6L9L
| 1D4 TCR recognition of H2-Ld a1a2 A5 Peptide Complexes | Descriptor: | H2-Ld a1a2, SER-PRO-SER-TYR-ALA-TYR-HIS-GLN-PHE, T Cell Receptor | Authors: | Wei, P.C, Yin, L. | Deposit date: | 2019-11-10 | Release date: | 2020-11-18 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.399 Å) | Cite: | Structures suggest an approach for converting weak self-peptide tumor antigens into superagonists for CD8 T cells in cancer. Proc.Natl.Acad.Sci.USA, 118, 2021
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6L1S
| Crystal structure of DUSP22 mutant_C88S | Descriptor: | Dual specificity protein phosphatase 22, PHOSPHATE ION | Authors: | Lai, C.H, Chang, C.C, Lyu, P.C. | Deposit date: | 2019-09-30 | Release date: | 2020-10-28 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.3611 Å) | Cite: | Structural Insights into the Active Site Formation of DUSP22 in N-loop-containing Protein Tyrosine Phosphatases. Int J Mol Sci, 21, 2020
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6L9M
| H2-Ld complexed with AH1 peptide | Descriptor: | H2-Ld, SER-PRO-SER-TYR-VAL-TYR-HIS-GLN-PHE, b2m | Authors: | Wei, P.C, Yin, L. | Deposit date: | 2019-11-10 | Release date: | 2020-11-18 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structures suggest an approach for converting weak self-peptide tumor antigens into superagonists for CD8 T cells in cancer. Proc.Natl.Acad.Sci.USA, 118, 2021
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8WD5
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7EJB
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8W35
| Aca2 from Pectobacterium phage ZF40 bound to RNA | Descriptor: | Anti-CRISPR associated (Aca) protein, Aca2, IR2 and IR-RBS RNA | Authors: | Wilkinson, M.E, Birkholz, N, Kimanius, D, Fineran, P.C. | Deposit date: | 2024-02-21 | Release date: | 2024-07-24 | Last modified: | 2024-08-14 | Method: | ELECTRON MICROSCOPY (2.61 Å) | Cite: | Phage anti-CRISPR control by an RNA- and DNA-binding helix-turn-helix protein. Nature, 631, 2024
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8VLM
| Crystal structure of the yeast cytosine deaminase (yCD) E64V-M100W heterodimer | Descriptor: | 1,2-ETHANEDIOL, Cytosine deaminase, ZINC ION | Authors: | Picard, M.-E, Grenier, G, Despres, P.C, Dube, A.K, Landry, C.R, Shi, R. | Deposit date: | 2024-01-11 | Release date: | 2024-08-21 | Last modified: | 2024-09-04 | Method: | X-RAY DIFFRACTION (2.67 Å) | Cite: | Compensatory mutations potentiate constructive neutral evolution by gene duplication. Science, 385, 2024
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8VLK
| Crystal structure of the yeast cytosine deaminase containing both open and closed active sites | Descriptor: | 1,2-ETHANEDIOL, Cytosine deaminase, SULFATE ION, ... | Authors: | Picard, M.-E, Grenier, J, Despres, P.C, Dube, A.K, Landry, C.R, Shi, R. | Deposit date: | 2024-01-11 | Release date: | 2024-08-21 | Last modified: | 2024-09-04 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | Compensatory mutations potentiate constructive neutral evolution by gene duplication. Science, 385, 2024
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7DXP
| Influenza H5N1 nucleoprotein in complex with nucleotides | Descriptor: | 1,2-ETHANEDIOL, Nucleoprotein, RNA (5'-R(P*(OMU)P*(OMU)P*(OMU)P*(OMU))-3') | Authors: | Tang, Y.S, Xu, S, Chen, Y.W, Wang, J.H, Shaw, P.C. | Deposit date: | 2021-01-19 | Release date: | 2021-04-14 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structures of influenza nucleoprotein complexed with nucleic acid provide insights into the mechanism of RNA interaction. Nucleic Acids Res., 49, 2021
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8VLJ
| Crystal structure of the cacodylate-bound yeast cytosine deaminase (closed form) | Descriptor: | 1,2-ETHANEDIOL, CACODYLATE ION, Cytosine deaminase, ... | Authors: | Picard, M.-E, Grenier, J, Despres, P.C, Dube, A.K, Landry, C.R, Shi, R. | Deposit date: | 2024-01-11 | Release date: | 2024-08-21 | Last modified: | 2024-09-04 | Method: | X-RAY DIFFRACTION (1.39 Å) | Cite: | Compensatory mutations potentiate constructive neutral evolution by gene duplication. Science, 385, 2024
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8VLL
| Crystal structure of the yeast cytosine deaminase (yCD) M100W mutant | Descriptor: | 1,2-ETHANEDIOL, Cytosine deaminase, PHOSPHATE ION, ... | Authors: | Picard, M.-E, Grenier, J, Despres, P.C, Dube, A.K, Landry, C.R, Shi, R. | Deposit date: | 2024-01-11 | Release date: | 2024-08-21 | Last modified: | 2024-09-18 | Method: | X-RAY DIFFRACTION (1.67 Å) | Cite: | Compensatory mutations potentiate constructive neutral evolution by gene duplication. Science, 385, 2024
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7CIV
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8WME
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8WMB
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7C8S
| Crystal structure of DUSP22 mutant_N128A | Descriptor: | Dual specificity protein phosphatase 22, SULFATE ION | Authors: | Lai, C.H, Lyu, P.C. | Deposit date: | 2020-06-03 | Release date: | 2020-10-28 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.31 Å) | Cite: | Structural Insights into the Active Site Formation of DUSP22 in N-loop-containing Protein Tyrosine Phosphatases. Int J Mol Sci, 21, 2020
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7FV2
| PanDDA analysis group deposition -- PHIP in complex with Z445899798 | Descriptor: | N-(2-methoxyethyl)-4-(thiophene-2-carbonyl)piperazine-1-carboxamide, PH-interacting protein | Authors: | Grosjean, H, Tomlinson, C, Bradshaw, W.J, Koekemoer, L, Krojer, T, Fearon, D, Biggin, P.C, von Delft, F. | Deposit date: | 2023-03-09 | Release date: | 2023-03-29 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | PanDDA analysis group deposition To Be Published
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7FV1
| PanDDA analysis group deposition -- PHIP in complex with Z4912742920 | Descriptor: | PH-interacting protein, tert-butyl [3-({[4-(furan-2-carbonyl)piperazine-1-carbonyl]amino}methyl)phenyl]carbamate | Authors: | Grosjean, H, Tomlinson, C, Bradshaw, W.J, Koekemoer, L, Krojer, T, Fearon, D, Biggin, P.C, von Delft, F. | Deposit date: | 2023-03-09 | Release date: | 2023-03-29 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.19 Å) | Cite: | PanDDA analysis group deposition To Be Published
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7FVI
| PanDDA analysis group deposition -- PHIP in complex with Z183306756 | Descriptor: | N-[(2H-1,3-benzodioxol-5-yl)methyl]-4-(furan-2-carbonyl)piperazine-1-carboxamide, PH-interacting protein | Authors: | Grosjean, H, Tomlinson, C, Bradshaw, W.J, Koekemoer, L, Krojer, T, Fearon, D, Biggin, P.C, von Delft, F. | Deposit date: | 2023-03-09 | Release date: | 2023-03-29 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.18 Å) | Cite: | PanDDA analysis group deposition To Be Published
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7FVG
| PanDDA analysis group deposition -- PHIP in complex with Z992453336 | Descriptor: | N-(4-methoxyphenyl)-4-(5-methylfuran-2-carbonyl)piperazine-1-carboxamide, PH-interacting protein | Authors: | Grosjean, H, Tomlinson, C, Bradshaw, W.J, Koekemoer, L, Krojer, T, Fearon, D, Biggin, P.C, von Delft, F. | Deposit date: | 2023-03-09 | Release date: | 2023-03-29 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | PanDDA analysis group deposition To Be Published
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7FVL
| PanDDA analysis group deposition -- PHIP in complex with Z4140355932 | Descriptor: | N-{[(2S)-5,5-dimethyl-1,4-dioxan-2-yl]methyl}-4-(3-hydroxybenzoyl)piperazine-1-carboxamide, PH-interacting protein | Authors: | Grosjean, H, Tomlinson, C, Bradshaw, W.J, Koekemoer, L, Krojer, T, Fearon, D, Biggin, P.C, von Delft, F. | Deposit date: | 2023-03-09 | Release date: | 2023-03-29 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | PanDDA analysis group deposition To Be Published
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7FVJ
| PanDDA analysis group deposition -- PHIP in complex with Z4913873236 | Descriptor: | (2S)-4-(furan-2-carbonyl)-2-methyl-N-(2,2,2-trifluoroethyl)piperazine-1-carboxamide, PH-interacting protein | Authors: | Grosjean, H, Tomlinson, C, Bradshaw, W.J, Koekemoer, L, Krojer, T, Fearon, D, Biggin, P.C, von Delft, F. | Deposit date: | 2023-03-09 | Release date: | 2023-03-29 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.19 Å) | Cite: | PanDDA analysis group deposition To Be Published
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7FVA
| PanDDA analysis group deposition -- PHIP in complex with Z4913872963 | Descriptor: | (2S)-N-(cyclopropylmethyl)-4-(furan-2-carbonyl)-2-methylpiperazine-1-carboxamide, PH-interacting protein | Authors: | Grosjean, H, Tomlinson, C, Bradshaw, W.J, Koekemoer, L, Krojer, T, Fearon, D, Biggin, P.C, von Delft, F. | Deposit date: | 2023-03-09 | Release date: | 2023-03-29 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.19 Å) | Cite: | PanDDA analysis group deposition To Be Published
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7FV9
| PanDDA analysis group deposition -- PHIP in complex with Z1004253138 | Descriptor: | 4-(5-methylfuran-2-carbonyl)-N-[(thiophen-2-yl)methyl]piperazine-1-carboxamide, PH-interacting protein | Authors: | Grosjean, H, Tomlinson, C, Bradshaw, W.J, Koekemoer, L, Krojer, T, Fearon, D, Biggin, P.C, von Delft, F. | Deposit date: | 2023-03-09 | Release date: | 2023-03-29 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.17 Å) | Cite: | PanDDA analysis group deposition To Be Published
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7FVQ
| PanDDA analysis group deposition -- PHIP in complex with Z68576046 | Descriptor: | N-butyl-4-(thiophene-2-carbonyl)piperazine-1-carboxamide, PH-interacting protein | Authors: | Grosjean, H, Tomlinson, C, Bradshaw, W.J, Koekemoer, L, Krojer, T, Fearon, D, Biggin, P.C, von Delft, F. | Deposit date: | 2023-03-09 | Release date: | 2023-03-29 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | PanDDA analysis group deposition To Be Published
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7FVM
| PanDDA analysis group deposition -- PHIP in complex with Z1590917771 | Descriptor: | 4-(furan-2-carbonyl)-N-(1,2-oxazol-3-yl)piperazine-1-carboxamide, PH-interacting protein | Authors: | Grosjean, H, Tomlinson, C, Bradshaw, W.J, Koekemoer, L, Krojer, T, Fearon, D, Biggin, P.C, von Delft, F. | Deposit date: | 2023-03-09 | Release date: | 2023-03-29 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.26 Å) | Cite: | PanDDA analysis group deposition To Be Published
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