7GZX
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![BU of 7gzx by Molmil](/molmil-images/mine/7gzx) | Crystal structure of SARS-CoV-2 NSP3 Macrodomain in complex with ASAP-0011176-001 | 分子名称: | 7-[(1S)-2-methyl-1-{[(6M)-6-{5-[(methylamino)methyl]furan-3-yl}-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino}propyl]-3,4-dihydro-1lambda~6~-benzothiopyran-1,1(2H)-dione, Papain-like protease nsp3 | 著者 | Aschenbrenner, J.C, Fearon, D, Tomlinson, C.W.E, Marples, P.G, Fairhead, M, Balcomb, B.H, Chandran, A.V, Godoy, A.S, Koekemoer, L, Lithgo, R.M, Ni, X, Thompson, W, Wang, S, Wild, C, Williams, E.P, Winokan, M, Walsh, M.A, von Delft, F. | 登録日 | 2024-01-23 | 公開日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | 主引用文献 | Group deposition of SARS-CoV-2 NSP3 Macrodomain in complex with inhibitors from the ASAP AViDD centre To Be Published
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7H0H
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![BU of 7h0h by Molmil](/molmil-images/mine/7h0h) | Crystal structure of SARS-CoV-2 NSP3 Macrodomain in complex with ASAP-0011204-001 | 分子名称: | N-ethyl-4-{[(1S)-2-methyl-1-(3-methyl-4-oxo-3,4-dihydroquinazolin-6-yl)propyl]amino}-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide, Papain-like protease nsp3 | 著者 | Aschenbrenner, J.C, Fearon, D, Tomlinson, C.W.E, Marples, P.G, Fairhead, M, Balcomb, B.H, Chandran, A.V, Godoy, A.S, Koekemoer, L, Lithgo, R.M, Ni, X, Thompson, W, Wang, S, Wild, C, Williams, E.P, Winokan, M, Walsh, M.A, von Delft, F. | 登録日 | 2024-01-23 | 公開日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.31 Å) | 主引用文献 | Group deposition of SARS-CoV-2 NSP3 Macrodomain in complex with inhibitors from the ASAP AViDD centre To Be Published
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7H14
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![BU of 7h14 by Molmil](/molmil-images/mine/7h14) | Crystal structure of SARS-CoV-2 NSP3 Macrodomain in complex with ASAP-0013383-001 | 分子名称: | 7-[(1R)-2-methyl-1-{[(6M)-6-(1-methyl-6-oxo-1,6-dihydropyridin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino}propyl]-3,4-dihydro-1lambda~6~-benzothiopyran-1,1(2H)-dione, Papain-like protease nsp3 | 著者 | Aschenbrenner, J.C, Fearon, D, Tomlinson, C.W.E, Marples, P.G, Fairhead, M, Balcomb, B.H, Chandran, A.V, Godoy, A.S, Koekemoer, L, Lithgo, R.M, Ni, X, Thompson, W, Wang, S, Wild, C, Williams, E.P, Winokan, M, Walsh, M.A, von Delft, F. | 登録日 | 2024-01-23 | 公開日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | 主引用文献 | Group deposition of SARS-CoV-2 NSP3 Macrodomain in complex with inhibitors from the ASAP AViDD centre To Be Published
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7H1F
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![BU of 7h1f by Molmil](/molmil-images/mine/7h1f) | Crystal structure of SARS-CoV-2 NSP3 Macrodomain in complex with ASAP-0015381-001 | 分子名称: | N-[(1R)-1-(4-methoxyphenyl)-2-(1H-tetrazol-5-yl)ethyl]-7H-pyrrolo[2,3-d]pyrimidine-4-carboxamide, Papain-like protease nsp3 | 著者 | Aschenbrenner, J.C, Fearon, D, Tomlinson, C.W.E, Marples, P.G, Fairhead, M, Balcomb, B.H, Chandran, A.V, Godoy, A.S, Koekemoer, L, Lithgo, R.M, Ni, X, Thompson, W, Wang, S, Wild, C, Williams, E.P, Winokan, M, Walsh, M.A, von Delft, F. | 登録日 | 2024-01-23 | 公開日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | 主引用文献 | Group deposition of SARS-CoV-2 NSP3 Macrodomain in complex with inhibitors from the ASAP AViDD centre To Be Published
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2ZAM
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![BU of 2zam by Molmil](/molmil-images/mine/2zam) | Crystal structure of mouse SKD1/VPS4B apo-form | 分子名称: | Vacuolar protein sorting-associating protein 4B | 著者 | Inoue, M, Kawasaki, M, Kamikubo, H, Kataoka, M, Kato, R, Yoshimori, T, Wakatsuki, S. | 登録日 | 2007-10-08 | 公開日 | 2008-10-07 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Nucleotide-dependent conformational changes and assembly of the AAA ATPase SKD1/VPS4B Traffic, 9, 2008
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2Z1N
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![BU of 2z1n by Molmil](/molmil-images/mine/2z1n) | Crystal structure of APE0912 from Aeropyrum pernix K1 | 分子名称: | SODIUM ION, dehydrogenase | 著者 | Ichimura, T, Yamamura, A, Mimoto, F, Ohtsuka, J, Miyazono, K, Okai, M, Kamo, M, Lee, W.-C, Nagata, K, Tanokura, M. | 登録日 | 2007-05-10 | 公開日 | 2008-03-18 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | A unique catalytic triad revealed by the crystal structure of APE0912, a short-chain dehydrogenase/reductase family protein from Aeropyrum pernix K1 Proteins, 70, 2008
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2ZAO
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![BU of 2zao by Molmil](/molmil-images/mine/2zao) | Crystal structure of mouse SKD1/VPS4B ADP-form | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Vacuolar protein sorting-associating protein 4B | 著者 | Inoue, M, Kawasaki, M, Kamikubo, H, Kataoka, M, Kato, R, Yoshimori, T, Wakatsuki, S. | 登録日 | 2007-10-08 | 公開日 | 2008-10-07 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Nucleotide-dependent conformational changes and assembly of the AAA ATPase SKD1/VPS4B Traffic, 9, 2008
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2ZAN
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![BU of 2zan by Molmil](/molmil-images/mine/2zan) | Crystal structure of mouse SKD1/VPS4B ATP-form | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Vacuolar protein sorting-associating protein 4B | 著者 | Inoue, M, Kawasaki, M, Kamikubo, H, Kataoka, M, Kato, R, Yoshimori, T, Wakatsuki, S. | 登録日 | 2007-10-08 | 公開日 | 2008-10-07 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Nucleotide-dependent conformational changes and assembly of the AAA ATPase SKD1/VPS4B Traffic, 9, 2008
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3RI9
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![BU of 3ri9 by Molmil](/molmil-images/mine/3ri9) | Xylanase C from Aspergillus kawachii F131W mutant | 分子名称: | Endo-1,4-beta-xylanase 3 | 著者 | Fushinobu, S, Uno, T, Kitaoka, M, Hayashi, K, Matsuzawa, H, Wakagi, T. | 登録日 | 2011-04-13 | 公開日 | 2011-09-21 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Mutational analysis of fungal family 11 xylanases on pH optimum determination J.APPL.GLYOSCI., 58, 2011
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3RI8
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![BU of 3ri8 by Molmil](/molmil-images/mine/3ri8) | Xylanase C from Aspergillus kawachii D37N mutant | 分子名称: | Endo-1,4-beta-xylanase 3 | 著者 | Fushinobu, S, Uno, T, Kitaoka, M, Hayashi, K, Matsuzawa, H, Wakagi, T. | 登録日 | 2011-04-13 | 公開日 | 2011-10-12 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Mutational analysis of fungal family 11 xylanases on pH optimum determination J.APPL.GLYOSCI., 58, 2011
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2ZUA
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![BU of 2zua by Molmil](/molmil-images/mine/2zua) | Crystal structure of nucleoside diphosphate kinase from Haloarcula quadrata | 分子名称: | Nucleoside diphosphate kinase | 著者 | Ichimura, T, Yamamura, A, Ohtsuka, J, Miyazono, K, Okai, M, Nagata, K, Tanokura, M. | 登録日 | 2008-10-15 | 公開日 | 2009-08-25 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | 主引用文献 | Molecular mechanism of distinct salt-dependent enzyme activity of two halophilic nucleoside diphosphate kinases Biophys.J., 96, 2009
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2D1X
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![BU of 2d1x by Molmil](/molmil-images/mine/2d1x) | The crystal structure of the cortactin-SH3 domain and AMAP1-peptide complex | 分子名称: | SULFATE ION, cortactin isoform a, proline rich region from development and differentiation enhancing factor 1 | 著者 | Hashimoto, S, Hirose, M, Hashimoto, A, Morishige, M, Yamada, A, Hosaka, H, Akagi, K, Ogawa, E, Oneyama, C, Agatsuma, T, Okada, M, Kobayashi, H, Wada, H, Nakano, H, Ikegami, T, Nakagawa, A, Sabe, H. | 登録日 | 2005-09-01 | 公開日 | 2006-04-25 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Targeting AMAP1 and cortactin binding bearing an atypical src homology 3/proline interface for prevention of breast cancer invasion and metastasis. Proc.Natl.Acad.Sci.Usa, 103, 2006
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4KTR
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![BU of 4ktr by Molmil](/molmil-images/mine/4ktr) | Crystal structure of 2-O-alpha-glucosylglycerol phosphorylase in complex with isofagomine and glycerol | 分子名称: | 2-(2-(2-(2-(2-(2-ETHOXYETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHANOL, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, ... | 著者 | Touhara, K.K, Nihira, T, Kitaoka, M, Nakai, H, Fushinobu, S. | 登録日 | 2013-05-21 | 公開日 | 2014-05-21 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural basis for reversible phosphorolysis and hydrolysis reactions of 2-O-alpha-glucosylglycerol phosphorylase J.Biol.Chem., 289, 2014
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1VBH
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![BU of 1vbh by Molmil](/molmil-images/mine/1vbh) | Pyruvate Phosphate Dikinase with bound Mg-PEP from Maize | 分子名称: | MAGNESIUM ION, PHOSPHOENOLPYRUVATE, SULFATE ION, ... | 著者 | Nakanishi, T, Nakatsu, T, Matsuoka, M, Sakata, K, Kato, H, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2004-02-26 | 公開日 | 2005-03-08 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structures of pyruvate phosphate dikinase from maize revealed an alternative conformation in the swiveling-domain motion Biochemistry, 44, 2005
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4KTP
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![BU of 4ktp by Molmil](/molmil-images/mine/4ktp) | Crystal structure of 2-O-alpha-glucosylglycerol phosphorylase in complex with glucose | 分子名称: | CALCIUM ION, Glycoside hydrolase family 65 central catalytic, PENTAETHYLENE GLYCOL, ... | 著者 | Touhara, K.K, Nihira, T, Kitaoka, M, Nakai, H, Fushinobu, S. | 登録日 | 2013-05-21 | 公開日 | 2014-05-21 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural basis for reversible phosphorolysis and hydrolysis reactions of 2-O-alpha-glucosylglycerol phosphorylase J.Biol.Chem., 289, 2014
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1XWF
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![BU of 1xwf by Molmil](/molmil-images/mine/1xwf) | K185N mutated S-adenosylhomocysteine hydrolase | 分子名称: | ADENOSINE, Adenosylhomocysteinase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | 著者 | Yamada, T, Takata, Y, Komoto, J, Gomi, T, Ogawa, H, Fujioka, M, Takusagawa, F. | 登録日 | 2004-11-01 | 公開日 | 2005-09-20 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Catalytic mechanism of S-adenosylhomocysteine hydrolase: Roles of His 54, Asp130, Glu155, Lys185, and Aspl89. Int.J.Biochem.Cell Biol., 37, 2005
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1VBG
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![BU of 1vbg by Molmil](/molmil-images/mine/1vbg) | Pyruvate Phosphate Dikinase from Maize | 分子名称: | MAGNESIUM ION, SULFATE ION, pyruvate,orthophosphate dikinase | 著者 | Nakanishi, T, Nakatsu, T, Matsuoka, M, Sakata, K, Kato, H, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2004-02-26 | 公開日 | 2005-03-08 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structures of pyruvate phosphate dikinase from maize revealed an alternative conformation in the swiveling-domain motion Biochemistry, 44, 2005
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3AI3
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![BU of 3ai3 by Molmil](/molmil-images/mine/3ai3) | The crystal structure of L-Sorbose reductase from Gluconobacter frateurii complexed with NADPH and L-sorbose | 分子名称: | L-sorbose, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NADPH-sorbose reductase, ... | 著者 | Kubota, K, Nagata, K, Okai, M, Miyazono, K, Tanokura, M. | 登録日 | 2010-05-07 | 公開日 | 2011-02-09 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The Crystal Structure of l-Sorbose Reductase from Gluconobacter frateurii Complexed with NADPH and l-Sorbose J.Mol.Biol., 407, 2011
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3AI1
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![BU of 3ai1 by Molmil](/molmil-images/mine/3ai1) | The crystal structure of L-sorbose reductase from Gluconobacter frateurii complexed with NADPH and L-sorbose reveals the structure bases of its catalytic mechanism and high substrate selectivity | 分子名称: | NADPH-sorbose reductase | 著者 | Kubota, K, Nagata, K, Okai, M, Miyazono, K, Tanokura, M. | 登録日 | 2010-05-06 | 公開日 | 2011-02-09 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | 主引用文献 | The Crystal Structure of l-Sorbose Reductase from Gluconobacter frateurii Complexed with NADPH and l-Sorbose J.Mol.Biol., 407, 2011
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3AUJ
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![BU of 3auj by Molmil](/molmil-images/mine/3auj) | Structure of diol dehydratase complexed with glycerol | 分子名称: | CALCIUM ION, COBALAMIN, Diol dehydrase alpha subunit, ... | 著者 | Yamanishi, M, Kinoshita, K, Fukuoka, M, Shibata, T, Tobimatsu, T, Toraya, T. | 登録日 | 2011-02-07 | 公開日 | 2012-02-22 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Redesign of coenzyme B(12) dependent diol dehydratase to be resistant to the mechanism-based inactivation by glycerol and act on longer chain 1,2-diols Febs J., 279, 2012
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3ARN
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![BU of 3arn by Molmil](/molmil-images/mine/3arn) | Human dUTPase in complex with novel uracil derivative | 分子名称: | Deoxyuridine 5'-triphosphate nucleotidohydrolase, MAGNESIUM ION, N-{5-[(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methoxy]-2-methylpentan-2-yl}benzenesulfonamide | 著者 | Chong, K.T, Miyahara, S, Miyakoshi, H, Fukuoka, M. | 登録日 | 2010-12-03 | 公開日 | 2010-12-15 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Discovery of a novel class of potent human deoxyuridine triphosphatase inhibitors remarkably enhancing the antitumor activity of thymidylate synthase inhibitors J.Med.Chem., 55, 2012
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2CQT
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![BU of 2cqt by Molmil](/molmil-images/mine/2cqt) | Crystal Structure of Cellvibrio gilvus Cellobiose Phosphorylase Crystallized from Sodium/Potassium Phosphate | 分子名称: | Cellobiose Phosphorylase, GLYCEROL, PHOSPHATE ION, ... | 著者 | Hidaka, M, Kitaoka, M, Hayashi, K, Wakagi, T, Shoun, H, Fushinobu, S. | 登録日 | 2005-05-20 | 公開日 | 2006-05-16 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural dissection of the reaction mechanism of cellobiose phosphorylase. Biochem.J., 398, 2006
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2CQS
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![BU of 2cqs by Molmil](/molmil-images/mine/2cqs) | Crystal Structure of Cellvibrio gilvus Cellobiose Phosphorylase Crystallized from Ammonium Sulfate | 分子名称: | Cellobiose Phosphorylase, SULFATE ION, beta-D-glucopyranose | 著者 | Hidaka, M, Kitaoka, M, Hayashi, K, Wakagi, T, Shoun, H, Fushinobu, S. | 登録日 | 2005-05-20 | 公開日 | 2006-05-16 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural dissection of the reaction mechanism of cellobiose phosphorylase. Biochem.J., 398, 2006
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2CW7
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![BU of 2cw7 by Molmil](/molmil-images/mine/2cw7) | Crystal structure of intein homing endonuclease II | 分子名称: | Endonuclease PI-PkoII, SULFATE ION | 著者 | Matsumura, H, Takahashi, H, Inoue, T, Hashimoto, H, Nishioka, M, Fujiwara, S, Takagi, M, Imanaka, T, Kai, Y. | 登録日 | 2005-06-17 | 公開日 | 2006-04-18 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystal structure of intein homing endonuclease II encoded in DNA polymerase gene from hyperthermophilic archaeon Thermococcus kodakaraensis strain KOD1 Proteins, 63, 2006
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2CW8
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![BU of 2cw8 by Molmil](/molmil-images/mine/2cw8) | Crystal structure of intein homing endonuclease II | 分子名称: | Endonuclease PI-PkoII, GLYCEROL, SULFATE ION | 著者 | Matsumura, H, Takahashi, H, Inoue, T, Hashimoto, H, Nishioka, M, Fujiwara, S, Takagi, M, Imanaka, T, Kai, Y. | 登録日 | 2005-06-17 | 公開日 | 2006-04-18 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structure of intein homing endonuclease II encoded in DNA polymerase gene from hyperthermophilic archaeon Thermococcus kodakaraensis strain KOD1 Proteins, 63, 2006
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