3EDZ
 
 | | Crystal structure of catalytic domain of TACE with hydroxamate inhibitor | | 分子名称: | ADAM 17, CITRIC ACID, N-{(2R)-2-[2-(hydroxyamino)-2-oxoethyl]-4-methylpentanoyl}-3-methyl-L-valyl-N-(2-aminoethyl)-L-alaninamide, ... | | 著者 | Mazzola, R.D, Zhu, Z, Sinning, L, McKittrick, B, Lavey, B, Spitler, J, Kozlowski, J, Neng-Yang, S, Zhou, G, Guo, Z, Orth, P, Madison, V, Sun, J, Lundell, D, Niu, X. | | 登録日 | 2008-09-03 | | 公開日 | 2008-09-23 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Discovery of novel hydroxamates as highly potent tumor necrosis factor-alpha converting enzyme inhibitors. Part II: optimization of the S3' pocket.
Bioorg.Med.Chem.Lett., 18, 2008
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2FV5
 | | Crystal structure of TACE in complex with IK682 | | 分子名称: | (2R)-N-HYDROXY-2-[(3S)-3-METHYL-3-{4-[(2-METHYLQUINOLIN-4-YL)METHOXY]PHENYL}-2-OXOPYRROLIDIN-1-YL]PROPANAMIDE, ADAM 17, ZINC ION | | 著者 | Orth, P, Niu, X. | | 登録日 | 2006-01-30 | | 公開日 | 2006-07-04 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | IK682, a tight binding inhibitor of TACE.
Arch.Biochem.Biophys., 451, 2006
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2N00
 | | NMR Solution structure of AIM2 PYD from Mus musculus | | 分子名称: | Interferon-inducible protein AIM2 | | 著者 | Hou, X, Niu, X. | | 登録日 | 2015-03-01 | | 公開日 | 2015-05-27 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The NMR solution structure of AIM2 PYD domain from Mus musculus reveals a distinct alpha 2-alpha 3 helix conformation from its human homologues
Biochem.Biophys.Res.Commun., 461, 2015
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7EES
 | | NMR structure of the lasso peptide rubrivimycin | | 分子名称: | GLY-THR-ILE-ASP-PRO-GLN-ASN-SER-GLU-GLU-HIS-PRO-VAL-LEU-SER-ARG-ARG-LEU-GLU-ASN | | 著者 | Xiu, H, Niu, X, Zhu, S. | | 登録日 | 2021-03-19 | | 公開日 | 2022-03-23 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Insight into the biosynthesis of rubrivimycin provides new clue for the evolution of lasso peptides
To Be Published
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