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PDB: 66 results

6GZ9
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BU of 6gz9 by Molmil
Crystal structure of a POT family transporter in complex with prodrug valacyclovir
Descriptor: 2-[(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy]ethyl L-valinate, Peptide ABC transporter permease
Authors:Minhas, G.S, Newstead, S.
Deposit date:2018-07-03
Release date:2018-12-26
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural basis for prodrug recognition by the SLC15 family of proton-coupled peptide transporters.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
6EXS
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BU of 6exs by Molmil
Crystal structure of a POT family transporter in complex with thioalcohol conjugated peptide.
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 2-[[(2~{R})-2-azanyl-3-[(3~{S})-3-methyl-1-oxidanyl-hexan-3-yl]sulfanyl-propanoyl]amino]ethanoic acid, Peptide ABC transporter permease
Authors:Minhas, G.S, Newstead, S.
Deposit date:2017-11-09
Release date:2018-06-27
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis of malodour precursor transport in the human axilla.
Elife, 7, 2018
4APS
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BU of 4aps by Molmil
Crystal structure of a POT family peptide transporter in an inward open conformation.
Descriptor: CADMIUM ION, DI-OR TRIPEPTIDE H+ SYMPORTER
Authors:Solcan, N, Kwok, J, Fowler, P.W, Cameron, A.D, Drew, D, Iwata, S, Newstead, S.
Deposit date:2012-04-05
Release date:2012-06-13
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Alternating Access Mechanism in the Pot Family of Oligopeptide Transporters.
Embo J., 31, 2012
2W1B
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BU of 2w1b by Molmil
The structure of the efflux pump AcrB in complex with bile acid
Descriptor: (3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC ACID, ACRIFLAVIN RESISTANCE PROTEIN B
Authors:Drew, D, Klepsch, M.M, Newstead, S, Flaig, R, De Gier, J.W, Iwata, S, Beis, K.
Deposit date:2008-10-17
Release date:2008-12-09
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.85 Å)
Cite:The Structure of the Efflux Pump Acrb in Complex with Bile Acid.
Mol.Membr.Biol., 25, 2008
4D2B
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BU of 4d2b by Molmil
Structure of a ligand free POT family peptide transporter
Descriptor: (2R)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, DI-OR TRIPEPTIDE:H+ SYMPORTER, ...
Authors:Lyons, J.A, Parker, J.L, Solcan, N, Brinth, A, Li, D, Shah, S.T.A, Caffrey, M, Newstead, S.
Deposit date:2014-05-09
Release date:2014-06-25
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural Basis for Polyspecificity in the Pot Family of Proton-Coupled Oligopeptide Transporters.
Embo Rep., 15, 2014
4D2C
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BU of 4d2c by Molmil
Structure of a di peptide bound POT family peptide transporter
Descriptor: (2R)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, ALANINE, ...
Authors:Lyons, J.A, Parker, J.L, Solcan, N, Brinth, A, Li, D, Shah, S.T.A, Caffrey, M, Newstead, S.
Deposit date:2014-05-09
Release date:2014-06-25
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.47 Å)
Cite:Structural Basis for Polyspecificity in the Pot Family of Proton-Coupled Oligopeptide Transporters.
Embo Rep., 15, 2014
6HZP
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BU of 6hzp by Molmil
Crystal structure of a POT family transporter in complex with 5-aminolevulinic acid
Descriptor: 5-azanyl-4-oxidanylidene-pentanoic acid, Peptide ABC transporter permease
Authors:Minhas, G.S, Newstead, S.
Deposit date:2018-10-23
Release date:2018-12-26
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for prodrug recognition by the SLC15 family of proton-coupled peptide transporters.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
4D2D
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BU of 4d2d by Molmil
Structure of a tri peptide bound POT family peptide transporter
Descriptor: (2R)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, ALANINE-TRIPEPTIDE, ...
Authors:Lyons, J.A, Parker, J.L, Solcan, N, Brinth, A, Li, D, Shah, S.T.A, Caffrey, M, Newstead, S.
Deposit date:2014-05-09
Release date:2014-06-25
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.522 Å)
Cite:Structural Basis for Polyspecificity in the Pot Family of Proton-Coupled Oligopeptide Transporters.
Embo Rep., 15, 2014
7ZI0
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BU of 7zi0 by Molmil
Structure of human Smoothened in complex with cholesterol and SAG
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-chloro-N-[trans-4-(methylamino)cyclohexyl]-N-{[3-(pyridin-4-yl)phenyl]methyl}-1-benzothiophene-2-carboxamide, CHOLESTEROL, ...
Authors:Byrne, E.F.X, Woolley, R.E, Ansell, B, Sansom, M.S.P, Newstead, S, Siebold, C.
Deposit date:2022-04-07
Release date:2022-06-15
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (3 Å)
Cite:Patched 1 regulates Smoothened by controlling sterol binding to its extracellular cysteine-rich domain.
Sci Adv, 8, 2022
5A2N
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BU of 5a2n by Molmil
Crystal structure of the nitrate transporter NRT1.1 from Arabidopsis thaliana.
Descriptor: PROTEIN NRT1/ PTR FAMILY 6.3
Authors:Parker, J.L, Newstead, S.
Deposit date:2015-05-20
Release date:2015-06-17
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Molecular Basis of Nitrate Uptake by the Plant Nitrate Transporter Nrt1.1.
Nature, 507, 2014
5A2O
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BU of 5a2o by Molmil
Crystal structure of the nitrate transporter NRT1.1 from Arabidopsis thaliana in complex with nitrate.
Descriptor: NITRATE ION, NITRATE TRANSPORTER 1.1
Authors:Parker, J.L, Newstead, S.
Deposit date:2015-05-20
Release date:2015-06-17
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.71 Å)
Cite:Molecular Basis of Nitrate Uptake by the Plant Nitrate Transporter Nrt1.1.
Nature, 507, 2014
5A43
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BU of 5a43 by Molmil
Crystal structure of a dual topology fluoride ion channel.
Descriptor: DECYL-BETA-D-MALTOPYRANOSIDE, FLUORIDE ION, MONOBODIES, ...
Authors:Stockbridge, R.B, Kolmakova-Partensky, L, Shane, T, Koide, A, Koide, S, Miller, C, Newstead, S.
Deposit date:2015-06-04
Release date:2015-09-02
Last modified:2015-09-30
Method:X-RAY DIFFRACTION (2.58 Å)
Cite:Crystal Structures of a Double-Barrelled Fluoride Ion Channel.
Nature, 525, 2015
5A40
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BU of 5a40 by Molmil
Crystal structure of a dual topology fluoride ion channel.
Descriptor: MERCURY (II) ION, MONOBODIES, PUTATIVE FLUORIDE ION TRANSPORTER CRCB
Authors:Stockbridge, R.B, Kolmakova-Partensky, L, Shane, T, Koide, A, Koide, S, Miller, C, Newstead, S.
Deposit date:2015-06-04
Release date:2015-09-02
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Crystal Structures of a Double-Barrelled Fluoride Ion Channel.
Nature, 525, 2015
5A9H
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BU of 5a9h by Molmil
Crystal structure of the extracellular domain of PepT2
Descriptor: ACETATE ION, CESIUM ION, GLYCEROL, ...
Authors:Beale, J.H, Newstead, S.
Deposit date:2015-07-21
Release date:2015-09-09
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Crystal Structures of the Extracellular Domain from Pept1 and Pept2 Provide Novel Insights Into Mammalian Peptide Transport
Structure, 23, 2015
5A9D
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BU of 5a9d by Molmil
Crystal structure of the extracellular domain of PepT1
Descriptor: GLYCEROL, SOLUTE CARRIER FAMILY 15 MEMBER 1
Authors:Beale, J.H, Bird, L.E, Owens, R.J, Newstead, S.
Deposit date:2015-07-20
Release date:2015-09-09
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structures of the Extracellular Domain from Pept1 and Pept2 Provide Novel Insights Into Mammalian Peptide Transport
Structure, 23, 2015
5A9I
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BU of 5a9i by Molmil
Crystal structure of the extracellular domain of PepT2
Descriptor: CITRIC ACID, GLYCEROL, SOLUTE CARRIER FAMILY 15 MEMBER 2
Authors:Beale, J.H, Newstead, S.
Deposit date:2015-07-21
Release date:2015-09-09
Last modified:2019-10-09
Method:X-RAY DIFFRACTION (2.84 Å)
Cite:Crystal Structures of the Extracellular Domain from Pept1 and Pept2 Provide Novel Insights Into Mammalian Peptide Transport
Structure, 23, 2015
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