4CZ9
 
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4CZV
 | | Structure of the Neurospora crassa Pan2 WD40 domain | | 分子名称: | CHLORIDE ION, GLYCEROL, PAB-DEPENDENT POLY(A)-SPECIFIC RIBONUCLEASE SUBUNIT PAN2 | | 著者 | Peter, D, Jonas, S, Izaurralde, E, Weichenrieder, O. | | 登録日 | 2014-04-22 | | 公開日 | 2014-06-04 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | An Asymmetric Pan3 Dimer Recruits a Single Pan2 Exonuclease to Mediate Mrna Deadenylation and Decay.
Nat.Struct.Mol.Biol., 21, 2014
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4D1W
 | | A H224Y mutant for VIM-7 from Pseudomonas aeruginosa | | 分子名称: | METALLO-B-LACTAMASE, ZINC ION | | 著者 | Leiros, H.-K.S, Skagseth, S, Edvardsen, K.S.W, Lorentzen, M.S, Bjerga, G.E.K, Leiros, I, Samuelsen, O. | | 登録日 | 2014-05-05 | | 公開日 | 2014-06-25 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | His224 Alters the R2 Drug Binding Site and Phe218 Influences the Catalytic Efficiency in the Metallo-Beta-Lactamase Vim-7.
Antimicrob.Agents Chemother., 58, 2014
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4CO8
 | | Structure of the DNA binding ETS domain of human ETV4 | | 分子名称: | 1,2-ETHANEDIOL, ETS TRANSLOCATION VARIANT 4 | | 著者 | Newman, J.A, Cooper, C.D.O, Shrestha, L, Burgess-Brown, N, Kopec, J, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O. | | 登録日 | 2014-01-27 | | 公開日 | 2014-02-05 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.05 Å) | | 主引用文献 | Structures of the Ets Domains of Transcription Factors Etv1, Etv4, Etv5 and Fev: Determinants of DNA Binding and Redox Regulation by Disulfide Bond Formation.
J.Biol.Chem., 290, 2015
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4CSG
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4CZY
 | | Complex of Neurospora crassa PAN2 (WD40-CS1) with PAN3 (pseudokinase and C-term) | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, MAGNESIUM ION, PAB-DEPENDENT POLY(A)-SPECIFIC RIBONUCLEASE SUBUNIT PAN2, ... | | 著者 | Jonas, S, Izaurralde, E, Weichenrieder, O. | | 登録日 | 2014-04-22 | | 公開日 | 2014-06-04 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | An Asymmetric Pan3 Dimer Recruits a Single Pan2 Exonuclease to Mediate Mrna Deadenylation and Decay.
Nat.Struct.Mol.Biol., 21, 2014
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4CZB
 | | Structure of the sodium proton antiporter MjNhaP1 from Methanocaldococcus jannaschii at pH 8. | | 分子名称: | NA(+)/H(+) ANTIPORTER 1, POTASSIUM ION, TRIS(HYDROXYETHYL)AMINOMETHANE | | 著者 | Woehlert, D, Paulino, C, Kapotova, E, Kuhlbrandt, W, Yildiz, O. | | 登録日 | 2014-04-16 | | 公開日 | 2014-12-10 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | 3D Em Map of the Sodium Proton Antiporter Mjnhap1 from Methanocaldococcus Jannaschii
Elife, 3, 2014
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4D0M
 | | Phosphatidylinositol 4-kinase III beta in a complex with Rab11a-GTP- gamma-S and the Rab-binding domain of FIP3 | | 分子名称: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, N-(5-(4-CHLORO-3-(2-HYDROXY-ETHYLSULFAMOYL)- PHENYLTHIAZOLE-2-YL)-ACETAMIDE, ... | | 著者 | Burke, J.E, Inglis, A.J, Perisic, O, Masson, G.R, McLaughlin, S.H, Rutaganira, F, Shokat, K.M, Williams, R.L. | | 登録日 | 2014-04-29 | | 公開日 | 2014-05-28 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (6 Å) | | 主引用文献 | Structures of Pi4Kiiibeta Complexes Show Simultaneous Recruitment of Rab11 and its Effectors.
Science, 344, 2014
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4D1U
 | | A D120A mutant of VIM-7 from Pseudomonas aeruginosa | | 分子名称: | METALLO-B-LACTAMASE, ZINC ION | | 著者 | Leiros, H.-K.S, Skagseth, S, Edvardsen, K.S.W, Lorentzen, M.S, Bjerga, G.E.K, Leiros, I, Samuelsen, O. | | 登録日 | 2014-05-05 | | 公開日 | 2014-06-25 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | His224 Alters the R2 Drug Binding Site and Phe218 Influences the Catalytic Efficiency in the Metallo-Beta-Lactamase Vim-7.
Antimicrob.Agents Chemother., 58, 2014
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4D0K
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4D1T
 | | High resolution structure of native tVIM-7 from Pseudomonas aeruginosa | | 分子名称: | METALLO-B-LACTAMASE, ZINC ION | | 著者 | Leiros, H.-K.S, Skagseth, S, Edvardsen, K.S.W, Lorentzen, M.S, Bjerga, G.E.K, Leiros, I, Samuelsen, O. | | 登録日 | 2014-05-05 | | 公開日 | 2014-06-25 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | His224 Alters the R2 Drug Binding Site and Phe218 Influences the Catalytic Efficiency in the Metallo-Beta-Lactamase Vim-7.
Antimicrob.Agents Chemother., 58, 2014
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4D1V
 | | A F218Y mutant of VIM-7 from Pseudomonas aeruginosa | | 分子名称: | METALLO-B-LACTAMASE, ZINC ION | | 著者 | Leiros, H.-K.S, Skagseth, S, Edvardsen, K.S.W, Lorentzen, M.S, Bjerga, G.E.K, Leiros, I, Samuelsen, O. | | 登録日 | 2014-05-05 | | 公開日 | 2014-06-25 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | His224 Alters the R2 Drug Binding Site and Phe218 Influences the Catalytic Efficiency in the Metallo-Beta-Lactamase Vim-7.
Antimicrob.Agents Chemother., 58, 2014
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4D49
 | | Crystal structure of computationally designed armadillo repeat proteins for modular peptide recognition. | | 分子名称: | ARGININE, ARMADILLO REPEAT PROTEIN ARM00027, POLY ARG DECAPEPTIDE | | 著者 | Reichen, C, Forzani, C, Zhou, T, Parmeggiani, F, Fleishman, S.J, Mittl, P.R.E, Madhurantakam, C, Honegger, A, Ewald, C, Zerbe, O, Baker, D, Caflisch, A, Pluckthun, A. | | 登録日 | 2014-10-27 | | 公開日 | 2016-01-13 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | Computationally Designed Armadillo Repeat Proteins for Modular Peptide Recognition.
J.Mol.Biol., 428, 2016
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4D4E
 | | Crystal structure of computationally designed armadillo repeat proteins for modular peptide recognition. | | 分子名称: | ARMADILLO REPEAT PROTEIN ARM00016, GLYCEROL | | 著者 | Reichen, C, Forzani, C, Zhou, T, Parmeggiani, F, Fleishman, S.J, Mittl, P.R.E, Madhurantakam, C, Honegger, A, Ewald, C, Zerbe, O, Baker, D, Caflisch, A, Pluckthun, A. | | 登録日 | 2014-10-28 | | 公開日 | 2016-01-13 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Computationally Designed Armadillo Repeat Proteins for Modular Peptide Recognition.
J.Mol.Biol., 428, 2016
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4DBR
 | | Myosin VI D179Y (MD) pre-powerstroke state | | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Pylypenko, O, Sweeney, H.L, Houdusse, A. | | 登録日 | 2012-01-16 | | 公開日 | 2013-01-30 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Mutations in myosin VI that cause a loss of coordination between heads provide insights into the structural changes underlying force generation and the importance of gating
To be Published
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3KVW
 | | Crystal Structure of dual-specificity tyrosine phosphorylation regulated kinase 2 (DYRK2) in complex with an indirubin ligand | | 分子名称: | (2Z,3E)-7'-bromo-3-(hydroxyimino)-2'-oxo-1,1',2',3-tetrahydro-2,3'-biindole-5-carboxylic acid, CHLORIDE ION, Dual specificity tyrosine-phosphorylation-regulated kinase 2 | | 著者 | Filippakopoulos, P, Myrianthopoulos, V, Kritsanida, M, Magiatis, P, Skaltsounis, A.L, Soundararajan, M, Krojer, T, Gileadi, O, Hapka, E, Fedorov, O, Berridge, G, Wang, J, Shrestha, L, Vollmar, M, von Delft, F, Arrowsmith, C.H, Edwards, A, Weigelt, J, Bountra, C, Mikros, E, Knapp, S, Structural Genomics Consortium (SGC) | | 登録日 | 2009-11-30 | | 公開日 | 2010-01-05 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | | 主引用文献 | Crystal Structure of dual-specificity tyrosine phosphorylation regulated kinase 2 (DYRK2) in complex with an indirubin ligand
To be Published
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4E0B
 | | 2.17 Angstrom resolution crystal structure of malate dehydrogenase from Vibrio vulnificus CMCP6 | | 分子名称: | ACETATE ION, Malate dehydrogenase | | 著者 | Halavaty, A.S, Wawrzak, Z, Onopriyenko, O, Kwon, K, Anderson, W.F, Savchenko, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2012-03-02 | | 公開日 | 2012-03-21 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | | 主引用文献 | 2.17 Angstrom resolution crystal structure of malate dehydrogenase from Vibrio vulnificus CMCP6
To be Published
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4DHS
 | | Small-molecule inhibitors of 14-3-3 protein-protein interactions from virtual screening | | 分子名称: | (2-{2-[(3,5-dichlorophenyl)amino]-2-oxoethoxy}phenyl)phosphonic acid, 14-3-3 PROTEIN SIGMA, CHLORIDE ION, ... | | 著者 | Thiel, P, Roeglin, L, Kohlbacher, O, Ottmann, C. | | 登録日 | 2012-01-30 | | 公開日 | 2013-07-31 | | 最終更新日 | 2013-09-04 | | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | | 主引用文献 | Virtual screening and experimental validation reveal novel small-molecule inhibitors of 14-3-3 protein-protein interactions.
Chem.Commun.(Camb.), 49, 2013
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7P0O
 | | mitoNEET bound to M1 molecule | | 分子名称: | 2-benzamido-4-[(2~{R})-1,2,3,4-tetrahydronaphthalen-2-yl]thiophene-3-carboxylic acid, 2-benzamido-4-[(2~{S})-1,2,3,4-tetrahydronaphthalen-2-yl]thiophene-3-carboxylic acid, CDGSH iron-sulfur domain-containing protein 1, ... | | 著者 | Livnah, O, Eisenberg-Domovich, Y, Marjault, H.B, Nechushtai, R. | | 登録日 | 2021-06-30 | | 公開日 | 2022-05-25 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | An anti-diabetic drug targets NEET (CISD) proteins through destabilization of their [2Fe-2S] clusters.
Commun Biol, 5, 2022
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7P0P
 | | NAF-1 bound to M1 molecule | | 分子名称: | 2-benzamido-4-[(2~{R})-1,2,3,4-tetrahydronaphthalen-2-yl]thiophene-3-carboxylic acid, CDGSH iron-sulfur domain-containing protein 2, FE2/S2 (INORGANIC) CLUSTER | | 著者 | Livnah, O, Eisenberg-Domovich, Y, Marjault, H.B, Nechushtai, R. | | 登録日 | 2021-06-30 | | 公開日 | 2022-05-25 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | | 主引用文献 | An anti-diabetic drug targets NEET (CISD) proteins through destabilization of their [2Fe-2S] clusters.
Commun Biol, 5, 2022
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3LQY
 | | Crystal structure of putative isochorismatase hydrolase from Oleispira antarctica | | 分子名称: | GLYCEROL, putative isochorismatase hydrolase | | 著者 | Goral, A, Chruszcz, M, Kagan, O, Cymborowski, M, Savchenko, A, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2010-02-10 | | 公開日 | 2010-03-16 | | 最終更新日 | 2022-04-13 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Crystal structure of a putative isochorismatase hydrolase from Oleispira antarctica.
J.Struct.Funct.Genom., 13, 2012
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6HNF
 | | Structure in solution of human fibronectin type III-domain 14 | | 分子名称: | Fibronectin | | 著者 | Zhong, X, Arnolds, O, Krenczyk, O, Gajewski, J, Puetz, S, Herrmann, C, Stoll, R. | | 登録日 | 2018-09-14 | | 公開日 | 2018-10-10 | | 最終更新日 | 2024-06-19 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The Structure in Solution of Fibronectin Type III Domain 14 Reveals Its Synergistic Heparin Binding Site.
Biochemistry, 57, 2018
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4YQE
 | | Crystal structure of E. coli WrbA in complex with benzoquinone | | 分子名称: | 1,4-benzoquinone, FLAVIN MONONUCLEOTIDE, NAD(P)H dehydrogenase (quinone) | | 著者 | Degtjarik, O, Brynda, J, Ettrichova, O, Carey, J, Kuta Smatanova, I, Ettrich, R. | | 登録日 | 2015-03-13 | | 公開日 | 2016-05-25 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.33 Å) | | 主引用文献 | Quantum Calculations Indicate Effective Electron Transfer between FMN and Benzoquinone in a New Crystal Structure of Escherichia coli WrbA.
J.Phys.Chem.B, 120, 2016
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1OME
 | | CRYSTAL STRUCTURE OF THE OMEGA LOOP DELETION MUTANT (RESIDUES 163-178 DELETED) OF BETA-LACTAMASE FROM STAPHYLOCOCCUS AUREUS PC1 | | 分子名称: | BETA-LACTAMASE, CHLORIDE ION | | 著者 | Banerjee, S, Pieper, U, Herzberg, O. | | 登録日 | 1998-02-09 | | 公開日 | 1998-05-27 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Role of the omega-loop in the activity, substrate specificity, and structure of class A beta-lactamase.
Biochemistry, 37, 1998
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4Z2V
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