4C4Z
 
 | | Crystal structure of human bifunctional epoxide hydroxylase 2 complexed with A8 | | 分子名称: | 1-ethyl-3-naphthalen-1-ylurea, BIFUNCTIONAL EPOXIDE HYDROLASE 2 | | 著者 | Pilger, J, Mazur, A, Monecke, P, Schreuder, H, Elshorst, B, Langer, T, Schiffer, A, Krimm, I, Wegstroth, M, Lee, D, Hessler, G, Wendt, K.-U, Becker, S, Griesinger, C. | | 登録日 | 2013-09-09 | | 公開日 | 2014-10-01 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | | 主引用文献 | A Combination of Spin Diffusion Methods for the Determination of Protein-Ligand Complex Structural Ensembles.
Angew.Chem.Int.Ed.Engl., 54, 2015
|
|
5OEZ
 | | Crystal structure of Leishmania major fructose-1,6-bisphosphatase in apo form. | | 分子名称: | FBP protein | | 著者 | Yuan, M, Vasquez-Valdivieso, M.G, McNae, I.W, Michels, P.A.M, Fothergill-Gilmore, L.A, Walkinshaw, M.D. | | 登録日 | 2017-07-10 | | 公開日 | 2017-09-20 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | | 主引用文献 | Structures of Leishmania Fructose-1,6-Bisphosphatase Reveal Species-Specific Differences in the Mechanism of Allosteric Inhibition.
J. Mol. Biol., 429, 2017
|
|
3EIJ
 | | Crystal structure of Pdcd4 | | 分子名称: | Programmed cell death protein 4 | | 著者 | Loh, P.G. | | 登録日 | 2008-09-16 | | 公開日 | 2009-02-17 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural basis for translational inhibition by the tumour suppressor Pdcd4
Embo J., 28, 2009
|
|
1SP2
 | |
2J5Y
 | | Crystal structure of the GA module from F.magna | | 分子名称: | PEPTOSTREPTOCOCCAL ALBUMIN-BINDING PROTEIN | | 著者 | Lejon, S, Cramer, J.F, Nordberg, P.A, Lundqvist, T, Valegard, K. | | 登録日 | 2006-09-20 | | 公開日 | 2007-06-26 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Crystal Structure of a Bacterial Albumin-Binding Domain at 1.4A Resolution.
FEBS Lett., 581, 2007
|
|
4CA9
 | | Structure of the Nucleoplasmin-like N-terminal domain of Drosophila FKBP39 | | 分子名称: | 39 KDA FK506-BINDING NUCLEAR PROTEIN | | 著者 | Artero, J, Forsyth, T, Callow, P, Watson, A.A, Zhang, W, Laue, E.D, Edlich-Muth, C, Przewloka, M. | | 登録日 | 2013-10-07 | | 公開日 | 2014-10-29 | | 最終更新日 | 2024-06-19 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The Pentameric Nucleoplasmin Fold is Present in Drosophila Fkbp39 and a Large Number of Chromatin-Related Proteins.
J.Mol.Biol., 427, 2015
|
|
4C0J
 | | Crystal structure of Drosophila Miro EF hand and cGTPase domains in the apo state (Apo-MiroS) | | 分子名称: | L-HOMOSERINE, MITOCHONDRIAL RHO GTPASE, SODIUM ION, ... | | 著者 | Klosowiak, J.L, Focia, P.J, Wawrzak, Z, Chakravarthy, S, Landahl, E.C, Freymann, D.M, Rice, S.E. | | 登録日 | 2013-08-05 | | 公開日 | 2013-10-09 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.82 Å) | | 主引用文献 | Structural Coupling of the EF Hand and C-Terminal Gtpase Domains in the Mitochondrial Protein Miro.
Embo Rep., 14, 2013
|
|
8A19
 | | Structure of a leucinostatin derivative determined by host lattice display : L1E4V1 construct | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 6-(2-methoxyethoxy)-11,15-dimethyl-8-oxa-2,11,15,19,21,23-hexazatetracyclo[15.6.1.13,7.020,24]pentacosa-1(23),3(25),4,6,17,20(24),21-heptaen-10-one, ... | | 著者 | Mittl, P.R.E. | | 登録日 | 2022-06-01 | | 公開日 | 2022-12-07 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.358 Å) | | 主引用文献 | Structure of a hydrophobic leucinostatin derivative determined by host lattice display.
Acta Crystallogr D Struct Biol, 78, 2022
|
|
4BPF
 | |
3E64
 | | Fragment based discovery of JAK-2 inhibitors | | 分子名称: | 4-(3-amino-1H-indazol-5-yl)-N-tert-butylbenzenesulfonamide, Tyrosine-protein kinase JAK2 | | 著者 | Antonysamy, S, Fang, W, Hirst, G, Park, F, Russell, M, Smyth, L, Sprengeler, P, Stappenbeck, F, Steensma, R, Thompson, D.A, Wilson, M, Wong, M, Zhang, A, Zhang, F. | | 登録日 | 2008-08-14 | | 公開日 | 2008-10-14 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Fragment-based discovery of JAK-2 inhibitors.
Bioorg.Med.Chem.Lett., 19, 2009
|
|
4C0K
 | | Crystal structure of Drosophila Miro EF hand and cGTPase domains bound to one calcium ion (Ca-MiroS) | | 分子名称: | CALCIUM ION, L-HOMOSERINE, MITOCHONDRIAL RHO GTPASE, ... | | 著者 | Klosowiak, J.L, Focia, P.J, Wawrzak, Z, Chakravarthy, S, Landahl, E.C, Freymann, D.M, Rice, S.E. | | 登録日 | 2013-08-05 | | 公開日 | 2013-10-09 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.801 Å) | | 主引用文献 | Structural Coupling of the EF Hand and C-Terminal Gtpase Domains in the Mitochondrial Protein Miro.
Embo Rep., 14, 2013
|
|
5OHO
 | |
4C0L
 | | Crystal structure of Drosophila Miro EF hand and cGTPase domains bound to one magnesium ion and Mg:GDP (MgGDP-MiroS) | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, L-HOMOSERINE, MAGNESIUM ION, ... | | 著者 | Klosowiak, J.L, Focia, P.J, Wawrzak, Z, Chakravarthy, S, Landahl, E.C, Freymann, D.M, Rice, S.E. | | 登録日 | 2013-08-05 | | 公開日 | 2013-10-09 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural Coupling of the EF Hand and C-Terminal Gtpase Domains in the Mitochondrial Protein Miro.
Embo Rep., 14, 2013
|
|
4XBU
 | | In vitro Crystal Structure of PAK4 in complex with Inka peptide | | 分子名称: | Protein FAM212A, Serine/threonine-protein kinase PAK 4 | | 著者 | Baskaran, Y, Ang, K.C, Anekal, P.V, Chan, W.L, Grimes, J.M, Manser, E, Robinson, R.C. | | 登録日 | 2014-12-17 | | 公開日 | 2015-12-02 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | | 主引用文献 | An in cellulo-derived structure of PAK4 in complex with its inhibitor Inka1
Nat Commun, 6, 2015
|
|
2IZX
 | | Molecular Basis of AKAP Specificity for PKA Regulatory Subunits | | 分子名称: | AKAP-IS, CAMP-DEPENDENT PROTEIN KINASE TYPE II-ALPHA REGULATORY SUBUNIT, DITHIANE DIOL | | 著者 | Gold, M.G, Lygren, B, Dokurno, P, Hoshi, N, McConnachie, G, Tasken, K, Carlson, C.R, Scott, J.D, Barford, D. | | 登録日 | 2006-07-27 | | 公開日 | 2006-11-08 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Molecular Basis of Akap Specificity for Pka Regulatory Subunits.
Mol.Cell, 24, 2006
|
|
1SP1
 | |
8EFN
 | | Structure of Sp-STING3 from Stylophora pistillata coral in complex with 3',3'-cGAMP | | 分子名称: | 1,2-ETHANEDIOL, 2-amino-9-[(2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-9-(6-amino-9H-purin-9-yl)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecin-2-yl]-1,9-dihydro-6H-purin-6-one, Stimulator of interferon genes protein | | 著者 | Li, Y, Slavik, K.M, Morehouse, B.R, Mears, K, Kranzusch, P.J. | | 登録日 | 2022-09-08 | | 公開日 | 2023-07-05 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | | 主引用文献 | cGLRs are a diverse family of pattern recognition receptors in innate immunity.
Cell, 186, 2023
|
|
7PNL
 | | Complex between monomolecular human telomeric G-quadruplex and a sulfonamide derivative of the natural alkaloid Berberine | | 分子名称: | 4-[[1-[3-[(17-methoxy-5,7-dioxa-13-azoniapentacyclo[11.8.0.0^{2,10}.0^{4,8}.0^{15,20}]henicosa-1(21),2(10),3,8,13,15,17,19-octaen-16-yl)oxy]propyl]triazol-4-yl]methoxy]benzenesulfonamide, G-guadruplex DNA (23-mer), POTASSIUM ION | | 著者 | Bazzicalupi, C, Gratteri, P, Petreni, A, Nocentini, A. | | 登録日 | 2021-09-07 | | 公開日 | 2022-09-21 | | 最終更新日 | 2024-07-24 | | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | | 主引用文献 | Development of a multi-targeted chemotherapeutic approach based on G-quadruplex stabilisation and carbonic anhydrase inhibition.
J Enzyme Inhib Med Chem, 39, 2024
|
|
7ZZY
 | |
1SAY
 | | L-ALANINE DEHYDROGENASE COMPLEXED WITH PYRUVATE | | 分子名称: | L-ALANINE DEHYDROGENASE, PYRUVIC ACID | | 著者 | Baker, P.J, Sawa, Y, Shibata, H, Sedelnikova, S.E, Rice, D.W. | | 登録日 | 1998-06-05 | | 公開日 | 1999-06-08 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Analysis of the structure and substrate binding of Phormidium lapideum alanine dehydrogenase.
Nat.Struct.Biol., 5, 1998
|
|
7PPX
 | | ATAD2 in complex with FragLite3 | | 分子名称: | 1,2-ETHANEDIOL, 4-bromanyl-1,2-oxazole, ATPase family AAA domain-containing protein 2, ... | | 著者 | Turberville, S, Martin, M.P, Hope, I, Wood, D.J, Ng, Y.M, Heath, R, Endicott, J.A, Noble, M.E.M. | | 登録日 | 2021-09-15 | | 公開日 | 2022-09-21 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | Mapping Ligand Interactions of Bromodomains BRD4 and ATAD2 with FragLites and PepLites─Halogenated Probes of Druglike and Peptide-like Molecular Interactions.
J.Med.Chem., 65, 2022
|
|
8EFM
 | | Structure of coral STING receptor from Stylophora pistillata in complex with 2',3'-cGAMP | | 分子名称: | SULFATE ION, Stimulator of interferon genes protein, cGAMP | | 著者 | Li, Y, Slavik, K.M, Morehouse, B.R, Mears, K, Kranzusch, P.J. | | 登録日 | 2022-09-08 | | 公開日 | 2023-07-05 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | | 主引用文献 | cGLRs are a diverse family of pattern recognition receptors in innate immunity.
Cell, 186, 2023
|
|
4BRJ
 | | Superoxide reductase (Neelaredoxin) from Ignicoccus hospitalis T24K | | 分子名称: | DESULFOFERRODOXIN, FERROUS IRON-BINDING REGION, FE (III) ION | | 著者 | Romao, C.V, Matias, P.M, Pinho, F.G, Sousa, C.M, Barradas, A.R, Pinto, A.F, Teixeira, M, Bandeiras, T.M. | | 登録日 | 2013-06-04 | | 公開日 | 2014-06-11 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structure of a Natural Sor Mutant
To be Published
|
|
7ZR1
 | | Chaetomium thermophilum Mre11-Rad50-Nbs1 complex bound to ATPyS (composite structure) | | 分子名称: | DH domain-containing protein, Double-strand break repair protein, FHA domain-containing protein, ... | | 著者 | Bartho, J.D, Rotheneder, M, Stakyte, K, Lammens, K, Hopfner, K.P. | | 登録日 | 2022-05-03 | | 公開日 | 2023-01-11 | | 最終更新日 | 2023-12-13 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Cryo-EM structure of the Mre11-Rad50-Nbs1 complex reveals the molecular mechanism of scaffolding functions.
Mol.Cell, 83, 2023
|
|
2J9R
 | | Thymidine kinase from B. anthracis in complex with dT. | | 分子名称: | PHOSPHATE ION, THYMIDINE, THYMIDINE KINASE, ... | | 著者 | Kosinska, U, Carnrot, C, Sandrini, M.P.B, Clausen, A.R, Wang, L, Piskur, J, Eriksson, S, Eklund, H. | | 登録日 | 2006-11-15 | | 公開日 | 2007-01-23 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural Studies of Thymidine Kinases from Bacillus Anthracis and Bacillus Cereus Provide Insights Into Quaternary Structure and Conformational Changes Upon Substrate Binding
FEBS J., 274, 2007
|
|
