6F9P
| Crystal structure of the Fe(II)/alpha-ketoglutarate dependent dioxygenase KDO5 with Re(II) | 分子名称: | CHLORIDE ION, GLYCEROL, L-lysine 4-hydroxylase, ... | 著者 | Isabet, T, Stura, E, Legrand, P, Zaparucha, A, Bastard, K. | 登録日 | 2017-12-15 | 公開日 | 2018-11-14 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural Studies based on two Lysine Dioxygenases with Distinct Regioselectivity Brings Insights Into Enzyme Specificity within the Clavaminate Synthase-Like Family. Sci Rep, 8, 2018
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3JVO
| Crystal structure of bacteriophage HK97 gp6 | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, Gp6 | 著者 | Lam, R, Tuite, A, Battaile, K.P, Edwards, A.M, Maxwell, K.L, Chirgadze, N.Y. | 登録日 | 2009-09-17 | 公開日 | 2009-11-24 | 最終更新日 | 2017-11-01 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | The crystal structure of bacteriophage HK97 gp6: defining a large family of head-tail connector proteins. J.Mol.Biol., 395, 2010
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1PIL
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8JJV
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6SIQ
| Fragment AZ-012 binding at the p53pT387/14-3-3 sigma interface | 分子名称: | 14-3-3 protein sigma, 4-chloranyl-7-propan-2-yloxy-1-benzothiophene-2-carboximidamide, CHLORIDE ION, ... | 著者 | Leysen, S, Wolter, M, Guillory, X, Genet, S, Somsen, B, Patel, J, Castaldi, P, Ottmann, C. | 登録日 | 2019-08-10 | 公開日 | 2020-06-17 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.60121 Å) | 主引用文献 | Fragment-based Differential Targeting of PPI Stabilizer Interfaces. J.Med.Chem., 63, 2020
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2YM4
| Crystal structure of checkpoint kinase 1 (Chk1) in complex with inhibitors | 分子名称: | 1,2-ETHANEDIOL, SERINE/THREONINE-PROTEIN KINASE CHK1, ethyl 4-[(2R)-2-(aminomethyl)morpholin-4-yl]-3-(3-cyanophenyl)-1H-pyrazolo[3,4-b]pyridine-5-carboxylate | 著者 | Reader, J.C, Matthews, T.P, Klair, S, Cheung, K.M.J, Scanlon, J, Proisy, N, Addison, G, Ellard, J, Piton, N, Taylor, S, Cherry, M, Fisher, M, Boxall, K, Burns, S, Walton, M.I, Westwood, I.M, Hayes, A, Eve, P, Valenti, M, Brandon, A.H, Box, G, vanMontfort, R.L.M, Williams, D.H, Aherne, G.W, Raynaud, F.I, Eccles, S.A, Garrett, M.D, Collins, I. | 登録日 | 2011-06-06 | 公開日 | 2012-01-11 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Structure-Guided Evolution of Potent and Selective Chk1 Inhibitors Through Scaffold Morphing. J.Med.Chem., 54, 2011
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7TBK
| Composite structure of the dilated human nuclear pore complex (NPC) symmetric core generated with a 37A in situ cryo-ET map of CD4+ T cell NPC | 分子名称: | NUP107 CTD, NUP107 NTD, NUP133, ... | 著者 | Petrovic, S, Samanta, D, Perriches, T, Bley, C.J, Thierbach, K, Brown, B, Nie, S, Mobbs, G.W, Stevens, T.A, Liu, X, Tomaleri, G.P, Schaus, L, Hoelz, A. | 登録日 | 2021-12-22 | 公開日 | 2022-06-15 | 最終更新日 | 2022-06-22 | 実験手法 | ELECTRON MICROSCOPY (37 Å) | 主引用文献 | Architecture of the linker-scaffold in the nuclear pore. Science, 376, 2022
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6SA4
| SALSA / DMBT1 / GP340 SRCR domain 1 | 分子名称: | CHLORIDE ION, Deleted in malignant brain tumors 1 protein, GLYCEROL, ... | 著者 | Reichhardt, M.P, Lea, S.M, Johnson, S. | 登録日 | 2019-07-16 | 公開日 | 2020-03-18 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | 主引用文献 | Structures of SALSA/DMBT1 SRCR domains reveal the conserved ligand-binding mechanism of the ancient SRCR fold. Life Sci Alliance, 3, 2020
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1K9W
| HIV-1(MAL) RNA Dimerization Initiation Site | 分子名称: | HIV-1 DIS(Mal)UU RNA, MAGNESIUM ION | 著者 | Ennifar, E, Walter, P, Ehresmann, B, Ehresmann, C, Dumas, P. | 登録日 | 2001-10-31 | 公開日 | 2001-11-30 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Crystal structures of coaxially stacked kissing complexes of the HIV-1 RNA dimerization initiation site. Nat.Struct.Biol., 8, 2001
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7TBJ
| Composite structure of the human nuclear pore complex (NPC) symmetric core generated with a 12A cryo-ET map of the purified HeLa cell NPC | 分子名称: | NUP107 CTD, NUP107 NTD, NUP133, ... | 著者 | Petrovic, S, Samanta, D, Perriches, T, Bley, C.J, Thierbach, K, Brown, B, Nie, S, Mobbs, G.W, Stevens, T.A, Liu, X, Tomaleri, G.P, Schaus, L, Hoelz, A. | 登録日 | 2021-12-22 | 公開日 | 2022-06-22 | 最終更新日 | 2022-06-29 | 実験手法 | ELECTRON MICROSCOPY (23 Å) | 主引用文献 | Architecture of the linker-scaffold in the nuclear pore. Science, 376, 2022
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1U07
| Crystal Structure of the 92-residue C-term. part of TonB with significant structural changes compared to shorter fragments | 分子名称: | TonB protein | 著者 | Koedding, J, Killig, F, Polzer, P, Howard, S.P, Diederichs, K, Welte, W. | 登録日 | 2004-07-13 | 公開日 | 2004-11-30 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.13 Å) | 主引用文献 | Crystal structure of a 92-residue c-terminal fragment of TonB from Escherichia coli reveals significant conformational changes compared to structures of smaller TonB fragments J.Biol.Chem., 280, 2005
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6F1C
| C1rC1s complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Complement C1r subcomponent, ... | 著者 | Almitairi, J.O.M, Venkatraman Girija, U, Furze, C.M, Simpson-Gray, X, Badakshi, F, Marshall, J.E, Mitchell, D.A, Moody, P.C.E, Wallis, R. | 登録日 | 2017-11-21 | 公開日 | 2018-01-17 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (4.2 Å) | 主引用文献 | Structure of the C1r-C1s interaction of the C1 complex of complement activation. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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7ASX
| Fixed-target serial femtosecond crystallography using in cellulo grown Neurospora crassa HEX-1 microcrystals. (Chip 1) | 分子名称: | eIF-5a domain-containing protein | 著者 | Lahey-Rudolph, J.M, Schoenherr, R, Barthelmess, M, Fischer, P, Seuring, C, Wagner, A, Meents, A, Redecke, L. | 登録日 | 2020-10-28 | 公開日 | 2021-06-23 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Fixed-target serial femtosecond crystallography using in cellulo grown microcrystals. Iucrj, 8, 2021
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7ASI
| Fixed-target serial femtosecond crystallography using in cellulo grown Neurospora crassa HEX-1 microcrystals. (Chips 1+2) | 分子名称: | eIF-5a domain-containing protein | 著者 | Lahey-Rudolph, J.M, Schoenherr, R, Barthelmess, M, Fischer, P, Seuring, C, Wagner, A, Meents, A, Redecke, L. | 登録日 | 2020-10-27 | 公開日 | 2021-06-23 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.704 Å) | 主引用文献 | Fixed-target serial femtosecond crystallography using in cellulo grown microcrystals. Iucrj, 8, 2021
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2WEF
| Human 3'(2'), 5'-bisphosphate nucleotidase 1 (BPNT1) in complex with AMP, PO4 and Magnesium | 分子名称: | 3'(2'), 5'-BISPHOSPHATE NUCLEOTIDASE 1, ADENOSINE MONOPHOSPHATE, ... | 著者 | Moche, M, Schutz, P, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Dahlgren, L.G, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Karlberg, T, Kotenyova, T, Nilsson, M.E, Nyman, T, Persson, C, Sagemark, J, Schueler, H, Siponen, M.I, Thorsell, A.G, Tresaugues, L, Van Der Berg, S, Weigelt, J, Welin, M, Wisniewska, M, Nordlund, P, Structural Genomics Consortium (SGC) | 登録日 | 2009-03-30 | 公開日 | 2009-04-14 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Human 3'(2'), 5'-Bisphosphate Nucleotidase 1 (Bpnt1) in Complex with AMP, Po4 and Magnesium To be Published
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3K35
| Crystal Structure of Human SIRT6 | 分子名称: | ADENOSINE-5-DIPHOSPHORIBOSE, NAD-dependent deacetylase sirtuin-6, SULFATE ION, ... | 著者 | Pan, P.W, Dong, A, Qiu, W, Loppnau, P, Wang, J, Ravichandran, M, Bochkarev, A, Bountra, C, Weigelt, J, Arrowsmith, C.H, Min, J, Edwards, A.M, Structural Genomics Consortium (SGC) | 登録日 | 2009-10-01 | 公開日 | 2009-12-08 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure and biochemical functions of SIRT6. J.Biol.Chem., 286, 2011
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2W17
| CDK2 in complex with the imidazole pyrimidine amide, compound (S)-8b | 分子名称: | ACETATE ION, CELL DIVISION PROTEIN KINASE 2, N-(4-{[(3S)-3-(dimethylamino)pyrrolidin-1-yl]carbonyl}phenyl)-5-fluoro-4-[2-methyl-1-(1-methylethyl)-1H-imidazol-5-yl]pyrimidin-2-amine | 著者 | Jones, C.D, Andrews, D.M, Barker, A.J, Blades, K, Daunt, P, East, S, Geh, C, Graham, M.A, Johnson, K.M, Loddick, S.A, McFarland, H.M, McGregor, A, Moss, L, Rudge, D.A, Simpson, P.B, Swain, M.L, Tam, K.Y, Tucker, J.A, Walker, M, Brassington, C, Haye, H, McCall, E. | 登録日 | 2008-10-15 | 公開日 | 2008-11-04 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | The Discovery of Azd5597, a Potent Imidazole Pyrimidine Amide Cdk Inhibitor Suitable for Intravenous Dosing. Bioorg.Med.Chem.Lett., 18, 2008
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3O4Q
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5CH3
| E3 alpha-esterase-7 carboxylesterase | 分子名称: | Carboxylic ester hydrolase | 著者 | Correy, G, Mabbitt, P, Jackson, C.J. | 登録日 | 2015-07-10 | 公開日 | 2016-06-15 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | 主引用文献 | Mapping the Accessible Conformational Landscape of an Insect Carboxylesterase Using Conformational Ensemble Analysis and Kinetic Crystallography. Structure, 24, 2016
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1Y9F
| Crystal structure of the A-DNA GCGTAT*CGC with a 2'-O-allyl Thymidine (T*) | 分子名称: | 5'-D(*GP*CP*GP*TP*AP*(2AT)P*AP*CP*GP*C)-3') | 著者 | Egli, M, Minasov, G, Tereshko, V, Pallan, P.S, Teplova, M, Inamati, G.B, Lesnik, E.A, Owens, S.R, Ross, B.S, Prakash, T.P, Manoharan, M. | 登録日 | 2004-12-15 | 公開日 | 2005-06-28 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Probing the Influence of Stereoelectronic Effects on the Biophysical Properties of Oligonucleotides: Comprehensive Analysis of the RNA Affinity, Nuclease Resistance, and Crystal Structure of Ten 2'-O-Ribonucleic Acid Modifications. Biochemistry, 44, 2005
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6SE4
| Crystal Structure of the first bromodomain of human BRD4 in complex with (+)-JD1, an Organometallic BET Bromodomain Inhibitor | 分子名称: | (+)-JD1, 1,2-ETHANEDIOL, Bromodomain-containing protein 4, ... | 著者 | Krojer, T, Hassell-Hart, S, Picaud, S, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Filippakopoulos, P, Spencer, J, von Delft, F, Structural Genomics Consortium (SGC) | 登録日 | 2019-07-29 | 公開日 | 2019-08-14 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.38 Å) | 主引用文献 | Crystal Structure of the first bromodomain of human BRD4 in complex with (+)-JD1, an Organometallic BET Bromodomain Inhibitor To Be Published
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6F45
| Crystal structure of the gp37-gp38 adhesin tip complex of the bacteriophage S16 long tail fiber | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, IMIDAZOLE, ... | 著者 | Dunne, M, Leiman, P, Klumpp, J, Loessner, M.J. | 登録日 | 2017-11-29 | 公開日 | 2018-08-01 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.70355821 Å) | 主引用文献 | Salmonella Phage S16 Tail Fiber Adhesin Features a Rare Polyglycine Rich Domain for Host Recognition. Structure, 26, 2018
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6PHD
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7ARR
| The de novo designed hybrid alpha/beta-miniprotein | 分子名称: | CHLORIDE ION, MAGNESIUM ION, alpha/beta-peptide, ... | 著者 | Bejger, M, Fortuna, P, Drewniak-Switalska, M, Rypniewski, W, Berlicki, L. | 登録日 | 2020-10-26 | 公開日 | 2021-07-14 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | A computationally designed beta-amino acid-containing miniprotein. Chem.Commun.(Camb.), 57, 2021
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2VXH
| The crystal structure of chlorite dismutase: a detox enzyme producing molecular oxygen | 分子名称: | CARBONATE ION, CHLORITE DISMUTASE, PROTOPORPHYRIN IX CONTAINING FE, ... | 著者 | De Geus, D.C, Thomassen, E.A.J, Hagedoorn, P.L, Pannu, N.S, Abrahams, J.P. | 登録日 | 2008-07-04 | 公開日 | 2009-03-03 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal Structure of Chlorite Dismutase, a Detoxifying Enzyme Producing Molecular Oxygen J.Mol.Biol., 387, 2009
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