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PDB: 2 件

5UQ0
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BU of 5uq0 by Molmil
FGFR1 kinase domain complex with fragment 2,2-dimethyl-2,3-dihydrobenzofuran-7-carboxamide
分子名称: 2,2-dimethyl-2,3-dihydro-1-benzofuran-7-carboxamide, Fibroblast growth factor receptor 1
著者Paik, W.-K, Squire, C.J.
登録日2017-02-05
公開日2017-02-22
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Fragment screening diverse active sites
To Be Published
5UR1
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BU of 5ur1 by Molmil
FGFR1 kinase domain complex with SN37333 in reversible binding mode
分子名称: 3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-{1-[4-(dimethylamino)but-2-enoyl]piperidin-4-yl}-7-(phenylamino)-3,4-dihydropyrimido[4,5-d]pyrimidin-2(1H)-one, Fibroblast growth factor receptor 1
著者Yosaatmadja, Y, Paik, W.-K, Smaill, J.B, Squire, C.J.
登録日2017-02-09
公開日2017-05-31
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献2-Oxo-3, 4-dihydropyrimido[4, 5-d]pyrimidinyl derivatives as new irreversible pan fibroblast growth factor receptor (FGFR) inhibitors.
Eur J Med Chem, 135, 2017

223166

件を2024-07-31に公開中

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