4DGT
 
 | | Crystal structure of PLP-bound putative aminotransferase from Clostridium difficile 630 crystallized with magnesium formate | | Descriptor: | CHLORIDE ION, MAGNESIUM ION, PYRIDOXAL-5'-PHOSPHATE, ... | | Authors: | Shabalin, I.G, Onopriyenko, O, Kudritska, M, Chruszcz, M, Grimshaw, S, Porebski, P.J, Cooper, D.R, Savchenko, A, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2012-01-26 | | Release date: | 2012-02-08 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Crystal structures of putative aminotransferase from Clostridium difficile
630
to be published
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4DHQ
 | | Small-molecule inhibitors of 14-3-3 protein-protein interactions from virtual screening | | Descriptor: | (2-{2-[(3-chlorophenyl)amino]-2-oxoethoxy}phenyl)phosphonic acid, 14-3-3 protein sigma, CHLORIDE ION, ... | | Authors: | Thiel, P, Roeglin, L, Kohlbacher, O, Ottmann, C. | | Deposit date: | 2012-01-30 | | Release date: | 2013-07-31 | | Last modified: | 2013-09-04 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Virtual screening and experimental validation reveal novel small-molecule inhibitors of 14-3-3 protein-protein interactions.
Chem.Commun.(Camb.), 49, 2013
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1H80
 | | 1,3-ALPHA-1,4-BETA-D-GALACTOSE-4-SULFATE- 3,6-ANHYDRO-D-GALACTOSE-2-SULFATE 4 GALACTOHYDROLASE | | Descriptor: | CALCIUM ION, CHLORIDE ION, GLYCEROL, ... | | Authors: | Michel, G, Chantalat, L, Dideberg, O. | | Deposit date: | 2001-01-22 | | Release date: | 2001-11-27 | | Last modified: | 2018-10-24 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | The Iota-Carrageenase of Alteromonas Fortis. A Beta-Helix Fold-Containing Enzyme for the Degradation of a Highly Polyanionic Polysaccharide
J.Biol.Chem., 276, 2001
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4DHM
 | | Small-molecule inhibitors of 14-3-3 protein-protein interactions from virtual screening | | Descriptor: | 14-3-3 protein sigma, CHLORIDE ION, GLYCEROL, ... | | Authors: | Thiel, P, Roeglin, L, Kohlbacher, O, Ottmann, C. | | Deposit date: | 2012-01-30 | | Release date: | 2013-07-31 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Virtual screening and experimental validation reveal novel small-molecule inhibitors of 14-3-3 protein-protein interactions.
Chem.Commun.(Camb.), 49, 2013
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4DHT
 | | Small-molecule inhibitors of 14-3-3 protein-protein interactions from virtual screening | | Descriptor: | 14-3-3 PROTEIN SIGMA, CHLORIDE ION, GLYCEROL, ... | | Authors: | Thiel, P, Roeglin, L, Kohlbacher, O, Ottmann, C. | | Deposit date: | 2012-01-30 | | Release date: | 2013-07-31 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Virtual screening and experimental validation reveal novel small-molecule inhibitors of 14-3-3 protein-protein interactions.
Chem.Commun.(Camb.), 49, 2013
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4E3O
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4DBQ
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1GP1
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7OCA
 | | Resting state full-length GluA1/A2 heterotertramer in complex with TARP gamma 8 and CNIH2 | | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Zhang, D, Watson, J.F, Matthews, P.M, Cais, O, Greger, I.H. | | Deposit date: | 2021-04-26 | | Release date: | 2021-06-09 | | Last modified: | 2021-06-30 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Gating and modulation of a hetero-octameric AMPA glutamate receptor.
Nature, 594, 2021
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7OCC
 | | NTD of resting state GluA1/A2 heterotertramer | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor 1, ... | | Authors: | Zhang, D, Watson, J.F, Matthews, P.M, Cais, O, Greger, I.H. | | Deposit date: | 2021-04-26 | | Release date: | 2021-06-09 | | Last modified: | 2021-06-30 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Gating and modulation of a hetero-octameric AMPA glutamate receptor.
Nature, 594, 2021
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7OCD
 | | Resting state GluA1/A2 heterotetramer in complex with auxiliary subunit TARP gamma 8 (LBD-TMD) | | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 6-nitro-2,3-bis(oxidanylidene)-1,4-dihydrobenzo[f]quinoxaline-7-sulfonamide, Glutamate receptor 2, ... | | Authors: | Zhang, D, Watson, J.F, Matthews, P.M, Cais, O, Greger, I.H. | | Deposit date: | 2021-04-26 | | Release date: | 2021-06-09 | | Last modified: | 2021-06-30 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Gating and modulation of a hetero-octameric AMPA glutamate receptor.
Nature, 594, 2021
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7OCE
 | | Resting state GluA1/A2 AMPA receptor in complex with TARP gamma 8 and CNIH2 (LBD-TMD) | | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 6-nitro-2,3-bis(oxidanylidene)-1,4-dihydrobenzo[f]quinoxaline-7-sulfonamide, CHOLESTEROL, ... | | Authors: | Zhang, D, Watson, J.F, Matthews, P.M, Cais, O, Greger, I.H. | | Deposit date: | 2021-04-26 | | Release date: | 2021-06-09 | | Last modified: | 2021-06-30 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Gating and modulation of a hetero-octameric AMPA glutamate receptor.
Nature, 594, 2021
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7OCF
 | | Active state GluA1/A2 AMPA receptor in complex with TARP gamma 8 and CNIH2 (LBD-TMD) | | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CYCLOTHIAZIDE, GLUTAMIC ACID, ... | | Authors: | Zhang, D, Watson, J.F, Matthews, P.M, Cais, O, Greger, I.H. | | Deposit date: | 2021-04-26 | | Release date: | 2021-06-09 | | Last modified: | 2021-06-30 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Gating and modulation of a hetero-octameric AMPA glutamate receptor.
Nature, 594, 2021
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7NVH
 | | Cryo-EM structure of the mycolic acid transporter MmpL3 from M. tuberculosis | | Descriptor: | Lauryl Maltose Neopentyl Glycol, Trehalose monomycolate exporter MmpL3 | | Authors: | Adams, O, Deme, J.C, Parker, J.L, Lea, S.M, Newstead, S. | | Deposit date: | 2021-03-15 | | Release date: | 2021-06-16 | | Last modified: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Cryo-EM structure and resistance landscape of M. tuberculosis MmpL3: An emergent therapeutic target.
Structure, 29, 2021
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7ODS
 | | State B of the human mitoribosomal large subunit assembly intermediate | | Descriptor: | 16S mitochondrial rRNA, DNA (30-MER),16S mitochondrial rRNA, 39S ribosomal protein L10, ... | | Authors: | Lenarcic, T, Jaskolowski, M, Leibundgut, M, Scaiola, A, Schoenhut, T, Saurer, M, Lee, R.G, Rackham, O, Filipovska, A, Ban, N. | | Deposit date: | 2021-04-30 | | Release date: | 2021-06-23 | | Last modified: | 2023-11-15 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Stepwise maturation of the peptidyl transferase region of human mitoribosomes.
Nat Commun, 12, 2021
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7ODR
 | | State A of the human mitoribosomal large subunit assembly intermediate | | Descriptor: | 16S mitochondrial rRNA, DNA (31-MER),16S mitochondrial rRNA, 39S ribosomal protein L10, ... | | Authors: | Lenarcic, T, Jaskolowski, M, Leibundgut, M, Scaiola, A, Schoenhut, T, Saurer, M, Lee, R.G, Rackham, O, Filipovska, A, Ban, N. | | Deposit date: | 2021-04-30 | | Release date: | 2021-06-23 | | Last modified: | 2023-11-15 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Stepwise maturation of the peptidyl transferase region of human mitoribosomes.
Nat Commun, 12, 2021
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7ODT
 | | State C of the human mitoribosomal large subunit assembly intermediate | | Descriptor: | 16S mitochondrial rRNA, 39S ribosomal protein L10, mitochondrial, ... | | Authors: | Lenarcic, T, Jaskolowski, M, Leibundgut, M, Scaiola, A, Schoenhut, T, Saurer, M, Lee, R.G, Rackham, O, Filipovska, A, Ban, N. | | Deposit date: | 2021-04-30 | | Release date: | 2021-06-23 | | Last modified: | 2023-11-15 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Stepwise maturation of the peptidyl transferase region of human mitoribosomes.
Nat Commun, 12, 2021
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7OG7
 | | Crystal structure of the copper chaperone NosL from Shewanella denitrificans | | Descriptor: | ACETONITRILE, COPPER (I) ION, NosL, ... | | Authors: | Prasser, B, Schoener, L, Zhang, L, Einsle, O. | | Deposit date: | 2021-05-06 | | Release date: | 2021-07-07 | | Last modified: | 2024-06-19 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | The Copper Chaperone NosL Forms a Heterometal Site for Cu Delivery to Nitrous Oxide Reductase.
Angew.Chem.Int.Ed.Engl., 60, 2021
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2JP6
 | | Structural and functional characterization of the recombinant form of the Kv1.3 channel blocker Tc32 | | Descriptor: | Potassium channel toxin alpha-KTx 18.1 | | Authors: | Stehling, E.G, Sforca, M.L, Zanchin, N.I, Pignatelli, A, Belluzzi, O, Spisni, A, Pertinhez, T.A. | | Deposit date: | 2007-04-26 | | Release date: | 2008-04-29 | | Last modified: | 2023-12-20 | | Method: | SOLUTION NMR | | Cite: | Structural and functional characterization of the recombinant form of the
Kv1.3 channel blocker Tc32
To be Published
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2JPP
 | | Structural basis of RsmA/CsrA RNA recognition: Structure of RsmE bound to the Shine-Dalgarno sequence of hcnA mRNA | | Descriptor: | RNA (5'-R(*GP*GP*GP*CP*UP*UP*CP*AP*CP*GP*GP*AP*UP*GP*AP*AP*GP*CP*CP*C)-3'), Translational repressor | | Authors: | Schubert, M, Lapouge, K, Duss, O, Oberstrass, F.C, Jelesarov, I, Haas, D, Allain, F.H.-T. | | Deposit date: | 2007-05-21 | | Release date: | 2007-08-21 | | Last modified: | 2023-12-20 | | Method: | SOLUTION NMR | | Cite: | Molecular basis of messenger RNA recognition by the specific bacterial repressing clamp RsmA/CsrA
Nat.Struct.Mol.Biol., 14, 2007
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2JON
 | | Solution structure of the C-terminal domain Ole e 9 | | Descriptor: | Beta-1,3-glucanase | | Authors: | Trevino, M.A, Palomares, O, Castrillo, I, Villalba, M, Rodriguez, R, Rico, M, Santoro, J, Bruix, M. | | Deposit date: | 2007-03-14 | | Release date: | 2008-01-29 | | Last modified: | 2023-12-20 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the C-terminal domain of Ole e 9, a major allergen of olive pollen
Protein Sci., 17, 2008
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2J9W
 | | Structural insight into the ESCRT-I-II link and its role in MVB trafficking | | Descriptor: | VPS28-PROV PROTEIN | | Authors: | Gill, D.J, Teo, H.L, Sun, J, Perisic, O, Veprintsev, D.B, Emr, S.D, Williams, R.L. | | Deposit date: | 2006-11-16 | | Release date: | 2007-01-23 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | Structural Insight Into the Escrt-I/-II Link and its Role in Mvb Trafficking.
Embo J., 26, 2007
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2J9U
 | | 2 Angstrom X-ray structure of the yeast ESCRT-I Vps28 C-terminus in complex with the NZF-N domain from ESCRT-II | | Descriptor: | VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 28, VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 36, ZINC ION | | Authors: | Gill, D.J, Teo, H.L, Sun, J, Perisic, O, Veprintsev, D.B, Emr, S.D, Williams, R.L. | | Deposit date: | 2006-11-16 | | Release date: | 2007-01-23 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural Insight Into the Escrt-I/-II Link and its Role in Mvb Trafficking.
Embo J., 26, 2007
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2JLN
 | | Structure of Mhp1, a nucleobase-cation-symport-1 family transporter | | Descriptor: | MERCURY (II) ION, MHP1, SODIUM ION | | Authors: | Weyand, S, Shimamura, T, Yajima, S, Suzuki, S, Mirza, O, Krusong, K, Carpenter, E.P, Rutherford, N.G, Hadden, J.M, O'Reilly, J, Ma, P, Saidijam, M, Patching, S.G, Hope, R.J, Norbertczak, H.T, Roach, P.C.J, Iwata, S, Henderson, P.J.F, Cameron, A.D. | | Deposit date: | 2008-09-11 | | Release date: | 2008-10-28 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.85 Å) | | Cite: | Structure and Molecular Mechanism of a Nucleobase-Cation-Symport-1 Family Transporter.
Science, 322, 2008
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2K8D
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