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PDB: 15 件
8VIC
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BU of 8vic by Molmil
AP-6 bound human TMEM175
分子名称: (2P,2'P)-2,2'-(1,3-phenylene)di(pyridin-4-amine), Endosomal/lysosomal potassium channel TMEM175
著者Oh, S, Hite, R.K.
登録日2024-01-03
公開日2024-08-14
実験手法ELECTRON MICROSCOPY (3.48 Å)
主引用文献Structure of human TMEM175 in an inhibitor-bound state
To Be Published
8VIE
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BU of 8vie by Molmil
2-PPA bound human TMEM175
分子名称: 2-phenylpyridin-4-amine, Endosomal/lysosomal potassium channel TMEM175
著者Oh, S, Hite, R.K.
登録日2024-01-04
公開日2024-08-14
実験手法ELECTRON MICROSCOPY (3.52 Å)
主引用文献Structure of human TMEM175 in an inhibitor-bound state
To Be Published
6WCC
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BU of 6wcc by Molmil
Human closed state TMEM175 in CsCl
分子名称: CESIUM ION, Endosomal/lysosomal potassium channel TMEM175
著者Oh, S, Paknejad, N, Hite, R.K.
登録日2020-03-30
公開日2020-04-15
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.24 Å)
主引用文献Gating and selectivity mechanisms for the lysosomal K + channel TMEM175.
Elife, 9, 2020
6WCA
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BU of 6wca by Molmil
Human closed state TMEM175 in KCl
分子名称: Endosomal/lysosomal potassium channel TMEM175, POTASSIUM ION
著者Oh, S, Paknejad, N, Hite, R.K.
登録日2020-03-30
公開日2020-04-15
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.03 Å)
主引用文献Gating and selectivity mechanisms for the lysosomal K + channel TMEM175.
Elife, 9, 2020
6WC9
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BU of 6wc9 by Molmil
Human open state TMEM175 in KCl
分子名称: Endosomal/lysosomal potassium channel TMEM175, POTASSIUM ION
著者Oh, S, Paknejad, N, Hite, R.K.
登録日2020-03-30
公開日2020-04-15
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (2.64 Å)
主引用文献Gating and selectivity mechanisms for the lysosomal K + channel TMEM175.
Elife, 9, 2020
6WCB
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BU of 6wcb by Molmil
Human open state TMEM175 in CsCl
分子名称: CESIUM ION, Endosomal/lysosomal potassium channel TMEM175
著者Oh, S, Paknejad, N, Hite, R.K.
登録日2020-03-30
公開日2020-04-15
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.17 Å)
主引用文献Gating and selectivity mechanisms for the lysosomal K + channel TMEM175.
Elife, 9, 2020
8DHM
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BU of 8dhm by Molmil
Human TMEM175 in complex with 4-aminopyridine
分子名称: 4-AMINOPYRIDINE, Endosomal/lysosomal potassium channel TMEM175, POTASSIUM ION
著者Oh, S, Hite, R.K.
登録日2022-06-27
公開日2022-11-23
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (2.73 Å)
主引用文献Mechanism of 4-aminopyridine inhibition of the lysosomal channel TMEM175.
Proc.Natl.Acad.Sci.USA, 119, 2022
7UNL
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BU of 7unl by Molmil
Human TMEM175 in an open state
分子名称: Endosomal/lysosomal potassium channel TMEM175, POTASSIUM ION
著者Oh, S, Hite, R.K.
登録日2022-04-11
公開日2022-06-01
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (2.45 Å)
主引用文献Differential ion dehydration energetics explains selectivity in the non-canonical lysosomal K + channel TMEM175.
Elife, 11, 2022
7UNM
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BU of 7unm by Molmil
Human TMEM175 in an closed state
分子名称: Endosomal/lysosomal potassium channel TMEM175, POTASSIUM ION
著者Oh, S, Hite, R.K.
登録日2022-04-11
公開日2022-06-29
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (2.61 Å)
主引用文献Differential ion dehydration energetics explains selectivity in the non-canonical lysosomal K + channel TMEM175.
Elife, 11, 2022
5UX3
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BU of 5ux3 by Molmil
RNA hairpin structure containing 2-MeImpG monomer analogue and 2-MeImp-oligomer analogue
分子名称: 5'-O-[(S)-hydroxy(4-methyl-1H-imidazol-5-yl)phosphoryl]guanosine, RNA (25-MER), RNA (5'-D(*(RG))-R(P*CP*AP*CP*CP*UP*CP*A)-3')
著者Zhang, W, Oh, S.S, Szostak, J.W.
登録日2017-02-21
公開日2018-02-21
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural Rationale for the Enhanced Catalysis of Nonenzymatic RNA Primer Extension by a Downstream Oligonucleotide.
J. Am. Chem. Soc., 140, 2018
5UZ6
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BU of 5uz6 by Molmil
RNA hairpin structure containing 2-MeImp-oligo analogue
分子名称: RNA (25-MER), RNA (5'-D(*(8OS))-R(P*CP*AP*CP*CP*UP*CP*A)-3')
著者Zhang, W, Oh, S.S, Szostak, J.W.
登録日2017-02-24
公開日2018-02-21
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural Rationale for the Enhanced Catalysis of Nonenzymatic RNA Primer Extension by a Downstream Oligonucleotide.
J. Am. Chem. Soc., 140, 2018
5CFY
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BU of 5cfy by Molmil
CRYSTAL STRUCTURE OF GLTPH R397A IN COMPLEX WITH NA+ AND L-ASP
分子名称: 425aa long hypothetical proton glutamate symport protein, ASPARTIC ACID, SODIUM ION
著者Boudker, O, Oh, S.
登録日2015-07-08
公開日2016-04-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Coupled ion binding and structural transitions along the transport cycle of glutamate transporters.
Elife, 3, 2014
6CTF
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BU of 6ctf by Molmil
Crystal structure of GltPh fast mutant - R276S/M395R
分子名称: ASPARTIC ACID, Glutamate transporter homolog, SODIUM ION
著者Boudker, O, Oh, S.
登録日2018-03-23
公開日2018-10-10
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (4.05 Å)
主引用文献Kinetic mechanism of coupled binding in sodium-aspartate symporter GltPh.
Elife, 7, 2018
4OYE
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BU of 4oye by Molmil
Crystal structure of GltPh R397A in apo
分子名称: 425aa long hypothetical proton glutamate symport protein
著者Boudker, O, Oh, S.
登録日2014-02-11
公開日2014-09-17
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Coupled ion binding and structural transitions along the transport cycle of glutamate transporters.
Elife, 3, 2014
4OYF
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BU of 4oyf by Molmil
Crystal structure of GLTPH R397A IN Sodium-bound state
分子名称: GLUTAMATE SYMPORT PROTEIN, SODIUM ION
著者Boudker, O, Oh, S, Verdon, G, Serio, R.
登録日2014-02-11
公開日2014-08-13
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.41 Å)
主引用文献Coupled ion binding and structural transitions along the transport cycle of glutamate transporters.
Elife, 3, 2014

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件を2024-10-09に公開中

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