8I3Q
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![BU of 8i3q by Molmil](/molmil-images/mine/8i3q) | |
6L00
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6M6U
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![BU of 6m6u by Molmil](/molmil-images/mine/6m6u) | Crystal structure the toxin-antitoxin MntA-HpeT mutant-D39ED41E | Descriptor: | Toxin-antitoxin system antitoxin MntA family, Toxin-antitoxin system toxin HepN family | Authors: | Ouyang, S.Y, Zhen, X.K. | Deposit date: | 2020-03-16 | Release date: | 2020-09-30 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.349 Å) | Cite: | Novel polyadenylylation-dependent neutralization mechanism of the HEPN/MNT toxin/antitoxin system. Nucleic Acids Res., 48, 2020
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6M6W
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![BU of 6m6w by Molmil](/molmil-images/mine/6m6w) | Crystal structure the toxin-antitoxin MntA-HpeT mutant-Y104A | Descriptor: | Toxin-antitoxin system antidote Mnt family, Toxin-antitoxin system toxin HepN family | Authors: | Ouyang, S.Y, Zhen, X.K. | Deposit date: | 2020-03-16 | Release date: | 2020-09-30 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.611 Å) | Cite: | Novel polyadenylylation-dependent neutralization mechanism of the HEPN/MNT toxin/antitoxin system. Nucleic Acids Res., 48, 2020
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6M6V
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![BU of 6m6v by Molmil](/molmil-images/mine/6m6v) | Crystal structure the toxin-antitoxin MntA-HepT | Descriptor: | RNA (5'-R(P*AP*AP*A)-3'), Toxin-antitoxin system antidote Mnt family, Toxin-antitoxin system toxin HepN family | Authors: | Ouyang, S.Y, Zhen, X.K. | Deposit date: | 2020-03-16 | Release date: | 2020-09-30 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.08 Å) | Cite: | Novel polyadenylylation-dependent neutralization mechanism of the HEPN/MNT toxin/antitoxin system. Nucleic Acids Res., 48, 2020
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7BU0
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7BXO
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![BU of 7bxo by Molmil](/molmil-images/mine/7bxo) | Crystal structure of the toxin-antitoxin with AMP-PNP | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Toxin-antitoxin system antidote Mnt family, ... | Authors: | Ouyang, S.Y, Zhen, X.K. | Deposit date: | 2020-04-20 | Release date: | 2020-09-30 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.77 Å) | Cite: | Novel polyadenylylation-dependent neutralization mechanism of the HEPN/MNT toxin/antitoxin system. Nucleic Acids Res., 48, 2020
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7CNB
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7WCF
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![BU of 7wcf by Molmil](/molmil-images/mine/7wcf) | Crystal structure of the kinase with AMP-PNP | Descriptor: | HipA_C domain-containing protein, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER | Authors: | Ouyang, S.Y, Zhen, X. | Deposit date: | 2021-12-20 | Release date: | 2022-06-29 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.3636 Å) | Cite: | Molecular mechanism of toxin neutralization in the HipBST toxin-antitoxin system of Legionella pneumophila. Nat Commun, 13, 2022
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7XVG
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![BU of 7xvg by Molmil](/molmil-images/mine/7xvg) | Cryo-EM structure of binary complex of plant NLR Sr35 and effector AvrSr35 | Descriptor: | AvrSr35, Sr35 | Authors: | Ouyang, S.Y, Zhao, Y.B, Li, Z.K, Liu, M.X. | Deposit date: | 2022-05-23 | Release date: | 2022-09-28 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Pathogen effector AvrSr35 triggers Sr35 resistosome assembly via a direct recognition mechanism. Sci Adv, 8, 2022
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7XX2
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![BU of 7xx2 by Molmil](/molmil-images/mine/7xx2) | Cryo-EM structure of Sr35 resistosome induced by AvrSr35 R381A | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, AvrSr35, CNL9 | Authors: | Ouyang, S.Y, Zhao, Y.B, Li, Z.K, Liu, M.X. | Deposit date: | 2022-05-28 | Release date: | 2022-11-02 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Pathogen effector AvrSr35 triggers Sr35 resistosome assembly via a direct recognition mechanism. Sci Adv, 8, 2022
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7XE0
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![BU of 7xe0 by Molmil](/molmil-images/mine/7xe0) | Cryo-EM structure of plant NLR Sr35 resistosome | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, AvrSr35, Sr35 | Authors: | Ouyang, S.Y, Zhao, Y.B, Li, Z.K, Liu, M.X. | Deposit date: | 2022-03-29 | Release date: | 2022-09-28 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (3.33 Å) | Cite: | Pathogen effector AvrSr35 triggers Sr35 resistosome assembly via a direct recognition mechanism. Sci Adv, 8, 2022
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7XDS
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6IM4
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![BU of 6im4 by Molmil](/molmil-images/mine/6im4) | |
6JKY
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6IST
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![BU of 6ist by Molmil](/molmil-images/mine/6ist) | Crystal structure of a wild type endolysin LysIME-EF1 | Descriptor: | CALCIUM ION, Lysin | Authors: | Ouyang, S.Y. | Deposit date: | 2018-11-19 | Release date: | 2019-11-20 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structural and functional insights into a novel two-component endolysin encoded by a single gene in Enterococcus faecalis phage. Plos Pathog., 16, 2020
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6K4L
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6K4R
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6K4K
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![BU of 6k4k by Molmil](/molmil-images/mine/6k4k) | |
8I16
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![BU of 8i16 by Molmil](/molmil-images/mine/8i16) | Crystal structure of the selenomethionine (SeMet)-derived Cas12g (D513A) mutant | Descriptor: | Cas12g, ZINC ION | Authors: | Zhang, B, Chen, J, Ye, Y.M, OuYang, S.Y. | Deposit date: | 2023-01-12 | Release date: | 2023-08-30 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.24 Å) | Cite: | Structural transitions upon guide RNA binding and their importance in Cas12g-mediated RNA cleavage. Plos Genet., 19, 2023
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8HCM
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![BU of 8hcm by Molmil](/molmil-images/mine/8hcm) | zebrafish IRF-11 DBD complex with DNA | Descriptor: | DNA (5'-D(P*GP*CP*TP*TP*TP*CP*AP*CP*TP*TP*TP*CP*TP*A)-3'), DNA (5'-D(P*TP*AP*GP*AP*AP*AP*GP*TP*GP*AP*AP*AP*GP*C)-3'), Interferon regulatory factor | Authors: | Wang, Z.X, Zhang, Y.A, Ouyang, S.Y. | Deposit date: | 2022-11-02 | Release date: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.59 Å) | Cite: | Structure of Danio rerio IRF10 and IRF11 bound DNA reveal determinants of interferon regulation To Be Published
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8HCL
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![BU of 8hcl by Molmil](/molmil-images/mine/8hcl) | zebrafish IRF-10 DBD complex with DNA | Descriptor: | DNA (5'-D(P*AP*CP*TP*TP*TP*CP*AP*CP*TP*TP*CP*A)-3'), DNA (5'-D(P*TP*GP*AP*AP*GP*TP*GP*AP*AP*AP*GP*T)-3'), Interferon regulatory factor 10 | Authors: | Wang, Z.X, Zhang, Y.A, Ouyang, S.Y. | Deposit date: | 2022-11-01 | Release date: | 2024-05-15 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Structure of Danio rerio IRF10 and IRF11 bound DNA reveal determinants of interferon regulation To Be Published
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8HCS
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![BU of 8hcs by Molmil](/molmil-images/mine/8hcs) | zebrafish IRF-11 DBD | Descriptor: | Interferon regulatory factor | Authors: | Wang, Z.X, Zhang, Y.A, Ouyang, S.Y. | Deposit date: | 2022-11-03 | Release date: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Structure of Danio rerio IRF10 and IRF11 bound DNA reveal determinants of interferon regulation To Be Published
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8HCY
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![BU of 8hcy by Molmil](/molmil-images/mine/8hcy) | Legionella glycosyltransferase | Descriptor: | Dot/Icm secretion system substrate | Authors: | Chen, T.T, Ouyang, S.Y. | Deposit date: | 2022-11-03 | Release date: | 2023-11-08 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.64 Å) | Cite: | Structural Basis for the Action Mechanism of Legionella Glycosyltransferase. Small Struct, 2023
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6AAY
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![BU of 6aay by Molmil](/molmil-images/mine/6aay) | the Cas13b binary complex | Descriptor: | Bergeyella zoohelcum Cas13b (R1177A) mutant, RNA (52-MER) | Authors: | Bo, Z, Weiwei, Y, Yangmiao, Y, Ouyang, S.Y. | Deposit date: | 2018-07-19 | Release date: | 2019-03-13 | Method: | X-RAY DIFFRACTION (2.79 Å) | Cite: | Structural insights into Cas13b-guided CRISPR RNA maturation and recognition. Cell Res., 28, 2018
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