4WXQ
 
 | | Crystal Structure of the Myocilin Olfactomedin Domain | | 分子名称: | CALCIUM ION, HEXAETHYLENE GLYCOL, Myocilin, ... | | 著者 | Orwig, S.D, Turnage, K.C, Donegan, R.K, Lieberman, R.L. | | 登録日 | 2014-11-14 | | 公開日 | 2015-04-01 | | 最終更新日 | 2017-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Structural basis for misfolding in myocilin-associated glaucoma.
Hum.Mol.Genet., 24, 2015
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3RIK
 | | The acid beta-glucosidase active site exhibits plasticity in binding 3,4,5,6-tetrahydroxyazepane-based inhibitors: implications for pharmacological chaperone design for gaucher disease | | 分子名称: | (3S,4R,5R,6S)-1-(2-hydroxyethyl)azepane-3,4,5,6-tetrol, 2-acetamido-2-deoxy-beta-D-glucopyranose, Glucosylceramidase, ... | | 著者 | Orwig, S.D, Lieberman, R.L. | | 登録日 | 2011-04-13 | | 公開日 | 2012-03-14 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | | 主引用文献 | Binding of 3,4,5,6-tetrahydroxyazepanes to the acid-beta-glucosidase active site: implications for pharmacological chaperone design for Gaucher disease
Biochemistry, 50, 2011
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3RIL
 | | The acid beta-glucosidase active site exhibits plasticity in binding 3,4,5,6-tetrahydroxyazepane-based inhibitors: implications for pharmacological chaperone design for gaucher disease | | 分子名称: | (3S,4R,5R,6S)-azepane-3,4,5,6-tetrol, 2-acetamido-2-deoxy-beta-D-glucopyranose, Glucosylceramidase, ... | | 著者 | Orwig, S.D, Lieberman, R.L. | | 登録日 | 2011-04-13 | | 公開日 | 2012-03-14 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Binding of 3,4,5,6-tetrahydroxyazepanes to the acid-beta-glucosidase active site: implications for pharmacological chaperone design for Gaucher disease
Biochemistry, 50, 2011
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