylene receptor cross talk.
J. Mol. Biol., 415, 2012
1K0M
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BU of 1k0m by Molmil
Crystal structure of a soluble monomeric form of CLIC1 at 1.4 angstroms
Descriptor: CHLORIDE INTRACELLULAR CHANNEL PROTEIN 1
Authors:Harrop, S.J, DeMaere, M.Z, Fairlie, W.D, Reztsova, T, Valenzuela, S.M, Mazzanti, M, Tonini, R, Qiu, M.R, Jankova, L, Warton, K, Bauskin, A.R, Wu, W.M, Pankhurst, S, Campbell, T.J, Breit, S.N, Curmi, P.M.G.
Deposit date:2001-09-19
Release date:2001-12-12
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal structure of a soluble form of the intracellular chloride ion channel CLIC1 (NCC27) at 1.4-A resolution.
J.Biol.Chem., 276, 2001
2Y26
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BU of 2y26 by Molmil
Transmission defective mutant of Grapevine Fanleaf virus
Descriptor: COAT PROTEIN
Authors:Schellenberger, P, Sauter, C, Lorber, B, Bron, P, Trapani, S, Bergdoll, M, Marmonier, A, Schmitt-Keichinger, C, Lemaire, O, Demangeat, G, Ritzenthaler, C.
Deposit date:2010-12-13
Release date:2011-06-08
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural Insights Into Viral Determinants of Nematode Mediated Grapevine Fanleaf Virus Transmission.
Plos Pathog., 7, 2011
1K0O
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BU of 1k0o by Molmil
Crystal structure of a soluble form of CLIC1. An intracellular chloride ion channel
Descriptor: CHLORIDE INTRACELLULAR CHANNEL PROTEIN 1
Authors:Harrop, S.J, DeMaere, M.Z, Fairlie, W.D, Reztsova, T, Valenzuela, S.M, Mazzanti, M, Tonini, R, Qiu, M.R, Jankova, L, Warton, K, Bauskin, A.R, Wu, W.M, Pankhurst, S, Campbell, T.J, Breit, S.N, Curmi, P.M.G.
Deposit date:2001-09-19
Release date:2001-12-12
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structure of a soluble form of the intracellular chloride ion channel CLIC1 (NCC27) at 1.4-A resolution.
J.Biol.Chem., 276, 2001
1K0N
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BU of 1k0n by Molmil
Chloride Intracellular Channel 1 (CLIC1) complexed with glutathione
Descriptor: CHLORIDE INTRACELLULAR CHANNEL PROTEIN 1, GLUTATHIONE
Authors:Harrop, S.J, DeMaere, M.Z, Fairlie, W.D, Reztsova, T, Valenzuela, S.M, Mazzanti, M, Tonini, R, Qiu, M.R, Jankova, L, Warton, K, Bauskin, A.R, Wu, W.M, Pankhurst, S, Campbell, T.J, Breit, S.N, Curmi, P.M.G.
Deposit date:2001-09-19
Release date:2001-12-12
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of a soluble form of the intracellular chloride ion channel CLIC1 (NCC27) at 1.4-A resolution.
J.Biol.Chem., 276, 2001
6DG8
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BU of 6dg8 by Molmil
Full-length 5-HT3A receptor in a serotonin-bound conformation- State 2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5-hydroxytryptamine receptor 3A, SEROTONIN, ...
Authors:Basak, S, Chakrapani, S.
Deposit date:2018-05-17
Release date:2018-11-07
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.89 Å)
Cite:Cryo-EM reveals two distinct serotonin-bound conformations of full-length 5-HT3Areceptor.
Nature, 563, 2018
6DG7
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BU of 6dg7 by Molmil
Full-length 5-HT3A receptor in a serotonin-bound conformation- State 1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5-hydroxytryptamine receptor 3A, SEROTONIN, ...
Authors:Basak, S, Chakrapani, S.
Deposit date:2018-05-17
Release date:2018-11-07
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.32 Å)
Cite:Cryo-EM reveals two distinct serotonin-bound conformations of full-length 5-HT3Areceptor.
Nature, 563, 2018
1Y64
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BU of 1y64 by Molmil
Bni1p Formin Homology 2 Domain complexed with ATP-actin
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Otomo, T, Tomchick, D.R, Otomo, C, Panchal, S.C, Machius, M, Rosen, M.K.
Deposit date:2004-12-03
Release date:2005-01-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Structural basis of actin filament nucleation and processive capping by a formin homology 2 domain
Nature, 433, 2005
3P5B
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BU of 3p5b by Molmil
The structure of the LDLR/PCSK9 complex reveals the receptor in an extended conformation
Descriptor: CALCIUM ION, Low density lipoprotein receptor variant, Proprotein convertase subtilisin/kexin type 9
Authors:Lo Surdo, P, Bottomley, M.J, Calzetta, A, Settembre, E.C, Cirillo, A, Pandit, S, Ni, Y, Hubbard, B, Sitlani, A, Carfi, A.
Deposit date:2010-10-08
Release date:2011-10-26
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Mechanistic implications for LDL receptor degradation from the PCSK9/LDLR structure at neutral pH.
Embo Rep., 12, 2011
2A7J
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BU of 2a7j by Molmil
On the Routine Use of Soft X-Rays in Macromolecular Crystallography, Part III- The Optimal Data Collection Wavelength
Descriptor: ACETATE ION, CALCIUM ION, CHLORIDE ION, ...
Authors:Mueller-Dieckmann, C, Panjikar, S, Tucker, P.A, Weiss, M.S.
Deposit date:2005-07-05
Release date:2005-07-19
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:On the routine use of soft X-rays in macromolecular crystallography. Part III. The optimal data-collection wavelength.
Acta Crystallogr.,Sect.D, 61, 2005

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