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PDB: 89 results
3V07
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BU of 3v07 by Molmil
Crystal structure of R-6'-Me-3'-fluoro hexitol nucleic acid
Descriptor: DNA (5'-D(*GP*CP*GP*TP*AP*(F6H)P*AP*CP*GP*C)-3')
Authors:Pallan, P.S, Egli, M.
Deposit date:2011-12-07
Release date:2012-02-08
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.24 Å)
Cite:Insights from crystal structures into the opposite effects on RNA affinity caused by the s- and R-6'-methyl backbone modifications of 3'-fluoro hexitol nucleic Acid.
Biochemistry, 51, 2012
3EY3
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BU of 3ey3 by Molmil
A Conformational Transition in the Structure of a 2'-Thiomethyl-Modified DNA Visualized at High Resolution
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 5'-D(*CP*GP*CP*GP*AP*AP*(USM)P*(USM)P*CP*GP*CP*G)-3', STRONTIUM ION
Authors:Egli, M, Pallan, P.S.
Deposit date:2008-10-17
Release date:2009-04-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:A conformational transition in the structure of a 2'-thiomethyl-modified DNA visualized at high resolution.
Chem.Commun.(Camb.), 15, 2009
3EY2
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BU of 3ey2 by Molmil
A Conformational Transition in the Structure of a 2'-Thiomethyl-Modified DNA Visualized at High Resolution
Descriptor: 5'-D(*GP*CP*GP*TP*AP*(USM)P*AP*CP*GP*C)-3', N-methylpropane-1,3-diamine
Authors:Egli, M, Pallan, P.S.
Deposit date:2008-10-17
Release date:2009-04-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.04 Å)
Cite:A conformational transition in the structure of a 2'-thiomethyl-modified DNA visualized at high resolution.
Chem.Commun.(Camb.), 15, 2009
2M11
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BU of 2m11 by Molmil
Structure of perimidinone-derived synthetic nucleoside paired with guanine in DNA duplex
Descriptor: DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*(D3N)P*GP*CP*G)-3')
Authors:Kowal, E.A, Lad, R, Pallan, P.S, Muffly, E, Wawrzak, Z, Egli, M, Sturla, S.J, Stone, M.P.
Deposit date:2012-11-09
Release date:2013-06-12
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Recognition of O6-benzyl-2'-deoxyguanosine by a perimidinone-derived synthetic nucleoside: a DNA interstrand stacking interaction.
Nucleic Acids Res., 41, 2013
1Y84
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BU of 1y84 by Molmil
Crystal structure of the A-DNA GCGTAT*CGC with a 2'-O-[2-(imidazolyl)ethyl] Thymidine (T*)
Descriptor: 5'-D(*GP*CP*GP*TP*AP*(EIT)P*AP*CP*GP*C)-3', MAGNESIUM ION, SPERMINE
Authors:Egli, M, Minasov, G, Tereshko, V, Pallan, P.S, Teplova, M, Inamati, G.B, Lesnik, E.A, Owens, S.R, Ross, B.S, Prakash, T.P, Manoharan, M.
Deposit date:2004-12-10
Release date:2005-06-28
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Probing the Influence of Stereoelectronic Effects on the Biophysical Properties of Oligonucleotides: Comprehensive Analysis of the RNA Affinity, Nuclease Resistance, and Crystal Structure of Ten 2'-O-Ribonucleic Acid Modifications.
Biochemistry, 44, 2005
1Y8L
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BU of 1y8l by Molmil
Crystal structure of the A-DNA GCGTAT*CGC with a 2'-O-[2-(trifluoro)ethyl] Thymidine (T*)
Descriptor: 5'-D(*GP*CP*GP*TP*AP*(TFE)P*AP*CP*GP*C)-3'), MAGNESIUM ION, SPERMINE
Authors:Egli, M, Minasov, G, Tereshko, V, Pallan, P.S, Teplova, M, Inamati, G.B, Lesnik, E.A, Owens, S.R, Ross, B.S, Prakash, T.P, Manoharan, M.
Deposit date:2004-12-13
Release date:2005-06-28
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Probing the Influence of Stereoelectronic Effects on the Biophysical Properties of Oligonucleotides: Comprehensive Analysis of the RNA Affinity, Nuclease Resistance, and Crystal Structure of Ten 2'-O-Ribonucleic Acid Modifications.
Biochemistry, 44, 2005
1Y7F
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BU of 1y7f by Molmil
Crystal structure of the A-DNA GCGTAT*CGC with a 2'-O-[2-[hydroxy(methyleneamino)oxy]ethyl] Thymidine (T*)
Descriptor: 5'-D(*GP*CP*GP*TP*AP*(2NT)P*AP*CP*GP*C)-3'), BARIUM ION
Authors:Egli, M, Minasov, G, Tereshko, V, Pallan, P.S, Teplova, M, Inamati, G.B, Lesnik, E.A, Owens, S.R, Ross, B.S, Prakash, T.P, Manoharan, M.
Deposit date:2004-12-08
Release date:2005-06-28
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Probing the Influence of Stereoelectronic Effects on the Biophysical Properties of Oligonucleotides: Comprehensive Analysis of the RNA Affinity, Nuclease Resistance, and Crystal Structure of Ten 2'-O-Ribonucleic Acid Modifications.
Biochemistry, 44, 2005
1YB9
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BU of 1yb9 by Molmil
Crystal structure of the A-DNA GCGTAT*CGC with a 2'-O-[2-(N,N-dimethylaminooxy)ethyl] Thymidine (T*)
Descriptor: 5'-D(*GP*CP*GP*TP*AP*(2OT)P*AP*CP*GP*C)-3'), SPERMINE
Authors:Egli, M, Minasov, G, Tereshko, V, Pallan, P.S, Teplova, M, Inamati, G.B, Lesnik, E.A, Owens, S.R, Ross, B.S, Prakash, T.P, Manoharan, M.
Deposit date:2004-12-20
Release date:2005-06-28
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Probing the Influence of Stereoelectronic Effects on the Biophysical Properties of Oligonucleotides: Comprehensive Analysis of the RNA Affinity, Nuclease Resistance, and Crystal Structure of Ten 2'-O-Ribonucleic Acid Modifications.
Biochemistry, 44, 2005
1Y8V
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BU of 1y8v by Molmil
Crystal structure of the A-DNA GCGTAT*CGC with a 2'-O-propyl Thymidine (T*)
Descriptor: 5'-D(*GP*CP*GP*TP*AP*(P2T)P*AP*CP*GP*C)-3'
Authors:Egli, M, Minasov, G, Tereshko, V, Pallan, P.S, Teplova, M, Inamati, G.B, Lesnik, E.A, Owens, S.R, Ross, B.S, Prakash, T.P, Manoharan, M.
Deposit date:2004-12-13
Release date:2005-06-28
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Probing the Influence of Stereoelectronic Effects on the Biophysical Properties of Oligonucleotides: Comprehensive Analysis of the RNA Affinity, Nuclease Resistance, and Crystal Structure of Ten 2'-O-Ribonucleic Acid Modifications.
Biochemistry, 44, 2005
1Y86
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BU of 1y86 by Molmil
Crystal structure of the A-DNA GCGTAT*CGC with a 2'-O-[2-(fluoro)ethyl] Thymidine (T*)
Descriptor: 5'-D(*GP*CP*GP*TP*AP*(125)P*AP*CP*GP*C)-3'
Authors:Egli, M, Minasov, G, Tereshko, V, Pallan, P.S, Teplova, M, Inamati, G.B, Lesnik, E.A, Owens, S.R, Ross, B.S, Prakash, T.P, Manoharan, M.
Deposit date:2004-12-10
Release date:2005-06-28
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Probing the Influence of Stereoelectronic Effects on the Biophysical Properties of Oligonucleotides: Comprehensive Analysis of the RNA Affinity, Nuclease Resistance, and Crystal Structure of Ten 2'-O-Ribonucleic Acid Modifications.
Biochemistry, 44, 2005
1Y9F
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BU of 1y9f by Molmil
Crystal structure of the A-DNA GCGTAT*CGC with a 2'-O-allyl Thymidine (T*)
Descriptor: 5'-D(*GP*CP*GP*TP*AP*(2AT)P*AP*CP*GP*C)-3')
Authors:Egli, M, Minasov, G, Tereshko, V, Pallan, P.S, Teplova, M, Inamati, G.B, Lesnik, E.A, Owens, S.R, Ross, B.S, Prakash, T.P, Manoharan, M.
Deposit date:2004-12-15
Release date:2005-06-28
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Probing the Influence of Stereoelectronic Effects on the Biophysical Properties of Oligonucleotides: Comprehensive Analysis of the RNA Affinity, Nuclease Resistance, and Crystal Structure of Ten 2'-O-Ribonucleic Acid Modifications.
Biochemistry, 44, 2005
7UCR
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BU of 7ucr by Molmil
Joint X-ray/neutron structure of the Sarcin-Ricin loop RNA
Descriptor: SULFATE ION, Sarcin-Ricin loop RNA
Authors:Harp, J.M, Egli, M.E, Pallan, P.S, Coates, L.
Deposit date:2022-03-17
Release date:2022-07-20
Last modified:2024-04-03
Method:NEUTRON DIFFRACTION (1 Å), X-RAY DIFFRACTION
Cite:Cryo neutron crystallography demonstrates influence of RNA 2'-OH orientation on conformation, sugar pucker and water structure.
Nucleic Acids Res., 50, 2022
2A0P
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BU of 2a0p by Molmil
Crystal structure of RNA oligomer containing 4'-thioribose
Descriptor: 5'-R(*CP*CP*(S4C)P*CP*GP*GP*GP*G)-3'
Authors:Haeberli, P, Berger, I, Pallan, P.S, Egli, M.
Deposit date:2005-06-16
Release date:2005-08-16
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Syntheses of 4'-thioribonucleosides and thermodynamic stability and crystal structure of RNA oligomers with incorporated 4'-thiocytosine
Nucleic Acids Res., 33, 2005
2H9S
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BU of 2h9s by Molmil
Crystal Structure of Homo-DNA and Nature's Choice of Pentose over Hexose in the Genetic System
Descriptor: 5'-D(*(XCT)P*(XGU)P*(XAD)P*(XAD)P*(XTH)P*(XTH)P*(XCT)P*(XGU))-3', MAGNESIUM ION
Authors:Egli, M, Pallan, P.S.
Deposit date:2006-06-11
Release date:2006-12-12
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structure of homo-DNA and nature's choice of pentose over hexose in the genetic system.
J.Am.Chem.Soc., 128, 2006
7JJF
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BU of 7jjf by Molmil
Sarcin-ricin loop with modified residue.
Descriptor: MAGNESIUM ION, RNA/DNA (27-mer)
Authors:Harp, J.M, Pallan, P.S, Egli, M.
Deposit date:2020-07-25
Release date:2020-12-23
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Incorporating a Thiophosphate Modification into a Common RNA Tetraloop Motif Causes an Unanticipated Stability Boost.
Biochemistry, 59, 2020
3HR3
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BU of 3hr3 by Molmil
Interplay of Structure, Hydration and Thermal Stability in Formacetal Modified Oligonucleotides: RNA May Tolerate Hydrophobic Modifications Better than DNA
Descriptor: 5'-D(*GP*CP*GP*(US4)P*(OMU))P*AP*CP*GP*C)-3'
Authors:Egli, M, Pallan, P.S.
Deposit date:2009-06-08
Release date:2009-10-27
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Interplay of structure, hydration and thermal stability in formacetal modified oligonucleotides: RNA may tolerate nonionic modifications better than DNA.
J.Am.Chem.Soc., 131, 2009
3EY1
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BU of 3ey1 by Molmil
A Conformational Transition in the Structure of a 2'-Thiomethyl-Modified DNA Visualized at High Resolution
Descriptor: 5'-D(*CP*GP*CP*GP*AP*AP*(USM)P*(USM)P*CP*GP*CP*G)-3', GLYCEROL, Ribonuclease H
Authors:Egli, M, Pallan, P.S.
Deposit date:2008-10-17
Release date:2009-04-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:A conformational transition in the structure of a 2'-thiomethyl-modified DNA visualized at high resolution.
Chem.Commun.(Camb.), 15, 2009
3I8D
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BU of 3i8d by Molmil
The Pairing Geometry of the Hydrophobic Thymine Analog 2,4-Difluorotoluene in Duplex DNA as Analyzed by X-ray Crystallography
Descriptor: 5'-D(*CP*GP*CP*GP*AP*AP*TP*(DFT)P*CP*GP*CP*G)-3', GLYCEROL, Ribonuclease H
Authors:Egli, M, Pallan, P.S.
Deposit date:2009-07-09
Release date:2009-09-01
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:Pairing geometry of the hydrophobic thymine analogue 2,4-difluorotoluene in duplex DNA as analyzed by X-ray crystallography.
J.Am.Chem.Soc., 131, 2009
4DKZ
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BU of 4dkz by Molmil
Hairpin structure of a DNA dodecamer containing North-methanocarba-2'-deoxythymidine
Descriptor: Synthetic DNA dodecamer containg North-methanocarba-2'-deoxythymidine (N-MCdT)
Authors:Egli, M, Pallan, P.S.
Deposit date:2012-02-05
Release date:2012-03-28
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The Conformationally Constrained N-Methanocarba-dT Analogue Adopts an Unexpected C4'-exo Sugar Pucker in the Structure of a DNA Hairpin.
Biochemistry, 51, 2012
4PWM
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BU of 4pwm by Molmil
Crystal structure of Dickerson Drew Dodecamer with 5-carboxycytosine
Descriptor: 5'-[CGCGAATT(5CC)GCG]-3'
Authors:Szulik, M.W, Pallan, P, Banerjee, S, Voehler, M, Egli, M, Stone, M.P.
Deposit date:2014-03-20
Release date:2015-02-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Differential stabilities and sequence-dependent base pair opening dynamics of watson-crick base pairs with 5-hydroxymethylcytosine, 5-formylcytosine, or 5-carboxylcytosine.
Biochemistry, 54, 2015
4QC7
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BU of 4qc7 by Molmil
Dodecamer structure of 5-formylcytosine containing DNA
Descriptor: short DNA strands
Authors:Szulik, M.W, Pallan, P, Egli, M, Stone, M.P.
Deposit date:2014-05-09
Release date:2015-02-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Differential stabilities and sequence-dependent base pair opening dynamics of watson-crick base pairs with 5-hydroxymethylcytosine, 5-formylcytosine, or 5-carboxylcytosine.
Biochemistry, 54, 2015
1WV6
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BU of 1wv6 by Molmil
X-ray structure of the A-decamer GCGTATACGC with a single 2'-O-butyl thymine in place of T6, Sr-form
Descriptor: 5'-D(*GP*CP*GP*TP*AP*(2BT)P*AP*CP*GP*C)-3', STRONTIUM ION
Authors:Egli, M, Minasov, G, Tereshko, V, Pallan, P.S, Teplova, M, Inamati, G.B, Lesnik, E.A, Owens, S.R, Ross, B.S, Prakash, T.P, Manoharam, M.
Deposit date:2004-12-11
Release date:2005-06-28
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Probing the influence of stereoelectronic effects on the biophysical properties of oligonucleotides: comprehensive analysis of the RNA affinity, nuclease resistance, and crystal structure of ten 2'-O-ribonucleic acid modifications.
Biochemistry, 44, 2005
1WV5
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BU of 1wv5 by Molmil
X-ray structure of the A-decamer GCGTATACGC with a single 2'-o-butyl thymine in place of T6, Mg-form
Descriptor: 5'-D(*GP*CP*GP*TP*AP*(2BT)P*AP*CP*GP*C)-3', MAGNESIUM ION
Authors:Egli, M, Minasov, G, Tereshko, V, Pallan, P.S, Teplova, M, Inamati, G.B, Lesnik, E.A, Owens, S.R, Ross, B.S, Prakash, T.P, Manoharam, M.
Deposit date:2004-12-11
Release date:2005-06-28
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Probing the influence of stereoelectronic effects on the biophysical properties of oligonucleotides: comprehensive analysis of the RNA affinity, nuclease resistance, and crystal structure of ten 2'-O-ribonucleic acid modifications.
Biochemistry, 44, 2005
1Y9S
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BU of 1y9s by Molmil
Crystal structure of the A-DNA GCGTAT*CGC with a 2'-O-propargyl Thymidine (T*)
Descriptor: 5'-D(*GP*CP*GP*TP*AP*(2GT)P*AP*CP*GP*C)-3')
Authors:Egli, M, Minasov, G, Tereshko, V, Pallan, P.S, Teplova, M, Inamati, G.B, Lesnik, E.A, Owens, S.R, Ross, B.S, Prakash, T.P, Manoharan, M.
Deposit date:2004-12-16
Release date:2005-06-28
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Probing the Influence of Stereoelectronic Effects on the Biophysical Properties of Oligonucleotides: Comprehensive Analysis of the RNA Affinity, Nuclease Resistance, and Crystal Structure of Ten 2'-O-Ribonucleic Acid Modifications.
Biochemistry, 44, 2005
1YBC
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BU of 1ybc by Molmil
Crystal structure of the A-DNA GCGTAT*CGC with a 2'-O-[2-(benzyloxy)ethyl] Thymidine (T*)
Descriptor: 5'-D(*GP*CP*GP*TP*AP*(BOE)P*AP*CP*GP*C)-3'), STRONTIUM ION
Authors:Egli, M, Minasov, G, Tereshko, V, Pallan, P.S, Teplova, M, Inamati, G.B, Lesnik, E.A, Owens, S.R, Ross, B.S, Prakash, T.P, Manoharan, M.
Deposit date:2004-12-20
Release date:2005-06-28
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Probing the Influence of Stereoelectronic Effects on the Biophysical Properties of Oligonucleotides: Comprehensive Analysis of the RNA Affinity, Nuclease Resistance, and Crystal Structure of Ten 2'-O-Ribonucleic Acid Modifications.
Biochemistry, 44, 2005

224931

數據於2024-09-11公開中

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