2GH6
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![BU of 2gh6 by Molmil](/molmil-images/mine/2gh6) | Crystal structure of a HDAC-like protein with 9,9,9-trifluoro-8-oxo-N-phenylnonan amide bound | Descriptor: | 9,9,9-TRIFLUORO-8-OXO-N-PHENYLNONANAMIDE, Histone deacetylase-like amidohydrolase, POTASSIUM ION, ... | Authors: | Nielsen, T.K, Hildmann, C, Riester, D, Wegener, D, Schwienhorst, A, Ficner, R. | Deposit date: | 2006-03-26 | Release date: | 2007-03-20 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.203 Å) | Cite: | Complex structure of a bacterial class 2 histone deacetylase homologue with a trifluoromethylketone inhibitor. Acta Crystallogr.,Sect.F, 63, 2007
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6DEJ
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3KXU
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![BU of 3kxu by Molmil](/molmil-images/mine/3kxu) | Crystal structure of human ferritin FTL498InsTC pathogenic mutant | Descriptor: | CADMIUM ION, Ferritin, SULFATE ION | Authors: | Granier, T, Gallois, B, Langlois d'Estaintot, B, Arosio, P. | Deposit date: | 2009-12-04 | Release date: | 2010-02-09 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Mutant ferritin L-chains that cause neurodegeneration act in a dominant-negative manner to reduce ferritin iron incorporation. J.Biol.Chem., 285, 2010
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8OVL
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7Q6I
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![BU of 7q6i by Molmil](/molmil-images/mine/7q6i) | Vibrio maritimus FtsA 1-396 ATP and FtsN 1-29, bent tetramers in double filament arrangement | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Cell division protein FtsA, Cell division protein FtsN (polyAla model), ... | Authors: | Nierhaus, T, Kureisaite-Ciziene, D, Lowe, J. | Deposit date: | 2021-11-07 | Release date: | 2022-09-21 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | Bacterial divisome protein FtsA forms curved antiparallel double filaments when binding to FtsN. Nat Microbiol, 7, 2022
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4OHS
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![BU of 4ohs by Molmil](/molmil-images/mine/4ohs) | The structure of a far-red fluorescent protein, AQ143 | Descriptor: | CHLORIDE ION, FAR-RED FLUORESCENT PROTEIN AQ143 | Authors: | Wannier, T.M, Mayo, S.L. | Deposit date: | 2014-01-17 | Release date: | 2014-02-26 | Last modified: | 2014-08-06 | Method: | X-RAY DIFFRACTION (2.19 Å) | Cite: | The structure of a far-red fluorescent protein, AQ143, shows evidence in support of reported red-shifting chromophore interactions. Protein Sci., 23, 2014
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2V6C
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1IES
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![BU of 1ies by Molmil](/molmil-images/mine/1ies) | TETRAGONAL CRYSTAL STRUCTURE OF NATIVE HORSE SPLEEN FERRITIN | Descriptor: | CADMIUM ION, FERRITIN | Authors: | Granier, T, Gallois, B, Dautant, A, Langlois D'Estaintot, B, Precigoux, G. | Deposit date: | 1996-05-28 | Release date: | 1997-01-11 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Comparison of the structures of the cubic and tetragonal forms of horse-spleen apoferritin. Acta Crystallogr.,Sect.D, 53, 1997
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7Q6D
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![BU of 7q6d by Molmil](/molmil-images/mine/7q6d) | E. coli FtsA 1-405 ATP 3 Ni | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Cell division protein FtsA, MAGNESIUM ION, ... | Authors: | Nierhaus, T, Kureisaite-Ciziene, D, Lowe, J. | Deposit date: | 2021-11-06 | Release date: | 2022-09-21 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Bacterial divisome protein FtsA forms curved antiparallel double filaments when binding to FtsN. Nat Microbiol, 7, 2022
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7Q6G
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![BU of 7q6g by Molmil](/molmil-images/mine/7q6g) | Xenorhabdus poinarii FtsA 1-396 ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Cell division protein FtsA, MAGNESIUM ION | Authors: | Nierhaus, T, Kureisaite-Ciziene, D, Lowe, J. | Deposit date: | 2021-11-07 | Release date: | 2022-09-21 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Bacterial divisome protein FtsA forms curved antiparallel double filaments when binding to FtsN. Nat Microbiol, 7, 2022
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7Q6F
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![BU of 7q6f by Molmil](/molmil-images/mine/7q6f) | Vibrio maritimus FtsA 1-396 ATP, double filament | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Cell division protein FtsA, MAGNESIUM ION | Authors: | Nierhaus, T, Kureisaite-Ciziene, D, Lowe, J. | Deposit date: | 2021-11-07 | Release date: | 2022-09-21 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (3.31 Å) | Cite: | Bacterial divisome protein FtsA forms curved antiparallel double filaments when binding to FtsN. Nat Microbiol, 7, 2022
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1ZZ0
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![BU of 1zz0 by Molmil](/molmil-images/mine/1zz0) | Crystal structure of a HDAC-like protein with acetate bound | Descriptor: | ACETATE ION, Histone deacetylase-like amidohydrolase, POTASSIUM ION, ... | Authors: | Nielsen, T.K, Hildmann, C, Dickmanns, A, Schwienhorst, A, Ficner, R. | Deposit date: | 2005-06-13 | Release date: | 2005-11-29 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal structure of a bacterial class 2 histone deacetylase homologue J.Mol.Biol., 354, 2005
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1ZZ3
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![BU of 1zz3 by Molmil](/molmil-images/mine/1zz3) | Crystal structure of a HDAC-like protein with CypX bound | Descriptor: | 3-CYCLOPENTYL-N-HYDROXYPROPANAMIDE, Histone deacetylase-like amidohydrolase, POTASSIUM ION, ... | Authors: | Nielsen, T.K, Hildmann, C, Dickmanns, A, Schwienhorst, A, Ficner, R. | Deposit date: | 2005-06-13 | Release date: | 2005-11-29 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | Crystal structure of a bacterial class 2 histone deacetylase homologue J.Mol.Biol., 354, 2005
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1ZZ1
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![BU of 1zz1 by Molmil](/molmil-images/mine/1zz1) | Crystal structure of a HDAC-like protein with SAHA bound | Descriptor: | Histone deacetylase-like amidohydrolase, OCTANEDIOIC ACID HYDROXYAMIDE PHENYLAMIDE, POTASSIUM ION, ... | Authors: | Nielsen, T.K, Hildmann, C, Dickmanns, A, Schwienhorst, A, Ficner, R. | Deposit date: | 2005-06-13 | Release date: | 2005-11-29 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.57 Å) | Cite: | Crystal structure of a bacterial class 2 histone deacetylase homologue J.Mol.Biol., 354, 2005
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1G8Y
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![BU of 1g8y by Molmil](/molmil-images/mine/1g8y) | CRYSTAL STRUCTURE OF THE HEXAMERIC REPLICATIVE HELICASE REPA OF PLASMID RSF1010 | Descriptor: | REGULATORY PROTEIN REPA | Authors: | Niedenzu, T, Roeleke, D, Bains, G, Scherzinger, E, Saenger, W. | Deposit date: | 2000-11-21 | Release date: | 2001-02-14 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of the hexameric replicative helicase RepA of plasmid RSF1010. J.Mol.Biol., 306, 2001
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1IER
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![BU of 1ier by Molmil](/molmil-images/mine/1ier) | CUBIC CRYSTAL STRUCTURE OF NATIVE HORSE SPLEEN FERRITIN | Descriptor: | CADMIUM ION, FERRITIN | Authors: | Granier, T, Gallois, B, Dautant, A, Langlois D'Estaintot, B, Precigoux, G. | Deposit date: | 1996-05-28 | Release date: | 1997-01-11 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.26 Å) | Cite: | Comparison of the structures of the cubic and tetragonal forms of horse-spleen apoferritin. Acta Crystallogr.,Sect.D, 53, 1997
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1LB3
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![BU of 1lb3 by Molmil](/molmil-images/mine/1lb3) | Structure of recombinant mouse L chain ferritin at 1.2 A resolution | Descriptor: | CADMIUM ION, FERRITIN LIGHT CHAIN 1, GLYCEROL, ... | Authors: | Granier, T, Langlois D'Estaintot, B, Gallois, B, Chevalier, J.-M, Precigoux, G, Santambrogio, P, Arosio, P. | Deposit date: | 2002-04-02 | Release date: | 2003-01-28 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.21 Å) | Cite: | Structural description of the active sites of mouse L-chain ferritin at 1.2A resolution J.Biol.Inorg.Chem., 8, 2003
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2H0K
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![BU of 2h0k by Molmil](/molmil-images/mine/2h0k) | Crystal Structure of a Mutant of Rat Annexin A5 | Descriptor: | Annexin A5, CALCIUM ION | Authors: | Granier, T, Langlois D'Estaintot, B, Gallois, B, Tessier, B, Brisson, A. | Deposit date: | 2006-05-15 | Release date: | 2007-06-19 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.76 Å) | Cite: | Annexin-A5 assembled into two-dimensional arrays promotes cell membrane repair. Nat Commun, 2, 2011
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3M8V
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![BU of 3m8v by Molmil](/molmil-images/mine/3m8v) | |
1H96
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![BU of 1h96 by Molmil](/molmil-images/mine/1h96) | recombinant mouse L-chain ferritin | Descriptor: | CADMIUM ION, FERRITIN LIGHT CHAIN 1, SULFATE ION | Authors: | Granier, T, Gallois, B, D'Estaintot, B.L, Dautant, A, Chevalier, J.M, Mellado, J.M, Beaumont, C, Santambrogio, P, Arosio, P, Precigoux, G. | Deposit date: | 2001-02-28 | Release date: | 2001-03-06 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structure of Mouse L-Chain Ferritin at 1.6 A Resolution Acta Crystallogr.,Sect.D, 57, 2001
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1OLO
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1SYX
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![BU of 1syx by Molmil](/molmil-images/mine/1syx) | The crystal structure of a binary U5 snRNP complex | Descriptor: | CD2 antigen cytoplasmic tail-binding protein 2, Spliceosomal U5 snRNP-specific 15 kDa protein | Authors: | Nielsen, T.K, Liu, S, Luhrmann, R, Ficner, R. | Deposit date: | 2004-04-02 | Release date: | 2005-10-18 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.345 Å) | Cite: | Structural basis for the bifunctionality of the U5 snRNP 52K protein (CD2BP2). J.Mol.Biol., 369, 2007
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7FCZ
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![BU of 7fcz by Molmil](/molmil-images/mine/7fcz) | Crystal Structure of human RIPK1 kinase domain in complex with a novel inhibitor | Descriptor: | N-[(3S)-7-(2-cyclopropylethynyl)-5-methyl-4-oxidanylidene-2,3-dihydro-1,5-benzoxazepin-3-yl]-5-(phenylmethyl)-4H-1,2,4-triazole-3-carboxamide, Receptor-interacting serine/threonine-protein kinase 1 | Authors: | Su, H.X, Xie, H, Nie, T.Q, Li, M.J, Xu, Y.C. | Deposit date: | 2021-07-15 | Release date: | 2022-01-19 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.21 Å) | Cite: | Potent and Selective RIPK1 Inhibitors Targeting Dual-Pockets for the Treatment of Systemic Inflammatory Response Syndrome and Sepsis. Angew.Chem.Int.Ed.Engl., 61, 2022
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7FD0
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![BU of 7fd0 by Molmil](/molmil-images/mine/7fd0) | Crystal Structure of human RIPK1 kinase domain in complex with a novel inhibitor | Descriptor: | N-[(3S)-5-methyl-7-[2-(oxan-4-yl)ethynyl]-4-oxidanylidene-2,3-dihydro-1,5-benzoxazepin-3-yl]-5-(phenylmethyl)-4H-1,2,4-triazole-3-carboxamide, Receptor-interacting serine/threonine-protein kinase 1 | Authors: | Su, H.X, Xie, H, Nie, T.Q, Li, M.J, Xu, Y.C. | Deposit date: | 2021-07-15 | Release date: | 2022-01-19 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Potent and Selective RIPK1 Inhibitors Targeting Dual-Pockets for the Treatment of Systemic Inflammatory Response Syndrome and Sepsis. Angew.Chem.Int.Ed.Engl., 61, 2022
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8IFQ
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![BU of 8ifq by Molmil](/molmil-images/mine/8ifq) | SARS-CoV-2 3CL protease (3CLpro) in complex with compound 2 | Descriptor: | (1R,2S,5S)-3-[N-(tert-butylcarbamoyl)-3-methyl-L-valyl]-N-{(1Z,2S)-1-imino-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide, 3C-like proteinase nsp5 | Authors: | Su, H.X, Zhao, W.F, Xie, H, Nie, T.Q, Li, M.J, Xu, Y.C. | Deposit date: | 2023-02-19 | Release date: | 2023-10-18 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Structure-based development and preclinical evaluation of the SARS-CoV-2 3C-like protease inhibitor simnotrelvir. Nat Commun, 14, 2023
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